General Information of the Compound
| Compound ID |
CP0003923
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| Compound Name |
(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine
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| Synonyms |
Citofen
(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)
(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
1-p-beta-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
10540-29-1
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
CCRIS 3275
CHEMBL83
Citofen
Crisafeno
Diemon
EINECS 234-118-0
Gen-Tamoxifen
HSDB 6782
ICI 47699
ICI-46474
Istubal (TN)
Istubol
Nolvadex (TN)
Nolvadex-D
Nourytam
Novaldex
Novo-Tamoxifen
Oncomox
Pms-Tamoxifen
Retaxim
Soltamox
TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))
TRANS FORM OF TAMOXIFEN
Tamizam
Tamone
Tamoplex (TN)
Tamoxen
Tamoxifen
Tamoxifen (Hormonal therapy)
Tamoxifen (INN)
Tamoxifen (TN)
Tamoxifen (Z)
Tamoxifen [INN:BAN]
Tamoxifen and its salts
Tamoxifene
Tamoxifene [INN-French]
Tamoxifeno
Tamoxifeno [INN-Spanish]
Tamoxifeno;Tamoxifenum
Tamoxifenum
Tamoxifenum [INN-Latin]
Tomaxithen
Trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
Trans-Tamoxifen
UNII-094ZI81Y45
Valodex
Valodex (TN)
[3H]tamoxifen
tamoxifen
trans-Tamoxifen
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| Structure |
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| Formula |
C26H29NO
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| Molecular Weight |
371.524
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| Canonical SMILES |
CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
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| InChI |
InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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| InChIKey |
NKANXQFJJICGDU-QPLCGJKRSA-N
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| CAS |
10540-29-1
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Protein ID: PT01546, ATP-dependent translocase ABCB1
Protein ID: PT04542, Bile salt export pump
Protein ID: PT00886, Estrogen receptor
Cell-based Assay
Protein ID: PT00889, Estrogen receptor beta
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01172, Progesterone receptor
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT02513, Steroid hormone receptor ERR1
Clinical Information about the Compound