Brief Information of the Compound and Protein
Compound Name
1-methyl-4-oxo-N-[5-phenyl-6-(trifluoromethyl)pyridin-2-yl]-1,6-naphthyridine-3-carboxamide
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PubChem ID
CID: 56834955
SID: 134961654
Canonical SMILES
Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(n2)C(F)(F)F)c(=O)c2cnccc12
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Compound Formula C22H15F3N4O2
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 20 nM