Brief Information of the Compound and Protein
Compound Name
4-(1-benzofuran-5-yl)pyridine-2,6-diamine
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PubChem ID
CID: 155920134
Canonical SMILES
Nc1cc(cc(N)n1)-c1ccc2occc2c1
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Compound Formula C13H11N3O
Compound Structure
Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
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CMGC protein kinase DYRK family
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CMGC protein kinase Dyrk1 subfamily
Uniprot ID
Q13627
Gene Name
DYRK1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM