Brief Information of the Compound and Protein
Compound Name
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(4-methoxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
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Canonical SMILES
COc1ccc(cc1)-c1ccnc(Nc2cc(ccc2C)C(=O)NCCN2CCc3cc(OC)c(OC)cc3C2)n1
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Compound Formula C32H35N5O4
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000137 K562/A02 Homo sapiens (Human)  1
1
IC50 = 1770 nM
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