Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000078
Cell Line Name	T-47D
Synonyms	T-47-D T47-D T47D:A T47D
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0553
Tissue Information	Pleural effusion
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT01498, 17-beta-hydroxysteroid dehydrogenase type 1

Protein Info

Compound ID	Compound Name	Compound Formula
CP0396139 Compound Info	(2,6-difluoro-3-hydroxyphenyl)-[5-(4-hydroxyphenyl)thiophen-2-yl]methanone Show/Hide	C17H10F2O3S	1
1	IC50 = 7.9 nM Bioactivity Info	TI LI LO TS
CP0148493 Compound Info	(4-fluoro-3-hydroxyphenyl)-(6-hydroxy-1,3-benzothiazol-2-yl)methanone Show/Hide	C14H8FNO3S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0286146 Compound Info	[5-(3-fluoro-4-hydroxyphenyl)thiophen-2-yl]-(3-hydroxyphenyl)methanone Show/Hide	C17H11FO3S	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0389067 Compound Info	[4-[5-(2,6-difluoro-3-hydroxybenzoyl)thiophen-2-yl]-2-fluorophenyl] sulfamate Show/Hide	C17H10F3NO5S2	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0396140 Compound Info	[2-chloro-4-[5-(2,6-difluoro-3-hydroxybenzoyl)thiophen-2-yl]phenyl] sulfamate Show/Hide	C17H10ClF2NO5S2	1
1	IC50 = 22.2 nM Bioactivity Info	TI LI LO TS
CP0387571 Compound Info	2-((8R,9S,13S,14S,16R)-2-ethyl-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-yl)-N-(pyridin-3-ylmethyl)acetamide Show/Hide	C28H34N2O3	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0210432 Compound Info	[5-(4-hydroxy-3-methylphenyl)thiophen-2-yl]-(3-hydroxyphenyl)methanone Show/Hide	C18H14O3S	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0084961 Compound Info	3-[[(8R,9S,13S,14S,16R,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]methyl]benzamide Show/Hide	C26H31NO3	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0159168 Compound Info	(3-hydroxyphenyl)(5-(4-hydroxyphenyl)thiophen-2-yl)methanone Show/Hide	C17H12O3S	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0440057 Compound Info	2-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl]-N-(pyridin-3-ylmethyl)acetamide Show/Hide	C26H30N2O3	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0148492 Compound Info	2,6-difluoro-3-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide Show/Hide	C14H8F2N2O3S	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0485763 Compound Info	[4-[5-(2,6-difluoro-3-hydroxybenzoyl)thiophen-2-yl]-3-fluorophenyl] sulfamate Show/Hide	C17H10F3NO5S2	1
1	IC50 = 42.1 nM Bioactivity Info	TI LI LO TS
CP0478318 Compound Info	[3-chloro-4-[5-(2,6-difluoro-3-hydroxybenzoyl)thiophen-2-yl]phenyl] sulfamate Show/Hide	C17H10ClF2NO5S2	1
1	IC50 = 60.9 nM Bioactivity Info	TI LI LO TS
CP0134163 Compound Info	3-[[(8R,9S,13S,14S,16R,17S)-3-(2-bromoethyl)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]methyl]benzamide Show/Hide	C28H34BrNO2	2
1	IC50 = 68 nM Bioactivity Info	TI LI LO TS
2	IC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0098537 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]methanesulfonamide Show/Hide	C23H19NO4S	1
1	IC50 = 71 nM Bioactivity Info	TI LI LO TS
CP0076189 Compound Info	2-fluoro-3-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide Show/Hide	C14H9FN2O3S	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0243145 Compound Info	[2-(4-hydroxy-3-methylphenyl)-1,3-thiazol-5-yl]-(3-hydroxyphenyl)methanone Show/Hide	C17H13NO3S	1
1	IC50 = 107 nM Bioactivity Info	TI LI LO TS
CP0853836 Compound Info	(S)-3-Hydroxy-16-hydroxymethylene-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one Show/Hide	C19H22O3	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0053398 Compound Info	1,6-Bis(3-hydroxyphenyl)-2-naphthol Show/Hide	C22H16O3	1
1	IC50 = 115 nM Bioactivity Info	TI LI LO TS
CP0278450 Compound Info	[5-(3-chloro-4-hydroxyphenyl)thiophen-2-yl]-(3-hydroxyphenyl)methanone Show/Hide	C17H11ClO3S	1
1	IC50 = 126 nM Bioactivity Info	TI LI LO TS
CP0342677 Compound Info	2-fluoro-5-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide Show/Hide	C14H9FN2O3S	1
1	IC50 = 152 nM Bioactivity Info	TI LI LO TS
CP0395603 Compound Info	3-[[(8R,9S,13S,14S,16R,17S)-3-(3-bromopropyl)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]methyl]benzamide Show/Hide	C29H36BrNO2	1
1	IC50 = 153 nM Bioactivity Info	TI LI LO TS
CP0202860 Compound Info	2-cyano-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C29H20N2O4S	1
1	IC50 = 157 nM Bioactivity Info	TI LI LO TS
CP0162514 Compound Info	6-(3-Hydroxyphenyl)-1-(pyridin-3-yl)-2-naphthol Show/Hide	C21H15NO2	1
1	IC50 = 165 nM Bioactivity Info	TI LI LO TS
CP0387939 Compound Info	3-[[(8R,9S,13S,14S,16R,17S)-3-(2-bromoethoxy)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]methyl]benzamide Show/Hide	C28H34BrNO3	1
1	IC50 = 172 nM Bioactivity Info	TI LI LO TS
CP0371772 Compound Info	(S)-6a-Methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthren-2-ol Show/Hide	C19H22N2O	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0140150 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H21NO4S	1
1	IC50 = 196 nM Bioactivity Info	TI LI LO TS
CP0054358 Compound Info	6-(3-Hydroxy-phenyl)-naphthalen-2-ol Show/Hide	C16H12O2	1
1	IC50 = 229 nM Bioactivity Info	TI LI LO TS
CP0154262 Compound Info	N-[4-[[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]sulfamoyl]phenyl]acetamide Show/Hide	C30H24N2O5S	1
1	IC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0309109 Compound Info	3-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide Show/Hide	C14H10N2O3S	1
1	IC50 = 245 nM Bioactivity Info	TI LI LO TS
CP0154263 Compound Info	2,2,2-trifluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]ethanesulfonamide Show/Hide	C24H18F3NO4S	1
1	IC50 = 246 nM Bioactivity Info	TI LI LO TS
CP0086194 Compound Info	(6-hydroxy-1,3-benzothiazol-2-yl)-(3-hydroxy-4-methylphenyl)methanone Show/Hide	C15H11NO3S	1
1	IC50 = 258 nM Bioactivity Info	TI LI LO TS
CP0056064 Compound Info	6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol Show/Hide	C22H16O2	1
1	IC50 = 281 nM Bioactivity Info	TI LI LO TS
CP0431511 Compound Info	(S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthrene-9-carboxylic acid (2-pyridin-3-yl-ethyl)-amide Show/Hide	C27H30N4O2	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0485949 Compound Info	ethyl 2-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl]acetate Show/Hide	C22H28O4	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0140149 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]thiophene-2-sulfonamide Show/Hide	C26H19NO4S2	1
1	IC50 = 316 nM Bioactivity Info	TI LI LO TS
CP0485951 Compound Info	(8R,9S,13S,14S,16R)-16-(ethoxymethyl)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one Show/Hide	C21H28O3	1
1	IC50 = 320 nM Bioactivity Info	TI LI LO TS
CP0044042 Compound Info	(1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one Show/Hide	C18H22O2	1
1	IC50 = 330 nM Bioactivity Info	TI LI LO TS
CP0508224 Compound Info	(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-6,17-dione Show/Hide	C18H20O3	1
1	IC50 = 340 nM Bioactivity Info	TI LI LO TS
CP0309110 Compound Info	(2,5-dihydroxyphenyl)-(6-hydroxy-1,3-benzothiazol-2-yl)methanone Show/Hide	C14H9NO4S	1
1	IC50 = 365 nM Bioactivity Info	TI LI LO TS
CP0288171 Compound Info	[5-(3-ethyl-4-hydroxyphenyl)thiophen-2-yl]-(3-hydroxyphenyl)methanone Show/Hide	C19H16O3S	1
1	IC50 = 367 nM Bioactivity Info	TI LI LO TS
CP0371776 Compound Info	2-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl]-N-(oxolan-2-ylmethyl)acetamide Show/Hide	C25H33NO4	1
1	IC50 = 380 nM Bioactivity Info	TI LI LO TS
CP0154261 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-3-nitrobenzenesulfonamide Show/Hide	C28H20N2O6S	1
1	IC50 = 396 nM Bioactivity Info	TI LI LO TS
CP0142664 Compound Info	3-cyano-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C29H20N2O4S	1
1	IC50 = 402 nM Bioactivity Info	TI LI LO TS
CP0163984 Compound Info	2-fluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H20FNO4S	1
1	IC50 = 429 nM Bioactivity Info	TI LI LO TS
CP0465441 Compound Info	3-[[(8R,9S,13S,14S,16R,17S)-3-(bromomethyl)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]methyl]benzamide Show/Hide	C27H32BrNO2	1
1	IC50 = 430 nM Bioactivity Info	TI LI LO TS
CP0306868 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-3-methylbenzenesulfonamide Show/Hide	C29H23NO4S	1
1	IC50 = 440 nM Bioactivity Info	TI LI LO TS
CP0259627 Compound Info	(8R,9S,13S,14S,16R,17S)-16-(3-bromopropyl)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol Show/Hide	C21H29BrO2	1
1	IC50 = 460 nM Bioactivity Info	TI LI LO TS
CP0515928 Compound Info	2-hydroxy-6a-methyl-5,6,6a,8,10,10a,10b,11-octahydro-4bH-7,8-diaza-pentaleno[2,1-a]phenanthren-12-one Show/Hide	C19H20N2O2	1
1	IC50 = 460 nM Bioactivity Info	TI LI LO TS
CP0146863 Compound Info	3-fluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H20FNO4S	1
1	IC50 = 462 nM Bioactivity Info	TI LI LO TS
CP0161103 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-2-nitrobenzenesulfonamide Show/Hide	C28H20N2O6S	1
1	IC50 = 462 nM Bioactivity Info	TI LI LO TS
CP0156088 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]quinoline-6-sulfonamide Show/Hide	C31H22N2O4S	1
1	IC50 = 498 nM Bioactivity Info	TI LI LO TS
CP0508205 Compound Info	(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-N-(pyridin-3-ylmethyl)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16-carboxamide Show/Hide	C25H30N2O3	1
1	IC50 = 510 nM Bioactivity Info	TI LI LO TS
CP0140151 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-2-methylbenzenesulfonamide Show/Hide	C29H23NO4S	1
1	IC50 = 525 nM Bioactivity Info	TI LI LO TS
CP0428063 Compound Info	(S)-8-(2-Methoxy-ethyl)-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthren-2-ol Show/Hide	C22H28N2O2	1
1	IC50 = 530 nM Bioactivity Info	TI LI LO TS
CP0202858 Compound Info	4-cyano-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C29H20N2O4S	1
1	IC50 = 555 nM Bioactivity Info	TI LI LO TS
CP0261616 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-4-methylbenzenesulfonamide Show/Hide	C29H23NO4S	1
1	IC50 = 633 nM Bioactivity Info	TI LI LO TS
CP0092222 Compound Info	4-fluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H20FNO4S	1
1	IC50 = 637 nM Bioactivity Info	TI LI LO TS
CP0163924 Compound Info	4-bromo-2,5-difluoro-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H18BrF2NO4S	1
1	IC50 = 646 nM Bioactivity Info	TI LI LO TS
CP0120458 Compound Info	6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)naphthalen-2-ol Show/Hide	C22H17NO3	1
1	IC50 = 670 nM Bioactivity Info	TI LI LO TS
CP0244800 Compound Info	3-hydroxy-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H21NO5S	1
1	IC50 = 701 nM Bioactivity Info	TI LI LO TS
CP0448596 Compound Info	3-((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,12-octahydro-5H-7,8-diaza-pentaleno[2,1-a]phenanthren-8-yl)-propionitrile Show/Hide	C22H25N3O	1
1	IC50 = 730 nM Bioactivity Info	TI LI LO TS
CP0161105 Compound Info	N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]-4-nitrobenzenesulfonamide Show/Hide	C28H20N2O6S	1
1	IC50 = 753 nM Bioactivity Info	TI LI LO TS
CP0442107 Compound Info	(S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthrene-9-carboxylic acid (pyridin-3-ylmethyl)-amide Show/Hide	C26H28N4O2	1
1	IC50 = 780 nM Bioactivity Info	TI LI LO TS
CP0460175 Compound Info	(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-N-(1-phenylethyl)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16-carboxamide Show/Hide	C27H33NO3	1
1	IC50 = 810 nM Bioactivity Info	TI LI LO TS
CP0436226 Compound Info	(S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthrene-9-carboxylic acid (pyridin-2-ylmethyl)-amide Show/Hide	C26H28N4O2	1
1	IC50 = 880 nM Bioactivity Info	TI LI LO TS
CP0448595 Compound Info	((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,12-octahydro-5H-7,8-diaza-pentaleno[2,1-a]phenanthren-8-yl)-acetic acid methyl ester Show/Hide	C22H26N2O3	1
1	IC50 = 920 nM Bioactivity Info	TI LI LO TS
CP0428019 Compound Info	(S)-9-Hydroxymethyl-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthren-2-ol Show/Hide	C20H24N2O2	1
1	IC50 = 950 nM Bioactivity Info	TI LI LO TS
CP0161106 Compound Info	4-hydroxy-N-[3-[2-hydroxy-6-(3-hydroxyphenyl)naphthalen-1-yl]phenyl]benzenesulfonamide Show/Hide	C28H21NO5S	1
1	IC50 = 1009 nM Bioactivity Info	TI LI LO TS
CP0877810 Compound Info	(S)-3-Hydroxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthrene-16,17-dione 16-oxime Show/Hide	C18H21NO3	1
1	IC50 = 1100 nM Bioactivity Info	TI LI LO TS
CP0113994 Compound Info	1-[1-(benzenesulfonyl)indol-4-yl]-6-(3-hydroxyphenyl)naphthalen-2-ol Show/Hide	C30H21NO4S	1
1	IC50 = 1100 nM Bioactivity Info	TI LI LO TS
CP0371775 Compound Info	2-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl]-N-methylacetamide Show/Hide	C21H27NO3	1
1	IC50 = 1500 nM Bioactivity Info	TI LI LO TS
CP0478012 Compound Info	5-(4-hydroxyphenyl)-2,3-dihydroinden-1-one Show/Hide	C15H12O2	1
1	IC50 = 1700 nM Bioactivity Info	TI LI LO TS
CP0515068 Compound Info	4-[4-(3-ethyl-4-hydroxyphenyl)phenyl]-2,2-dimethyl-4-oxo-N-(pyridin-3-ylmethyl)butanamide Show/Hide	C26H28N2O3	1
1	IC50 = 1800 nM Bioactivity Info	TI LI LO TS
CP0445646 Compound Info	(S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthrene-9-carboxylic acid ethyl ester Show/Hide	C22H26N2O3	1
1	IC50 = 1850 nM Bioactivity Info	TI LI LO TS
CP0926856 Compound Info	3-hydroxy-13-methyl-8,9,11,12,13,14,15,16-octahydro-7H-cyclopenta[a]phenanthrene-6,17-dione dioxime Show/Hide	C18H22N2O3	1
1	IC50 = 1900 nM Bioactivity Info	TI LI LO TS
CP0523779 Compound Info	5-(3-ethyl-4-hydroxyphenyl)-2,3-dihydroinden-1-one Show/Hide	C17H16O2	1
1	IC50 = 2000 nM Bioactivity Info	TI LI LO TS
CP0404830 Compound Info	(S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthrene-9-carboxylic acid (1-methyl-1H-pyrrol-2-ylmethyl)-amide Show/Hide	C26H30N4O2	1
1	IC50 = 2300 nM Bioactivity Info	TI LI LO TS
CP0442104 Compound Info	(S)-6a,8-Dimethyl-4b,5,6,6a,8,10,10a,10b,11,12-decahydro-7,8-diaza-pentaleno[2,1-a]phenanthren-2-ol Show/Hide	C20H24N2O	1
1	IC50 = 2750 nM Bioactivity Info	TI LI LO TS
CP0427977 Compound Info	5-(3-fluoro-4-hydroxyphenyl)-2,3-dihydroinden-1-one Show/Hide	C15H11FO2	1
1	IC50 = 2900 nM Bioactivity Info	TI LI LO TS
CP0433382 Compound Info	4-[4-(3-ethyl-4-hydroxyphenyl)phenyl]-4-oxo-N-(pyridin-3-ylmethyl)butanamide Show/Hide	C24H24N2O3	1
1	IC50 = 3700 nM Bioactivity Info	TI LI LO TS
CP0516372 Compound Info	1-[4-(4-hydroxy-2-methylphenyl)phenyl]ethanone Show/Hide	C15H14O2	1
1	IC50 = 3700 nM Bioactivity Info	TI LI LO TS
CP0525327 Compound Info	1-[4-(4-hydroxyphenyl)phenyl]ethanone Show/Hide	C14H12O2	1
1	IC50 = 3700 nM Bioactivity Info	TI LI LO TS
CP0371771 Compound Info	(8R,9S,13S,14S,16E,17S)-13-methyl-16-(pyridin-4-ylmethylidene)-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C24H27NO2	1
1	IC50 = 4100 nM Bioactivity Info	TI LI LO TS
CP0427975 Compound Info	2-[6-(3-ethyl-4-hydroxyphenyl)-3-oxo-1,2-dihydroinden-2-yl]-N-(pyridin-3-ylmethyl)acetamide Show/Hide	C25H24N2O3	1
1	IC50 = 4700 nM Bioactivity Info	TI LI LO TS
CP0478114 Compound Info	1-(7-hydroxy-9H-fluoren-2-yl)ethanone Show/Hide	C15H12O2	1
1	IC50 = 4800 nM Bioactivity Info	TI LI LO TS
CP0427974 Compound Info	1-[4-(3-ethyl-4-hydroxyphenyl)phenyl]ethanone Show/Hide	C16H16O2	1
1	IC50 = 5400 nM Bioactivity Info	TI LI LO TS
CP0427976 Compound Info	6-(3-ethyl-4-methoxyphenyl)-3,4-dihydro-2H-naphthalen-1-one Show/Hide	C19H20O2	1
1	IC50 = 8300 nM Bioactivity Info	TI LI LO TS
CP0471274 Compound Info	1-[2-ethyl-4-(4-hydroxyphenyl)phenyl]ethanone Show/Hide	C16H16O2	1
1	IC50 = 9900 nM Bioactivity Info	TI LI LO TS
CP0377970 Compound Info	(8R,9S,13S,14S)-3-hydroxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-16-carbonitrile Show/Hide	C19H21NO2	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0433899 Compound Info	6-(4-hydroxyphenyl)-3,4-dihydro-2H-naphthalen-1-one Show/Hide	C16H14O2	1
1	IC50 = 15600 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01014, Cysteine protease CPP32

Protein Info

Protein ID: PT01255, Cytochrome P-450AROM

Protein Info

Protein ID: PT02999, Cytochrome P450 26A1

Protein Info

Protein ID: PT00886, Estrogen receptor

Protein Info

Protein ID: PT00889, Estrogen receptor beta

Protein Info

Protein ID: PT01172, Progesterone receptor

Protein Info

Protein ID: PT06104, Solute carrier family 40 member 1

Protein Info

Protein ID: PT01689, Steryl-sulfatase

Protein Info

Cell Viability or Cytotoxicity Assay

Compound ID	Compound Name	Compound Formula
CP0003433 Compound Info	(Arylindolyl)maleimide deriv. 27 Show/Hide	C21H16N4O2	1
1	GI50 = 2370 nM	TI LI LO TS
CP0003580 Compound Info	Faridak Show/Hide	C21H23N3O2	1
1	IC50 = 6.98 nM	TI LI LO TS
CP0006369 Compound Info	6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile Show/Hide	C32H31N5O3	1
1	GI50 = 4150 nM	TI LI LO TS
CP0007711 Compound Info	(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid Show/Hide	C26H31F3N4O3	1
1	GI50 = 23.9 nM	TI LI LO TS
CP0008405 Compound Info	(2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide Show/Hide	C19H22F3N5O2S	1
1	IC50 = 420 nM	TI LI LO TS
CP0010394 Compound Info	1-(2-chlorophenyl)-3-[4-[4-cyano-5-morpholin-4-yl-2-(1H-1,2,4-triazol-5-yl)thiophen-3-yl]phenyl]urea Show/Hide	C24H20ClN7O2S	1
1	IC50 = 310 nM	TI LI LO TS
CP0016713 Compound Info	2-[(E)-2-(2,6-dichlorophenyl)ethenyl]-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one Show/Hide	C23H21Cl2NO5	1
1	GI50 = 6000 nM	TI LI LO TS
CP0018072 Compound Info	US10662186, Compound 63 Show/Hide	C27H32F2N8	1
1	IC50 = 8.62 nM	TI LI LO TS
CP0019438 Compound Info	8-[3-(1-benzothiophen-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one Show/Hide	C21H20ClN3OS	1
1	GI50 = 17920 nM	TI LI LO TS
CP0019439 Compound Info	8-[3-(1-benzofuran-2-yl)-5-chloropyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one Show/Hide	C21H20ClN3O2	1
1	GI50 = 16180 nM	TI LI LO TS
CP0043589 Compound Info	(13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol Show/Hide	C32H47F5O3S	1
1	IC50 = 3 nM	TI LI LO TS
CP0064592 Compound Info	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate Show/Hide	C47H51NO14	1
1	GI50 = 12.5 nM	TI LI LO TS
CP0071951 Compound Info	(E)-3-[4-[(E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-enyl]phenyl]prop-2-enoic acid Show/Hide	C26H20ClFN2O2	1
1	IC50 = 27 nM	TI LI LO TS
CP0139017 Compound Info	2-[10-(2-methoxyethyl)-13-oxa-3,4,6,7,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7-tetraen-5-yl]-N-(piperidin-4-ylmethyl)quinolin-8-amine Show/Hide	C25H30N8O2	1
1	GI50 = 10800 nM	TI LI LO TS
CP0168495 Compound Info	ethyl 4-[[2-[2-(4-cyanophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoate Show/Hide	C22H18N4O3S	1
1	IC50 = 2180 nM	TI LI LO TS
CP0213915 Compound Info	ethyl 4-[[2-[2-(4-nitrophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoate Show/Hide	C21H18N4O5S	1
1	IC50 = 8090 nM	TI LI LO TS
CP0228522 Compound Info	4-[[4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazin-1-yl]methyl]-N-hydroxybenzamide Show/Hide	C28H26FN5O4	1
1	IC50 > 50000 nM	TI LI LO TS
CP0236214 Compound Info	2-fluoro-N-[2-[4-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenyl]ethyl]-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzamide Show/Hide	C27H23FN4O4	1
1	IC50 = 2140 nM	TI LI LO TS
CP0239959 Compound Info	[(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl]boronic acid Show/Hide	C32H48BF5O4S	1
1	IC50 = 6.1 nM	TI LI LO TS
CP0360699 Compound Info	2-[4-[[4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazin-1-yl]methyl]phenyl]-N-hydroxyacetamide Show/Hide	C29H28FN5O4	1
1	IC50 > 50000 nM	TI LI LO TS
CP0372634 Compound Info	5-(3-Chloro-furan-2-yl)-3-(4-trifluoromethyl-phenyl)-[1,2,4]oxadiazole Show/Hide	C13H6ClF3N2O2	1
1	GI50 = 170 nM	TI LI LO TS
CP0372681 Compound Info	5-Chloro-2-[5-(3-chloro-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-pyridine Show/Hide	C11H5Cl2N3O2	1
1	GI50 = 13000 nM	TI LI LO TS
CP0392290 Compound Info	5-(3-Chloro-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]oxadiazole Show/Hide	C12H6Cl2N2O2	1
1	GI50 = 120 nM	TI LI LO TS
CP0404841 Compound Info	2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5-chloro-pyridine Show/Hide	C11H5BrClN3O2	1
1	GI50 = 380 nM	TI LI LO TS
CP0417920 Compound Info	1-(3-{[(2S)-2-aminopropanamido]methyl}phenyl)-N-[(2-methoxyphenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide Show/Hide	C23H24F3N5O3	1
1	IC50 > 10000 nM	TI LI LO TS
CP0421277 Compound Info	4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-retinamide Show/Hide	C26H32N4O	1
1	IC50 = 9 nM	TI LI LO TS
CP0461497 Compound Info	5-Chloro-2-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-pyridine Show/Hide	C11H5Cl2N3OS	1
1	GI50 = 200 nM	TI LI LO TS
CP0461507 Compound Info	5-(3-Bromo-furan-2-yl)-3-(4-trifluoromethyl-phenyl)-[1,2,4]oxadiazole Show/Hide	C13H6BrF3N2O2	1
1	GI50 = 320 nM	TI LI LO TS
CP0463588 Compound Info	ethyl 4-[[2-[2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl]sulfanylpyrimidin-4-yl]amino]benzoate Show/Hide	C22H18F3N3O3S	1
1	IC50 = 32060 nM	TI LI LO TS
CP0488026 Compound Info	2-[4-(3-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-phenylphenyl)ethanone Show/Hide	C26H21N3O2S	1
1	IC50 = 12050 nM	TI LI LO TS
CP0497086 Compound Info	2-[5-(3-Chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-5-trifluoromethyl-pyridine Show/Hide	C12H5ClF3N3OS	1
1	GI50 = 350 nM	TI LI LO TS
CP0517565 Compound Info	[4-(adamantane-1-carbonylamino)phenyl] sulfamate Show/Hide	C17H22N2O4S	1
1	IC50 = 5780 nM	TI LI LO TS
CP0531331 Compound Info	1-[4-(3-methylphenyl)cyclohexyl]-4-pyridin-3-ylpiperazine Show/Hide	C22H29N3	1
1	IC50 = 25000 nM	TI LI LO TS
CP0534160 Compound Info	5-[[2,5-diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-[(4-methoxyphenyl)methyl]benzamide Show/Hide	C30H38N4O8S	1
1	IC50 = 8310 nM	TI LI LO TS
CP0553152 Compound Info	[4-(1-adamantylcarbamoyl)-2-chlorophenyl] sulfamate Show/Hide	C17H21ClN2O4S	1
1	IC50 = 1040 nM	TI LI LO TS
CP0558414 Compound Info	2-[4-[[(Z)-3-oxo-3-(10H-phenothiazin-2-yl)prop-1-enyl]amino]phenyl]sulfonylguanidine Show/Hide	C22H19N5O3S2	1
1	IC50 = 23700 nM	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Pleural effusion)

Cell Line Name		Organism	Disease
U-937	Cell Line Info	Homo sapiens (Human)	Adult acute monocytic leukemia
SU-DHL-1	Cell Line Info	Homo sapiens (Human)	Anaplastic large cell lymphoma, ALK-positive
SR	Cell Line Info	Homo sapiens (Human)	Anaplastic large cell lymphoma, ALK-positive
MC116	Cell Line Info	Homo sapiens (Human)	B-cell non-Hodgkin lymphoma
K-562	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/A02	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/Adr	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/R7	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/DOX	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
MDA-MB-231	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
MDA-MB-415	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
MDA-MB-468	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
SK-BR-3	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
AU565	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
CAL-51	Cell Line Info	Homo sapiens (Human)	Breast carcinoma
CAL-120	Cell Line Info	Homo sapiens (Human)	Breast carcinoma
DG-75	Cell Line Info	Homo sapiens (Human)	Burkitt lymphoma
SUP-T1	Cell Line Info	Homo sapiens (Human)	Childhood T lymphoblastic lymphoma
Pfeiffer	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
WSU-DLCL2	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
Karpas-422	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
DoHH2	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
KATO III	Cell Line Info	Homo sapiens (Human)	Down syndrome
GIST-T1	Cell Line Info	Homo sapiens (Human)	Gastrointestinal stromal tumor
GIST-5R	Cell Line Info	Homo sapiens (Human)	Gastrointestinal stromal tumor
MZ-CRC-1	Cell Line Info	Homo sapiens (Human)	Hereditary thyroid gland medullary carcinoma
L-428	Cell Line Info	Homo sapiens (Human)	Hodgkin lymphoma
KM-H2	Cell Line Info	Homo sapiens (Human)	Hodgkin lymphoma
MCF-7	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/2a	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
T-47	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7 MX100	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/VP	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7-2a	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
T47D:A18	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MVLN	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF/MX	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/Topo	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/NOD2	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7aro	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/MRP1-M6	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/MRP1-10	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/MRP1-M24	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/NOD1	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7piGST	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7-Y1	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/ADM	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7:WS8	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7-FLV1000	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7-neo/Her2	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7 cl.24	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/DX1	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7-LC3	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
T47D-KBluc	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
Calu-6	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
Calu-3	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
HCC78	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H3122	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H3255	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H2122	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
COR-L105	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H1437	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
HCC4006	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H1792	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
DFCI032	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H1355	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H460	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
U-1810	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
COR-L23/R	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
H460/MX20	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
H460R	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
H69AR	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
NCI-H69	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
GLC-4/ADR	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
STC 1	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
RERF-LC-A1	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
Calu-1	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
HCC95	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
RERF-LC-AI Tet-off	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
NCI-H1650	Cell Line Info	Homo sapiens (Human)	Minimally invasive lung adenocarcinoma
NCI-H1666	Cell Line Info	Homo sapiens (Human)	Minimally invasive lung adenocarcinoma
NCI-H929	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
KMS-11	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
UTMC-2	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
KMS-12-PE	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
NCI-H226	Cell Line Info	Homo sapiens (Human)	Pleural epithelioid mesothelioma
Karpas-1106P	Cell Line Info	Homo sapiens (Human)	Primary mediastinal (thymic) large B-cell lymphoma

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han