| Compound ID |
Compound Name |
Compound Formula |
|
CP0517204
|
N-[(3S,4S)-1-cyclohexyl-3-(2-pyridin-2-ylpropan-2-ylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C30H35F2N5O3
|
1
|
| 1 |
IC50 = 0.37 nM
|
|
|
|
CP0537080
|
N-[(3S,4S)-1-(cyclobutylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C28H30F2N6O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0563822
|
N-[(3S,4S)-1-cyclohexyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C29H32F2N6O3
|
1
|
| 1 |
IC50 = 0.75 nM
|
|
|
|
CP0517201
|
N-[(3S,4S)-1-(cyclopropylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C27H28F2N6O3
|
14
|
| 1 |
IC50 = 0.864 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
| 3 |
IC50 = 0.903 nM
|
|
|
| 4 |
IC50 = 0.962 nM
|
|
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| 5 |
IC50 = 0.985 nM
|
|
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| 6 |
IC50 = 0.989 nM
|
|
|
| 7 |
IC50 = 1.15 nM
|
|
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| 8 |
IC50 = 1.65 nM
|
|
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| 9 |
IC50 = 1.84 nM
|
|
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| 10 |
IC50 = 2.03 nM
|
|
|
| 11 |
IC50 = 2.32 nM
|
|
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| 12 |
IC50 = 2.79 nM
|
|
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| 13 |
IC50 = 2.83 nM
|
|
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| 14 |
IC50 = 3.2 nM
|
|
|
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CP0558456
|
N-[(3S,4S)-1-cyclopentyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C28H30F2N6O3
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0537172
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-[(1-methylcyclopropyl)methyl]-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
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|
C28H30F2N6O3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0560993
|
N-[(3S,4S)-1-cyclohexyl-3-(2-phenylethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C30H34F2N4O3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0538277
|
N-[(3S,4S)-1-cyclohexyl-3-[(1-pyridin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C30H33F2N5O3
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0551804
|
N-[(3S,4S)-1-cyclohexyl-3-[[(1R)-1-phenylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C30H34F2N4O3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0563821
|
N-[(3S,4S)-1-cyclohexyl-3-(2-pyridin-2-ylethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C29H33F2N5O3
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0569222
|
N-[(3S,4S)-1-cyclohexyl-3-[methyl(2-phenylethyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C31H36F2N4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0551802
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-propyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
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|
C26H28F2N6O3
|
1
|
| 1 |
IC50 = 18.4 nM
|
|
|
|
CP0554599
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-propan-2-yl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
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|
C26H28F2N6O3
|
1
|
| 1 |
IC50 = 20.5 nM
|
|
|
|
CP0558270
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-[(1-fluorocyclopropyl)methyl]-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
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|
C27H27F3N6O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0560994
|
N-[(3S,4S)-1-cyclobutyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C27H28F2N6O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0444874
|
N-[(3R,4R)-1-cyclohexyl-3-(dimethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C24H30F2N4O3
|
1
|
| 1 |
IC50 = 37.6 nM
|
|
|
|
CP0537076
|
N-[(3S,4S)-1-cyclohexyl-3-[[(1S)-2-hydroxy-1-phenylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C30H34F2N4O4
|
1
|
| 1 |
IC50 = 43.1 nM
|
|
|
|
CP0572606
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-ethyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C25H26F2N6O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0444872
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-(2-methoxyethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H28F2N6O4
|
1
|
| 1 |
IC50 = 49.2 nM
|
|
|
|
CP0557144
|
N-[(3S,4S)-1-cyclohexyl-3-(pyridin-2-ylmethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C28H31F2N5O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0537065
|
N-[(3S,4S)-1-cyclohexyl-3-methoxypiperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C22H27F2N3O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0560992
|
N-[(3S,4S)-1-cyclohexyl-3-(methylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C23H28F2N4O3
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0574402
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-(3-fluoropropyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H27F3N6O3
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0517217
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-methyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C24H24F2N6O3
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0517215
|
N-[(3S,4S)-1-cyclohexyl-3-[ethyl(methyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C25H32F2N4O3
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0537063
|
N-[(3S,4S)-1-cyclohexyl-3-ethoxypiperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C23H29F2N3O3
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0554755
|
N-[(3S,4S)-1-cyclohexyl-3-hydroxypiperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C21H25F2N3O3
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0517214
|
N-[(3S,4S)-3-carbamoyl-1-cyclohexylpiperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C22H26F2N4O3
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0554598
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C23H22F2N6O3
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
|
CP0557143
|
N-[(3S,4S)-3-(azetidine-1-carbonyl)-1-cyclohexylpiperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C25H30F2N4O3
|
1
|
| 1 |
IC50 = 201 nM
|
|
|
|
CP0558454
|
N-(1-cyclohexylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,3,4-oxadiazole-2-carboxamide
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|
C20H24F2N4O2
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0444885
|
methyl (3S,4S)-1-cyclohexyl-4-[[5-(2,4-difluorophenyl)-1,2-oxazole-3-carbonyl]amino]piperidine-3-carboxylate
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|
C23H27F2N3O4
|
1
|
| 1 |
IC50 = 206 nM
|
|
|
|
CP0517199
|
N-(1-benzylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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|
C22H21F2N3O2
|
1
|
| 1 |
IC50 = 239 nM
|
|
|
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CP0575257
|
N-[(3S,4S)-1-cyclohexyl-3-[2-methoxyethyl(methyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H34F2N4O4
|
1
|
| 1 |
IC50 = 282 nM
|
|
|
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CP0537061
|
N-[(3S,4S)-1-cyclohexyl-3-(hydroxymethyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C22H27F2N3O3
|
1
|
| 1 |
IC50 = 324 nM
|
|
|
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CP0572605
|
N-[(3R,4R)-1-cyclohexyl-3-[[(1R)-1-pyridin-2-ylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C29H33F2N5O3
|
1
|
| 1 |
IC50 = 353 nM
|
|
|
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CP0575258
|
N-[(3R,4R)-1-cyclohexyl-3-[[(1S)-1-pyridin-2-ylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C29H33F2N5O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0537074
|
N-[(3S,4S)-1-cyclohexyl-3-(2-hydroxyethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C24H30F2N4O4
|
1
|
| 1 |
IC50 = 429 nM
|
|
|
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CP0444871
|
N-(1-cyclohexylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C21H25F2N3O2
|
1
|
| 1 |
IC50 = 463 nM
|
|
|
|
CP0552289
|
N-[(3S,4S)-1-cyclopropyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H26F2N6O3
|
1
|
| 1 |
IC50 = 554 nM
|
|
|
|
CP0554756
|
N-(1-cyclohexylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2,4-oxadiazole-3-carboxamide
Show/Hide
|
C20H24F2N4O2
|
1
|
| 1 |
IC50 = 554 nM
|
|
|
|
CP0572604
|
N-[(3S,4S)-1-cyclohexyl-3-(pyrrolidine-1-carbonyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H32F2N4O3
|
1
|
| 1 |
IC50 = 764 nM
|
|
|
|
CP0554757
|
N-(1-cyclohexylpiperidin-4-yl)-3-(2,4-difluorophenyl)-1,2-oxazole-5-carboxamide
Show/Hide
|
C21H25F2N3O2
|
1
|
| 1 |
IC50 = 889 nM
|
|
|
|
CP0537071
|
N-(1-cyclohexylpiperidin-4-yl)-1-(2,4-difluorophenyl)triazole-4-carboxamide
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|
C20H25F2N5O
|
1
|
| 1 |
IC50 = 936 nM
|
|
|
|
CP0537075
|
N-[(3S,4S)-1-cyclohexyl-3-(phenylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C28H30F2N4O3
|
1
|
| 1 |
IC50 = 968 nM
|
|
|
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CP0574635
|
N-[(3S,4S)-1-(3,3-difluorocyclobutyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C27H26F4N6O3
|
1
|
| 1 |
IC50 = 975 nM
|
|
|
|
CP0569223
|
N-[(3S,4S)-1-cyclohexyl-3-[[(1S)-1-pyridin-2-ylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C29H33F2N5O3
|
1
|
| 1 |
IC50 = 981 nM
|
|
|
|
CP0537069
|
N-(1-cyclopentylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C20H23F2N3O2
|
1
|
| 1 |
IC50 = 993 nM
|
|
|
|
CP0554596
|
N-(1-cyclobutylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C19H21F2N3O2
|
1
|
| 1 |
IC50 = 1060 nM
|
|
|
|
CP0517205
|
N-[(3S,4S)-1-acetyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C25H24F2N6O4
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0517203
|
(3S,4S)-1-cyclohexyl-4-[[5-(2,4-difluorophenyl)-1,2-oxazole-3-carbonyl]amino]piperidine-3-carboxylic acid
Show/Hide
|
C22H25F2N3O4
|
1
|
| 1 |
IC50 = 1620 nM
|
|
|
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CP0563823
|
N-[(3R,4S)-1-(cyclopropylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C27H28F2N6O3
|
1
|
| 1 |
IC50 = 2250 nM
|
|
|
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CP0444873
|
N-(1-cyclohexylpiperidin-4-yl)-6-(2,4-difluorophenyl)pyrimidine-4-carboxamide
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|
C22H26F2N4O
|
1
|
| 1 |
IC50 = 3060 nM
|
|
|
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CP0552714
|
N-(1-cyclohexylpiperidin-4-yl)-1-(2,4-difluorophenyl)pyrazole-4-carboxamide
Show/Hide
|
C21H26F2N4O
|
1
|
| 1 |
IC50 = 3160 nM
|
|
|
|
CP0560991
|
5-(2,4-difluorophenyl)-N-piperidin-4-yl-1,2-oxazole-3-carboxamide
Show/Hide
|
C15H15F2N3O2
|
1
|
| 1 |
IC50 = 3180 nM
|
|
|
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CP0569221
|
5-(2,4-difluorophenyl)-N-[1-(2-methoxyethyl)piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C18H21F2N3O3
|
1
|
| 1 |
IC50 = 9480 nM
|
|
|
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CP0560996
|
N-[(3S,4R)-1-(cyclopropylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C27H28F2N6O3
|
1
|
| 1 |
IC50 > 5500 nM
|
|
|
