(R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

AZD-9291

IBRUTINIB

3-[4-(3-bromoanilino)-6-methoxyquinazolin-7-yl]oxypropyl 3-(prop-2-enyldisulfanyl)propanoate

2-But-3-enyldisulfanyl-N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]-acetamide

N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-but-3-enyldisulfanyl-acetamide

3-Allyldisulfanyl-propionic acid 3-[4-(4-bromo-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propyl ester

4-(4-{3-[4-(4-Bromo-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

4-(4-{3-[6-Methoxy-4-(4-nitro-phenylamino)-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

4-(4-{3-[4-(3-Bromo-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

N-[4-(3-Chloro-4-fluoro-phenylamino)-quinazolin-6-yl]-2-[4-(3-oxo-3H-[1,2]dithiol-4-yl)-phenoxy]-acetamide

4-(4-{3-[6-Methoxy-4-(3-trifluoromethyl-phenylamino)-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

4-(4-{3-[4-(3,4-Dimethoxy-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

(R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

4-(4-{3-[4-(3-Chloro-4-fluoro-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

(R)-4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 3-(Dimethylamino)pyrrolidine-1-carboxylate

N-(3-Chloro-2-fluorophenyl)-7-methoxy-6-morpholinoquinazolin-4-amine

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-morpholinoquinazolin-4-amine

N-[(3R,4R)-4-fluoro-1-[6-[(1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

N-[(3R,4R)-1-[6-[(1-ethyl-3-methoxypyrazol-4-yl)amino]-9-methylpurin-2-yl]-4-fluoropyrrolidin-3-yl]prop-2-enamide

(1S,4S)-4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 5-Methyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

N-[1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]-7-methylbenzimidazol-2-yl]-2-(trifluoromethyl)pyridine-4-carboxamide

(S)-4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl3-(Dimethylamino)pyrrolidine-1-carboxylate

N-[1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]-7-methylbenzimidazol-2-yl]-2-methylpyridine-4-carboxamide

4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl Morpholine-4-carboxylate

N-[(3R,4R)-4-fluoro-1-[6-[[3-methoxy-1-(1-methylpyrrolidin-3-yl)pyrazol-4-yl]amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 4-Methylpiperazine-1-carboxylate

N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide

N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine

N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(morpholin-4-ylmethyl)quinazolin-4-amine

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl (2S)-2,4-Dimethylpiperazine-1-carboxylate

N-[(3S)-1-[9-(2-hydroxyethyl)-6-[4-(4-methylpiperazin-1-yl)anilino]purin-2-yl]pyrrolidin-3-yl]prop-2-enamide

[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2,4-dimethylpiperazine-1-carboxylate

1-[(3aS,6aR)-2-[6-[4-(4-methylpiperazin-1-yl)anilino]-9-propan-2-ylpurin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]prop-2-en-1-one

AVL-301

N-[7-methyl-1-[(3R)-1-prop-2-enoylazepan-3-yl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide

2-[4-(difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]phenyl]ethynyl]-7-methylindazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-N-(1,3-thiazol-2-yl)acetamide

(S)-4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 3,4-Dimethylpiperazine-1-carboxylate

(R)-4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 3,4-dimethylpiperazine-1-carboxylate

N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine

N-[1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]-7-methylbenzimidazol-2-yl]-3-(trifluoromethyl)benzamide

N-[5-methyl-1-(1-prop-2-enoylazepan-3-yl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide

(4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl)-(morpholino)methanone

N-[5-methyl-1-(1-prop-2-enoylpiperidin-3-yl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide

2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide

N-[5-methyl-1-[3-[methyl(prop-2-enoyl)amino]phenyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide

N-[5-methyl-1-[3-(prop-2-enoylamino)phenyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide

N-[5-methyl-1-[3-(prop-2-enoylamino)propyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide