Protein Information

General Information of the Protein

Protein ID	PT00889
Protein Name	Estrogen receptor beta
Secondarily Protein Name	Nuclear receptor subfamily 3 group A member 2
Gene Name	ESR2
Secondarily Gene Name	ESTRB NR3A2
Sequence	MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Transcription factor > Nuclear receptor > Nuclear hormone receptor subfamily 3 > Nuclear hormone receptor subfamily 3 group A > Nuclear hormone receptor subfamily 3 group A member 2
Function	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Show/Hide
Uniprot ID	Primary ID: Q92731 Secondarily ID: A8K8K5 G3V5M5 O60608 O60685 O60702 O60703 O75583 O75584 Q0MWT5 Q0MWT6 Q86Z31 Q9UEV6 Q9UHD3 Q9UQK9 Show/Hide
Ensembl ID	ENSG00000140009
HGNC ID	HGNC:3468
Subcellular Location	Nucleus

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000168 , AH109A-TC

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0006292 Compound Info	(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol Show/Hide	C18H24O2	1
1	EC50 = 1.08 nM Bioactivity Info	TI LI LO TS
CP0332728 Compound Info	(7-hydroxynaphthalen-2-yl) 2-methylbenzenesulfonate Show/Hide	C17H14O4S	1
1	EC50 = 94 nM Bioactivity Info	TI LI LO TS
CP0383700 Compound Info	2-phenylethyl 4-hydroxybenzoate Show/Hide	C15H14O3	1
1	EC50 = 123 nM Bioactivity Info	TI LI LO TS
CP0497658 Compound Info	(5-hydroxynaphthalen-1-yl) 2-chlorobenzoate Show/Hide	C17H11ClO3	1
1	EC50 = 185 nM Bioactivity Info	TI LI LO TS
CP0424173 Compound Info	(5-hydroxynaphthalen-1-yl) 2-methylbenzenesulfonate Show/Hide	C17H14O4S	1
1	EC50 = 229 nM Bioactivity Info	TI LI LO TS
CP0327912 Compound Info	(7-hydroxynaphthalen-2-yl) 2-chlorobenzoate Show/Hide	C17H11ClO3	1
1	EC50 = 485 nM Bioactivity Info	TI LI LO TS
CP0383701 Compound Info	(5-hydroxynaphthalen-1-yl) cyclohexanecarboxylate Show/Hide	C17H18O3	1
1	EC50 = 823 nM Bioactivity Info	TI LI LO TS
CP0410723 Compound Info	(5-hydroxynaphthalen-1-yl) 4-methylbenzenesulfonate Show/Hide	C17H14O4S	1
1	EC50 = 1010 nM Bioactivity Info	TI LI LO TS
CP0235327 Compound Info	(5-hydroxynaphthalen-1-yl) benzoate Show/Hide	C17H12O3	1
1	EC50 = 1460 nM Bioactivity Info	TI LI LO TS
CP0410725 Compound Info	phenacyl 3,4-dihydroxybenzoate Show/Hide	C15H12O5	1
1	EC50 = 1930 nM Bioactivity Info	TI LI LO TS
CP0415718 Compound Info	(5-hydroxynaphthalen-1-yl) 2-methoxybenzoate Show/Hide	C18H14O4	1
1	EC50 = 1980 nM Bioactivity Info	TI LI LO TS
CP0693187 Compound Info	5-hydroxynaphthalen-1-yl 2-methylbenzoate Show/Hide	C18H14O3	1
1	EC50 = 2690 nM Bioactivity Info	TI LI LO TS
CP0410722 Compound Info	(7-hydroxynaphthalen-2-yl) 2-fluorobenzoate Show/Hide	C17H11FO3	1
1	EC50 = 4950 nM Bioactivity Info	TI LI LO TS
CP0415719 Compound Info	(3-hydroxyphenyl) 3-fluorobenzoate Show/Hide	C13H9FO3	1
1	EC50 = 8590 nM Bioactivity Info	TI LI LO TS
CP0410797 Compound Info	(3-hydroxyphenyl) 3-methoxybenzoate Show/Hide	C14H12O4	1
1	EC50 = 13400 nM Bioactivity Info	TI LI LO TS
CP0410724 Compound Info	2-benzoyloxy-4-hydroxybenzoic acid Show/Hide	C14H10O5	1
1	EC50 = 19000 nM Bioactivity Info	TI LI LO TS
CP0400790 Compound Info	[2-(4-methoxyphenyl)-2-oxoethyl] 4-hydroxybenzoate Show/Hide	C16H14O5	1
1	EC50 = 28900 nM Bioactivity Info	TI LI LO TS
CP0400773 Compound Info	benzhydryl 4-hydroxybenzoate Show/Hide	C20H16O3	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0526857 Compound Info	(7-hydroxynaphthalen-2-yl) 2-ethoxybenzoate Show/Hide	C19H16O4	1
1	IC50 = 1310 nM Bioactivity Info	TI LI LO TS
CP0003923 Compound Info	(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine Show/Hide	C26H29NO	1
1	IC50 = 1660 nM Bioactivity Info	TI LI LO TS
CP0844724 Compound Info	5-hydroxynaphthalen-1-yl 3-methylbenzoate Show/Hide	C18H14O3	1
1	IC50 = 2820 nM Bioactivity Info	TI LI LO TS
CP0416291 Compound Info	(5-hydroxynaphthalen-1-yl) 4-bromobenzoate Show/Hide	C17H11BrO3	1
1	IC50 = 4350 nM Bioactivity Info	TI LI LO TS
CP0432430 Compound Info	(5-hydroxynaphthalen-1-yl) (E)-3-phenylprop-2-enoate Show/Hide	C19H14O3	1
1	IC50 = 8940 nM Bioactivity Info	TI LI LO TS
CP0169364 Compound Info	(7-hydroxynaphthalen-2-yl) 2-methoxybenzoate Show/Hide	C18H14O4	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS
CP0432432 Compound Info	(7-hydroxynaphthalen-2-yl) 3-methylbenzoate Show/Hide	C18H14O3	1
1	IC50 > 100000 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000023 , BTI-Tn-5B1-4

Cell Line Info

Cell Line ID: CL000026 , CHO-K1

Cell Line Info

Cell Line ID: CL000109 , COS-1

Cell Line Info

Cell Line ID: CL000053 , COS-7

Cell Line Info

Cell Line ID: CL000044 , CV-1

Cell Line Info

Cell Line ID: CL000759 , GeneBLAzer ERbeta-UAS-bla GripTite 293

Cell Line Info

Cell Line ID: CL000209 , HEC-1

Cell Line Info

Cell Line ID: CL000025 , HEK-293T

Cell Line Info

Cell Line ID: CL000006 , HEK293

Cell Line Info

Cell Line ID: CL001042 , HEK293/Gal4

Cell Line Info

Cell Line ID: CL000017 , HeLa

Cell Line Info

Cell Line ID: CL000063 , Hep-G2

Cell Line Info

Cell Line ID: CL000111 , MDA-MB-231

Cell Line Info

Cell Line ID: CL000013 , Sf9

Cell Line Info

Cell Line ID: CL000004 , SH-SY5Y

Cell Line Info

Cell Line ID: CL000078 , T-47D

Cell Line Info

Cell Line ID: CL000043 , U2OS

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0006292 Compound Info	(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol Show/Hide	C18H24O2	37
1	EC50 = 0.02 nM
2	EC50 = 0.03 nM
3	EC50 = 0.039 nM
4	EC50 = 0.151 nM
5	EC50 = 0.21 nM
6	EC50 = 0.25 nM
7	EC50 = 1.05 nM
8	EC50 = 5.6 nM
9	EC50 = 24 nM
10	IC50 = 0.3 nM
11	IC50 = 0.89 nM
12	IC50 = 1 nM
13	IC50 = 1.02 nM
14	IC50 = 1.1 nM
15	IC50 = 1.2 nM
16	IC50 = 1.4 nM
17	IC50 = 1.9 nM
18	IC50 = 2 nM
19	IC50 = 2.79 nM
20	IC50 = 2.9 nM
21	IC50 = 3 nM
22	IC50 = 3.2 nM
23	IC50 = 3.6 nM
24	IC50 = 4 nM
25	IC50 = 5.6 nM
26	IC50 = 11 nM
27	IC50 = 11.35 nM
28	IC50 = 16.7 nM
29	IC50 = 19 nM
30	IC50 = 24 nM
31	Ka = 0.5 nM
32	Kd = 0.5 nM
33	Kd = 4.12 nM
34	Ki = 2 nM
35	Ki = 3.162 nM
36	Ki = 3.5 nM
37	Ki = 100 nM
CP0044042 Compound Info	(1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one Show/Hide	C18H22O2	5
1	EC50 = 0.94 nM
2	EC50 = 8 nM
3	EC50 = 1135 nM
4	IC50 = 31 nM
5	IC50 = 540 nM
CP0062960 Compound Info	(+/-)-2,3-bis(4-hydroxyphenyl)propanenitrile Show/Hide	C15H13NO2	2
1	EC50 = 1.9 nM
2	EC50 = 6 nM
CP0012708 Compound Info	5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one Show/Hide	C15H10O5	15
1	EC50 = 6 nM
2	EC50 = 200 nM
3	IC50 = 4 nM
4	IC50 = 6.8 nM
5	IC50 = 9.7 nM
6	IC50 = 10 nM
7	IC50 = 18 nM
8	IC50 = 25 nM
9	IC50 = 61 nM
10	IC50 = 83 nM
11	IC50 = 98.7 nM
12	IC50 = 390 nM
13	IC50 = 395 nM
14	IC50 = 45900 nM
15	Ki = 24 nM
CP0042711 Compound Info	4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol Show/Hide	C18H20O2	3
1	EC50 = 9 nM
2	IC50 = 4 nM
3	Ki = 0.63 nM
CP0141053 Compound Info	2-(4-hydroxyphenyl)-1-benzothiophen-6-ol Show/Hide	C14H10O2S	2
1	EC50 = 114 nM
2	Ki = 2.3 nM
CP0334570 Compound Info	2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophen-6-ol Show/Hide	C14H9FO2S	1
1	EC50 = 115 nM
CP0214394 Compound Info	2-(4-hydroxy-2-methylphenyl)-1-benzothiophen-6-ol Show/Hide	C15H12O2S	1
1	EC50 = 129 nM
CP0203601 Compound Info	4-(6-hydroxy-1-benzothiophen-2-yl)benzene-1,2-diol Show/Hide	C14H10O3S	1
1	EC50 = 249 nM
CP0041761 Compound Info	2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol Show/Hide	C28H27NO4S	16
1	EC50 = 260 nM
2	IC50 = 1.6 nM
3	IC50 = 1.9 nM
4	IC50 = 8.2 nM
5	IC50 = 12 nM
6	IC50 = 18.9 nM
7	IC50 = 43 nM
8	IC50 = 470 nM
9	IC50 = 557 nM
10	IC50 = 1420 nM
11	IC50 = 7430 nM
12	Ka = 41.24 nM
13	Ki = 2.74 nM
14	Ki = 4.3 nM
15	Ki = 10 nM
16	Ki = 23 nM
CP0040010 Compound Info	2-(3-hydroxyphenyl)-1-benzothiophen-6-ol Show/Hide	C14H10O2S	1
1	EC50 = 740 nM
CP0070388 Compound Info	Bisphenol A (BPA) Show/Hide	C15H16O2	1
1	EC50 = 1100 nM
CP0063761 Compound Info	(1S,10R,11S,14R,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol Show/Hide	C18H24O2	1
1	EC50 = 1230 nM
CP0003923 Compound Info	(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine Show/Hide	C26H29NO	7
1	EC50 = 1660 nM
2	IC50 = 170 nM
3	IC50 = 180 nM
4	IC50 = 188 nM
5	IC50 = 190 nM
6	IC50 > 1000 nM
7	Ki = 0.51 nM
CP0203623 Compound Info	2-(4-hydroxy-3-methylphenyl)-1-benzothiophen-6-ol Show/Hide	C15H12O2S	1
1	EC50 = 1830 nM
CP0148181 Compound Info	2-(4-hydroxy-3-propylphenyl)-1-benzothiophen-6-ol Show/Hide	C17H16O2S	1
1	EC50 = 3940 nM
CP0228049 Compound Info	2-phenyl-1-benzothiophen-6-ol Show/Hide	C14H10OS	1
1	EC50 = 4310 nM
CP0210429 Compound Info	2-(3-ethyl-4-hydroxyphenyl)-1-benzothiophen-6-ol Show/Hide	C16H14O2S	1
1	EC50 = 4710 nM
CP0214393 Compound Info	2-(3-fluoro-4-hydroxyphenyl)-1-benzothiophene-4,6-diol Show/Hide	C14H9FO3S	1
1	EC50 = 7470 nM
CP0178147 Compound Info	1-[2-hydroxy-5-(6-hydroxy-1-benzothiophen-2-yl)phenyl]ethan-1-one Show/Hide	C16H12O3S	1
1	EC50 > 10000 nM
CP0185029 Compound Info	2-(4-methylphenyl)-1-benzothiophen-6-ol Show/Hide	C15H12OS	1
1	EC50 > 10000 nM
CP0257596 Compound Info	2-(4-hydroxy-3-methylphenyl)-1-benzothiophene-4,6-diol Show/Hide	C15H12O3S	1
1	EC50 > 10000 nM
CP0319942 Compound Info	(S)-9a-ethyl-1-fluoro-6-(trifluoromethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C17H14F4N2O	1
1	IC50 = 0.3 nM
CP0950473 Compound Info	N-[4-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)butyl]-8-(4-oxo-2-thioxodihydroquinazolin-3-yl)octanamide Show/Hide	C45H50N4O4S	2
1	IC50 = 0.82 nM
2	IC50 = 28.34 nM
CP0041780 Compound Info	9a-butyl-7-hydroxy-4-phenyl-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C23H24O2	1
1	IC50 = 1.2 nM
CP0238687 Compound Info	4-[4-[8-fluoro-4-(4-hydroxyphenyl)-2,3-dihydro-1-benzoxepin-5-yl]phenoxy]butanoic acid Show/Hide	C26H23FO5	1
1	IC50 = 1.23 nM
CP0186256 Compound Info	9a-butyl-7-hydroxy-4-iodo-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C17H19IO2	1
1	IC50 = 1.3 nM
CP0202515 Compound Info	(S)-9a-ethyl-6-phenyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C22H20N2O	1
1	IC50 = 1.4 nM
CP0045382 Compound Info	9a-butyl-7-hydroxy-4-(trifluoromethyl)-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C18H19F3O2	1
1	IC50 = 1.5 nM
CP0100289 Compound Info	9a-butyl-7-hydroxy-4-propyl-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C20H26O2	1
1	IC50 = 1.5 nM
CP0202518 Compound Info	(R)-9a-ethyl-6-(trifluoromethyl)-9,9a-dihydroindeno[2,1-e]indazole-7,10(3H,8H)-dione Show/Hide	C17H13F3N2O2	1
1	IC50 = 1.5 nM
CP0449391 Compound Info	9a-butyl-7-hydroxy-4-(thiophen-2-yl)-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C21H22O2S	1
1	IC50 = 1.6 nM
CP0045468 Compound Info	6-bromo-9a-ethyl-1-fluoro-2,8,9,10-tetrahydroindeno[2,1-e]indazol-7-one Show/Hide	C16H14BrFN2O	1
1	IC50 = 1.6 nM
CP0045475 Compound Info	(S)-6-bromo-9a-(2-cyclopropyl-ethyl)-8,9,9a,10-tetrahydro-3H-2,3-diaza-cyclopenta[a]fluoren-7-one Show/Hide	C19H19BrN2O	1
1	IC50 = 1.6 nM
CP0240380 Compound Info	4-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol Show/Hide	C26H29NO2	1
1	IC50 = 1.68 nM
CP0045086 Compound Info	4-Hydroxytamoxifen Show/Hide	C26H29NO2	1
1	IC50 = 1.68 nM
CP0255385 Compound Info	(R,S)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C17H19BrO2	1
1	IC50 = 1.8 nM
CP0040732 Compound Info	(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol Show/Hide	C28H31NO2	1
1	IC50 = 1.8 nM
CP0081581 Compound Info	(+/-)-6-bromo-9a-butyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C17H18BrN3O	1
1	IC50 = 1.8 nM
CP0960446 Compound Info	N-(2-(3-(5-Hydroxy-1H-benzo(d)imidazol-2-yl)-propanamido)ethyl)-3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamide Show/Hide	C37H36N4O4	1
1	IC50 = 1.99 nM
CP0140839 Compound Info	(S)-6-bromo-9a-ethyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C16H15BrN2O	1
1	IC50 = 2.2 nM
CP0199435 Compound Info	(S)(-)-9a-butyl-6-thiophen-2-yl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C21H21N3OS	1
1	IC50 = 2.3 nM
CP0283276 Compound Info	(S)-9a-ethyl-6-(trifluoromethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C17H15F3N2O	1
1	IC50 = 2.8 nM
CP0770059 Compound Info	N-(4-(3-(5-Hydroxy-1H-benzo(d)imidazol-2-yl)-propanamido)butyl)-3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamide Show/Hide	C39H40N4O4	1
1	IC50 = 2.84 nM
CP0040596 Compound Info	(E)-3-[4-[(E)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoic acid Show/Hide	C25H22O3	3
1	IC50 = 3 nM
2	IC50 = 3.77 nM
3	Ki = 10 nM
CP0835412 Compound Info	3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(3-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)propyl)acrylamide Show/Hide	C39H40N4O4	1
1	IC50 = 3.01 nM
CP0171086 Compound Info	9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C21H22O3	1
1	IC50 = 3.1 nM
CP0081583 Compound Info	(S)-9a-butyl-6-trifluoromethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C18H18F3N3O	1
1	IC50 = 3.2 nM
CP0690577 Compound Info	(E)-3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylic acid Show/Hide	C25H22O3	2
1	IC50 = 3.77 nM
2	IC50 = 6.8 nM
CP0833945 Compound Info	N-[3-(3-(5-Hydroxy-1H-benzo[d]imidazol-2-yl)-propanamido)propyl]-3-[4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl]acrylamide Show/Hide	C38H38N4O4	1
1	IC50 = 3.78 nM
CP0835419 Compound Info	(E)-N-[5-(3-(5-Hydroxy-1H-benzo[d]imidazol-2-yl)-propanamido)pentyl]-3-[4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl]acrylamide Show/Hide	C40H42N4O4	2
1	IC50 = 3.81 nM
2	IC50 = 63.97 nM
CP0210114 Compound Info	6,9a-diethyl-3,8,9,10-tetrahydroindeno[2,1-e]indazol-7-one Show/Hide	C18H20N2O	1
1	IC50 = 4 nM
CP0317701 Compound Info	(E)-N-(2-aminoethyl)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enamide;2,2,2-trifluoroacetic acid Show/Hide	C33H31F9N2O8	1
1	IC50 = 4.26 nM
CP0037879 Compound Info	(2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OL Show/Hide	C27H29NO4S	4
1	IC50 = 4.5 nM
2	IC50 = 43 nM
3	IC50 = 45 nM
4	IC50 = 143 nM
CP0776597 Compound Info	3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(2-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)ethyl)acrylamide Show/Hide	C38H38N4O4	1
1	IC50 = 4.88 nM
CP0053310 Compound Info	(S)(-)-9a-Butyl-6-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C19H23N3O	1
1	IC50 = 5.1 nM
CP0221081 Compound Info	3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-benzo[1,4]oxathiin-6-ol Show/Hide	C27H27NO4S	1
1	IC50 = 5.1 nM
CP0835418 Compound Info	3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(6-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)hexyl)acrylamide Show/Hide	C42H46N4O4	1
1	IC50 = 5.22 nM
CP0835416 Compound Info	3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(4-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)butyl)acrylamide Show/Hide	C40H42N4O4	1
1	IC50 = 5.26 nM
CP0277073 Compound Info	9a-butyl-4-chloro-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C17H19ClO2	1
1	IC50 = 5.3 nM
CP0276513 Compound Info	(S)(-)-6-bromo-9a-butyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C17H18BrN3O	1
1	IC50 = 5.7 nM
CP0292056 Compound Info	(S)(-)-6,9a-diethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C17H19N3O	1
1	IC50 = 5.7 nM
CP0943750 Compound Info	N-(3-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)propyl)-4-(4-(8-(4-oxo-2-thioxodihydroquinazolin-3-yl)octanoyl)piperazin-1-yl)benzamide Show/Hide	C55H60N6O5S	1
1	IC50 = 6.81 nM
CP0043589 Compound Info	(13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C32H47F5O3S	6
1	IC50 = 7 nM
2	IC50 = 8.4 nM
3	IC50 = 10.2 nM
4	IC50 = 21 nM
5	IC50 = 44.1 nM
6	Ki = 1.39 nM
CP0045471 Compound Info	(S)-9a-ethyl-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C17H18N2O	1
1	IC50 = 7.2 nM
CP0292053 Compound Info	9a-butyl-6-furan-2-yl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C21H21N3O2	1
1	IC50 = 7.4 nM
CP0041801 Compound Info	(S)-6-cyclopropyl-9a-ethyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C19H20N2O	1
1	IC50 = 7.7 nM
CP0210116 Compound Info	(S)-6-chloro-9a-ethyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C16H15ClN2O	1
1	IC50 = 7.7 nM
CP0944381 Compound Info	(E/Z)-N-[6-(3-(5-Hydroxy-1H-benzo[d]imidazol-2-yl)-propanamido)hexyl]-3-[4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl]acrylamide Show/Hide	C41H44N4O4	1
1	IC50 = 7.8 nM
CP0833947 Compound Info	3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(5-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)pentyl)acrylamide Show/Hide	C41H44N4O4	2
1	IC50 = 7.84 nM
2	IC50 = 154.4 nM
CP0140759 Compound Info	6-bromo-9a-ethyl-8,9-dihydro-3H-indeno[2,3-e]indazole-7,10-dione Show/Hide	C16H13BrN2O2	1
1	IC50 = 8 nM
CP0124464 Compound Info	(2R,3S)-5-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C27H28ClNO4S	1
1	IC50 = 8 nM
CP0201714 Compound Info	(8R,9S,10S,13S,14S,17S)-3,13-dimethyl-10-vinyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C21H30O	1
1	IC50 = 9 nM
CP0201712 Compound Info	(8R,9S,10R,13S,14S,17S)-3,10,13-trimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C20H30O	1
1	IC50 = 9.4 nM
CP0034676 Compound Info	(3beta,17beta)-androst-5-ene-3,17-diol Show/Hide	C19H30O2	2
1	IC50 = 9.9 nM
2	IC50 = 10 nM
CP0144412 Compound Info	(3S,8R,9S,10S,13S,14S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H30O2	1
1	IC50 = 11 nM
CP0064239 Compound Info	(S)(-)-9a-Ethyl-6-trifluoromethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C16H14F3N3O	1
1	IC50 = 11 nM
CP0199436 Compound Info	9a-ethyl-6-propyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C18H21N3O	1
1	IC50 = 11 nM
CP0339643 Compound Info	9a-ethyl-6-(4-hydroxy-phenyl)-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C21H19N3O2	1
1	IC50 = 11 nM
CP0173429 Compound Info	(3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H30O2	1
1	IC50 = 11 nM
CP0835404 Compound Info	N-(3-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)propyl)-4-(4-oxo-2-thioxodihydroquinazolin-3-yl)butanamide Show/Hide	C40H40N4O4S	1
1	IC50 = 12.6 nM
CP0348297 Compound Info	9a-butyl-4-ethyl-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C19H24O2	1
1	IC50 = 13 nM
CP0183723 Compound Info	(2R,3S)-5-Fluoro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C27H28FNO4S	1
1	IC50 = 13 nM
CP0110689 Compound Info	(2R,3S)-5-Fluoro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H28FNO4S	1
1	IC50 = 13.2 nM
CP0216189 Compound Info	(3S,8R,9S,10S,13S,14S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C22H30O2	1
1	IC50 = 14 nM
CP0193742 Compound Info	(2R,3S)-5-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H28ClNO4S	1
1	IC50 = 14 nM
CP0154891 Compound Info	(3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C22H30O2	1
1	IC50 = 14 nM
CP0276893 Compound Info	4,9a-dibutyl-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C21H28O2	1
1	IC50 = 15 nM
CP0240381 Compound Info	(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[5-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]pentyl]prop-2-enamide Show/Hide	C55H54N2O4	1
1	IC50 = 15.5 nM
CP0317700 Compound Info	(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[4-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]butyl]prop-2-enamide Show/Hide	C48H52N2O4	1
1	IC50 = 15.7 nM
CP0100299 Compound Info	(R,S)-9a-butyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydrofluoren-3-one Show/Hide	C18H22O2	1
1	IC50 = 16 nM
CP0192119 Compound Info	(3S,8R,9S,10S,13S,14S,17S,Z)-13-methyl-10-(prop-1-enyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 16 nM
CP0173431 Compound Info	(3S,10S,13S,17S,Z)-13-methyl-10-(prop-1-enyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 16 nM
CP0034677 Compound Info	(3S,10S,13S,17S)-10-ethynyl-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H28O2	1
1	IC50 = 17 nM
CP0557200 Compound Info	(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[5-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]pentyl]prop-2-enamide Show/Hide	C49H54N2O4	1
1	IC50 = 17.5 nM
CP0053311 Compound Info	6-ethyl-9a-propyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C18H21N3O	1
1	IC50 = 18 nM
CP0282785 Compound Info	6,9a-diethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C17H19N3O	1
1	IC50 = 18 nM
CP0960445 Compound Info	N-[3-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)propyl]-4-[4-(4-(4-oxo-2-thioxodihydroquinazolin-3-yl)butanoyl)piperazin-1-yl]benzamide Show/Hide	C51H52N6O5S	1
1	IC50 = 18.5 nM
CP0648741 Compound Info	4-Hydroxytamoxifen Show/Hide	C26H29NO2	8
1	IC50 = 21 nM
2	IC50 = 26.1 nM
3	IC50 = 32 nM
4	IC50 = 100 nM
5	Ki = 0.16 nM
6	Ki = 0.5 nM
7	Ki = 1.7 nM
8	Ki = 3.162 nM
CP0171381 Compound Info	(3S,10R,13S,17S,E)-10-(2-fluorovinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H29FO2	1
1	IC50 = 22 nM
CP0363564 Compound Info	(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[3-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]propyl]prop-2-enamide Show/Hide	C53H50N2O4	1
1	IC50 = 22.2 nM
CP0167086 Compound Info	3-arylquinazolinone, 1aar Show/Hide	C15H12N2O4	1
1	IC50 = 24 nM
CP0100312 Compound Info	9a-ethyl-6-methyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C16H17N3O	1
1	IC50 = 24 nM
CP0216190 Compound Info	(3S,8R,9S,10S,13S,14S,17S)-13,17-dimethyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 25 nM
CP0034680 Compound Info	(3S,10R,13S,17S,Z)-10-(2-fluorovinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H29FO2	1
1	IC50 = 25 nM
CP0250451 Compound Info	(3S,10S,13S,17S)-13,17-dimethyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 25 nM
CP0100310 Compound Info	9a-butyl-6-methyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C18H21N3O	1
1	IC50 = 27 nM
CP0240379 Compound Info	(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[2-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]ethyl]prop-2-enamide Show/Hide	C46H48N2O4	1
1	IC50 = 27.5 nM
CP0216658 Compound Info	(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C20H30O	1
1	IC50 = 34 nM
CP0240378 Compound Info	(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[3-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]propyl]prop-2-enamide Show/Hide	C47H50N2O4	1
1	IC50 = 34 nM
CP0206457 Compound Info	(2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C26H27NO4S	2
1	IC50 = 37 nM
2	IC50 = 38 nM
CP0192524 Compound Info	9a-butyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fluorene-4-carbonitrile Show/Hide	C18H19NO2	1
1	IC50 = 38 nM
CP0064240 Compound Info	6-butyl-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C19H23N3O	1
1	IC50 = 43 nM
CP0074680 Compound Info	6-bromo-9a-propyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C16H16BrN3O	1
1	IC50 = 43 nM
CP0264515 Compound Info	(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[4-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]butyl]prop-2-enamide Show/Hide	C54H52N2O4	1
1	IC50 = 44 nM
CP0149907 Compound Info	(2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C27H29NO4S	2
1	IC50 = 44.4 nM
2	IC50 = 45 nM
CP0154157 Compound Info	(2R,3S)-3-(4-Hydroxy-phenyl)-5-methyl-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C28H31NO4S	1
1	IC50 = 46.2 nM
CP0342151 Compound Info	3-arylquinazolinethione, 1ba Show/Hide	C14H10N2O3S	1
1	IC50 = 47 nM
CP0264220 Compound Info	(1R,2S,5S,6S,9S,10R,14R,15S)-5-methylpentacyclo[12.3.2.0^{1,13}.0^{2,10}.0^{5,9}]nonadec-12-ene-6,15-diol Show/Hide	C20H30O2	1
1	IC50 = 50 nM
CP0172476 Compound Info	(8R,9S,10S,13S,14S,17S)-3,13,17-trimethyl-10-vinyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C22H32O	1
1	IC50 = 53 nM
CP0272678 Compound Info	(2R,3S)-3-(4-Hydroxy-phenyl)-8-methyl-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C28H31NO4S	1
1	IC50 = 54 nM
CP0339642 Compound Info	9a-butyl-6-propyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C20H25N3O	1
1	IC50 = 58 nM
CP0292054 Compound Info	6-bromo-9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C15H14BrN3O	1
1	IC50 = 60 nM
CP0201715 Compound Info	(8R,9S,10S,13S,14S,17S)-3-chloro-13-methyl-10-vinyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C20H27ClO	1
1	IC50 = 64 nM
CP0124500 Compound Info	3-(4-Fluoro-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H28FNO3S	1
1	IC50 = 66.6 nM
CP0240382 Compound Info	(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[2-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]ethyl]prop-2-enamide Show/Hide	C52H48N2O4	1
1	IC50 = 67.7 nM
CP0160806 Compound Info	(8R,9S,10S,13S,14S,17S)-17-ethynyl-3,13-dimethyl-10-vinyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C23H30O	1
1	IC50 = 72 nM
CP0192855 Compound Info	(2R,3S)-7-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H28ClNO4S	1
1	IC50 = 73 nM
CP0046577 Compound Info	(8R,9S,13S,14S,17S)-17-(1,3-dihydro-2-benzofuran-5-yl)-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C26H30O3	1
1	IC50 = 76.38 nM
CP0109775 Compound Info	3-arylquinazolinethione, 1bd Show/Hide	C15H12N2O2S	1
1	IC50 = 79 nM
CP0319752 Compound Info	6-methyl-9a-propyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C17H19N3O	1
1	IC50 = 81 nM
CP0237525 Compound Info	(3S,10R,13S,17S,Z)-10-(2-chlorovinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H29ClO2	1
1	IC50 = 83 nM
CP0034671 Compound Info	(3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 96 nM
CP0074985 Compound Info	3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazoline-4-thione Show/Hide	C14H9FN2O3S	1
1	IC50 = 102 nM
CP0214273 Compound Info	(2S,3R)-2-[4-(2-Cycloheptylamino-ethoxy)-phenyl]-3-(3-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C29H33NO4S	1
1	IC50 = 103 nM
CP0168414 Compound Info	(2R,3S)-8-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H28ClNO4S	1
1	IC50 = 105.4 nM
CP0287113 Compound Info	(2S,3R)-3-(3-Hydroxy-phenyl)-2-{4-[2-(4-methyl-piperidin-1-yl)-ethoxy]-phenyl}-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C28H31NO4S	1
1	IC50 = 109 nM
CP0169729 Compound Info	(8R,9S,10S,13S,14S,17S)-3-ethyl-13-methyl-10-vinyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C22H32O	1
1	IC50 = 115 nM
CP0111013 Compound Info	(2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H29NO4S	1
1	IC50 = 115 nM
CP0216187 Compound Info	(8R,9S,10S,13S,14S,17S)-13-methyl-3-methylene-10-vinyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C21H30O	1
1	IC50 = 120 nM
CP0034683 Compound Info	(3S,10R,13S,17S,E)-10-(2-chlorovinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H29ClO2	1
1	IC50 = 122 nM
CP0215938 Compound Info	(3S,10S,13S,17S)-10-allyl-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 128 nM
CP0193743 Compound Info	(2S,3R)-2-[4-(2-Dimethylamino-ethoxy)-phenyl]-3-(3-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C24H25NO4S	1
1	IC50 = 129 nM
CP0712266 Compound Info	[(+/-)-cis] 3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H29NO4S	1
1	IC50 = 143 nM
CP0154961 Compound Info	3-arylquinazolinethione, 1be Show/Hide	C16H14N2O2S	1
1	IC50 = 156 nM
CP0177061 Compound Info	(1S,2S,5S,6S,9S,10R,14R,15S)-5-methylpentacyclo[12.3.3.0^{1,13}.0^{2,10}.0^{5,9}]icosa-12,18-diene-6,15-diol Show/Hide	C21H30O2	1
1	IC50 = 157 nM
CP0134920 Compound Info	2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol Show/Hide	C27H30N2O2	4
1	IC50 = 165.96 nM
2	IC50 = 166 nM
3	IC50 = 291 nM
4	IC50 = 291.07 nM
CP0095067 Compound Info	3-arylquinazolinone, 1aa Show/Hide	C14H10N2O4	1
1	IC50 = 179 nM
CP0192974 Compound Info	(2R,3S)-5-Ethyl-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C29H33NO4S	1
1	IC50 = 185 nM
CP0041803 Compound Info	methyl 9a-ethyl-7-oxo-3,8,9,10-tetrahydroindeno[2,1-e]indazole-6-carboxylate Show/Hide	C18H18N2O3	1
1	IC50 = 207 nM
CP0215939 Compound Info	(3S,10R,13S,17S,E)-10-(2-bromovinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H29BrO2	1
1	IC50 = 210 nM
CP0034674 Compound Info	(3S,10R,13S,17S,Z)-10-(2-bromovinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C20H29BrO2	1
1	IC50 = 212 nM
CP0250450 Compound Info	(3S,10S,13S,17S)-3,17-dihydroxy-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde Show/Hide	C19H28O3	1
1	IC50 = 230 nM
CP0053312 Compound Info	(R)(+)--9a-butyl-6-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C19H23N3O	1
1	IC50 = 242 nM
CP0154128 Compound Info	3-(3-Hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C27H29NO4S	1
1	IC50 = 250 nM
CP0726678 Compound Info	17alpha-(2,2-Diacetyl-1,3-dihydro-2H-inden-5-yl)-estradiol Show/Hide	C31H36O4	1
1	IC50 = 253.51 nM
CP0160833 Compound Info	(3S,8R,9S,10S,13S,14S,17S)-3,13-dimethyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 255 nM
CP0133181 Compound Info	3-(2-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one Show/Hide	C14H9FN2O4	1
1	IC50 = 256 nM
CP0205233 Compound Info	3-(2-chloro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one Show/Hide	C14H9ClN2O4	1
1	IC50 = 263 nM
CP0274861 Compound Info	3-arylquinazolinone, 1aan Show/Hide	C16H14N2O3	1
1	IC50 = 265 nM
CP0172726 Compound Info	(3S,10S,13S,17S)-13-methyl-10-(prop-2-ynyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H30O2	1
1	IC50 = 286 nM
CP0050678 Compound Info	2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol Show/Hide	C28H32N2O2	4
1	IC50 = 289 nM
2	IC50 = 289.07 nM
3	IC50 = 345.94 nM
4	IC50 = 346 nM
CP0034679 Compound Info	(3S,10R,13S,17S,Z)-10-(2-methoxyvinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O3	1
1	IC50 = 303 nM
CP0222463 Compound Info	3-arylquinazolinone, 1aaj Show/Hide	C15H12N2O3	1
1	IC50 = 317 nM
CP0176182 Compound Info	(2S,3R)-3-(3-Hydroxy-phenyl)-2-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C26H27NO5S	1
1	IC50 = 318 nM
CP0046579 Compound Info	ethyl 2-acetyl-5-[(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-1,3-dihydroindene-2-carboxylate Show/Hide	C32H38O5	1
1	IC50 = 319.15 nM
CP0202445 Compound Info	(1R,2S,5S,6S,9S,10R,13S,14R,15S)-5-methylpentacyclo[12.3.3.0^{1,13}.0^{2,10}.0^{5,9}]icosane-6,15-diol Show/Hide	C21H34O2	1
1	IC50 = 322 nM
CP0186277 Compound Info	(2R,3S)-3-(4-Hydroxy-phenyl)-8-methyl-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C28H31NO4S	1
1	IC50 = 343.3 nM
CP0215949 Compound Info	(3S,10S,13S,17S,Z)-10-(but-1-enyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C22H34O2	1
1	IC50 = 361 nM
CP0034670 Compound Info	(3S,10S,13S,17S)-13-methyl-10-(prop-1-ynyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H30O2	1
1	IC50 = 381 nM
CP0144749 Compound Info	1-(4-fluorophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolin-6-ol Show/Hide	C21H18FNO	1
1	IC50 = 421 nM
CP0162129 Compound Info	3-arylquinazolinone, 1ac Show/Hide	C15H12N2O4	1
1	IC50 = 422 nM
CP0677490 Compound Info	17alpha-(1,3-Dihydro-2-tosyl-2H-indol-5-yl)-estradiol Show/Hide	C33H37NO4S	1
1	IC50 = 500.03 nM
CP0276781 Compound Info	3-arylquinazolinethione, 1bf Show/Hide	C13H9N3O3S	1
1	IC50 = 515 nM
CP0152265 Compound Info	(2R,3S)-6-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol Show/Hide	C27H28ClNO4S	1
1	IC50 = 520 nM
CP0045469 Compound Info	9a-ethyl-3,8,9,10-tetrahydroindeno[2,1-e]indazol-7-one Show/Hide	C16H16N2O	1
1	IC50 = 618 nM
CP0167082 Compound Info	3-(3-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one Show/Hide	C14H9FN2O4	1
1	IC50 = 650 nM
CP0109776 Compound Info	3-arylquinazolinethione, 1bc Show/Hide	C15H12N2O3S	1
1	IC50 = 658 nM
CP0169724 Compound Info	(8R,9S,10S,13S,14S,17S)-17-hydroxy-13-methyl-10-vinyl-1,7,8,10,11,12,13,15,16,17-decahydro-2H-cyclopenta[a]phenanthren-3(6H,9H,14H)-one Show/Hide	C20H28O2	2
1	IC50 = 780 nM
2	IC50 = 782 nM
CP0324045 Compound Info	(10S,13S,17S)-17-hydroxy-13-methyl-10-vinyl-1,7,8,10,11,12,13,15,16,17-decahydro-2H-cyclopenta[a]phenanthren-3(6H,9H,14H)-one Show/Hide	C20H28O2	1
1	IC50 = 782 nM
CP0163998 Compound Info	3-(4-Methoxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-6-ol Show/Hide	C28H31NO4S	1
1	IC50 = 792 nM
CP0336943 Compound Info	(1R,2S,5S,6S,9S,10R,14R,15R)-5-methylpentacyclo[12.3.2.0^{1,13}.0^{2,10}.0^{5,9}]nonadec-12-ene-6,15-diol Show/Hide	C20H30O2	1
1	IC50 = 854 nM
CP0062173 Compound Info	17alpha-[2,2-Bis(ethoxycarbonyl)-1,3-dihydro-2H-inden-5-yl]-estradiol Show/Hide	C33H40O6	1
1	IC50 = 1083.93 nM
CP0205163 Compound Info	3-arylquinazolinone, 1ao Show/Hide	C15H12N2O4	1
1	IC50 = 1275 nM
CP0034673 Compound Info	(3S,10R,13S,17S,E)-10-(2-methoxyvinyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O3	1
1	IC50 = 1299 nM
CP0053327 Compound Info	5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromene-4-thione Show/Hide	C15H10O4S	1
1	IC50 = 1340 nM
CP0333951 Compound Info	(1R,2S,5S,6S,9S,10R,14R)-6-hydroxy-5-methylpentacyclo[12.3.2.0^{1,13}.0^{2,10}.0^{5,9}]nonadec-12-en-15-one Show/Hide	C20H28O2	1
1	IC50 = 1460 nM
CP0170614 Compound Info	2-((3S,10S,13S,17S)-3,17-dihydroxy-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-10-yl)acetaldehyde Show/Hide	C20H30O3	1
1	IC50 = 1619 nM
CP0173009 Compound Info	(3S,10S,13S,17S)-10-(hydroxymethyl)-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C19H30O3	1
1	IC50 = 1754 nM
CP0160807 Compound Info	(8R,9S,10S,13S,14S,17S)-13-methyl-3-phenyl-10-vinyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol Show/Hide	C26H32O	1
1	IC50 = 1760 nM
CP0071097 Compound Info	2-[3-(4-hydroxyphenyl)propyl]-5-methoxyphenol Show/Hide	C16H18O3	1
1	IC50 = 1800 nM
CP0167085 Compound Info	3-arylquinazolinone, 1aas Show/Hide	C17H14N2O3	1
1	IC50 = 2302 nM
CP0160809 Compound Info	(3R,8R,9S,10S,13S,14S,17S)-3,13-dimethyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H32O2	1
1	IC50 = 2490 nM
CP0169900 Compound Info	(3S,4R,8R,9S,10S,13S,14S,17S)-4-allyl-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C23H34O2	1
1	IC50 = 3020 nM
CP0343559 Compound Info	9a-ethyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one Show/Hide	C15H15N3O	1
1	IC50 = 3041 nM
CP0205232 Compound Info	3-arylquinazolinone, 1ak Show/Hide	C13H9N3O4	1
1	IC50 = 3531 nM
CP0222461 Compound Info	3-arylquinazolinone, 1at Show/Hide	C14H10N2O4	1
1	IC50 = 3842 nM
CP0320563 Compound Info	3-arylquinazolinone, 1ap Show/Hide	C14H9IN2O4	1
1	IC50 = 3970 nM
CP0146459 Compound Info	3-arylquinazolinone, 1am Show/Hide	C14H9IN2O4	1
1	IC50 = 4081 nM
CP0374890 Compound Info	(R)-9a-ethyl-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one Show/Hide	C17H18N2O	1
1	IC50 = 4460 nM
CP0167098 Compound Info	2-ethyl-5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one Show/Hide	C16H14N2O4	1
1	IC50 = 5752 nM
CP0179273 Compound Info	3-arylquinazolinone, 1aac Show/Hide	C14H10N2O4S	1
1	IC50 = 6994 nM
CP0045464 Compound Info	3-(3-chloro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one Show/Hide	C14H9ClN2O4	1
1	IC50 = 7211 nM
CP0316541 Compound Info	3-arylquinazolinone, 1ai Show/Hide	C15H12N2O4	1
1	IC50 = 7487 nM
CP0179292 Compound Info	3-arylquinazolinone, 1aai Show/Hide	C14H11N3O3	1
1	IC50 = 8242 nM
CP0141380 Compound Info	3-arylquinazolinone, 1as Show/Hide	C14H10N2O3	1
1	IC50 = 8609 nM
CP0141377 Compound Info	2,5,7-trihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one Show/Hide	C14H10N2O5	1
1	IC50 = 9379 nM
CP0161944 Compound Info	3-arylquinazolinone, 1ab Show/Hide	C15H12N2O4	1
1	IC50 = 9525 nM
CP0276123 Compound Info	3-arylquinazolinone, 1aap Show/Hide	C16H12N2O5	1
1	IC50 = 9536 nM
CP0288405 Compound Info	3-arylquinazolinone, 1av Show/Hide	C15H12N2O4	1
1	IC50 = 11371 nM
CP0274862 Compound Info	3-arylquinazolinone, 1aam Show/Hide	C15H9F3N2O6S	1
1	IC50 = 11979 nM
CP0109772 Compound Info	3-arylquinazolinone, 1an Show/Hide	C14H8I2N2O4	1
1	IC50 = 12298 nM
CP0044826 Compound Info	2-chloro-5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one Show/Hide	C14H9ClN2O4	1
1	IC50 = 13426 nM
CP0283226 Compound Info	3-arylquinazolinone, 1aao Show/Hide	C16H12N2O3	1
1	IC50 = 17004 nM
CP0283224 Compound Info	3-arylquinazolinone, 1au Show/Hide	C14H10N2O3	1
1	IC50 = 18472 nM
CP0211271 Compound Info	3-arylquinazolinone, 1aaq Show/Hide	C20H14N2O3	1
1	IC50 = 30661 nM
CP0045448 Compound Info	3-arylquinazolinone, 1al Show/Hide	C13H9N3O4	1
1	IC50 = 51696 nM
CP0140876 Compound Info	3-arylquinazolinone, 1aab Show/Hide	C15H12N2O4S	1
1	IC50 = 72848 nM
CP0236221 Compound Info	3-arylquinazolinone, 1aal Show/Hide	C15H9N3O3	1
1	IC50 = 73677 nM
CP0192123 Compound Info	(1S,2S,5S,6S,9S,10R,15S)-5-methyl-16-oxapentacyclo[13.3.2.0^{1,13}.0^{2,10}.0^{5,9}]icos-12-en-6-ol Show/Hide	C20H30O2	1
1	IC50 > 10000 nM
CP0216452 Compound Info	(1S,2S,5S,6S,9S,10R,14S,19R)-6,19-dihydroxy-5-methylpentacyclo[12.3.2.0^{1,13}.0^{2,10}.0^{5,9}]nonadec-12-en-15-one Show/Hide	C20H28O3	1
1	IC50 > 10000 nM
CP0254042 Compound Info	(1S,2S,5S,6S,9S,10R,15S)-6-hydroxy-5-methyl-16-oxapentacyclo[13.3.2.0^{1,13}.0^{2,10}.0^{5,9}]icos-12-en-17-one Show/Hide	C20H28O3	1
1	IC50 > 10000 nM
CP0254043 Compound Info	(1S,2S,5S,6S,9S,10R,19R)-6,19-dihydroxy-5-methylpentacyclo[10.5.2.0^{1,13}.0^{2,10}.0^{5,9}]nonadec-13-en-15-one Show/Hide	C20H28O3	1
1	IC50 > 10000 nM
CP0264225 Compound Info	(1S,2S,5S,6S,9S,10R,14S,19S)-6,19-dihydroxy-5-methylpentacyclo[12.3.2.0^{1,13}.0^{2,10}.0^{5,9}]nonadec-12-en-15-one Show/Hide	C20H28O3	1
1	IC50 > 10000 nM
CP0047174 Compound Info	(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one Show/Hide	C21H28O5	1
1	IC50 > 10000 nM
CP0212963 Compound Info	(2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0.0^{2,6}]trideca-1(13),9,11-trien-12-ol Show/Hide	C18H18O3	2
1	Ki = 0.17 nM
2	Ki = 0.19 nM
CP0696841 Compound Info	(E)-2-chloro-4,4'-dihydroxybiphenyl-3-carbaldehyde oxime Show/Hide	C13H10ClNO3	1
1	Ki = 0.38 nM
CP0218083 Compound Info	(2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0.0^{2,6}]trideca-1(13),9,11-trien-12-ol Show/Hide	C18H18O3	2
1	Ki = 0.47 nM
2	Ki = 1.54 nM
CP0696842 Compound Info	(E)-2-chloro-3'-fluoro-4,4'-dihydroxybiphenyl-3-carbaldehyde oxime Show/Hide	C13H9ClFNO3	1
1	Ki = 0.57 nM
CP0755214 Compound Info	FERB-033 Show/Hide	C13H9ClFNO3	1
1	Ki = 7.1 nM
CP0708706 Compound Info	3-chloro-4-(4-hydroxyphenyl)salicylaldoxime Show/Hide	C13H10ClNO3	1
1	Ki = 12 nM
CP0086411 Compound Info	[3-(trifluoromethyl)phenyl] 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H25F3O7S	1
1	Ki = 12.8 nM
CP0217788 Compound Info	4-(2-{4-[3-(4-Chloro-phenyl)-propylsulfanyl]-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino}-ethyl)-phenol Show/Hide	C24H29ClN6OS	1
1	Ki = 15 nM
CP0220522 Compound Info	4-[2-(4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol Show/Hide	C25H32ClN7O	1
1	Ki = 15 nM
CP0237075 Compound Info	4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-[1,3,5]triazin-2-ylamino}-ethyl)-phenol Show/Hide	C27H36ClN7O2	1
1	Ki = 15 nM
CP0292305 Compound Info	4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol Show/Hide	C25H32FN7O	1
1	Ki = 15 nM
CP0232128 Compound Info	(3-chlorophenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H25ClO7S	1
1	Ki = 23.94 nM
CP0113654 Compound Info	4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[4-(2-methyl-thiazol-4-ylmethyl)-piperazin-1-yl]-[1,3,5]triazin-2-ylamino}-ethyl)-phenol Show/Hide	C30H37ClN8OS	1
1	Ki = 25 nM
CP0350140 Compound Info	8-[4-[6-(4-hydroxyphenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C32H33NO9S	1
1	Ki = 39.04 nM
CP0087464 Compound Info	4-[2-[[4-[methyl-[[(1R,2S)-2-phenylcyclopropyl]methyl]amino]-6-piperazin-1-yl-1,3,5-triazin-2-yl]amino]ethyl]phenol Show/Hide	C26H33N7O	1
1	Ki = 40 nM
CP0115793 Compound Info	(2-ethylphenyl) 6-[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C36H34O7S	1
1	Ki = 40.12 nM
CP0110120 Compound Info	4-[2-(4-hydroxyphenyl)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol Show/Hide	C20H11F6N3O2	1
1	Ki = 48 nM
CP0659163 Compound Info	(exo)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonic acid phenyl ester Show/Hide	C24H20O6S	1
1	Ki = 49.06 nM
CP0304520 Compound Info	8-[4-[6-(4-fluorophenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C32H32FNO8S	1
1	Ki = 49.78 nM
CP0114952 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-naphthalen-2-yloxysulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C36H35NO8S	1
1	Ki = 55.65 nM
CP0563035 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[methyl(phenyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H36N2O7S	1
1	Ki = 56.67 nM
CP0061392 Compound Info	naphthalen-1-yl 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C36H28O7S	1
1	Ki = 59.71 nM
CP0093215 Compound Info	8-[4-[6-(4-bromophenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C32H32BrNO8S	1
1	Ki = 60.5 nM
CP0035126 Compound Info	4-(3-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl)phenol Show/Hide	C27H24F6N4O2	1
1	Ki = 71 nM
CP0121037 Compound Info	[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl] 5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C34H30O8S	1
1	Ki = 73.44 nM
CP0058811 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-(3-methoxyphenoxy)sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H35NO9S	1
1	Ki = 81.53 nM
CP0659161 Compound Info	(exo-rac)-8-(4-(3-(4-Hydroxyphenyl)-6-(p-tolyloxysulfonyl)-7-oxabicyclo-[2.2.1]hept-2-en-2-yl)phenylamino)-8-oxooctanoic Acid Show/Hide	C33H35NO8S	1
1	Ki = 87.32 nM
CP0071880 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-(2-methylphenoxy)sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H35NO8S	1
1	Ki = 91.89 nM
CP0193114 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-(2-methoxyphenoxy)sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H35NO9S	1
1	Ki = 95.24 nM
CP0089162 Compound Info	8-[4-[6-(3-hydroxyphenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C32H33NO9S	1
1	Ki = 101.49 nM
CP0093222 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-naphthalen-1-yloxysulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C36H35NO8S	2
1	Ki = 101.49 nM
2	Ki = 108.58 nM
CP0563076 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(4-hydroxyphenyl)-methylsulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H36N2O8S	1
1	Ki = 101.79 nM
CP0185108 Compound Info	naphthalen-2-yl 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C36H36N2O8S	1
1	Ki = 102.41 nM
CP0061390 Compound Info	(3-methylphenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H28O7S	1
1	Ki = 115.08 nM
CP0077201 Compound Info	phenyl (1R,2S,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C24H20O6S	1
1	Ki = 121.53 nM
CP0046306 Compound Info	[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl] 5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H34N2O9S	1
1	Ki = 126.87 nM
CP0198856 Compound Info	(3-methoxyphenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H28O8S	1
1	Ki = 137.79 nM
CP0115795 Compound Info	[3-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl] 5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C34H30O8S	1
1	Ki = 140.14 nM
CP0118837 Compound Info	phenyl 5-(4-hydroxyphenyl)-6-[4-[(E)-2-phenylethenyl]phenyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H26O5S	1
1	Ki = 167.48 nM
CP0275052 Compound Info	4-(3-{4-[2-(dimethylamino)ethoxy]phenyl}-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl)phenol Show/Hide	C24H20F6N4O2	1
1	Ki = 178 nM
CP0262746 Compound Info	(4-chlorophenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H25ClO7S	1
1	Ki = 179.91 nM
CP0228150 Compound Info	(4-hydroxyphenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H26O8S	1
1	Ki = 180.7 nM
CP0045922 Compound Info	8-[4-[6-(4-chlorophenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C32H32ClNO8S	1
1	Ki = 200.01 nM
CP0098165 Compound Info	phenyl 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H26O7S	1
1	Ki = 226.37 nM
CP0121039 Compound Info	(2-chlorophenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H25ClO7S	1
1	Ki = 262.42 nM
CP0118835 Compound Info	(4-methylphenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H28O7S	1
1	Ki = 284.14 nM
CP0118731 Compound Info	(4-phenylphenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C38H30O7S	1
1	Ki = 302.94 nM
CP0117744 Compound Info	[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl] 5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H26O8S	1
1	Ki = 314.5 nM
CP0301323 Compound Info	8-[4-[6-[ethyl(phenyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H38N2O7S	1
1	Ki = 346.94 nM
CP0228025 Compound Info	(2-methylphenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H28O7S	1
1	Ki = 374.55 nM
CP0301321 Compound Info	5,6-bis(4-hydroxyphenyl)-N-phenyl-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide Show/Hide	C26H22F3NO5S	1
1	Ki = 453.33 nM
CP0229838 Compound Info	(4-fluorophenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H25FO7S	1
1	Ki = 473.56 nM
CP0329630 Compound Info	(4-bromophenyl) 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H25BrO7S	1
1	Ki = 528.21 nM
CP0056229 Compound Info	8-[3-[[5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-en-2-yl]sulfonyloxy]anilino]-8-oxooctanoic acid Show/Hide	C32H33NO9S	1
1	Ki = 629.63 nM
CP0689907 Compound Info	(exo-rac)-8-(4-(3-(4-Hydroxyphenyl)-6-(phenoxysulfonyl)-7-oxabicyclo-[2.2.1]hept-2-en-2-yl)phenylamino)-8-oxooctanoic Acid Show/Hide	C32H33NO8S	1
1	Ki = 653.85 nM
CP0061433 Compound Info	[4-[(E)-2-phenylethenyl]phenyl] 5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H26O6S	1
1	Ki = 675.41 nM
CP0118730 Compound Info	[2-(trifluoromethyl)phenyl] 6-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H25F3O7S	1
1	Ki = 722.81 nM
CP0708265 Compound Info	Methyl 8-(4-(5,6-Bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-en-2-yl-sulfonyloxy)phenylamino)-8-oxooctanoate Show/Hide	C33H35NO9S	1
1	Ki = 755.56 nM
CP0674602 Compound Info	8-(4-(5,6-Bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-en-2-ylsulfonyloxy)phenylamino)-8-oxooctanoic Acid Show/Hide	C32H33NO9S	1
1	Ki = 772.73 nM
CP0262742 Compound Info	(3-methoxyphenyl) 6-[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C35H32O8S	1
1	Ki = 1248.48 nM
CP0485104 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(4-methylphenyl)-(2,2,2-trifluoroethyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H37F3N2O7S	1
1	Ki = 1307.69 nM
CP0572522 Compound Info	8-[4-[6-[benzyl(2,2,2-trifluoroethyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H37F3N2O7S	1
1	Ki = 1545.45 nM
CP0219036 Compound Info	8-[4-[6-[(4-chlorophenyl)-ethylsulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H37ClN2O7S	1
1	Ki = 1789.47 nM
CP0301322 Compound Info	8-[4-[6-[ethyl-(3-methylphenyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H40N2O7S	1
1	Ki = 2000 nM
CP0058817 Compound Info	(2-methylphenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H36N2O8S	1
1	Ki = 2125 nM
CP0244862 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(3-methoxyphenyl)-(2,2,2-trifluoroethyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H37F3N2O8S	1
1	Ki = 2125 nM
CP0046304 Compound Info	(4-bromophenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H33BrN2O8S	1
1	Ki = 2428.57 nM
CP0561692 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(3-methylphenyl)-(2,2,2-trifluoroethyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H37F3N2O7S	1
1	Ki = 2428.57 nM
CP0219033 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[methyl-(3-methylphenyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H38N2O7S	1
1	Ki = 2615.38 nM
CP0151573 Compound Info	2,4-diisobutylamino-6-isopentylpyrimidine Show/Hide	C17H32N4	1
1	Ki = 2800 nM
CP0089161 Compound Info	(2-methoxyphenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H36N2O9S	1
1	Ki = 2833.33 nM
CP0244865 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(3-methoxyphenyl)-methylsulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H38N2O8S	1
1	Ki = 2833.33 nM
CP0507394 Compound Info	8-[4-[6-[ethyl-(3-methoxyphenyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H40N2O8S	1
1	Ki = 2833.33 nM
CP0507395 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[methyl-(4-methylphenyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H38N2O7S	1
1	Ki = 2833.33 nM
CP0507397 Compound Info	8-[4-[6-[(2-chlorophenyl)-ethylsulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H37ClN2O7S	1
1	Ki = 2833.33 nM
CP0035186 Compound Info	(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one Show/Hide	C29H35NO2	2
1	Ki = 2876 nM
2	Ki > 750 nM
CP0253982 Compound Info	8-[4-[6-[(2-bromophenyl)-ethylsulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H37BrN2O7S	1
1	Ki = 3090.3 nM
CP0199030 Compound Info	phenyl 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H34N2O8S	1
1	Ki = 3090.9 nM
CP0507393 Compound Info	8-[4-[6-[ethyl-(4-methoxyphenyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H40N2O8S	1
1	Ki = 3090.91 nM
CP0046302 Compound Info	(4-fluorophenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H33FN2O8S	1
1	Ki = 3400 nM
CP0219034 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[methyl(naphthalen-1-yl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C37H38N2O7S	1
1	Ki = 3400 nM
CP0253984 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[phenyl(2,2,2-trifluoroethyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H35F3N2O7S	1
1	Ki = 3400 nM
CP0237702 Compound Info	[3-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl] 5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C32H26O8S	1
1	Ki = 4577.8 nM
CP0549046 Compound Info	8-[4-[6-[ethyl-(4-methylphenyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H40N2O7S	1
1	Ki = 4857.14 nM
CP0056227 Compound Info	(3-methylphenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H36N2O8S	1
1	Ki > 5000 nM
CP0109146 Compound Info	(4-methylphenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C33H36N2O8S	1
1	Ki > 5000 nM
CP0244861 Compound Info	8-[4-[6-[(2-chlorophenyl)-methylsulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H35ClN2O7S	1
1	Ki > 5000 nM
CP0253985 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(4-methoxyphenyl)-(2,2,2-trifluoroethyl)sulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C35H37F3N2O8S	1
1	Ki > 5000 nM
CP0301311 Compound Info	8-[4-[6-[(4-chlorophenyl)-methylsulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C33H35ClN2O7S	1
1	Ki > 5000 nM
CP0485103 Compound Info	8-[4-[6-[ethyl-(4-hydroxyphenyl)sulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H38N2O8S	1
1	Ki > 5000 nM
CP0507396 Compound Info	8-[4-[3-(4-hydroxyphenyl)-6-[(4-methoxyphenyl)-methylsulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid Show/Hide	C34H38N2O8S	1
1	Ki > 5000 nM
CP0090808 Compound Info	3-(3-fluorophenyl)-1-(4-methylphenyl)-3-(4-nitroanilino)propan-1-one Show/Hide	C22H19FN2O3	1
1	Ki > 10000 nM
CP0077197 Compound Info	phenyl 6-[4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate Show/Hide	C34H30O7S	1
1	Ki > 10000 nM

Clinical Information about the Protein

Target 1 ( Estrogen receptor beta (ESR2) )

Target Type	Successful Target
Disease	11 Target-related Diseases				11
1	Breast cancer [ICD-11: 2C60-2C65]
2	Cushing disease [ICD-11: 5A70]
3	Hot flushes [ICD-11: GA30]
4	Inflammatory bowel disease [ICD-11: DD72]
5	Prostate hyperplasia [ICD-11: GA90]
6	Menopause symptom [ICD-11: GA30.0]
7	Trematode infection [ICD-11: 1F8Y]
8	Irregularities [ICD-11: N.A.]
9	Estrogen deficiency [ICD-11: FB83.0Y]
10	Thrombocytopenia [ICD-11: 3B64]
11	Carcinoma [ICD-11: 2A00-2F9Z]
Approved Drug(s)	2 Approved Drugs				2
1	ARZOXIFENE	Drug Info	Approved	Breast cancer
2	Trilostane	Drug Info	Approved	Cushing disease
Clinical Trial Drug(s)	4 Clinical Trial Drugs				4
1	AUS-131	Drug Info	Phase 2	Hot flushes
2	ERB-041	Drug Info	Phase 2	Inflammatory bowel disease
3	Erteberel	Drug Info	Phase 2	Prostate hyperplasia
4	Genistein	Drug Info	Phase 2/3	Menopause symptom
Discontinued Drug(s)	8 Discontinued Drugs				8
1	BITHIONOL	Drug Info	Withdrawn from market	Trematode infection
2	HEXESTROL	Drug Info	Withdrawn from market	Irregularities
3	EM-800	Drug Info	Discontinued in Phase 3	Estrogen deficiency
4	ERA-923	Drug Info	Discontinued in Phase 2	Breast cancer
5	ERB-196	Drug Info	Discontinued in Phase 1	Inflammatory bowel disease
6	HE2100	Drug Info	Discontinued in Phase 1	Thrombocytopenia
7	ICI-164384	Drug Info	Terminated	Breast cancer
8	ZK-119010	Drug Info	Terminated	Carcinoma

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han