Brief Information of the Compound and Protein
Compound Name
(2R)-2-amino-3-[5-chloro-2-fluoro-4-[5-[2-methyl-6-(propan-2-ylamino)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]propan-1-ol
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PubChem ID
CID: 127029506
Canonical SMILES
CC(C)Nc1cc(cc(C)n1)-c1nc(no1)-c1cc(F)c(OC[C@H](N)CO)cc1Cl
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Compound Formula C20H23ClFN5O3
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 4 nM
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   LI
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