Brief Information of the Compound and Protein
Compound Name
N-(1-cyclobutylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
    Show/Hide
Canonical SMILES
Fc1ccc(-c2cc(no2)C(=O)NC2CCN(CC2)C2CCC2)c(F)c1
    Show/Hide
Compound Formula C19H21F2N3O2
Compound Structure
Protein Name
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 1060 nM
   TI
   LI
   LO
   TS