General Information of the Compound
Compound ID
CP0898590
Compound Name
(S)-2-acetamido-N1-((S)-1-(benzylamino)-1-oxo-4-phenylbutan-2-yl)-N4-neopentylsuccinamide
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Structure
Formula
C28H38N4O4
Molecular Weight
494.636
Canonical SMILES
CC(=O)N[C@@H](CC(=O)NCC(C)(C)C)C(=O)N[C@@H](CCc1ccccc1)C(=O)NCc1ccccc1
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InChI
InChI=1S/C28H38N4O4/c1-20(33)31-24(17-25(34)30-19-28(2,3)4)27(36)32-23(16-15-21-11-7-5-8-12-21)26(35)29-18-22-13-9-6-10-14-22/h5-14,23-24H,15-19H2,1-4H3,(H,29,35)(H,30,34)(H,31,33)(H,32,36)/t23-,24-/m0/s1
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InChIKey
JVOLOUHVFQIODG-ZEQRLZLVSA-N
Physicochemical Property
logP
2.4775
Rotatable Bonds
12
Heavy Atom Count
36
Polar Areas
116.4
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 90665954
ChEMBL ID
CHEMBL3218820
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02585, Proteasome subunit beta type-5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6 Homo sapiens (Human)  1
1
IC50 = 960 nM
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