General Information of the Cell Line
Cell Line ID
CL000187
Cell Line Name
Calu-6
Synonyms
CaLu-6
CALU-6
Calu.6
Calu 6
Calu6
CALU6
CaLu-06
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0236
Tissue Information
Pleural effusion
Disease
Lung adenocarcinoma (NCIt: C3512)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02585, Proteasome subunit beta type-5
 Protein Info 
Compound ID Compound Name Compound Formula
CP0004620
 Compound Info 
(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid
   Show/Hide
C19H25BN4O4
  1
1
IC50 = 3.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0034167
 Compound Info 
[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
   Show/Hide
C14H19BCl2N2O4
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0112227
 Compound Info 
(2S)-N-[(2S)-1-[(2-chlorophenyl)methylamino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-N'-(2,2-dimethylpropyl)-2-[[2-(1H-indol-3-yl)-2-oxoacetyl]amino]butanediamide
   Show/Hide
C34H37ClN6O5
  1
1
IC50 = 9.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849436
 Compound Info 
(S)-2-(2-(1H-indol-3-yl)-2-oxoacetamido)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentylsuccinamide
   Show/Hide
C36H41N5O5
  1
1
IC50 = 9.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0755326
 Compound Info 
(S)-2-(2-(1H-indol-3-yl)-2-oxoacetamido)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentylsuccinamide
   Show/Hide
C36H40ClN5O5
  1
1
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0923548
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-2-(4-(benzyloxy)benzamido)-N4-neopentylsuccinamide
   Show/Hide
C40H46N4O5
  1
1
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0864842
 Compound Info 
(S)-2-(4-(benzyloxy)benzamido)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentylsuccinamide
   Show/Hide
C40H45ClN4O5
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0755327
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-4-phenylbutan-2-yl)-2-(5-methylisoxazole-3-carboxamido)-N4-neopentylsuccinamide
   Show/Hide
C31H38ClN5O5
  1
1
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849438
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentyl-2-(3-phenylpropanamido)succinamide
   Show/Hide
C35H44N4O4
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0880261
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentyl-2-(3-phenylpropanamido)succinamide
   Show/Hide
C35H43ClN4O4
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849440
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-3-(pyridin-3-yl)propan-2-yl)-N4-neopentyl-2-(3-phenylpropanamido)succinamide
   Show/Hide
C33H40ClN5O4
  1
1
IC50 = 24 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0881290
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-2-(5-methylisoxazole-3-carboxamido)-N2-neopentylsuccinamide
   Show/Hide
C31H39N5O5
  1
1
IC50 = 25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849435
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentyl-2-(2-(piperidin-1-yl)acetamido)succinamide
   Show/Hide
C33H47N5O4
  1
1
IC50 = 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0881288
 Compound Info 
(S)-2-((S)-2-(2-(1H-indol-3-yl)-2-oxoacetamido)-3-(3-tert-butyl-1,2,4-oxadiazol-5-yl)propanamido)-N-(4-methylbenzyl)-4-phenylbutanamide
   Show/Hide
C37H40N6O5
  1
1
IC50 = 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849434
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxopropan-2-yl)-N4-neopentyl-2-(3-phenylpropanamido)succinamide
   Show/Hide
C28H37ClN4O4
  1
1
IC50 = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0877531
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-2-(4-tert-butylbenzamido)-N4-neopentylsuccinamide
   Show/Hide
C37H48N4O4
  1
1
IC50 = 40 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0647535
 Compound Info 
5-methyl-N-((S)-1-((S)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxo-4-phenylbutan-2-yl)pyrazine-2-carboxamide
   Show/Hide
C44H48N6O4
  1
1
IC50 = 53 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0867343
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-2-(2-(4-fluorophenyl)acetamido)-N4-neopentylsuccinamide
   Show/Hide
C34H41FN4O4
  1
1
IC50 = 73 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849433
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-4-phenylbutan-2-yl)-2-(2-(4-fluorophenyl)acetamido)-N4-neopentylsuccinamide
   Show/Hide
C34H40ClFN4O4
  1
1
IC50 = 85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0856343
 Compound Info 
(S)-N1-((S)-1-(cyclopropylmethylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentyl-2-(3-phenylpropanamido)succinamide
   Show/Hide
C32H44N4O4
  1
1
IC50 = 360 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849437
 Compound Info 
(S)-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentyl-2-pivalamidosuccinamide
   Show/Hide
C31H44N4O4
  1
1
IC50 = 610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849441
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-3-(pyridin-3-yl)propan-2-yl)-2-(5-methylisoxazole-3-carboxamido)-N4-neopentylsuccinamide
   Show/Hide
C29H35ClN6O5
  1
1
IC50 = 690 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0916454
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxo-3-(pyridin-4-yl)propan-2-yl)-2-(5-methylisoxazole-3-carboxamido)-N4-neopentylsuccinamide
   Show/Hide
C29H35ClN6O5
  1
1
IC50 = 940 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0898590
 Compound Info 
(S)-2-acetamido-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentylsuccinamide
   Show/Hide
C28H38N4O4
  1
1
IC50 = 960 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0877532
 Compound Info 
(S)-N1-((S)-1-(2-chlorobenzylamino)-1-oxopropan-2-yl)-2-(5-methylisoxazole-3-carboxamido)-N4-neopentylsuccinamide
   Show/Hide
C24H32ClN5O5
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849442
 Compound Info 
N-((S)-3-(3-tert-Butyl-1,2,4-oxadiazol-5-yl)-1-((S)-1-(4-methylbenzylamino)-1-oxo-4-phenylbutan-2-ylamino)-1-oxopropan-2-yl)-5-methylisoxazole-3-carboxamide
   Show/Hide
C32H38N6O5
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT03087, Protein arginine N-methyltransferase 5
 Protein Info 
Protein ID: PT01116, RAF proto-oncogene serine/threonine-protein kinase
 Protein Info 
Protein ID: PT01221, TGF-beta receptor type-1
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0014985
 Compound Info 
BIBF-1120
   Show/Hide
 C31H33N5O4  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0017774
 Compound Info 
4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
   Show/Hide
 C25H15ClF2N4O2  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0117616
 Compound Info 
US10245267, Example 1
   Show/Hide
 C23H21F3N4O2  1
1
EC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0160473
 Compound Info 
2-(4-(2-(1H-pyrazol-3-ylamino)-1H-benzo[d]imidazol-1-yl)-6-methyl-1,3,5-triazin-2-ylamino)acetonitrile
   Show/Hide
 C16H14N10  1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CP0227790
 Compound Info 
4-(4-chlorophenyl)-6-(3-methoxypiperidin-1-yl)-N-[3-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]pyrimidin-2-amine
   Show/Hide
 C29H37ClN6O2  1
1
GI50 = 4400 nM
   TI
   LI
   LO
   TS
CP0472275
 Compound Info 
N-[3-[2-[3-amino-6-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyrazin-2-yl]benzimidazol-1-yl]phenyl]prop-2-enamide
   Show/Hide
 C29H29N9O  1
1
GI50 = 1700 nM
   TI
   LI
   LO
   TS
CP0544270
 Compound Info 
N-(3-tert-butylphenyl)-4-methyl-3-(6-morpholin-4-ylpyrimidin-4-yl)benzamide
   Show/Hide
 C26H30N4O2  1
1
EC50 = 6400 nM
   TI
   LI
   LO
   TS
CP0566040
 Compound Info 
US10245267, Example 390
   Show/Hide
 C23H22F3N5O3  1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0664754
 Compound Info 
(Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
   Show/Hide
 C28H28N4O4  1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Pleural effusion)
Cell Line Name Organism Disease
U-937
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
SU-DHL-1
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
SR
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
MC116
 Cell Line Info 
Homo sapiens (Human) B-cell non-Hodgkin lymphoma
K-562
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/A02
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/Adr
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/R7
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/DOX
 Cell Line Info 
Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
MDA-MB-231
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-415
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-468
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
SK-BR-3
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
AU565
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
CAL-51
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
CAL-120
 Cell Line Info 
Homo sapiens (Human) Breast carcinoma
DG-75
 Cell Line Info 
Homo sapiens (Human) Burkitt lymphoma
SUP-T1
 Cell Line Info 
Homo sapiens (Human) Childhood T lymphoblastic lymphoma
Pfeiffer
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
WSU-DLCL2
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
Karpas-422
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
DoHH2
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
KATO III
 Cell Line Info 
Homo sapiens (Human) Down syndrome
GIST-T1
 Cell Line Info 
Homo sapiens (Human) Gastrointestinal stromal tumor
GIST-5R
 Cell Line Info 
Homo sapiens (Human) Gastrointestinal stromal tumor
MZ-CRC-1
 Cell Line Info 
Homo sapiens (Human) Hereditary thyroid gland medullary carcinoma
L-428
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
KM-H2
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
T-47D
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/2a
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
T-47
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 MX100
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/VP
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-2a
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D:A18
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MVLN
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF/MX
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/Topo
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD2
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7aro
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M6
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-10
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M24
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7piGST
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-Y1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/ADM
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7:WS8
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-FLV1000
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-neo/Her2
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 cl.24
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/DX1
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-LC3
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D-KBluc
 Cell Line Info 
Homo sapiens (Human) Invasive breast carcinoma of no special type
Calu-3
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC78
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H3122
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H3255
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2122
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
COR-L105
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1437
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
HCC4006
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1792
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
DFCI032
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1355
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H460
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
U-1810
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
COR-L23/R
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
H460/MX20
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
H460R
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
H69AR
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
NCI-H69
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
GLC-4/ADR
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
STC 1
 Cell Line Info 
Homo sapiens (Human) Lung small cell carcinoma
RERF-LC-A1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
Calu-1
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
HCC95
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
RERF-LC-AI Tet-off
 Cell Line Info 
Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1650
 Cell Line Info 
Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H1666
 Cell Line Info 
Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H929
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-11
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
UTMC-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-12-PE
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
NCI-H226
 Cell Line Info 
Homo sapiens (Human) Pleural epithelioid mesothelioma
Karpas-1106P
 Cell Line Info 
Homo sapiens (Human) Primary mediastinal (thymic) large B-cell lymphoma