| Compound ID |
Compound Name |
Compound Formula |
|
CP0038642
|
5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide, 14
Show/Hide
|
C23H24FN5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0421275
|
N-[(2S)-1-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]-1H-indole-2-carboxamide
Show/Hide
|
C26H29FN4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0398751
|
(2S)-N-[2-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C24H27ClN4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0474556
|
N-[(1S)-2-[4-(6-fluoro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C26H27FN4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0374231
|
N-[2-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-4-chlorobenzamide
Show/Hide
|
C21H22BrClN4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0474558
|
N-[(1S)-2-[4-(5-chloro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-3,4-difluoro-benzamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C22H23ClF2N4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0374236
|
N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-3,4-difluoro-benzamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C22H23BrF2N4O2
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0143509
|
(1R,2R)-N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-phenyl-cyclopropanecarboxamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C25H29BrN4O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0374230
|
N-[2-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-4-fluorobenzamide
Show/Hide
|
C21H22BrFN4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0398753
|
N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-4-chloro-benzamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C22H24BrClN4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0440703
|
3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide
Show/Hide
|
C21H21F3N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0455920
|
N-[2-[4-(5-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C25H25FN4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0398756
|
N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C26H27BrN4O2
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0086302
|
4-bromo-N-[(2S)-1-[1-(3-methylphenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
|
C24H29BrN4O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0136333
|
4-Chloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 50
Show/Hide
|
C21H23ClN4O2
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0522711
|
4-chloranyl-N-[(2S)-1-[4-(5-chloranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0536743
|
4-chloro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide
Show/Hide
|
C21H22ClFN4O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0423544
|
4-chloranyl-N-[(2S)-1-[4-(5-fluoranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24ClFN4O2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0336940
|
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0398754
|
(1R,2R)-N-[(1S)-2-[4-(5-chloro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-phenyl-cyclopropanecarboxamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C25H29ClN4O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0297516
|
4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)furan-2-carboxamide, 64
Show/Hide
|
C19H20Br2N4O3
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0398762
|
N-[(1S)-2-[4-(5-chloro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-4-fluoro-benzamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C22H24ClFN4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0465471
|
N-[2-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-4-methylbenzamide
Show/Hide
|
C22H25ClN4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0507935
|
N-[(1S)-2-[1-(3-fluorophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]-1-methyl-ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C27H29FN4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0462590
|
4-fluoranyl-N-[(2S)-1-[4-(5-fluoranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24F2N4O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0228146
|
(S)-N-(1-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)-2-naphthamide, 69
Show/Hide
|
C26H27ClN4O2
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 46 nM
|
|
|
|
CP0445166
|
4-fluoro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide
Show/Hide
|
C21H22F2N4O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0474561
|
(1R,2R)-N-[(1S)-2-[4-(6-fluoro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-phenyl-cyclopropanecarboxamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0144408
|
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C23H24N4O2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0421274
|
N-[(2S)-1-[(4R)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]-1H-indole-2-carboxamide
Show/Hide
|
C26H29FN4O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0421276
|
N-[(2S)-1-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]-3-phenylprop-2-ynamide
Show/Hide
|
C26H28FN3O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0136326
|
3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 47
Show/Hide
|
C21H22F2N4O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0374228
|
4-chloro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide
Show/Hide
|
C21H22ClFN4O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0038644
|
3,4-Dichloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 48
Show/Hide
|
C21H22Cl2N4O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0228121
|
9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-9H-fluorene-4-carboxamide, 57
Show/Hide
|
C28H26N4O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0419612
|
4-fluoro-N-[(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
|
C23H26F2N4O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0136322
|
N-[2-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-4-fluorobenzamide
Show/Hide
|
C21H22ClFN4O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0238288
|
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0920984
|
3,4-difluoro-N-(2-(3-fluoro-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide
Show/Hide
|
C21H21F3N4O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0922188
|
Rac-N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl)-1H-indole-2-carboxamide
Show/Hide
|
C25H29N5O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0521140
|
N-[2-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H27FN4O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0228470
|
CID21428857
Show/Hide
|
C19H22N4O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0424925
|
N-[(1S)-2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-methyl-ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0519310
|
N-[(2S)-1-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]quinoline-3-carboxamide
Show/Hide
|
C27H29FN4O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0136331
|
4-Methyl-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 52
Show/Hide
|
C22H26N4O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0234014
|
(1R,2R)-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-phenylcyclopropanecarboxamide, 58
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0957723
|
Rac-5-fluoro-N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl)-1H-indole-2-carboxamide
Show/Hide
|
C25H28FN5O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0240265
|
CID25105709
Show/Hide
|
C19H23N5O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0374227
|
3,4-bis(fluoranyl)-N-[(2S)-1-[4-(4-fluoranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H23F3N4O2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0474557
|
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-3-phenylprop-2-ynamide
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0423545
|
4-chloranyl-N-[(2S)-1-[4-(4-fluoranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24ClFN4O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0240263
|
4-Fluoro-N-(4-fluorobenzoyl)-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 66
Show/Hide
|
C28H26F2N4O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0038636
|
3,4,5-Trimethoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 55
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0374233
|
N-[(1S)-2-[4-(4-fluoro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C26H27FN4O2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0374229
|
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]quinoline-6-carboxamide
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0904840
|
N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)-1H-indole-2-carboxamide
Show/Hide
|
C25H27N5O2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0434228
|
4-bromo-N-[(2R)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
|
C23H26BrFN4O2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0038649
|
CID25105702
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0268921
|
3,5-Dichloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 49
Show/Hide
|
C21H22Cl2N4O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0396587
|
3,4-difluoro-N-[(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
|
C23H25F3N4O2
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0493781
|
(1R,2R)-N-[(1S)-2-[4-(4-fluoro-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-phenyl-cyclopropanecarboxamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0374232
|
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1,4-dihydronaphthalene-2-carboxamide
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0963742
|
(trans)-N-(2-(2-methyl-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-phenylcyclopropanecarboxamide
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0517516
|
6-fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide
Show/Hide
|
C25H25FN4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0526191
|
4-fluoranyl-N-[(2S)-1-[4-(4-fluoranyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24F2N4O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0424926
|
3,4-bis(fluoranyl)-N-[(2S)-1-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C23H26F2N4O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0503076
|
N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H26N4O2S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0468781
|
US9127005, P0L
Show/Hide
|
C27H29FN4O2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0507536
|
5-fluoranyl-N-[2-[1-(3-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C24H25F2N5O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0481699
|
4-bromo-N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl]benzamide
Show/Hide
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C23H27BrN4O2
|
1
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| 1 |
IC50 = 230 nM
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CP0957724
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5-fluoro-N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)-1H-indole-2-carboxamide
Show/Hide
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C25H26FN5O2
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1
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| 1 |
IC50 = 230 nM
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CP0858428
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N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)-2-naphthamide
Show/Hide
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C27H28N4O2
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1
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| 1 |
IC50 = 244 nM
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CP0402137
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N-[2-[1-(3-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide
Show/Hide
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C24H25ClFN5O2
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1
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| 1 |
IC50 = 250 nM
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CP0471739
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4-fluoro-N-[(2S)-1-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
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C24H27F2N3O2
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1
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| 1 |
IC50 = 250 nM
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CP0384198
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5-fluoranyl-N-[2-[1-(4-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
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C24H25F2N5O2
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1
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| 1 |
IC50 = 290 nM
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CP0508298
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N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl]naphthalene-2-carboxamide
Show/Hide
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C27H30N4O2
|
1
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| 1 |
IC50 = 315 nM
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CP0533776
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N-[2-[(4R)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide
Show/Hide
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C25H27FN4O2
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1
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| 1 |
IC50 = 320 nM
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CP0557314
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N-[(2S)-1-[(4R)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]-3-phenylprop-2-ynamide
Show/Hide
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C26H28FN3O2
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1
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| 1 |
IC50 = 320 nM
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CP0125380
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CID25105707
Show/Hide
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C27H27N5O2
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1
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| 1 |
IC50 = 330 nM
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CP0371703
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N-[2-[1-(4-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide
Show/Hide
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C24H25ClFN5O2
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1
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| 1 |
IC50 = 335 nM
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CP0216108
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CID25105708
Show/Hide
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C22H26N4O2S
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1
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| 1 |
IC50 = 380 nM
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CP0402135
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N-[2-[1-(3,4-difluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide
Show/Hide
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C24H24F3N5O2
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1
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| 1 |
IC50 = 390 nM
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CP0897028
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4-bromo-N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)benzamide
Show/Hide
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C23H25BrN4O2
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1
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| 1 |
IC50 = 468 nM
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CP0922190
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4-fluoro-N-(2-(2-methyl-4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide
Show/Hide
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C22H25FN4O2
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1
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| 1 |
IC50 = 636 nM
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CP0396586
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4-fluoro-N-[(2R)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
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C23H26F2N4O2
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1
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| 1 |
IC50 = 760 nM
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CP0946025
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3,4-difluoro-N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)benzamide
Show/Hide
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C23H24F2N4O2
|
1
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| 1 |
IC50 = 820 nM
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CP0575128
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N-[(2S)-1-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]propan-2-yl]naphthalene-2-carboxamide
Show/Hide
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C28H30FN3O2
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1
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| 1 |
IC50 = 820 nM
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CP0238366
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2-Chloro-N-(2-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 68
Show/Hide
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C21H22Cl2N4O2
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1
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| 1 |
IC50 = 870 nM
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CP0477516
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N-[2-[1-(3-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
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C25H26ClN5O2
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1
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| 1 |
IC50 = 870 nM
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CP0921003
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4-fluoro-N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)benzamide
Show/Hide
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C23H25FN4O2
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1
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| 1 |
IC50 = 870 nM
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CP0238293
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N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
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C26H28N4O2
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1
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| 1 |
IC50 = 1000 nM
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CP0293764
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4-Methoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)benzamide, 51
Show/Hide
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C22H26N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0556358
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3,4-difluoro-N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl]benzamide
Show/Hide
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C23H26F2N4O2
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1
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| 1 |
IC50 = 1080 nM
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CP0922189
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(trans)-N-(2-(5-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)ethyl)-2-phenylcyclopropanecarboxamide
Show/Hide
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C26H30N4O2
|
1
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| 1 |
IC50 = 1080 nM
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CP0489457
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N-[2-[1-(3-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
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C26H27ClN4O2
|
1
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| 1 |
IC50 = 1200 nM
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CP0439922
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N-[2-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]ethyl]-3-phenylprop-2-ynamide
Show/Hide
|
C25H26FN3O2
|
1
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| 1 |
IC50 = 1200 nM
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CP0521139
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N-[2-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C26H27FN4O2
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1
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| 1 |
IC50 = 1350 nM
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CP0419613
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3,4-difluoro-N-[(2R)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Show/Hide
|
C23H25F3N4O2
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1
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| 1 |
IC50 = 1400 nM
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CP0508297
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4-fluoro-N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl]benzamide
Show/Hide
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C23H27FN4O2
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1
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| 1 |
IC50 = 1490 nM
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CP0267179
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N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C26H27FN4O2
|
1
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| 1 |
IC50 = 1500 nM
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CP0428098
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4-bromo-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide
Show/Hide
|
C22H24BrFN4O2
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1
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| 1 |
IC50 = 1540 nM
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CP0477518
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N-[2-[1-(4-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C26H27FN4O2
|
1
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| 1 |
IC50 = 1700 nM
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CP0451901
|
US9127005, NGH
Show/Hide
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C24H27F2N3O2
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1
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| 1 |
IC50 = 1700 nM
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CP0140910
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N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-2-carboxamide
Show/Hide
|
C25H27N5O2
|
1
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| 1 |
IC50 = 1900 nM
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CP0489455
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N-[2-[1-(4-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C25H26FN5O2
|
1
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| 1 |
IC50 = 2000 nM
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CP0477517
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N-[2-[1-(3,4-difluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C25H25F2N5O2
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1
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| 1 |
IC50 = 2060 nM
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CP0452544
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N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenylprop-2-ynamide
Show/Hide
|
C24H26N4O2
|
1
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| 1 |
IC50 = 2100 nM
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CP0523868
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N-[2-[1-(4-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
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C26H27ClN4O2
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1
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| 1 |
IC50 = 2270 nM
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CP0507538
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N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C25H26FN5O2
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1
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| 1 |
IC50 = 2500 nM
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CP0452545
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(trans)-N-((S)-1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl)-2-phenylcyclopropanecarboxamide
Show/Hide
|
C26H32N4O2
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1
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| 1 |
IC50 = 2600 nM
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CP0427790
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N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-5-fluoro-1H-indole-2-carboxamide
Show/Hide
|
C24H25BrFN5O2
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1
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| 1 |
IC50 = 2660 nM
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CP0402142
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N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C25H26BrN5O2
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1
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| 1 |
IC50 = 2700 nM
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CP0502780
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N-[2-[1-(3,4-difluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C26H26F2N4O2
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1
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| 1 |
IC50 = 2800 nM
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CP0526629
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3-methyl-N-[(2S)-1-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C24H30N4O2
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1
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| 1 |
IC50 = 3400 nM
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CP0234018
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4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamide, 82
Show/Hide
|
C29H28Cl2N4O3
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1
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| 1 |
IC50 = 3400 nM
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CP0434813
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N-[2-[1-(3-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluorobenzamide
Show/Hide
|
C22H24ClFN4O2
|
1
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| 1 |
IC50 = 3470 nM
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CP0415349
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N-[2-[1-(4-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]quinoline-3-carboxamide
Show/Hide
|
C25H26ClN5O2
|
1
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| 1 |
IC50 = 3500 nM
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CP0067906
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1-(2-pyridyl)piperazine
Show/Hide
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C9H13N3
|
1
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| 1 |
IC50 = 3600 nM
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CP0434705
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1-(pyridin-4-yl)piperazine
Show/Hide
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C9H13N3
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1
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| 1 |
IC50 = 3600 nM
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CP0517406
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N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-1,2,3,4-tetrahydronaphthalene-2-carboxamide
Show/Hide
|
C26H32N4O2
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1
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| 1 |
IC50 = 4250 nM
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CP0648741
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4-Hydroxytamoxifen
Show/Hide
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C26H29NO2
|
1
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| 1 |
IC50 = 4800 nM
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CP0470770
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4-fluoro-N-[2-[(4S)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]ethyl]benzamide
Show/Hide
|
C23H25F2N3O2
|
1
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| 1 |
IC50 = 5500 nM
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CP0497216
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N-[2-[1-(4-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluorobenzamide
Show/Hide
|
C22H24ClFN4O2
|
1
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| 1 |
IC50 = 5590 nM
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CP0502781
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N-[2-[1-(3,4-difluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluorobenzamide
Show/Hide
|
C22H23F3N4O2
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1
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| 1 |
IC50 = 5780 nM
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CP0424927
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4-amino-3-methoxy-N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]benzamide;2,2,2-trifluoroacetic acid
Show/Hide
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C23H29N5O3
|
1
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| 1 |
IC50 = 5900 nM
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CP0373641
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N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C26H27BrN4O2
|
1
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| 1 |
IC50 = 5900 nM
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CP0038641
|
CID25105696
Show/Hide
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C22H34N4O2
|
1
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| 1 |
IC50 = 6000 nM
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CP0471740
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N-[2-[(4R)-4-(4-fluorophenyl)-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]ethyl]-3-phenylprop-2-ynamide
Show/Hide
|
C25H26FN3O2
|
1
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| 1 |
IC50 = 6400 nM
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CP0041761
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2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol
Show/Hide
|
C28H27NO4S
|
1
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| 1 |
IC50 = 8500 nM
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CP0427789
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N-[2-[1-(4-bromophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluorobenzamide
Show/Hide
|
C22H24BrFN4O2
|
1
|
| 1 |
IC50 = 10000 nM
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CP0415353
|
4-fluoranyl-N-[2-[1-(3-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24F2N4O2
|
2
|
| 1 |
IC50 = 11800 nM
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| 2 |
IC50 = 12000 nM
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CP0468373
|
US9127005, CTH Racemic mixture
Show/Hide
|
C26H27FN4O2
|
1
|
| 1 |
IC50 = 12000 nM
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CP0507916
|
4-fluoranyl-N-[2-[1-(4-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H24F2N4O2
|
1
|
| 1 |
IC50 = 14000 nM
|
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CP0422300
|
N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoxaline-2-carboxamide
Show/Hide
|
C24H26N6O2
|
1
|
| 1 |
IC50 > 20000 nM
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CP0435029
|
(trans)-N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-phenylcyclopropanecarboxamide
Show/Hide
|
C25H30N4O2
|
1
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| 1 |
IC50 > 20000 nM
|
|
|
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CP0216109
|
CID25105697
Show/Hide
|
C30H50N4O2
|
1
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| 1 |
IC50 > 20000 nM
|
|
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CP0145932
|
3,4-bis(fluoranyl)-N-[2-[1-(3-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid
Show/Hide
|
C22H23F3N4O2
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
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CP0519245
|
US9127005, NFW
Show/Hide
|
C23H25F2N3O2
|
1
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| 1 |
IC50 > 20000 nM
|
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|
