Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000137
Cell Line Name	K562/A02
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0368
Tissue Information	Pleural effusion
Disease	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110) Chronic myeloid leukemia (ORDO: Orphanet_521)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT01546, ATP-dependent translocase ABCB1

Protein Info

Compound ID	Compound Name	Compound Formula
CP0543722 Compound Info	3-(4-chlorophenyl)-N-[4-(2-morpholin-4-ylethyl)phenyl]-4-oxophthalazine-1-carboxamide Show/Hide	C27H25ClN4O3	8
1	EC50 = 65.31 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2410 nM Bioactivity Info	TI LI LO TS
3	IC50 = 2460 nM Bioactivity Info	TI LI LO TS
4	IC50 = 3150 nM Bioactivity Info	TI LI LO TS
5	IC50 = 4310 nM Bioactivity Info	TI LI LO TS
6	IC50 = 6620 nM Bioactivity Info	TI LI LO TS
7	IC50 = 14270 nM Bioactivity Info	TI LI LO TS
8	IC50 = 83680 nM Bioactivity Info	TI LI LO TS
CP0389820 Compound Info	N-(4-tert-butylphenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide Show/Hide	C33H39N5O4	14
1	EC50 = 252.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1260 nM Bioactivity Info	TI LI LO TS
3	IC50 = 1270 nM Bioactivity Info	TI LI LO TS
4	IC50 = 3330 nM Bioactivity Info	TI LI LO TS
5	IC50 = 4330 nM Bioactivity Info	TI LI LO TS
6	IC50 = 6020 nM Bioactivity Info	TI LI LO TS
7	IC50 = 6320 nM Bioactivity Info	TI LI LO TS
8	IC50 = 10320 nM Bioactivity Info	TI LI LO TS
9	IC50 = 12520 nM Bioactivity Info	TI LI LO TS
10	IC50 = 17210 nM Bioactivity Info	TI LI LO TS
11	IC50 = 18390 nM Bioactivity Info	TI LI LO TS
12	IC50 = 34900 nM Bioactivity Info	TI LI LO TS
13	IC50 = 37180 nM Bioactivity Info	TI LI LO TS
14	IC50 = 37210 nM Bioactivity Info	TI LI LO TS
CP0444582 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(furan-2-yl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C29H31N5O4	10
1	EC50 = 1190 nM Bioactivity Info	TI LI LO TS
2	IC50 = 180 nM Bioactivity Info	TI LI LO TS
3	IC50 = 420 nM Bioactivity Info	TI LI LO TS
4	IC50 = 4880 nM Bioactivity Info	TI LI LO TS
5	IC50 = 16920 nM Bioactivity Info	TI LI LO TS
6	IC50 = 25680 nM Bioactivity Info	TI LI LO TS
7	IC50 = 38970 nM Bioactivity Info	TI LI LO TS
8	IC50 = 45320 nM Bioactivity Info	TI LI LO TS
9	IC50 = 76830 nM Bioactivity Info	TI LI LO TS
10	IC50 = 84320 nM Bioactivity Info	TI LI LO TS
CP0116921 Compound Info	1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolinyl)ethyl]phenyl}-4,5-dimethoxy-2-(3-quinolylcarboxamido)benzamide Show/Hide	C38H38N4O6	7
1	IC50 = 460 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1600 nM Bioactivity Info	TI LI LO TS
3	IC50 = 1970 nM Bioactivity Info	TI LI LO TS
4	IC50 = 3020 nM Bioactivity Info	TI LI LO TS
5	IC50 = 4970 nM Bioactivity Info	TI LI LO TS
6	IC50 = 8280 nM Bioactivity Info	TI LI LO TS
7	IC50 = 14390 nM Bioactivity Info	TI LI LO TS
CP0002778 Compound Info	4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide Show/Hide	C29H31N7O	1
1	IC50 = 580 nM Bioactivity Info	TI LI LO TS
CP0531428 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(2-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C31H33N5O4	1
1	IC50 = 920 nM Bioactivity Info	TI LI LO TS
CP0451088 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-thiophen-2-ylpyrimidin-2-yl)amino]benzamide Show/Hide	C29H31N5O3S	1
1	IC50 = 940 nM Bioactivity Info	TI LI LO TS
CP0547994 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzamide Show/Hide	C37H37N5O3	1
1	IC50 = 1030 nM Bioactivity Info	TI LI LO TS
CP0419245 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[[4-(3-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C37H37N5O4	1
1	IC50 = 1050 nM Bioactivity Info	TI LI LO TS
CP0553197 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[[4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide Show/Hide	C32H35N5O3	1
1	IC50 = 1180 nM Bioactivity Info	TI LI LO TS
CP0534059 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-pyridin-2-ylpyrimidin-2-yl)amino]benzamide Show/Hide	C36H36N6O3	1
1	IC50 = 1220 nM Bioactivity Info	TI LI LO TS
CP0532221 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(4-methoxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C32H35N5O4	1
1	IC50 = 1770 nM Bioactivity Info	TI LI LO TS
CP0547996 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[[4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide Show/Hide	C38H39N5O3	1
1	IC50 = 1950 nM Bioactivity Info	TI LI LO TS
CP0547993 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[[4-(2-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C37H37N5O4	1
1	IC50 = 1980 nM Bioactivity Info	TI LI LO TS
CP0444569 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-thiophen-2-ylpyrimidin-2-yl)amino]benzamide Show/Hide	C35H35N5O3S	1
1	IC50 = 2310 nM Bioactivity Info	TI LI LO TS
CP0532223 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzamide Show/Hide	C31H33N5O3	1
1	IC50 = 2470 nM Bioactivity Info	TI LI LO TS
CP0532225 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-hydroxy-4-oxochromene-2-carboxamide Show/Hide	C29H28N2O6	1
1	IC50 = 2750 nM Bioactivity Info	TI LI LO TS
CP0531430 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C31H32FN5O3	1
1	IC50 = 2950 nM Bioactivity Info	TI LI LO TS
CP0531429 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(3-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C31H33N5O4	1
1	IC50 = 3010 nM Bioactivity Info	TI LI LO TS
CP0552099 Compound Info	3-(4-chlorophenyl)-N-[(4-cyanophenyl)methyl]-4-oxophthalazine-1-carboxamide Show/Hide	C23H15ClN4O2	1
1	IC50 = 3120 nM Bioactivity Info	TI LI LO TS
CP0541483 Compound Info	4-tert-butyl-N-[2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]phenyl]benzamide Show/Hide	C33H39N5O4	1
1	IC50 = 3420 nM Bioactivity Info	TI LI LO TS
CP0532227 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzamide Show/Hide	C37H36FN5O3	1
1	IC50 = 4020 nM Bioactivity Info	TI LI LO TS
CP0541484 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-[4-(trifluoromethoxy)phenyl]benzamide Show/Hide	C30H30F3N5O5	1
1	IC50 = 4520 nM Bioactivity Info	TI LI LO TS
CP0543748 Compound Info	N-benzhydryl-3-(4-chlorophenyl)-4-oxophthalazine-1-carboxamide Show/Hide	C28H20ClN3O2	1
1	IC50 = 5180 nM Bioactivity Info	TI LI LO TS
CP0478387 Compound Info	N-(4-butylphenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide Show/Hide	C33H39N5O4	1
1	IC50 = 6250 nM Bioactivity Info	TI LI LO TS
CP0543747 Compound Info	3-(4-chlorophenyl)-4-oxo-N-[[3-(trifluoromethoxy)phenyl]methyl]phthalazine-1-carboxamide Show/Hide	C23H15ClF3N3O3	1
1	IC50 = 6350 nM Bioactivity Info	TI LI LO TS
CP0036382 Compound Info	CAS_52-53-9 Show/Hide	C27H38N2O4	5
1	IC50 = 6470 nM Bioactivity Info	TI LI LO TS
2	IC50 = 10730 nM Bioactivity Info	TI LI LO TS
3	IC50 = 17250 nM Bioactivity Info	TI LI LO TS
4	IC50 = 17550 nM Bioactivity Info	TI LI LO TS
5	IC50 = 31280 nM Bioactivity Info	TI LI LO TS
CP0451089 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-6-fluoro-4-oxochromene-2-carboxamide Show/Hide	C29H27FN2O5	1
1	IC50 = 6620 nM Bioactivity Info	TI LI LO TS
CP0532222 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-pyridin-2-ylpyrimidin-2-yl)amino]benzamide Show/Hide	C30H32N6O3	1
1	IC50 = 6900 nM Bioactivity Info	TI LI LO TS
CP0465652 Compound Info	N-(4-chlorophenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide Show/Hide	C29H30ClN5O4	1
1	IC50 = 6930 nM Bioactivity Info	TI LI LO TS
CP0576510 Compound Info	3-(4-chlorophenyl)-N-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-oxophthalazine-1-carboxamide Show/Hide	C32H27ClN4O2	1
1	IC50 = 6930 nM Bioactivity Info	TI LI LO TS
CP0410563 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-methylphenyl)benzamide Show/Hide	C30H33N5O4	1
1	IC50 = 7650 nM Bioactivity Info	TI LI LO TS
CP0410565 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3,4-dimethoxyphenyl)benzamide Show/Hide	C31H35N5O6	1
1	IC50 = 7820 nM Bioactivity Info	TI LI LO TS
CP0465651 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-fluorophenyl)benzamide Show/Hide	C29H30FN5O4	1
1	IC50 = 8290 nM Bioactivity Info	TI LI LO TS
CP0478388 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-methoxyphenyl)benzamide Show/Hide	C30H33N5O5	1
1	IC50 = 8380 nM Bioactivity Info	TI LI LO TS
CP0451522 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3-methoxyphenyl)benzamide Show/Hide	C30H33N5O5	1
1	IC50 = 8730 nM Bioactivity Info	TI LI LO TS
CP0576506 Compound Info	N-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-4-oxophthalazine-1-carboxamide Show/Hide	C22H14ClN5O2	1
1	IC50 = 9350 nM Bioactivity Info	TI LI LO TS
CP0532224 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-oxochromene-2-carboxamide Show/Hide	C29H28N2O5	1
1	IC50 = 9610 nM Bioactivity Info	TI LI LO TS
CP0576508 Compound Info	3-(4-chlorophenyl)-4-oxo-N-[(3,4,5-trimethoxyphenyl)methyl]phthalazine-1-carboxamide Show/Hide	C25H22ClN3O5	1
1	IC50 = 10410 nM Bioactivity Info	TI LI LO TS
CP0465650 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3-methylphenyl)benzamide Show/Hide	C30H33N5O4	1
1	IC50 = 12160 nM Bioactivity Info	TI LI LO TS
CP0576505 Compound Info	3-(4-chlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxophthalazine-1-carboxamide Show/Hide	C26H24ClN5O2	1
1	IC50 = 12280 nM Bioactivity Info	TI LI LO TS
CP0543746 Compound Info	3-(4-chlorophenyl)-N-(2-morpholin-4-ylethyl)-4-oxophthalazine-1-carboxamide Show/Hide	C21H21ClN4O3	1
1	IC50 = 13620 nM Bioactivity Info	TI LI LO TS
CP0571178 Compound Info	3-(4-chlorophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxophthalazine-1-carboxamide Show/Hide	C25H22ClN3O4	1
1	IC50 = 13790 nM Bioactivity Info	TI LI LO TS
CP0576759 Compound Info	3-(4-chlorophenyl)-N-(4-morpholin-4-ylphenyl)-4-oxophthalazine-1-carboxamide Show/Hide	C25H21ClN4O3	1
1	IC50 = 14460 nM Bioactivity Info	TI LI LO TS
CP0036082 Compound Info	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine Show/Hide	C22H24ClFN4O3	1
1	IC50 = 19970 nM Bioactivity Info	TI LI LO TS
CP0578337 Compound Info	N,N-dibenzyl-3-(4-chlorophenyl)-4-oxophthalazine-1-carboxamide Show/Hide	C29H22ClN3O2	1
1	IC50 = 20610 nM Bioactivity Info	TI LI LO TS
CP0390060 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-nitrophenyl)benzamide Show/Hide	C29H30N6O6	1
1	IC50 = 21070 nM Bioactivity Info	TI LI LO TS
CP0410562 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(2-methylphenyl)benzamide Show/Hide	C30H33N5O4	1
1	IC50 = 21910 nM Bioactivity Info	TI LI LO TS
CP0572938 Compound Info	3-(4-chlorophenyl)-4-oxo-N-(2-phenylethyl)phthalazine-1-carboxamide Show/Hide	C23H18ClN3O2	1
1	IC50 = 22730 nM Bioactivity Info	TI LI LO TS
CP0495662 Compound Info	N-(3-chlorophenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide Show/Hide	C29H30ClN5O4	1
1	IC50 = 22820 nM Bioactivity Info	TI LI LO TS
CP0576760 Compound Info	3-(4-chlorophenyl)-N-[(4-methoxyphenyl)methyl]-4-oxophthalazine-1-carboxamide Show/Hide	C23H18ClN3O3	1
1	IC50 = 24280 nM Bioactivity Info	TI LI LO TS
CP0410564 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-phenylbenzamide Show/Hide	C29H31N5O4	1
1	IC50 = 25520 nM Bioactivity Info	TI LI LO TS
CP0523551 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(2-nitrophenyl)benzamide Show/Hide	C29H30N6O6	1
1	IC50 = 26920 nM Bioactivity Info	TI LI LO TS
CP0410560 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3-nitrophenyl)benzamide Show/Hide	C29H30N6O6	1
1	IC50 = 27690 nM Bioactivity Info	TI LI LO TS
CP0475330 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3,4,5-trimethoxyphenyl)benzamide Show/Hide	C32H37N5O7	1
1	IC50 = 31920 nM Bioactivity Info	TI LI LO TS
CP0576509 Compound Info	3-(4-chlorophenyl)-4-oxo-N-(pyridin-4-ylmethyl)phthalazine-1-carboxamide Show/Hide	C21H15ClN4O2	1
1	IC50 = 34750 nM Bioactivity Info	TI LI LO TS
CP0569303 Compound Info	3-(4-chlorophenyl)-4-oxo-N-[(4-phenylphenyl)methyl]phthalazine-1-carboxamide Show/Hide	C28H20ClN3O2	1
1	IC50 = 35120 nM Bioactivity Info	TI LI LO TS
CP0568028 Compound Info	3-(4-chlorophenyl)-N-[2-(3-fluorophenyl)ethyl]-4-oxophthalazine-1-carboxamide Show/Hide	C23H17ClFN3O2	1
1	IC50 = 46320 nM Bioactivity Info	TI LI LO TS
CP0576507 Compound Info	3-(4-chlorophenyl)-N-[2-(3-chlorophenyl)ethyl]-4-oxophthalazine-1-carboxamide Show/Hide	C23H17Cl2N3O2	1
1	IC50 = 46540 nM Bioactivity Info	TI LI LO TS
CP0574618 Compound Info	3-(4-chlorophenyl)-4-oxo-N-(pyridin-3-ylmethyl)phthalazine-1-carboxamide Show/Hide	C21H15ClN4O2	1
1	IC50 = 50900 nM Bioactivity Info	TI LI LO TS
CP0543855 Compound Info	3-(4-chlorophenyl)-N-(3-morpholin-4-ylpropyl)-4-oxophthalazine-1-carboxamide Show/Hide	C22H23ClN4O3	1
1	IC50 = 65560 nM Bioactivity Info	TI LI LO TS
CP0444570 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-7-methyl-4-oxochromene-2-carboxamide Show/Hide	C30H30N2O5	1
1	IC50 = 84850 nM Bioactivity Info	TI LI LO TS
CP0141589 Compound Info	3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester Show/Hide	C26H35N3O5	1
1	IC50 = 86790 nM Bioactivity Info	TI LI LO TS
CP0664710 Compound Info	SID49681823 Show/Hide	C27H30ClNO11	1
1	IC50 = 96910 nM Bioactivity Info	TI LI LO TS

Cell Viability or Cytotoxicity Assay

Compound ID	Compound Name	Compound Formula
CP0036382 Compound Info	CAS_52-53-9 Show/Hide	C27H38N2O4	1
1	IC50 = 56240 nM	TI LI LO TS
CP0390060 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-nitrophenyl)benzamide Show/Hide	C29H30N6O6	1
1	IC50 > 100000 nM	TI LI LO TS
CP0410562 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(2-methylphenyl)benzamide Show/Hide	C30H33N5O4	1
1	IC50 > 100000 nM	TI LI LO TS
CP0410563 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-methylphenyl)benzamide Show/Hide	C30H33N5O4	1
1	IC50 > 100000 nM	TI LI LO TS
CP0444569 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-thiophen-2-ylpyrimidin-2-yl)amino]benzamide Show/Hide	C35H35N5O3S	1
1	IC50 > 100000 nM	TI LI LO TS
CP0475330 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3,4,5-trimethoxyphenyl)benzamide Show/Hide	C32H37N5O7	1
1	IC50 > 100000 nM	TI LI LO TS
CP0523551 Compound Info	2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(2-nitrophenyl)benzamide Show/Hide	C29H30N6O6	1
1	IC50 > 100000 nM	TI LI LO TS
CP0532222 Compound Info	N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-pyridin-2-ylpyrimidin-2-yl)amino]benzamide Show/Hide	C30H32N6O3	1
1	IC50 = 89620 nM	TI LI LO TS
CP0541483 Compound Info	4-tert-butyl-N-[2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]phenyl]benzamide Show/Hide	C33H39N5O4	1
1	IC50 > 100000 nM	TI LI LO TS
CP0545962 Compound Info	N-(4-morpholin-4-ylphenyl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide Show/Hide	C22H23N5O2	1
1	IC50 > 100000 nM	TI LI LO TS
CP0547996 Compound Info	N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[[4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide Show/Hide	C38H39N5O3	1
1	IC50 = 9533000 nM	TI LI LO TS
CP0664710 Compound Info	SID49681823 Show/Hide	C27H30ClNO11	1
1	IC50 = 96910 nM	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Pleural effusion)

Cell Line Name		Organism	Disease
U-937	Cell Line Info	Homo sapiens (Human)	Adult acute monocytic leukemia
SU-DHL-1	Cell Line Info	Homo sapiens (Human)	Anaplastic large cell lymphoma, ALK-positive
SR	Cell Line Info	Homo sapiens (Human)	Anaplastic large cell lymphoma, ALK-positive
MC116	Cell Line Info	Homo sapiens (Human)	B-cell non-Hodgkin lymphoma
K-562	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/Adr	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/R7	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/DOX	Cell Line Info	Homo sapiens (Human)	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
MDA-MB-231	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
MDA-MB-415	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
MDA-MB-468	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
SK-BR-3	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
AU565	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
CAL-51	Cell Line Info	Homo sapiens (Human)	Breast carcinoma
CAL-120	Cell Line Info	Homo sapiens (Human)	Breast carcinoma
DG-75	Cell Line Info	Homo sapiens (Human)	Burkitt lymphoma
SUP-T1	Cell Line Info	Homo sapiens (Human)	Childhood T lymphoblastic lymphoma
Pfeiffer	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
WSU-DLCL2	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
Karpas-422	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
DoHH2	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma germinal center B-cell type
KATO III	Cell Line Info	Homo sapiens (Human)	Down syndrome
GIST-T1	Cell Line Info	Homo sapiens (Human)	Gastrointestinal stromal tumor
GIST-5R	Cell Line Info	Homo sapiens (Human)	Gastrointestinal stromal tumor
MZ-CRC-1	Cell Line Info	Homo sapiens (Human)	Hereditary thyroid gland medullary carcinoma
L-428	Cell Line Info	Homo sapiens (Human)	Hodgkin lymphoma
KM-H2	Cell Line Info	Homo sapiens (Human)	Hodgkin lymphoma
T-47D	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/2a	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
T-47	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7 MX100	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/VP	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7-2a	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
T47D:A18	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MVLN	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF/MX	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/Topo	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/NOD2	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7aro	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/MRP1-M6	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/MRP1-10	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/MRP1-M24	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/NOD1	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7piGST	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7-Y1	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7/ADM	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7:WS8	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7-FLV1000	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7-neo/Her2	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7 cl.24	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF-7/DX1	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
MCF7-LC3	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
T47D-KBluc	Cell Line Info	Homo sapiens (Human)	Invasive breast carcinoma of no special type
Calu-6	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
Calu-3	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
HCC78	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H3122	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H3255	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H2122	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
COR-L105	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H1437	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
HCC4006	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H1792	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
DFCI032	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H1355	Cell Line Info	Homo sapiens (Human)	Lung adenocarcinoma
NCI-H460	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
U-1810	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
COR-L23/R	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
H460/MX20	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
H460R	Cell Line Info	Homo sapiens (Human)	Lung large cell carcinoma
H69AR	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
NCI-H69	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
GLC-4/ADR	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
STC 1	Cell Line Info	Homo sapiens (Human)	Lung small cell carcinoma
RERF-LC-A1	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
Calu-1	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
HCC95	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
RERF-LC-AI Tet-off	Cell Line Info	Homo sapiens (Human)	Lung squamous cell carcinoma
NCI-H1650	Cell Line Info	Homo sapiens (Human)	Minimally invasive lung adenocarcinoma
NCI-H1666	Cell Line Info	Homo sapiens (Human)	Minimally invasive lung adenocarcinoma
NCI-H929	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
KMS-11	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
UTMC-2	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
KMS-12-PE	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
NCI-H226	Cell Line Info	Homo sapiens (Human)	Pleural epithelioid mesothelioma
Karpas-1106P	Cell Line Info	Homo sapiens (Human)	Primary mediastinal (thymic) large B-cell lymphoma

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han