Brief Information of the Compound and Protein
Compound Name
3-[[3-fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methyl-methylamino]propanoic acid
    Show/Hide
PubChem ID
CID: 57392609
Canonical SMILES
CN(CCC(O)=O)Cc1ccc(-c2nc3ccc(nc3s2)C2(CC2)c2ccccc2)c(F)c1
    Show/Hide
Compound Formula C26H24FN3O2S
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 196 nM
   TI
   LI
   LO
   TS