General Information of the Cell Line
Cell Line ID
CL000892
Cell Line Name
MCF-7/NOD1
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0031
Tissue Information
Pleural effusion
Disease
Invasive breast carcinoma of no special type (NCIt: C4194)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01446, Interleukin-8
Compound ID Compound Name Compound Formula
CP0068491
1-(4-chlorophenyl)sulfonyl-2-benzimidazolamine
   Show/Hide
C13H10ClN3O2S
 2
1
IC50 = 1460 nM
   TI
   LI
   LO
   TS
2
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CP0194694
3-methyl-8-nitro-7-(phenylmethyl)purine-2,6-dione
   Show/Hide
C13H11N5O4
 2
1
IC50 = 2156 nM
   TI
   LI
   LO
   TS
2
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0372586
(1-besylbenzimidazol-2-yl)amine
   Show/Hide
C13H11N3O2S
 2
1
IC50 = 2410 nM
   TI
   LI
   LO
   TS
2
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CP0385714
1-(4-methoxyphenyl)sulfonyl-2-benzimidazolamine
   Show/Hide
C14H13N3O3S
 2
1
IC50 = 3130 nM
   TI
   LI
   LO
   TS
2
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CP0379980
3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purine-2,6-dione
   Show/Hide
C16H18N4O2S
 2
1
IC50 = 3310 nM
   TI
   LI
   LO
   TS
2
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0047507
7-[(E)-but-2-enyl]-3-methyl-8-(3-phenylpropylsulfanyl)purine-2,6-dione
   Show/Hide
C19H22N4O2S
 2
1
IC50 = 3430 nM
   TI
   LI
   LO
   TS
2
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0380859
3-methyl-7-pentyl-8-(2-phenylethylsulfanyl)purine-2,6-dione
   Show/Hide
C19H24N4O2S
 2
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
2
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0437413
1-[2-(4-chloranylphenoxy)ethyl]benzimidazol-2-amine
   Show/Hide
C15H14ClN3O
 2
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
2
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0379409
1-[(4-chlorophenyl)methyl]-2-benzimidazolamine
   Show/Hide
C14H12ClN3
 2
1
IC50 = 12110 nM
   TI
   LI
   LO
   TS
2
IC50 = 19840 nM
   TI
   LI
   LO
   TS
CP0377810
(5E)-5-[[2-(trifluoromethyl)phenyl]hydrazinylidene]-8-quinolinone
   Show/Hide
C16H10F3N3O
 2
1
IC50 = 19790 nM
   TI
   LI
   LO
   TS
2
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0073137
7-butyl-8-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-1,3-dimethylpurine-2,6-dione
   Show/Hide
C22H29ClN6O2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0360366
7-[(E)-but-2-enyl]-3-methyl-8-(phenylmethylsulfanyl)purine-2,6-dione
   Show/Hide
C17H18N4O2S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0385708
2-(2-amino-1-benzimidazolyl)-1-(4-methoxyphenyl)ethanone
   Show/Hide
C16H15N3O2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0385715
(2-amino-1-benzimidazolyl)-(2,4-dichlorophenyl)methanone
   Show/Hide
C14H9Cl2N3O
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0417548
7-[(E)-but-2-enyl]-8-[(4-chlorobenzyl)thio]-3-methyl-xanthine
   Show/Hide
C17H17ClN4O2S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0426431
3-methyl-8-(3-phenylpropylsulfanyl)-7-prop-2-enyl-purine-2,6-dione
   Show/Hide
C18H20N4O2S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0464450
6-methyl-3-(4-methylphenyl)sulfonyl-1H-benzimidazole-2-thione
   Show/Hide
C15H14N2O2S2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0470629
7-(2-methoxyethyl)-3-methyl-8-(3-phenylpropylsulfanyl)purine-2,6-dione
   Show/Hide
C18H22N4O3S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0471913
3-methyl-8-(3-phenylpropylsulfanyl)-7-propan-2-yl-purine-2,6-dione
   Show/Hide
C18H22N4O2S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0474489
MLS-0281326.0001
   Show/Hide
C17H16ClN3O
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0474490
7-Butyl-3-methyl-8-(2-oxo-2-phenyl-ethylsulfanyl)-3,7-dihydro-purine-2,6-dione
   Show/Hide
C18H20N4O3S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0478231
MLS000107619
   Show/Hide
C19H14ClN3O2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0483358
2-(7-butyl-1,3-dimethyl-2,6-dioxopurin-8-yl)sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
   Show/Hide
C17H23N7O3S2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0494623
2-(1,3-Dimethyl-2,6-dioxo-7-propyl-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-N-(4,5,6,7-tetrahydro-benzothiazol-2-yl)-acetamide
   Show/Hide
C19H24N6O3S2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0499532
7-[(E)-3-chloranylbut-2-enyl]-1,3-dimethyl-8-(2-phenylethylamino)purine-2,6-dione
   Show/Hide
C19H22ClN5O2
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0529913
3-Methyl-8-phenethylsulfanyl-7-propyl-3,7-dihydro-purine-2,6-dione
   Show/Hide
C17H20N4O2S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0142376
(1-tosylbenzimidazol-2-yl)amine
   Show/Hide
C14H13N3O2S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0372480
2-(morpholin-4-ylcarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid
   Show/Hide
C14H18N2O4S
 1
1
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0134147
1-(4-methylphenyl)sulfonylbenzimidazole
   Show/Hide
C14H12N2O2S
 1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CP0378226
(5,6-dimethyl-1-tosyl-benzimidazol-2-yl)amine
   Show/Hide
C16H17N3O2S
 1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
CP0474606
(1-nosylbenzimidazol-2-yl)amine
   Show/Hide
C13H10N4O4S
 1
1
IC50 > 5000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Pleural effusion)
Cell Line Name Organism Disease
U-937 Homo sapiens (Human) Adult acute monocytic leukemia
SU-DHL-1 Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
SR Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
MC116 Homo sapiens (Human) B-cell non-Hodgkin lymphoma
K-562 Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/A02 Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/Adr Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/R7 Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/DOX Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
MDA-MB-231 Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-415 Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-468 Homo sapiens (Human) Breast adenocarcinoma
SK-BR-3 Homo sapiens (Human) Breast adenocarcinoma
AU565 Homo sapiens (Human) Breast adenocarcinoma
CAL-51 Homo sapiens (Human) Breast carcinoma
CAL-120 Homo sapiens (Human) Breast carcinoma
DG-75 Homo sapiens (Human) Burkitt lymphoma
SUP-T1 Homo sapiens (Human) Childhood T lymphoblastic lymphoma
Pfeiffer Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
WSU-DLCL2 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
Karpas-422 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
DoHH2 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
KATO III Homo sapiens (Human) Down syndrome
GIST-T1 Homo sapiens (Human) Gastrointestinal stromal tumor
GIST-5R Homo sapiens (Human) Gastrointestinal stromal tumor
MZ-CRC-1 Homo sapiens (Human) Hereditary thyroid gland medullary carcinoma
L-428 Homo sapiens (Human) Hodgkin lymphoma
KM-H2 Homo sapiens (Human) Hodgkin lymphoma
T-47D Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/2a Homo sapiens (Human) Invasive breast carcinoma of no special type
T-47 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 MX100 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/VP Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-2a Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D:A18 Homo sapiens (Human) Invasive breast carcinoma of no special type
MVLN Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF/MX Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/Topo Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD2 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7aro Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M6 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-10 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M24 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7piGST Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-Y1 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/ADM Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7:WS8 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-FLV1000 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-neo/Her2 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 cl.24 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/DX1 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-LC3 Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D-KBluc Homo sapiens (Human) Invasive breast carcinoma of no special type
Calu-6 Homo sapiens (Human) Lung adenocarcinoma
Calu-3 Homo sapiens (Human) Lung adenocarcinoma
HCC78 Homo sapiens (Human) Lung adenocarcinoma
NCI-H3122 Homo sapiens (Human) Lung adenocarcinoma
NCI-H3255 Homo sapiens (Human) Lung adenocarcinoma
NCI-H2122 Homo sapiens (Human) Lung adenocarcinoma
COR-L105 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1437 Homo sapiens (Human) Lung adenocarcinoma
HCC4006 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1792 Homo sapiens (Human) Lung adenocarcinoma
DFCI032 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1355 Homo sapiens (Human) Lung adenocarcinoma
NCI-H460 Homo sapiens (Human) Lung large cell carcinoma
U-1810 Homo sapiens (Human) Lung large cell carcinoma
COR-L23/R Homo sapiens (Human) Lung large cell carcinoma
H460/MX20 Homo sapiens (Human) Lung large cell carcinoma
H460R Homo sapiens (Human) Lung large cell carcinoma
H69AR Homo sapiens (Human) Lung small cell carcinoma
NCI-H69 Homo sapiens (Human) Lung small cell carcinoma
GLC-4/ADR Homo sapiens (Human) Lung small cell carcinoma
STC 1 Homo sapiens (Human) Lung small cell carcinoma
RERF-LC-A1 Homo sapiens (Human) Lung squamous cell carcinoma
Calu-1 Homo sapiens (Human) Lung squamous cell carcinoma
HCC95 Homo sapiens (Human) Lung squamous cell carcinoma
RERF-LC-AI Tet-off Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1650 Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H1666 Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H929 Homo sapiens (Human) Plasma cell myeloma
KMS-11 Homo sapiens (Human) Plasma cell myeloma
UTMC-2 Homo sapiens (Human) Plasma cell myeloma
KMS-12-PE Homo sapiens (Human) Plasma cell myeloma
NCI-H226 Homo sapiens (Human) Pleural epithelioid mesothelioma
Karpas-1106P Homo sapiens (Human) Primary mediastinal (thymic) large B-cell lymphoma