| Compound ID |
Compound Name |
Compound Formula |
|
CP0489583
|
3-[4-[5-[butyl-[4-(trifluoromethyl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]indol-1-yl]propanoic acid
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|
C25H23F3N4O3S
|
1
|
| 1 |
EC50 = 0.03981 nM
|
|
|
|
CP0407970
|
5-[3-[4-[(2R)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C21H20ClFN4O4
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0094968
|
(2R)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]-2-methylbutanoic acid
Show/Hide
|
C26H24FN3O2S
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0385083
|
(5S)-5-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]piperidin-2-one
Show/Hide
|
C22H23ClFN5O3
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0401223
|
(2R)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]butanoic acid
Show/Hide
|
C25H22FN3O2S
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0481348
|
3-[4-[5-[butyl-[4-(trifluoromethyl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]-1-methylindol-7-yl]propanoic acid
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|
C26H25F3N4O3S
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0275274
|
[(2S)-2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate
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|
C19H34NO5P
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0392507
|
(3S)-3-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]-4-oxobutanoic acid
Show/Hide
|
C25H21FN4O3S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0456276
|
(2S)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]butanoic acid
Show/Hide
|
C25H22FN3O2S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0414068
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,3,4-thiadiazol-2-yl]piperazin-1-yl]-cyclopentylmethanone
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|
C21H27ClFN5O3S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0448173
|
[(2R)-2-amino-3-[5-chloro-4-[3-[4-(cyclopentanecarbonyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl]-2-fluorophenoxy]propyl] dihydrogen phosphate
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|
C21H28ClFN5O7P
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0463002
|
5-[3-[4-[(2R)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxypyridine-3-carbonitrile
Show/Hide
|
C20H19ClFN5O4
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0568116
|
(4S)-4-[[2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]-1,3-oxazolidin-2-one
Show/Hide
|
C21H22FN5O4
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0456275
|
(3R)-3-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]-4-oxobutanoic acid
Show/Hide
|
C25H21FN4O3S
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0380198
|
(4S)-4-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]-1,3-oxazolidin-2-one
Show/Hide
|
C21H21ClFN5O4
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0425159
|
(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]propan-1-ol
Show/Hide
|
C21H24ClFN4O2S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0429681
|
(5R)-5-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]piperidin-2-one
Show/Hide
|
C22H23ClFN5O3
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0468105
|
(5R)-5-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]pyrrolidin-2-one
Show/Hide
|
C22H23ClFN5O3
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0540792
|
(3R,4S)-4-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]oxolan-3-ol
Show/Hide
|
C21H22ClFN4O4
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0450616
|
4-chloro-N-[(1R)-1-(6-chloro-1-ethyl-5-fluorobenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C17H16Cl2FN3O2S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0390012
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclohexylmethanone
Show/Hide
|
C22H29ClFN5O4
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0423754
|
3-[[4-[5-[butyl-[4-(trifluoromethyl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]phenyl]sulfonylamino]propanoic acid
Show/Hide
|
C23H23F3N4O5S2
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0522414
|
N-butyl-N-[5-(1H-indol-4-yl)-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H19F3N4OS
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0486609
|
(4S)-4-[[3-methyl-5-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-2-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
|
C22H25N5O4
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0527519
|
3-[4-[5-[butyl-[4-(trifluoromethyl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]-3-chloroindol-1-yl]propanoic acid
Show/Hide
|
C25H22ClF3N4O3S
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0418780
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclopentylmethanone
Show/Hide
|
C21H27ClFN5O4
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0425164
|
3-[[(1R)-1-[4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]amino]cyclobutane-1-carboxylic acid
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|
C25H29N3O3
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0072186
|
1-((3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidine-3-carboxylic acid
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|
C26H22FN3O2S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0084726
|
2-(4-octylphenethyl)-2-aminopropane-1,3-diol
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|
C19H33NO2
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 7.2 nM
|
|
|
|
CP0392476
|
(2R)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]-4-oxobutanoic acid
Show/Hide
|
C25H21FN4O3S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0392477
|
(2S)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]-4-oxobutanoic acid
Show/Hide
|
C25H21FN4O3S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0392503
|
2-[2-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]ethylamino]acetic acid
Show/Hide
|
C25H22FN3O2S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0414079
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,3,4-thiadiazol-2-yl]piperazin-1-yl]-(3-chlorophenyl)methanone
Show/Hide
|
C22H22Cl2FN5O3S
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0575185
|
(4S)-4-[[3-methyl-5-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyrazin-2-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
|
C20H23N7O4
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0014534
|
(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
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|
C18H38NO5P
|
2
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
EC50 = 18 nM
|
|
|
|
CP0540793
|
(4S)-4-[[4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]-1,3-oxazolidin-2-one
Show/Hide
|
C21H23N5O4
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0496093
|
1-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)-3-methylbenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C27H35N5O3
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0392508
|
(2S)-2-amino-4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]-2-methylbutanoic acid
Show/Hide
|
C26H24FN3O2S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0405808
|
3-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methylamino]propanoic acid
Show/Hide
|
C25H22FN3O2S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0488280
|
2-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methylamino]acetic acid
Show/Hide
|
C24H20FN3O2S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0431497
|
4-cyano-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)imidazo[4,5-c]pyridin-2-yl]ethyl]benzenesulfonamide
Show/Hide
|
C18H16F3N5O2S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0448205
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3,3-dimethylcyclobutyl)methanone
Show/Hide
|
C22H29ClFN5O4
|
1
|
| 1 |
EC50 = 3.1 nM
|
|
|
|
CP0509280
|
(4S)-4-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]pyrrolidin-2-one
Show/Hide
|
C21H21ClFN5O3
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0436469
|
3-[1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinolin-7-yl]propanoic acid
Show/Hide
|
C27H21F3N2O4
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0388815
|
6-cyano-N-[(1R)-1-(6-cyclopropyl-1-ethylimidazo[4,5-c]pyridin-2-yl)ethyl]pyridine-3-sulfonamide
Show/Hide
|
C19H20N6O2S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0456839
|
(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]propan-1-ol
Show/Hide
|
C20H23ClFN5O3
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0386950
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3-chlorophenyl)methanone
Show/Hide
|
C22H22Cl2FN5O4
|
1
|
| 1 |
EC50 = 4.1 nM
|
|
|
|
CP0380201
|
(2R)-2-amino-3-[5-chloro-4-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,2,4-oxadiazol-3-yl]-2-fluorophenoxy]propan-1-ol
Show/Hide
|
C20H20Cl2FN3O4
|
1
|
| 1 |
EC50 = 4.1 nM
|
|
|
|
CP0472547
|
1-[(3R)-3-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]morpholin-4-yl]ethanone
Show/Hide
|
C24H27ClFN5O4
|
1
|
| 1 |
EC50 = 4.1 nM
|
|
|
|
CP0392400
|
4-chloro-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
|
C18H17ClF3N3O2S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0541332
|
4-chloro-N-[(1R)-1-[1-ethyl-6-(hydroxymethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
|
C18H20ClN3O3S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0397742
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3-ethylpyridin-2-yl)methanone
Show/Hide
|
C23H26ClFN6O4
|
1
|
| 1 |
EC50 = 5.3 nM
|
|
|
|
CP0399619
|
2-methoxy-N-[(4-phenyl-3-propan-2-ylphenyl)carbamoyl]benzamide
Show/Hide
|
C24H24N2O3
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0442894
|
4-cyano-N-[(1R)-1-(6-cyclopropyl-1-ethylimidazo[4,5-c]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C20H21N5O2S
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0406127
|
(2R,3S)-2-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]oxolan-3-ol
Show/Hide
|
C22H24ClFN4O4
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0423741
|
N-butyl-N-[5-(7-fluoro-1H-indol-4-yl)-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H18F4N4OS
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
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CP0414066
|
[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C22H23ClFN5O4
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0380954
|
2-methoxy-N-[[4-(2,2,2-trifluoroethoxy)-3-(trifluoromethyl)phenyl]carbamoyl]benzamide
Show/Hide
|
C18H14F6N2O4
|
1
|
| 1 |
EC50 = 6.8 nM
|
|
|
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CP0078455
|
6-cyano-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)imidazo[4,5-c]pyridin-2-yl]ethyl]pyridine-3-sulfonamide
Show/Hide
|
C17H15F3N6O2S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
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CP0446862
|
N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C18H17F4N3O2S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
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CP0486600
|
(4S)-4-[[5-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-2-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
|
C20H22N6O4
|
1
|
| 1 |
EC50 = 7.3 nM
|
|
|
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CP0540794
|
(4S)-4-[[2-methyl-6-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
|
C21H24N6O4
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
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CP0495237
|
N-butyl-N-[5-(1-methylindol-4-yl)-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C23H21F3N4OS
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0391877
|
3-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]propan-1-amine
Show/Hide
|
C24H22FN3S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0436527
|
7-(2-hydroxyethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
|
C26H21F3N2O3
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0551711
|
N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
|
C18H18F3N3O2S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0392403
|
4-cyano-N-[(1R)-1-(1-ethyl-6-methoxyimidazo[4,5-c]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C18H19N5O3S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0442886
|
4-chloro-N-[(1R)-1-(1-ethyl-6-methoxybenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C18H20ClN3O3S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0414076
|
1-[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-3,3,3-trifluoro-2,2-dimethylpropan-1-one
Show/Hide
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C20H24ClF4N5O4
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1
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| 1 |
EC50 = 9.8 nM
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CP0380202
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(5S)-5-[[2,4-dimethyl-6-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxymethyl]pyrrolidin-2-one
Show/Hide
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C24H29N5O3
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1
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| 1 |
EC50 = 11 nM
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CP0415286
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6-((cyclopropylmethyl)(propyl)amino)-N-(1H-indazol-5-yl)pyrimidine-4-carboxamide
Show/Hide
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C19H22N6O
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1
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| 1 |
EC50 = 12 nM
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CP0426135
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[4-[3-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-5-yl]piperazin-1-yl]-(3-chlorophenyl)methanone
Show/Hide
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C22H22Cl2FN5O4
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1
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| 1 |
EC50 = 12 nM
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CP0446864
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4-cyano-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
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C19H17F3N4O2S
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1
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| 1 |
EC50 = 12 nM
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CP0423751
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N-butyl-N-[5-[4-(hydroxymethyl)phenyl]-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C21H20F3N3O2S
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1
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| 1 |
EC50 = 12.59 nM
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CP0379884
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1-(4-(6-Benzylbenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C26H22FNO3
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1
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| 1 |
EC50 = 13 nM
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CP0399620
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2-methoxy-N-[[4-pyridin-2-yl-3-(trifluoromethyl)phenyl]carbamoyl]benzamide
Show/Hide
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C21H16F3N3O3
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1
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| 1 |
EC50 = 13 nM
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CP0430623
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2-methoxy-N-[[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]carbamoyl]benzamide
Show/Hide
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C21H22F3N3O3
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1
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| 1 |
EC50 = 13 nM
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CP0407968
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(2R)-2-amino-3-[5-chloro-4-[5-(5-chloro-6-propan-2-yloxypyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-fluorophenoxy]propan-1-ol
Show/Hide
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C19H19Cl2FN4O4
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1
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| 1 |
EC50 = 13 nM
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CP0534314
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5-[5-[4-[(2R)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,3,4-thiadiazol-2-yl]-2-propan-2-yloxypyridine-3-carbonitrile
Show/Hide
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C20H19ClFN5O3S
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1
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| 1 |
EC50 = 13 nM
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CP0409048
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2-methoxy-N-[[4-propan-2-yl-3-(trifluoromethyl)phenyl]carbamoyl]benzamide
Show/Hide
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C19H19F3N2O3
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1
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| 1 |
EC50 = 14 nM
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CP0380199
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(6R)-6-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]methyl]morpholin-3-one
Show/Hide
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C22H23ClFN5O4
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1
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| 1 |
EC50 = 14 nM
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CP0463062
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[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methanamine
Show/Hide
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C22H18FN3S
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1
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| 1 |
EC50 = 15 nM
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CP0410263
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7-(3-hydroxypropyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C27H23F3N2O3
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1
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| 1 |
EC50 = 15 nM
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CP0410519
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[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclobutylmethanone
Show/Hide
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C20H25ClFN5O4
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1
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| 1 |
EC50 = 17 nM
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CP0385339
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7-(hydroxymethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]-1,6-naphthyridine-3-carboxamide
Show/Hide
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C24H18F3N3O3
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1
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| 1 |
EC50 = 18 nM
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CP0433036
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7-(hydroxymethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C25H19F3N2O3
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1
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| 1 |
EC50 = 18 nM
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CP0456840
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(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]propan-1-ol
Show/Hide
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C20H23ClFN5O2S
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1
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| 1 |
EC50 = 18 nM
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CP0509281
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(4S)-4-[[4-methyl-6-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
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C21H24N6O4
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1
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| 1 |
EC50 = 18 nM
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CP0392504
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4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]-4-oxobutanoic acid
Show/Hide
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C25H20FN3O3S
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1
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| 1 |
EC50 = 19 nM
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CP0136590
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1-methyl-4-oxo-N-[5-phenyl-6-(trifluoromethyl)pyridin-2-yl]-1,6-naphthyridine-3-carboxamide
Show/Hide
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C22H15F3N4O2
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1
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| 1 |
EC50 = 20 nM
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CP0541072
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(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]propan-1-ol
Show/Hide
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C21H24ClFN4O3
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1
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| 1 |
EC50 = 20 nM
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CP0398884
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1-((4-(5-(3-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H20F2N2O2S
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1
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| 1 |
EC50 = 21 nM
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CP0385337
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1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinoline-7-carboxylic acid
Show/Hide
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C25H17F3N2O4
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1
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| 1 |
EC50 = 21 nM
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CP0242679
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1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]-1,6-naphthyridine-3-carboxamide
Show/Hide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 24 nM
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CP0446863
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-4-methylbenzenesulfonamide
Show/Hide
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C19H20F3N3O2S
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1
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| 1 |
EC50 = 24 nM
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CP0450698
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1-[[1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinolin-7-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C29H24F3N3O4
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1
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| 1 |
EC50 = 25 nM
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CP0389003
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1-((3-fluoro-4-(5-(1-phenylcyclopentyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C28H26FN3O2S
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1
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| 1 |
EC50 = 26 nM
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CP0473339
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1-(3-Fluoro-4-(5-(2-methylbenzyl)benzo[d]thiazol-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C26H23FN2O2S
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1
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| 1 |
EC50 = 26 nM
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CP0541338
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]pyridine-4-sulfonamide
Show/Hide
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C17H17F3N4O2S
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1
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| 1 |
EC50 = 26 nM
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CP0450422
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3-chloro-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
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C18H17ClF3N3O2S
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1
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| 1 |
EC50 = 27 nM
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CP0392404
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6-cyano-N-[(1R)-1-(1-ethyl-6-methoxyimidazo[4,5-c]pyridin-2-yl)ethyl]pyridine-3-sulfonamide
Show/Hide
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C17H18N6O3S
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1
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| 1 |
EC50 = 28 nM
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CP0136593
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1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]-1,7-naphthyridine-3-carboxamide
Show/Hide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 29 nM
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CP0398886
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1-((4-(5-(3,4-Difluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H19F3N2O2S
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1
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| 1 |
EC50 = 30 nM
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CP0513109
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]pyridine-3-sulfonamide
Show/Hide
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C17H17F3N4O2S
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1
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| 1 |
EC50 = 30 nM
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CP0522415
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N-butyl-N-[5-(3-chloro-1H-indol-4-yl)-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C22H18ClF3N4OS
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1
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| 1 |
EC50 = 31.62 nM
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CP0548149
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N-butyl-N-[5-[4-[(dimethylamino)methyl]phenyl]-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C23H25F3N4OS
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1
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| 1 |
EC50 = 31.62 nM
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CP0407971
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(2R)-2-amino-3-[5-chloro-4-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-2-fluorophenoxy]propan-1-ol
Show/Hide
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C20H20Cl2FN3O3S
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1
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| 1 |
EC50 = 32 nM
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CP0417506
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(5R)-5-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(2-methylpropyl)pyrimidin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-1-methylpiperidin-2-one
Show/Hide
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C23H25ClFN5O3
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1
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| 1 |
EC50 = 32 nM
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CP0385931
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1-((3-fluoro-4-(5-(1-phenylcyclohexyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C29H28FN3O2S
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1
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| 1 |
EC50 = 33 nM
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CP0389006
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1-(3-fluoro-4-(5-(2-phenylpropan-2-yl)thiazolo[5,4-b]pyridin-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C26H24FN3O2S
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1
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| 1 |
EC50 = 33 nM
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CP0473194
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1-((4-(5-(4-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H20F2N2O2S
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1
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| 1 |
EC50 = 33 nM
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CP0388813
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4-cyano-N-[(1R)-1-(1-ethylimidazo[4,5-c]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
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C17H17N5O2S
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1
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| 1 |
EC50 = 34 nM
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CP0514883
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1-((3-fluoro-4-(5-((S)-1-phenylethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H22FN3O2S
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1
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| 1 |
EC50 = 35 nM
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CP0105272
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4-methoxy-N-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]pyridine-3-carboxamide
Show/Hide
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C21H16F3N3O3
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1
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| 1 |
EC50 = 35 nM
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CP0391882
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4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]butanoic acid
Show/Hide
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C25H22FN3O2S
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1
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| 1 |
EC50 = 36 nM
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CP0425162
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(4S)-4-[[2-methyl-6-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
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C22H25N5O4
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1
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| 1 |
EC50 = 37 nM
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CP0385945
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1-((3-fluoro-4-(5-((R)-1-phenylethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H22FN3O2S
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1
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| 1 |
EC50 = 38 nM
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CP0407755
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1-((3-fluoro-4-(6-(1-phenylcyclopropyl)benzo[d]thiazol-2-yl)phenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C27H23FN2O2S
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1
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| 1 |
EC50 = 38 nM
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CP0409047
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2-methoxy-N-[[4-(1,3-thiazol-2-yl)-3-(trifluoromethyl)phenyl]carbamoyl]benzamide
Show/Hide
|
C19H14F3N3O3S
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1
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| 1 |
EC50 = 38 nM
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CP0385338
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3-[1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]-1,6-naphthyridin-7-yl]propanoic acid
Show/Hide
|
C26H20F3N3O4
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1
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| 1 |
EC50 = 38 nM
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CP0450696
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8-(hydroxymethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C25H19F3N2O3
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1
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| 1 |
EC50 = 39 nM
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CP0389002
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1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H21FN2O2S
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2
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| 1 |
EC50 = 41 nM
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| 2 |
EC50 = 42 nM
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CP0353667
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1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]cinnoline-3-carboxamide
Show/Hide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 41 nM
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CP0321543
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1-((4-(5-(2-Fluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H20F2N2O2S
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1
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| 1 |
EC50 = 42 nM
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CP0398888
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1-((4-(5-(2,4-Difluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H19F3N2O2S
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1
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| 1 |
EC50 = 42 nM
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CP0438194
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1-((4-(5-(2-Chlorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H20ClFN2O2S
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1
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| 1 |
EC50 = 42 nM
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CP0353666
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1-methyl-4-oxo-N-[5-phenyl-6-(trifluoromethyl)pyridin-2-yl]quinoline-3-carboxamide
Show/Hide
|
C23H16F3N3O2
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1
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| 1 |
EC50 = 42 nM
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CP0403666
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1-[[3-fluoro-4-[6-(2-methyl-1,3-thiazolidine-3-carbonyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H22FN3O3S2
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1
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| 1 |
EC50 = 42 nM
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CP0456274
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3-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]anilino]propanoic acid
Show/Hide
|
C24H20FN3O2S
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1
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| 1 |
EC50 = 42 nM
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CP0425163
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(5S)-5-[2-methyl-6-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxypiperidin-2-one
Show/Hide
|
C22H26N6O3
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1
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| 1 |
EC50 = 42 nM
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CP0456273
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2-(2-fluorophenyl)-5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridine
Show/Hide
|
C21H15FN2S
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1
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| 1 |
EC50 = 45 nM
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CP0459606
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[4-[3-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-5-yl]piperidin-1-yl]-cyclopentylmethanone
Show/Hide
|
C22H28ClFN4O4
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1
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| 1 |
EC50 = 45 nM
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CP0456586
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1-[4-[5-[4-(2-amino-3-hydroxypropoxy)-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-2,2-dimethylbutan-1-one
Show/Hide
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C21H29ClFN5O4
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1
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| 1 |
EC50 = 46 nM
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CP0393732
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1-(4-(5-cyclohexylbenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H26FNO3
|
1
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| 1 |
EC50 = 48 nM
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CP0473338
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1-((4-(5-(3-Chlorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H20ClFN2O2S
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1
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| 1 |
EC50 = 49 nM
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CP0390593
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1-[[3-fluoro-4-[6-(2-propan-2-yl-1,3-thiazolidine-3-carbonyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H26FN3O3S2
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1
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| 1 |
EC50 = 49 nM
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CP0463003
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(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-(6-methyl-5-propan-2-yloxypyridin-2-yl)-1,2,4-oxadiazol-3-yl]phenoxy]propan-1-ol
Show/Hide
|
C20H22ClFN4O4
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1
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| 1 |
EC50 = 49 nM
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CP0442888
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4-chloro-N-[(1R)-1-(1-ethylbenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C17H18ClN3O2S
|
1
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| 1 |
EC50 = 50 nM
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CP0385091
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(5R)-5-[2-fluoro-4-[5-[2-methyl-6-(2-methylpropyl)pyrimidin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]piperidin-2-one
Show/Hide
|
C22H24FN5O3
|
1
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| 1 |
EC50 = 50 nM
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CP0520009
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N-butyl-N-[5-[4-(piperazin-1-ylmethyl)phenyl]-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C25H28F3N5OS
|
1
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| 1 |
EC50 = 50.12 nM
|
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CP0512438
|
1-(3-Fluoro-4-(5-(3-methylbenzyl)benzo[d]thiazol-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C26H23FN2O2S
|
1
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| 1 |
EC50 = 54 nM
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CP0414070
|
[4-[3-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-5-yl]piperazin-1-yl]-cyclopentylmethanone
Show/Hide
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C21H27ClFN5O4
|
1
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| 1 |
EC50 = 55 nM
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CP0291779
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1-(4-(5-benzylbenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C26H22FNO3
|
1
|
| 1 |
EC50 = 57 nM
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CP0413798
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3-cyano-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
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C19H17F3N4O2S
|
1
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| 1 |
EC50 = 57 nM
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CP0353659
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1-methyl-4-oxo-N-[4-pyridin-2-yl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 60 nM
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CP0391879
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4-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]butanoic acid
Show/Hide
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C25H21FN2O2S
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1
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| 1 |
EC50 = 62 nM
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CP0509279
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(2R)-2-amino-3-[5-chloro-4-[5-(5-chloro-6-ethoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-fluorophenoxy]propan-1-ol
Show/Hide
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C18H17Cl2FN4O4
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1
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| 1 |
EC50 = 62 nM
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CP0429682
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(4S)-4-[[4-methyl-6-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
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C22H25N5O4
|
1
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| 1 |
EC50 = 63 nM
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CP0548148
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N-butyl-N-[5-[3-(hydroxymethyl)phenyl]-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C21H20F3N3O2S
|
1
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| 1 |
EC50 = 63.1 nM
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CP0385066
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(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-(2-methyl-6-propan-2-yloxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]propan-1-ol
Show/Hide
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C20H22ClFN4O4
|
1
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| 1 |
EC50 = 67 nM
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CP0519802
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2-methoxy-N-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]benzamide
Show/Hide
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C22H17F3N2O3
|
1
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| 1 |
EC50 = 68 nM
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CP0405884
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1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C24H17F3N2O2
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1
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| 1 |
EC50 = 70 nM
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CP0490913
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1-(3-Fluoro-4-(5-(4-methylbenzyl)benzo[d]thiazol-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C26H23FN2O2S
|
1
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| 1 |
EC50 = 77 nM
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CP0481347
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N-butyl-N-[5-(2,3-dihydro-1H-isoindol-5-yl)-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C22H21F3N4OS
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1
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| 1 |
EC50 = 79.43 nM
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CP0450697
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8-(aminomethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C25H20F3N3O2
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1
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| 1 |
EC50 = 81 nM
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CP0406126
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(4S)-4-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]methyl]-1,3-oxazolidin-2-one
Show/Hide
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C21H21ClFN5O3S
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1
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| 1 |
EC50 = 86 nM
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CP0414067
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[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-pyridin-2-ylmethanone
Show/Hide
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C21H22ClFN6O4
|
1
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| 1 |
EC50 = 92 nM
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CP0473334
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1-(4-(6-Benzylbenzo[d]oxazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H21FN2O3
|
1
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| 1 |
EC50 = 94 nM
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CP0538213
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(2R)-2-amino-3-[5-chloro-4-[5-(5-chloro-6-propan-2-yloxypyridin-3-yl)-1,3,4-thiadiazol-2-yl]-2-fluorophenoxy]propan-1-ol
Show/Hide
|
C19H19Cl2FN4O3S
|
1
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| 1 |
EC50 = 100 nM
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CP0545031
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(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-(6-methyl-5-propan-2-yloxypyridin-2-yl)-1,3,4-thiadiazol-2-yl]phenoxy]propan-1-ol
Show/Hide
|
C20H22ClFN4O3S
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1
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| 1 |
EC50 = 105 nM
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CP0385932
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1-(3-fluoro-4-(5-(1-phenylcyclobutyl)thiazolo[5,4-b]pyridin-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C27H24FN3O2S
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1
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| 1 |
EC50 = 119 nM
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CP0538414
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(4S)-4-[[6-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyridin-3-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
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C20H22N6O4
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1
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| 1 |
EC50 = 120 nM
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CP0391880
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3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]aniline
Show/Hide
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C21H16FN3S
|
1
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| 1 |
EC50 = 123 nM
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CP0481346
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N-butyl-4-chloro-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]benzamide
Show/Hide
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C19H17ClFN3OS
|
1
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| 1 |
EC50 = 125.89 nM
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CP0417718
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1-((4-(5-(2,6-Difluorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C25H19F3N2O2S
|
1
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| 1 |
EC50 = 126 nM
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CP0431836
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4-chloro-N-[(1R)-1-(5-cyano-1-ethylbenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
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C18H17ClN4O2S
|
1
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| 1 |
EC50 = 130 nM
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CP0407972
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(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-(2-methyl-6-propan-2-yloxypyridin-4-yl)-1,3,4-thiadiazol-2-yl]phenoxy]propan-1-ol
Show/Hide
|
C20H22ClFN4O3S
|
1
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| 1 |
EC50 = 130 nM
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CP0389001
|
1-((4-(6-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H20FN3O2S
|
1
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| 1 |
EC50 = 138 nM
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CP0385933
|
1-((4-(5-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H20FN3O2S
|
1
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| 1 |
EC50 = 144 nM
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CP0456841
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(3R,4S)-4-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]oxolan-3-ol
Show/Hide
|
C21H22ClFN4O3S
|
1
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| 1 |
EC50 = 147 nM
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CP0398773
|
1-(4-(5-isobutylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H25NO3
|
1
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| 1 |
EC50 = 150 nM
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CP0436528
|
3-[[1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinolin-7-yl]amino]propanoic acid
Show/Hide
|
C27H22F3N3O4
|
1
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| 1 |
EC50 = 150 nM
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CP0429683
|
(4S)-4-[[5-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyrazin-2-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
|
C19H21N7O4
|
1
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| 1 |
EC50 = 150 nM
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CP0380313
|
1-(4-(5-butoxybenzofuran-2-yl)-3-chlorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H24ClNO4
|
1
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| 1 |
EC50 = 158 nM
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CP0500576
|
1-((4-(5-(4-Chlorobenzyl)benzo[d]thiazol-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H20ClFN2O2S
|
1
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| 1 |
EC50 = 159 nM
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CP0564165
|
(5S)-5-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]piperidin-2-one
Show/Hide
|
C22H23ClFN5O2S
|
1
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| 1 |
EC50 = 160 nM
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CP0481868
|
4-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methylamino]butanoic acid
Show/Hide
|
C26H24FN3O2S
|
1
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| 1 |
EC50 = 179 nM
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CP0450699
|
2-[1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinolin-7-yl]acetic acid
Show/Hide
|
C26H19F3N2O4
|
1
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| 1 |
EC50 = 180 nM
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CP0541333
|
4-chloro-N-[(1R)-1-[1-ethyl-5-(hydroxymethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide
Show/Hide
|
C18H20ClN3O3S
|
1
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| 1 |
EC50 = 180 nM
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CP0136591
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1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]-1,8-naphthyridine-3-carboxamide
Show/Hide
|
C23H16F3N3O2
|
1
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| 1 |
EC50 = 190 nM
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CP0450419
|
2-[(1R)-1-[(4-chlorophenyl)sulfonylamino]ethyl]-1-ethylbenzimidazole-5-carboxamide
Show/Hide
|
C18H19ClN4O3S
|
1
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| 1 |
EC50 = 190 nM
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CP0391878
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3-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methyl-methylamino]propanoic acid
Show/Hide
|
C26H24FN3O2S
|
1
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| 1 |
EC50 = 196 nM
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CP0427573
|
1-(4-(5-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H20FN3O2S
|
1
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| 1 |
EC50 = 199 nM
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CP0520007
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N-butyl-4-methyl-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
|
C19H20N4OS
|
1
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| 1 |
EC50 = 199.53 nM
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CP0475593
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1-methyl-4-oxo-N-[4-pyridin-2-yl-3-(trifluoromethyl)phenyl]-1,6-naphthyridine-3-carboxamide
Show/Hide
|
C22H15F3N4O2
|
1
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| 1 |
EC50 = 200 nM
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CP0429684
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(4S)-4-[[5-[5-[2-methyl-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]pyrazin-2-yl]oxymethyl]-1,3-oxazolidin-2-one
Show/Hide
|
C20H22N6O4
|
1
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| 1 |
EC50 = 200 nM
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CP0525075
|
1-methyl-4-oxo-N-[5-pyridin-2-yl-6-(trifluoromethyl)pyridin-2-yl]-1,6-naphthyridine-3-carboxamide
Show/Hide
|
C21H14F3N5O2
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1
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| 1 |
EC50 = 210 nM
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CP0541337
|
4-chloro-N-[1-(1-ethylimidazo[4,5-c]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C16H17ClN4O2S
|
1
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| 1 |
EC50 = 210 nM
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CP0388889
|
4-chloro-N-[1-(4,5-diethyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
Show/Hide
|
C20H23ClN4O2S
|
1
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| 1 |
EC50 = 220 nM
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CP0389000
|
1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H21FN2O2S
|
1
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| 1 |
EC50 = 221 nM
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CP0399618
|
N-[(3-chloro-4-piperidin-1-ylphenyl)carbamoyl]-2-methoxybenzamide
Show/Hide
|
C20H22ClN3O3
|
1
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| 1 |
EC50 = 230 nM
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CP0460017
|
1-[[3-fluoro-4-[6-(1-pyridin-2-ylcyclopropyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H22FN3O2S
|
1
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| 1 |
EC50 = 240 nM
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CP0390011
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3-[5-chloro-4-[3-[4-(cyclopentanecarbonyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl]-2-fluorophenoxy]propanoic acid
Show/Hide
|
C21H24ClFN4O5
|
1
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| 1 |
EC50 = 240 nM
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CP0574389
|
N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-2,4,6-trifluorobenzenesulfonamide
Show/Hide
|
C18H15F6N3O2S
|
1
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| 1 |
EC50 = 240 nM
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CP0078446
|
4-chloro-N-[(1R)-1-(4,5-diethyl-1,2,4-triazol-3-yl)ethyl]benzenesulfonamide
Show/Hide
|
C14H19ClN4O2S
|
1
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| 1 |
EC50 = 250 nM
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CP0380200
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(2R,3S)-2-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]methyl]oxolan-3-ol
Show/Hide
|
C22H24ClFN4O3S
|
1
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| 1 |
EC50 = 250 nM
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CP0423753
|
3-[[3-[5-[butyl-[4-(trifluoromethyl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]phenyl]sulfonylamino]propanoic acid
Show/Hide
|
C23H23F3N4O5S2
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1
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| 1 |
EC50 = 251.19 nM
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CP0495241
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4-chloro-N-(cyclopropylmethyl)-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]benzamide
Show/Hide
|
C19H15ClFN3OS
|
1
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| 1 |
EC50 = 251.19 nM
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CP0520011
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N-[5-(1-benzofuran-7-yl)-1,3,4-thiadiazol-2-yl]-N-butyl-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H18F3N3O2S
|
1
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| 1 |
EC50 = 251.19 nM
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CP0393734
|
1-(4-(5-benzylbenzofuran-2-yl)-2-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C26H22FNO3
|
1
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| 1 |
EC50 = 253 nM
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CP0306592
|
5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole
Show/Hide
|
C20H10F6N2OS
|
1
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| 1 |
EC50 = 270 nM
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CP0380314
|
1-(4-(5-(cyclopropylmethoxy)benzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H22FNO4
|
1
|
| 1 |
EC50 = 290 nM
|
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CP0564164
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(5R)-5-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]piperidin-2-one
Show/Hide
|
C22H23ClFN5O2S
|
1
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| 1 |
EC50 = 300 nM
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CP0319355
|
1-methyl-4-oxo-N-[4-pyridin-3-yl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
|
C23H16F3N3O2
|
1
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| 1 |
EC50 = 310 nM
|
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CP0858360
|
rac-4-chloro-N-(1-(4,5-diethyl-1H-pyrazol-3-yl)ethyl)benzenesulfonamide
Show/Hide
|
C15H20ClN3O2S
|
1
|
| 1 |
EC50 = 310 nM
|
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CP0450620
|
4-chloro-N-[1-(1-ethylimidazo[4,5-b]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C16H17ClN4O2S
|
1
|
| 1 |
EC50 = 310 nM
|
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CP0425161
|
1-[(3R)-3-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]methyl]morpholin-4-yl]ethanone
Show/Hide
|
C24H27ClFN5O3S
|
1
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| 1 |
EC50 = 310 nM
|
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CP0520006
|
N-butyl-2-fluoro-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
|
C18H17FN4OS
|
1
|
| 1 |
EC50 = 316.23 nM
|
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CP0490911
|
1-(4-(5-Benzylbenzo[d]oxazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H21FN2O3
|
1
|
| 1 |
EC50 = 325 nM
|
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CP0486608
|
(5R)-5-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]methyl]pyrrolidin-2-one
Show/Hide
|
C22H23ClFN5O2S
|
1
|
| 1 |
EC50 = 330 nM
|
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CP0388887
|
4-chloro-N-[1-(5-ethyl-4-methyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
Show/Hide
|
C19H21ClN4O2S
|
1
|
| 1 |
EC50 = 340 nM
|
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CP0398775
|
1-(4-(5-phenethylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C27H25NO3
|
1
|
| 1 |
EC50 = 354 nM
|
|
|
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CP0385335
|
8-(2-hydroxyethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
|
C26H21F3N2O3
|
1
|
| 1 |
EC50 = 390 nM
|
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CP0573385
|
4-chloro-N-[1-(4,5-diethyl-1,2,4-triazol-3-yl)ethyl]benzenesulfonamide
Show/Hide
|
C14H19ClN4O2S
|
1
|
| 1 |
EC50 = 410 nM
|
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CP0456587
|
[4-[5-[4-[(2R)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclopentylmethanone
Show/Hide
|
C21H27ClFN5O4
|
1
|
| 1 |
EC50 = 420 nM
|
|
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CP0446868
|
N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-3-methyl-1-propylpyrazole-4-sulfonamide
Show/Hide
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C19H24F3N5O2S
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1
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| 1 |
EC50 = 420 nM
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CP0380311
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1-((6-(5-cyclohexylbenzofuran-2-yl)pyridin-3-yl)methyl)azetidine-3-carboxylic acid
Show/Hide
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C24H26N2O3
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1
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| 1 |
EC50 = 424 nM
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CP0412287
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1-(4-(5-benzylthiazolo[5,4-c]pyridin-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C24H20FN3O2S
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1
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| 1 |
EC50 = 429 nM
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CP0401204
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1-[[4-[6-(2,2-dimethyl-1,3-thiazolidine-3-carbonyl)-1,3-benzothiazol-2-yl]-3-fluorophenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C24H24FN3O3S2
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1
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| 1 |
EC50 = 430 nM
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CP0380955
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N-[(3-chloro-4-piperidin-1-ylphenyl)carbamothioyl]-2-methoxybenzamide
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C20H22ClN3O2S
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1
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| 1 |
EC50 = 430 nM
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CP0450423
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1-ethyl-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-5-methylpyrazole-4-sulfonamide
Show/Hide
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C18H22F3N5O2S
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1
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| 1 |
EC50 = 430 nM
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CP0319354
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1-methyl-4-oxo-N-[4-pyridin-4-yl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 450 nM
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CP0398778
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1-(4-(5-(cyclopentylmethoxy)benzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H26FNO4
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1
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| 1 |
EC50 = 454 nM
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CP0380309
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1-(4-(5-cyclohexylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H27NO3
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1
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| 1 |
EC50 = 460 nM
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CP0397756
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4-chloro-N-[1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
Show/Hide
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C19H21ClN4O2S
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1
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| 1 |
EC50 = 460 nM
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CP0391876
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2-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]ethanamine
Show/Hide
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C23H20FN3S
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1
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| 1 |
EC50 = 478 nM
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CP0494584
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4-chloro-N-[1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)-2-(4-fluorophenyl)ethyl]benzenesulfonamide
Show/Hide
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C19H20ClFN4O2S
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1
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| 1 |
EC50 = 490 nM
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CP0481350
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N-butyl-2-chloro-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C18H17ClN4OS
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1
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| 1 |
EC50 = 501.19 nM
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CP0472548
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(6R)-6-[[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]methyl]morpholin-3-one
Show/Hide
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C22H23ClFN5O3S
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1
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| 1 |
EC50 = 550 nM
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CP0540790
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(4S)-4-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]pyrrolidin-2-one
Show/Hide
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C21H21ClFN5O2S
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1
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| 1 |
EC50 = 560 nM
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CP0500205
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1-[[3-fluoro-4-[6-(1-pyridin-2-ylethyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C25H22FN3O2S
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1
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| 1 |
EC50 = 570 nM
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CP0541339
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1-ethyl-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]pyrazole-4-sulfonamide
Show/Hide
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C17H20F3N5O2S
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1
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| 1 |
EC50 = 590 nM
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CP0463004
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(2R)-2-amino-3-[5-chloro-4-[5-(5-chloro-6-ethoxypyridin-3-yl)-1,3,4-thiadiazol-2-yl]-2-fluorophenoxy]propan-1-ol
Show/Hide
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C18H17Cl2FN4O3S
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1
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| 1 |
EC50 = 594 nM
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CP0380310
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1-(4-(5-(piperidin-1-yl)benzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C24H26N2O3
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1
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| 1 |
EC50 = 620 nM
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CP0441330
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N-butyl-3-methyl-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C19H20N4OS
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1
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| 1 |
EC50 = 630.96 nM
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CP0444665
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N-butyl-2-methoxy-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C19H20N4O2S
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1
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| 1 |
EC50 = 630.96 nM
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CP0492180
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4-chloro-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]-N-pentylbenzamide
Show/Hide
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C20H19ClFN3OS
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1
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| 1 |
EC50 = 630.96 nM
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CP0495236
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N-butyl-N-[5-[3-[(dimethylamino)methyl]phenyl]-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C23H25F3N4OS
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1
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| 1 |
EC50 = 630.96 nM
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CP0495239
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4-chloro-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]-N-propylbenzamide
Show/Hide
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C18H15ClFN3OS
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1
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| 1 |
EC50 = 630.96 nM
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CP0522413
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N-butyl-2-methyl-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C19H20N4OS
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1
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| 1 |
EC50 = 630.96 nM
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CP0446870
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-2,3-dimethylimidazole-4-sulfonamide
Show/Hide
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C17H20F3N5O2S
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1
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| 1 |
EC50 = 650 nM
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CP0425181
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1-(4-(5-butoxybenzofuran-2-yl)-3-methoxybenzyl)azetidine-3-carboxylic acid
Show/Hide
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C24H27NO5
|
1
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| 1 |
EC50 = 653 nM
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CP0504703
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4-chloro-N-[1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)ethyl]benzenesulfonamide
Show/Hide
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C13H17ClN4O2S
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1
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| 1 |
EC50 = 670 nM
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CP0382585
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1-[[3-fluoro-4-[5-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C24H20FN3O2S
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1
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| 1 |
EC50 = 680 nM
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CP0416499
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6-(hydroxymethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
Show/Hide
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C25H19F3N2O3
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1
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| 1 |
EC50 = 700 nM
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CP0523150
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4-chloro-N-[1-(4,5-diethyl-1,2-thiazol-3-yl)ethyl]benzenesulfonamide
Show/Hide
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C15H19ClN2O2S2
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1
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| 1 |
EC50 = 720 nM
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CP0512437
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1-(4-(7-Benzylimidazo[1,2-a]pyridin-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H22FN3O2
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1
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| 1 |
EC50 = 741 nM
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CP0489582
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N-butyl-3-chloro-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C18H17ClN4OS
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1
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| 1 |
EC50 = 794.33 nM
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CP0541335
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4-chloro-N-[(1R)-1-(7-chloro-1-ethylbenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
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C17H17Cl2N3O2S
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1
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| 1 |
EC50 = 800 nM
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CP0541340
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-5-methyl-1-propylpyrazole-4-sulfonamide
Show/Hide
|
C19H24F3N5O2S
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1
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| 1 |
EC50 = 800 nM
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CP0448174
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[4-[5-[2-chloro-5-fluoro-4-(2-hydroxyethoxy)phenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3,3-dimethylcyclobutyl)methanone
Show/Hide
|
C21H26ClFN4O4
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1
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| 1 |
EC50 = 910 nM
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CP0495238
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N-butyl-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C18H18N4OS
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1
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| 1 |
EC50 = 1000 nM
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CP0566917
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N-butyl-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide
Show/Hide
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C19H24FN3OS
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1
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| 1 |
EC50 = 1000 nM
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CP0551712
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-1,3-dimethylpyrazole-4-sulfonamide
Show/Hide
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C17H20F3N5O2S
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1
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| 1 |
EC50 = 1000 nM
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CP0398576
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4-chloro-N-[1-(4-methyl-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
Show/Hide
|
C20H21ClN4O2S2
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1
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| 1 |
EC50 = 1030 nM
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CP0242678
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1-methyl-4-oxo-N-[5-phenyl-4-(trifluoromethyl)pyridin-2-yl]quinoline-3-carboxamide
Show/Hide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 1100 nM
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CP0390010
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[4-[5-[2-chloro-5-fluoro-4-(3-hydroxypropoxy)phenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3,3-dimethylcyclobutyl)methanone
Show/Hide
|
C22H28ClFN4O4
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1
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| 1 |
EC50 = 1100 nM
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CP0411689
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[4-[5-[2-chloro-5-fluoro-4-[(2S)-2-hydroxypropoxy]phenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3,3-dimethylcyclobutyl)methanone
Show/Hide
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C22H28ClFN4O4
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1
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| 1 |
EC50 = 1100 nM
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CP0414072
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[4-[5-[2-chloro-4-[(2S)-2,3-dihydroxypropoxy]-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3,3-dimethylcyclobutyl)methanone
Show/Hide
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C22H28ClFN4O5
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1
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| 1 |
EC50 = 1100 nM
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CP0404171
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-5-methyl-1-propan-2-ylpyrazole-4-sulfonamide
Show/Hide
|
C19H24F3N5O2S
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1
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| 1 |
EC50 = 1100 nM
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CP0441117
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1-[[3-fluoro-4-[6-(piperidine-1-carbonyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C24H24FN3O3S
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1
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| 1 |
EC50 = 1170 nM
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CP0409609
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4-chloro-N-[1-(3-ethylimidazo[4,5-c]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
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C16H17ClN4O2S
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1
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| 1 |
EC50 = 1170 nM
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CP0414074
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[4-[5-[2-chloro-4-[(2R)-2,3-dihydroxypropoxy]-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3,3-dimethylcyclobutyl)methanone
Show/Hide
|
C22H28ClFN4O5
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1
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| 1 |
EC50 = 1200 nM
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CP0423750
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N-butyl-4-methoxy-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C19H20N4O2S
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1
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| 1 |
EC50 = 1258.93 nM
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CP0492175
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N-butyl-3-methoxy-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C19H20N4O2S
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1
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| 1 |
EC50 = 1258.93 nM
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CP0495234
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N-butyl-3-fluoro-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C18H17FN4OS
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1
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| 1 |
EC50 = 1258.93 nM
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CP0495235
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N-butyl-4-fluoro-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzamide
Show/Hide
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C18H17FN4OS
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1
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| 1 |
EC50 = 1258.93 nM
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CP0403668
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1-[[3-fluoro-4-[6-(pyridine-2-carbonyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C24H18FN3O3S
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1
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| 1 |
EC50 = 1300 nM
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CP0384331
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[4-[5-[4-[(2R)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclobutylmethanone
Show/Hide
|
C20H25ClFN5O4
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1
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| 1 |
EC50 = 1300 nM
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CP0412289
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1-(4-(6-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C24H20FN3O2S
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1
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| 1 |
EC50 = 1600 nM
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CP0448171
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[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-3,5-dichlorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclopentylmethanone
Show/Hide
|
C21H27Cl2N5O4
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1
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| 1 |
EC50 = 1600 nM
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CP0571501
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4-chloro-N-[1-(1,5-dimethylimidazol-2-yl)-2-phenylethyl]benzenesulfonamide
Show/Hide
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C19H20ClN3O2S
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1
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| 1 |
EC50 = 1610 nM
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CP0446866
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-4-(2-methylpropyl)benzenesulfonamide
Show/Hide
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C22H26F3N3O2S
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1
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| 1 |
EC50 = 1800 nM
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CP0513147
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]cyclopentanesulfonamide
Show/Hide
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C17H22F3N3O2S
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1
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| 1 |
EC50 = 1800 nM
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CP0398890
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1-(4-(6-Benzyl-2H-indazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H22FN3O2
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1
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| 1 |
EC50 = 1810 nM
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CP0494583
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4-chloro-N-[1-(4,5-dimethyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
Show/Hide
|
C18H19ClN4O2S
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1
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| 1 |
EC50 = 1830 nM
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CP0450420
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4-chloro-N-[(1R)-1-(1-ethyl-6-methylsulfonylbenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C18H20ClN3O4S2
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1
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| 1 |
EC50 = 1840 nM
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CP0392730
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1-[[3-fluoro-4-[6-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C24H20FN3O2S
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1
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| 1 |
EC50 = 1960 nM
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CP0489829
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1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinoline-8-carboxylic acid
Show/Hide
|
C25H17F3N2O4
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1
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| 1 |
EC50 = 2000 nM
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CP0393726
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1-(4-(5-benzylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C26H23NO3
|
1
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| 1 |
EC50 = 2070 nM
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CP0397743
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1-[[5-chloro-4-[3-[4-(cyclopentanecarbonyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl]-2-fluorophenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C23H27ClFN5O4
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1
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| 1 |
EC50 = 2100 nM
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CP0551713
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N-[5-[[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]sulfamoyl]-1,3-thiazol-2-yl]acetamide
Show/Hide
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C17H18F3N5O3S2
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1
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| 1 |
EC50 = 2200 nM
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CP0504700
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4-chloro-N-[1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)but-3-enyl]benzenesulfonamide
Show/Hide
|
C15H19ClN4O2S
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1
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| 1 |
EC50 = 2250 nM
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CP0477215
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1-(4-(6-butoxybenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
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C23H25NO4
|
1
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| 1 |
EC50 = 2290 nM
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CP0541336
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4-chloro-N-[1-(3-ethylimidazo[4,5-b]pyridin-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C16H17ClN4O2S
|
1
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| 1 |
EC50 = 2340 nM
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CP0457178
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1-[[3-fluoro-4-[5-(1-pyridin-2-ylethyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H22FN3O2S
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1
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| 1 |
EC50 = 2370 nM
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CP0387254
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4-chloro-N-[1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)-2-pyridin-3-ylethyl]benzenesulfonamide
Show/Hide
|
C18H20ClN5O2S
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1
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| 1 |
EC50 = 2370 nM
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CP0414077
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[4-[5-[4-[(2R)-2-amino-3-hydroxypropoxy]-2-chloro-5-fluorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3-chlorophenyl)methanone
Show/Hide
|
C22H22Cl2FN5O4
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1
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| 1 |
EC50 = 2400 nM
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CP0391739
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5-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]pentanoic acid
Show/Hide
|
C26H23FN2O2S
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1
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| 1 |
EC50 = 2410 nM
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CP0450614
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4-chloro-N-[(1R)-1-(1-ethyl-5-morpholin-4-ylbenzimidazol-2-yl)ethyl]benzenesulfonamide
Show/Hide
|
C21H25ClN4O3S
|
1
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| 1 |
EC50 = 2420 nM
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CP0380308
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1-(4-(5-butylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H25NO3
|
1
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| 1 |
EC50 = 2480 nM
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CP0423752
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N-butyl-N-[5-(1H-indol-6-yl)-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
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C22H19F3N4OS
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1
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| 1 |
EC50 = 2511.89 nM
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CP0504699
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4-chloro-N-[1-(5-methyl-4-propyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
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C20H23ClN4O2S
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1
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| 1 |
EC50 = 2690 nM
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CP0415217
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3-[5-chloro-4-[3-[4-(3,3-dimethylcyclobutanecarbonyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl]-2-fluorophenoxy]propanoic acid
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C22H26ClFN4O5
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1
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| 1 |
EC50 = 2700 nM
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CP0391835
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1-[[3-fluoro-4-[6-(1,3-thiazolidine-3-carbonyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
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C22H20FN3O3S2
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1
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| 1 |
EC50 = 2710 nM
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CP0392732
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1-[[4-[6-(azepane-1-carbonyl)-1,3-benzothiazol-2-yl]-3-fluorophenyl]methyl]azetidine-3-carboxylic acid
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C25H26FN3O3S
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1
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| 1 |
EC50 = 2720 nM
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CP0457208
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3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]benzoic acid
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C22H15FN2O2S
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1
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| 1 |
EC50 = 2820 nM
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CP0473335
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1-(4-(5-Benzyl-2H-indazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
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C25H22FN3O2
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1
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| 1 |
EC50 = 2890 nM
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CP0467473
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1-methyl-4-oxo-N-[6-phenyl-5-(trifluoromethyl)pyridin-3-yl]quinoline-3-carboxamide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 2900 nM
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CP0398580
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4-chloro-N-[1-(4,5-diethyl-1,2-oxazol-3-yl)ethyl]benzenesulfonamide
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C15H19ClN2O3S
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1
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| 1 |
EC50 = 3030 nM
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CP0398578
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4-chloro-N-[1-[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]-2-phenylethyl]benzenesulfonamide
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C18H16ClF3N4O2S
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1
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| 1 |
EC50 = 3170 nM
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CP0566693
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N-[1-(5-butyl-4-methyl-1,2,4-triazol-3-yl)-2-phenylethyl]-4-chlorobenzenesulfonamide
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C21H25ClN4O2S
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1
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| 1 |
EC50 = 3230 nM
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CP0537506
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1-[4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-2,2-dimethylbutan-1-one
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C19H26N4O3
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1
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| 1 |
EC50 = 3600 nM
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CP0389005
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1-(4-(6-benzylthiazolo[4,5-c]pyridin-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
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C24H20FN3O2S
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1
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| 1 |
EC50 = 3980 nM
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CP0520013
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N-butyl-N-[5-[3-(piperazin-1-ylmethyl)phenyl]-1,3,4-thiadiazol-2-yl]-4-(trifluoromethyl)benzamide
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C25H28F3N5OS
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1
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| 1 |
EC50 = 3981.07 nM
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CP0446869
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]-1,2-dimethylimidazole-4-sulfonamide
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C17H20F3N5O2S
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1
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| 1 |
EC50 = 4000 nM
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CP0136588
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1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]-1,5-naphthyridine-3-carboxamide
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C23H16F3N3O2
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1
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| 1 |
EC50 = 4100 nM
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CP0393723
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1-(4-(5-(pyridin-3-yl)benzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
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C24H20N2O3
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1
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| 1 |
EC50 = 5030 nM
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CP0457172
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3-[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]propanoic acid
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C24H19FN2O2S
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1
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| 1 |
EC50 = 5880 nM
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CP0504701
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4-chloro-N-[1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)butyl]benzenesulfonamide
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C15H21ClN4O2S
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1
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| 1 |
EC50 = 6190 nM
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CP0492178
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N-butyl-N-[(4-chlorophenyl)methyl]-5-pyridin-3-yl-1,3,4-thiadiazol-2-amine
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C18H19ClN4S
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1
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| 1 |
EC50 = 6309.57 nM
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CP0566694
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4-chloro-N-[1-(5-methyl-4-propan-2-yl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
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C20H23ClN4O2S
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1
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| 1 |
EC50 = 6340 nM
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CP0473337
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1-(4-(6-Benzylimidazo[1,2-a]pyridin-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
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C25H22FN3O2
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1
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| 1 |
EC50 = 6720 nM
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CP0504702
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4-chloro-N-[2-cyclopropyl-1-(4-ethyl-5-methyl-1,2,4-triazol-3-yl)ethyl]benzenesulfonamide
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C16H21ClN4O2S
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1
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| 1 |
EC50 = 7690 nM
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CP0450421
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]cyclopropanesulfonamide
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C15H18F3N3O2S
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1
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| 1 |
EC50 = 9000 nM
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CP0446867
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N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]pyridine-2-sulfonamide
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C17H17F3N4O2S
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1
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| 1 |
EC50 = 9200 nM
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CP0489580
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4-chloro-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]benzamide
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C15H9ClFN3OS
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1
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| 1 |
EC50 > 10000 nM
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CP0492176
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1-butyl-3-(4-chlorophenyl)-1-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)urea
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C18H18ClN5OS
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1
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| 1 |
EC50 > 10000 nM
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CP0492177
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N-butyl-4-chloro-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
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C17H17ClN4O2S2
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1
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| 1 |
EC50 > 10000 nM
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CP0520012
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4-chloro-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]-N-methylbenzamide
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C16H11ClFN3OS
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1
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| 1 |
EC50 > 10000 nM
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CP0414080
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[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-3,5-dichlorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-cyclohexylmethanone
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C22H29Cl2N5O4
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1
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| 1 |
EC50 > 10000 nM
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CP0508722
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(4R)-4-[[5-chloro-4-[3-[4-(3,3-dimethylcyclobutanecarbonyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl]-2-fluorophenoxy]methyl]-1,3-oxazolidin-2-one
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C23H27ClFN5O5
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1
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| 1 |
EC50 > 10000 nM
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CP0565525
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2-[5-chloro-4-[3-[4-(3,3-dimethylcyclobutanecarbonyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl]-2-fluorophenoxy]acetic acid
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C21H24ClFN4O5
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1
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| 1 |
EC50 > 10000 nM
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CP0431482
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N-[4-[[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]sulfamoyl]-2-methylphenyl]acetamide
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C21H23F3N4O3S
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1
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| 1 |
EC50 = 12400 nM
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CP0398579
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4-chloro-N-[1-(5-ethyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]benzenesulfonamide
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C18H18ClN3O3S
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1
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| 1 |
EC50 = 15200 nM
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CP0390590
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1-[[3-fluoro-4-[6-(pyrrolidine-1-carbonyl)-1,3-benzothiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid
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C23H22FN3O3S
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1
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| 1 |
EC50 > 20000 nM
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CP0419738
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4-chloro-N-[1-(4-methyl-1,2,4-triazol-3-yl)-2-phenylethyl]benzenesulfonamide
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C17H17ClN4O2S
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1
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| 1 |
EC50 = 22100 nM
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CP0574388
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4-chloro-N-[(1R)-1-[6-[(dimethylamino)methyl]-1-ethylbenzimidazol-2-yl]ethyl]benzenesulfonamide
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C20H25ClN4O2S
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1
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| 1 |
EC50 = 23500 nM
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CP0494585
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4-chloro-N-[(1S)-1-(4,5-diethyl-1,2,4-triazol-3-yl)ethyl]benzenesulfonamide
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C14H19ClN4O2S
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1
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| 1 |
EC50 > 33000 nM
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CP0388888
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N-[1-(4-benzyl-5-methyl-1,2,4-triazol-3-yl)-2-phenylethyl]-4-chlorobenzenesulfonamide
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C24H23ClN4O2S
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1
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| 1 |
EC50 > 100000 nM
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CP0504704
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4-chloro-N-[1-(2,3-dimethylimidazol-4-yl)-2-phenylethyl]benzenesulfonamide
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C19H20ClN3O2S
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1
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| 1 |
EC50 > 100000 nM
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CP0393727
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1-((2-(5-butoxybenzofuran-2-yl)thiazol-5-yl)methyl)azetidine-3-carboxylic acid
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C20H22N2O4S
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1
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| 1 |
EC50 > 1000 nM
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CP0520008
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4-chloro-N-ethyl-N-[5-(3-fluorophenyl)-1,3,4-thiadiazol-2-yl]benzamide
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C17H13ClFN3OS
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1
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| 1 |
EC50 > 3162.28 nM
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CP0508721
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[4-[5-[4-[(2S)-2-amino-3-hydroxypropoxy]-3,5-dichlorophenyl]-1,2,4-oxadiazol-3-yl]piperazin-1-yl]-(3-chlorophenyl)methanone
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C22H22Cl3N5O4
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1
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| 1 |
EC50 > 5400 nM
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CP0473336
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1-(4-(6-Benzyl-1H-benzo[d]imidazol-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
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C25H22FN3O2
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1
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| 1 |
EC50 > 6250 nM
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