| Compound ID |
Compound Name |
Compound Formula |
|
CP0167775
|
6-(2-aminopyrimidin-5-yl)-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C15H16N8O2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0015891
|
5-[5-chloro-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C20H26ClN9O3S
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0019596
|
5-[3-bromo-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C20H26BrN9O3S
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0002073
|
5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C20H27N9O3S
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0169553
|
6-(2-aminopyrimidin-5-yl)-N-[3-(dimethylamino)propyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C20H27N9O2
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0019698
|
5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]-4-(trifluoromethyl)pyrimidin-2-amine
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|
C21H26F3N9O3S
|
1
|
| 1 |
IC50 = 10.2 nM
|
|
|
|
CP0154471
|
6-(2-aminopyrimidin-5-yl)-N-(2-methoxyethyl)-3-methyl-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C19H24N8O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0169552
|
6-(2-aminopyrimidin-5-yl)-N-(2-methoxyethyl)-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C18H22N8O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0021527
|
5-[3-methyl-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C21H29N9O3S
|
1
|
| 1 |
IC50 = 15.4 nM
|
|
|
|
CP0157210
|
6-(2-aminopyrimidin-5-yl)-N-(3-methoxypropyl)-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C19H24N8O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0154469
|
6-(2-aminopyrimidin-5-yl)-N-[2-(dimethylamino)ethyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C19H25N9O2
|
1
|
| 1 |
IC50 = 30.3 nM
|
|
|
|
CP0167778
|
6-(2-aminopyrimidin-5-yl)-8-morpholin-4-yl-N-(oxan-4-yl)imidazo[1,2-a]pyrazine-2-carboxamide
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|
C20H24N8O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0167773
|
6-(2-aminopyrimidin-5-yl)-8-morpholin-4-yl-N-(2-morpholin-4-ylethyl)imidazo[1,2-a]pyrazine-2-carboxamide
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|
C21H27N9O3
|
1
|
| 1 |
IC50 = 34.3 nM
|
|
|
|
CP0238436
|
6-(2-aminopyrimidin-5-yl)-5-chloro-N-(2-methoxyethyl)-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C18H21ClN8O3
|
1
|
| 1 |
IC50 = 35.1 nM
|
|
|
|
CP0238435
|
6-(2-aminopyrimidin-5-yl)-N-(4-hydroxycyclohexyl)-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C21H26N8O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0028795
|
5-[2-[(4-ethylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C21H29N9O3S
|
1
|
| 1 |
IC50 = 98.5 nM
|
|
|
|
CP0022554
|
5-[2-[[(3S)-3-methyl-4-methylsulfonylpiperazin-1-yl]methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C21H29N9O3S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0030764
|
5-[2-[[(2S,6R)-2,6-dimethyl-4-methylsulfonylpiperazin-1-yl]methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
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|
C22H31N9O3S
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0009496
|
N-[3-(dimethylamino)propyl]-6-(1H-indazol-4-yl)-8-morpholin-4-ylimidazo[1,2-a]pyrazine-2-carboxamide
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|
C23H28N8O2
|
1
|
| 1 |
IC50 = 429 nM
|
|
|
|
CP0028794
|
1-[4-[[6-(2-aminopyrimidin-5-yl)-8-morpholin-4-ylimidazo[1,2-a]pyrazin-2-yl]methyl]piperazin-1-yl]-2-(dimethylamino)ethanone
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|
C23H32N10O2
|
1
|
| 1 |
IC50 = 480 nM
|
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