| Compound ID |
Compound Name |
Compound Formula |
|
CP0006340
|
Dinaciclib
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|
C21H28N6O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0644708
|
(S)-6-(1H-Imidazo[4,5-b]pyridin-1-yl)-N-(5-((1-methylpyrrolidin-2-yl)methoxy)pyridin-2-yl)pyrimidin-4-amine
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|
C21H22N8O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0028319
|
6-imidazo[4,5-b]pyridin-1-yl-N-[5-(2-piperidin-1-ylethoxy)pyridin-2-yl]pyrimidin-4-amine
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|
C22H24N8O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0644899
|
N-(5-(2-(dimethylamino)ethoxy)pyridin-2-yl)-6-(1H-imidazo[4,5-b]pyridin-1-yl)pyrimidin-4-amine
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|
C19H20N8O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0639858
|
N-(5-(2-(dimethylamino)ethoxy)pyridin-2-yl)-6-(6-methyl-1H-benzo[d]imidazol-1-yl)pyrimidin-4-amine
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|
C21H23N7O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0633715
|
(R)-6-(1H-Benzo[d]imidazol-1-yl)-N-(5-((1-methylpyrrolidin-2-yl)methoxy)pyridin-2-yl)pyrimidin-4-amine
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|
C22H23N7O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0639657
|
(S)-6-(1H-Benzo[d]imidazol-1-yl)-N-(5-((1-methylpyrrolidin-2-yl)methoxy)pyridin-2-yl)pyrimidin-4-amine
Show/Hide
|
C22H23N7O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0633452
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(2-(piperidin-1-yl)ethoxy)pyridin-2-yl)pyrimidin-4-amine
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|
C23H25N7O
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0633583
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(2-(dimethylamino)ethoxy)pyridin-2-yl)pyrimidin-4-amine
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|
C20H21N7O
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0644897
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(3-(dimethylamino)propoxy)pyridin-2-yl)pyrimidin-4-amine
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|
C21H23N7O
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0643287
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(3-(dimethylamino)propyl)pyridin-2-yl)pyrimidin-4-amine
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|
C21H23N7
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0645094
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(2-morpholinoethoxy)pyridin-2-yl)pyrimidin-4-amine
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|
C22H23N7O2
|
1
|
| 1 |
IC50 = 295 nM
|
|
|
|
CP0639128
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(4-methylpiperazin-1-yl)pyridin-2-yl)pyrimidin-4-amine
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|
C21H22N8
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0644556
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-4-amine
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|
C23H26N8
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
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CP0963734
|
N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)piperazine-1-carboxamide
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|
C16H23N5O2S2
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0645041
|
N-(5-(2-(Dimethylamino)ethoxy)pyridin-2-yl)-6-(3H-imidazo[4,5-b]pyridin-3-yl)pyrimidin-4-amine
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|
C19H20N8O
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0639782
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(pyridin-2-yl)pyrimidin-4-amine
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|
C16H12N6
|
1
|
| 1 |
IC50 = 842 nM
|
|
|
|
CP0639658
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-((1-methylpiperidin-4-yl)oxy)pyridin-2-yl)pyrimidin-4-amine
Show/Hide
|
C22H23N7O
|
1
|
| 1 |
IC50 = 884 nM
|
|
|
|
CP0644555
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(4-(2-(dimethylamino)ethoxy)phenyl)pyrimidin-4-amine
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|
C21H22N6O
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0644898
|
(S)-6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(2,4-dimethylpiperazin-1-yl)pyridin-2-yl)pyrimidin-4-amine
Show/Hide
|
C22H24N8
|
1
|
| 1 |
IC50 = 1380 nM
|
|
|
|
CP0643286
|
2-(4-((6-(1H-Benzo[d]imidazol-1-yl)pyrimidin-4-yl)amino)phenyl)ethanol
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|
C19H17N5O
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0641125
|
N-(5-(2-(Dimethylamino)ethoxy)pyridin-2-yl)-6-(1H-indol-1-yl)pyrimidin-4-amine
Show/Hide
|
C21H22N6O
|
1
|
| 1 |
IC50 = 2330 nM
|
|
|
|
CP0640666
|
N-(5-(2-(dimethylamino)ethoxy)pyridin-2-yl)-6-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrimidin-4-amine
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 = 4280 nM
|
|
|
|
CP0638964
|
N-(5-(2-(Dimethylamino)ethoxy)pyridin-2-yl)-6-(1H-imidazol-1-yl)pyrimidin-4-amine
Show/Hide
|
C16H19N7O
|
1
|
| 1 |
IC50 = 6150 nM
|
|
|
|
CP0644900
|
N-(5-(2-(Dimethylamino)ethoxy)pyridin-2-yl)-6-(quinolin-3-yl)pyrimidin-4-amine
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|
C22H22N6O
|
1
|
| 1 |
IC50 = 17600 nM
|
|
|
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CP0644896
|
N-(5-(2-(Dimethylamino)ethoxy)pyridin-2-yl)-6-(1H-indazol-1-yl)pyrimidin-4-amine
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0644901
|
6-(1H-Benzo[d]imidazol-1-yl)-N-(5-(3-(dimethylamino)propoxy)pyridin-2-yl)-5-methylpyrimidin-4-amine
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
