| Compound ID |
Compound Name |
Compound Formula |
|
CP0433403
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-cyclopropyl-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
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|
C29H32F6N2O2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0433404
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
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|
C31H31F5N2O2
|
1
|
| 1 |
IC50 = 3630 nM
|
|
|
|
CP0376513
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C33H33F7N2O2
|
1
|
| 1 |
IC50 = 3670 nM
|
|
|
|
CP0431450
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C33H33F7N2O3
|
1
|
| 1 |
IC50 = 4160 nM
|
|
|
|
CP0415033
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C32H33F5N2O3
|
1
|
| 1 |
IC50 = 4630 nM
|
|
|
|
CP0448948
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C27H30F6N2O2
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0415035
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C32H33F5N2O2
|
1
|
| 1 |
IC50 = 8010 nM
|
|
|
|
CP0433402
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
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|
C32H31F7N2O2
|
1
|
| 1 |
IC50 = 11200 nM
|
|
|
|
CP0433401
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C27H30F6N2O3
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0666580
|
Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium chloride(TAK-779)
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|
C33H39ClN2O2
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0494800
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
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|
C26H28F6N2O2
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0385865
|
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-methoxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C26H30F4N2O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0415034
|
2-(4-fluorophenyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(6-hydroxyspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C31H31F5N2O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0494796
|
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-(3-methylspiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-yl)butanamide
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|
C26H30F4N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0494799
|
N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
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|
C25H28F4N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
