Brief Information of the Compound and Protein
Compound Name
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-[(1-methylcyclopropyl)methyl]-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
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PubChem ID
CID: 141678081
Canonical SMILES
CC1(CN2CC[C@H](NC(=O)c3cc(on3)-c3ccc(F)cc3F)[C@H](C2)C(=O)NC2(CC2)c2ncccn2)CC1
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Compound Formula C28H30F2N6O3
Compound Structure
Protein Name
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 2.7 nM
   TI
   LI
   LO
   TS