Brief Information of the Compound and Protein
Compound Name
(S)-4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 3,4-Dimethylpiperazine-1-carboxylate
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PubChem ID
CID: 122192392
Canonical SMILES
COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC(=O)N1CCN(C)[C@@H](C)C1
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Compound Formula C22H23ClFN5O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000324 NCI-H3255 Homo sapiens (Human)  1
1
IC50 = 16.9 nM
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