Brief Information of the Compound and Protein
Compound Name
(4S)-4-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,3,4-thiadiazol-2-yl]phenoxy]pyrrolidin-2-one
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PubChem ID
CID: 127036240
Canonical SMILES
CC(C)Nc1cc(cc(C)n1)-c1nnc(s1)-c1cc(F)c(O[C@@H]2CNC(=O)C2)cc1Cl
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Compound Formula C21H21ClFN5O2S
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 560 nM
   TI
   LI
   LO
   TS