Brief Information of the Compound and Protein
Compound Name
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-pyridin-2-ylpyrimidin-2-yl)amino]benzamide
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Canonical SMILES
COc1cc2CCN(CCNC(=O)c3ccc(C)c(Nc4nccc(n4)-c4ccccn4)c3)Cc2cc1OC
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Compound Formula C30H32N6O3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000137 K562/A02 Homo sapiens (Human)  1
1
IC50 = 6900 nM
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