Brief Information of the Compound and Protein
Compound Name
[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
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PubChem ID
CID: 25183872
SID: 57291607
Canonical SMILES
CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O
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Compound Formula C14H19BCl2N2O4
Compound Structure
Protein Name
Proteasome subunit beta type-5
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28074
Gene Name
PSMB5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6 Homo sapiens (Human)  1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.884 nM
2 IC50 = 3.4 nM
3 IC50 = 7.73 nM