Brief Information of the Compound and Protein
Compound Name
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
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PubChem ID
CID: 123631
SID: 14833109
Canonical SMILES
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1
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Compound Formula C22H24ClFN4O3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000137 K562/A02 Homo sapiens (Human)  1
1
IC50 = 19970 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 1000 nM