General Information of the Cell Line
Cell Line ID
CL000916
Cell Line Name
MCF7:WS8
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0031
Tissue Information
Pleural effusion
Disease
Invasive breast carcinoma of no special type (NCIt: C4194)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00886, Estrogen receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0255614
 Compound Info 
1,1-bis(4,4'-hydroxyphenyl)-2-phenylbut-1-ene
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C22H20O2
  1
1
EC50 = 0.015 nM
 Bioactivity Info 
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CP0400010
 Compound Info 
4-[1,1-bis(4-hydroxyphenyl)but-1-en-2-yl]phenol
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C22H20O3
  1
1
EC50 = 0.15 nM
 Bioactivity Info 
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CP0413992
 Compound Info 
[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]-(4-hydroxyphenyl)methanone
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C21H13FO3S
  1
1
EC50 = 0.2 nM
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CP0419159
 Compound Info 
5-(4-ethoxyphenyl)-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-2-ol
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C25H24O2
  1
1
EC50 = 0.3 nM
 Bioactivity Info 
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CP0427128
 Compound Info 
5-(4-methoxyphenyl)-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-2-ol
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C24H22O2
  1
1
EC50 = 0.3 nM
 Bioactivity Info 
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CP0045377
 Compound Info 
3-(4-fluorophenyl)-2-(4-hydroxyphenoxy)-1-benzothiophen-6-ol
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C20H13FO3S
  1
1
EC50 = 0.8 nM
 Bioactivity Info 
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CP0259059
 Compound Info 
cyclohexyl-[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]methanone
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C21H19FO2S
  1
1
EC50 = 1 nM
 Bioactivity Info 
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CP0408037
 Compound Info 
[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-(4-methylphenyl)methanone
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C22H16O3S
  1
1
EC50 = 2.6 nM
 Bioactivity Info 
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CP0433288
 Compound Info 
4-(2-ethoxy-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-5-yl)phenol
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C25H24O2
  1
1
EC50 = 2.7 nM
 Bioactivity Info 
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CP0419160
 Compound Info 
4-(2-methoxy-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-5-yl)phenol
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C24H22O2
  1
1
EC50 = 4 nM
 Bioactivity Info 
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CP0264432
 Compound Info 
[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]-[4-(trifluoromethyl)phenyl]methanone
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C22H12F4O2S
  1
1
EC50 = 5.2 nM
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CP0264430
 Compound Info 
(4-ethynylphenyl)-[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]methanone
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C23H13FO2S
  1
1
EC50 = 5.3 nM
 Bioactivity Info 
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CP0120793
 Compound Info 
2-(4-fluorophenyl)-3-(4-hydroxyphenoxy)-1-benzothiophen-6-ol
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C20H13FO3S
  1
1
EC50 = 6.2 nM
 Bioactivity Info 
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CP0159062
 Compound Info 
cyclopropyl-[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]methanone
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C18H13FO2S
  1
1
EC50 = 13.9 nM
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CP0427130
 Compound Info 
4-[2-[2-(dimethylamino)ethoxy]-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-5-yl]phenol
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C27H29NO2
  1
1
EC50 = 15 nM
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CP0362189
 Compound Info 
(4-fluorophenyl)-[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]methanone
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C21H12F2O2S
  1
1
EC50 = 18.5 nM
 Bioactivity Info 
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CP0440063
 Compound Info 
4-[2-[2-(methylamino)ethoxy]-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-5-yl]phenol
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C26H27NO2
  1
1
EC50 = 20 nM
 Bioactivity Info 
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CP0203917
 Compound Info 
[4-(dimethylamino)phenyl]-[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]methanone
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C23H18FNO2S
  1
1
EC50 = 30.6 nM
 Bioactivity Info 
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CP0362190
 Compound Info 
2-(3,4-difluorophenoxy)-3-(4-fluorophenyl)-1-benzothiophen-6-ol
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C20H11F3O2S
  1
1
EC50 = 33.4 nM
 Bioactivity Info 
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CP0408038
 Compound Info 
2-(4-fluorophenoxy)-3-(4-fluorophenyl)-1-benzothiophen-6-ol
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C20H12F2O2S
  1
1
EC50 = 36.8 nM
 Bioactivity Info 
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CP0538416
 Compound Info 
4-[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophene-2-carbonyl]benzonitrile
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C22H12FNO2S
  1
1
EC50 = 58.7 nM
 Bioactivity Info 
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CP0203916
 Compound Info 
[2-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-3-yl]-[4-(trifluoromethyl)phenyl]methanone
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C22H12F4O2S
  1
1
EC50 = 61.5 nM
 Bioactivity Info 
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CP0376340
 Compound Info 
2-(4-chlorophenoxy)-3-(4-fluorophenyl)-1-benzothiophen-6-ol
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C20H12ClFO2S
  1
1
EC50 = 76.1 nM
 Bioactivity Info 
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CP0159061
 Compound Info 
[2-(4-chlorophenyl)-6-hydroxy-1-benzothiophen-3-yl]-[4-(trifluoromethyl)phenyl]methanone
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C22H12ClF3O2S
  1
1
EC50 = 121 nM
 Bioactivity Info 
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CP0109552
 Compound Info 
[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]-(4-methylsulfonylphenyl)methanone
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C22H15FO4S2
  1
1
EC50 = 436.2 nM
 Bioactivity Info 
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CP0109553
 Compound Info 
[3-(4-fluorophenyl)-6-hydroxy-1-benzothiophen-2-yl]-(4-methylphenyl)methanone
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C22H15FO2S
  1
1
EC50 = 717.1 nM
 Bioactivity Info 
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CP0462307
 Compound Info 
[6-hydroxy-3-[4-[2-(3-methylazetidin-1-yl)ethoxy]phenoxy]-1-benzothiophen-2-yl]-(2-methylphenyl)methanone
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C28H27NO4S
  2
1
IC50 = 0.257 nM
 Bioactivity Info 
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2
IC50 = 1.9 nM
 Bioactivity Info 
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CP0471919
 Compound Info 
[3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6-hydroxy-1-benzothiophen-2-yl]-phenylmethanone
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C27H24FNO4S
  2
1
IC50 = 0.5 nM
 Bioactivity Info 
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2
IC50 = 0.7079 nM
 Bioactivity Info 
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CP0519199
 Compound Info 
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(2-methylphenyl)methanone
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C28H26FNO4S
  2
1
IC50 = 0.955 nM
 Bioactivity Info 
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2
IC50 = 1.5 nM
 Bioactivity Info 
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CP0473848
 Compound Info 
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-phenylmethanone
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C27H24FNO4S
  2
1
IC50 = 1.023 nM
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2
IC50 = 4.3 nM
 Bioactivity Info 
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CP0474185
 Compound Info 
(4-fluoro-2,6-dimethylphenyl)-[3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6-hydroxy-1-benzothiophen-2-yl]methanone
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C29H27F2NO4S
  2
1
IC50 = 1.023 nM
 Bioactivity Info 
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2
IC50 = 3.1 nM
 Bioactivity Info 
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CP0471918
 Compound Info 
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(4-fluorophenyl)methanone
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C27H23F2NO4S
  2
1
IC50 = 1.23 nM
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2
IC50 = 28 nM
 Bioactivity Info 
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CP0519202
 Compound Info 
(4-fluoro-2,6-dimethylphenyl)-[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]methanone
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C29H27F2NO4S
  2
1
IC50 = 1.413 nM
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2
IC50 = 3.5 nM
 Bioactivity Info 
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CP0459295
 Compound Info 
(2,4-dimethylphenyl)-[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]methanone
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C29H28FNO4S
  2
1
IC50 = 1.445 nM
 Bioactivity Info 
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2
IC50 = 7.4 nM
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CP0043589
 Compound Info 
(13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pentane-1-sulfinyl)-nonyl]-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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C32H47F5O3S
  1
1
IC50 = 1.585 nM
 Bioactivity Info 
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CP0554767
 Compound Info 
[3-[4-[2-(azetidin-1-yl)ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(2-methylphenyl)methanone
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C27H25NO4S
  1
1
IC50 = 1.905 nM
 Bioactivity Info 
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CP0462305
 Compound Info 
[3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(2-methylphenyl)methanone
   Show/Hide
C28H26FNO4S
  2
1
IC50 = 2.1 nM
 Bioactivity Info 
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2
IC50 = 2.57 nM
 Bioactivity Info 
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CP0519200
 Compound Info 
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(4-fluoro-2-methylphenyl)methanone
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C28H25F2NO4S
  2
1
IC50 = 2.7 nM
 Bioactivity Info 
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2
IC50 = 3.631 nM
 Bioactivity Info 
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CP0427129
 Compound Info 
2-[4-(2-ethoxy-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-5-yl)phenoxy]-N,N-dimethylethanamine
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C29H33NO2
  1
1
IC50 = 3 nM
 Bioactivity Info 
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CP0433287
 Compound Info 
5-[4-[2-(methylamino)ethoxy]phenyl]-6-phenyl-8,9-dihydro-7H-benzo[7]annulen-2-ol
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C26H27NO2
  1
1
IC50 = 3 nM
 Bioactivity Info 
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CP0459294
 Compound Info 
(4-fluoro-2,6-dimethylphenyl)-[3-[4-[2-[(3S)-3-(fluoromethyl)pyrrolidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]methanone
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C30H29F2NO4S
  1
1
IC50 = 3.02 nM
 Bioactivity Info 
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CP0529673
 Compound Info 
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(4-hydroxy-2-methylphenyl)methanone
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C28H26FNO5S
  2
1
IC50 = 5.129 nM
 Bioactivity Info 
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2
IC50 = 14 nM
 Bioactivity Info 
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CP0519197
 Compound Info 
(4-fluoro-2-methylphenyl)-[3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6-hydroxy-1-benzothiophen-2-yl]methanone
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C28H25F2NO4S
  2
1
IC50 = 5.2 nM
 Bioactivity Info 
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2
IC50 = 9.333 nM
 Bioactivity Info 
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CP0462306
 Compound Info 
[3-[4-(1-cyclopropylazetidin-3-yl)oxyphenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(4-fluoro-2,6-dimethylphenyl)methanone
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C29H26FNO4S
  2
1
IC50 = 5.888 nM
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2
IC50 = 11 nM
 Bioactivity Info 
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CP0529674
 Compound Info 
(4-fluoro-2,6-dimethylphenyl)-[3-[4-[2-[(3R)-3-(fluoromethyl)pyrrolidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]methanone
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C30H29F2NO4S
  2
1
IC50 = 5.888 nM
 Bioactivity Info 
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2
IC50 = 12 nM
 Bioactivity Info 
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CP0519201
 Compound Info 
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(4-hydroxyphenyl)methanone
   Show/Hide
C27H24FNO5S
  2
1
IC50 = 8.128 nM
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2
IC50 = 64 nM
 Bioactivity Info 
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CP0542318
 Compound Info 
[3-[4-[2-[(3R)-3-(fluoromethyl)pyrrolidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(2-methylphenyl)methanone
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C29H28FNO4S
  1
1
IC50 = 10.47 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Pleural effusion)
Cell Line Name Organism Disease
U-937
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
SU-DHL-1
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
SR
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
MC116
 Cell Line Info 
Homo sapiens (Human) B-cell non-Hodgkin lymphoma
K-562
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/A02
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/Adr
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/R7
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/DOX
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
MDA-MB-231
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-415
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-468
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
SK-BR-3
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
AU565
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
CAL-51
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
CAL-120
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
DG-75
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
SUP-T1
 Cell Line Info 
Homo sapiens (Human) Childhood T lymphoblastic lymphoma
Pfeiffer
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
WSU-DLCL2
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
Karpas-422
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
DoHH2
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
KATO III
 Cell Line Info 
Homo sapiens (Human) Down syndrome
GIST-T1
 Cell Line Info 
Homo sapiens (Human) Gastrointestinal stromal tumor
GIST-5R
 Cell Line Info 
Homo sapiens (Human) Gastrointestinal stromal tumor
MZ-CRC-1
 Cell Line Info 
Homo sapiens (Human) Hereditary thyroid gland medullary carcinoma
L-428
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
KM-H2
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
T-47D
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/2a
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
T-47
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 MX100
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/VP
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-2a
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D:A18
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MVLN
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF/MX
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/Topo
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD2
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7aro
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M6
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-10
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M24
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7piGST
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-Y1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/ADM
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-FLV1000
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-neo/Her2
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 cl.24
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/DX1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-LC3
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D-KBluc
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
Calu-6
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
Calu-3
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC78
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H3122
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H3255
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2122
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
COR-L105
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1437
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC4006
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1792
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
DFCI032
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1355
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H460
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
U-1810
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
COR-L23/R
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
H460/MX20
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
H460R
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
H69AR
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H69
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
GLC-4/ADR
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
STC 1
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
RERF-LC-A1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
Calu-1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
HCC95
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
RERF-LC-AI Tet-off
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1650
 Cell Line Info 
Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H1666
 Cell Line Info 
Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H929
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-11
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
UTMC-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-12-PE
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
NCI-H226
 Cell Line Info 
Homo sapiens (Human) Pleural epithelioid mesothelioma
Karpas-1106P
 Cell Line Info 
Homo sapiens (Human) Primary mediastinal (thymic) large B-cell lymphoma