Brief Information of the Compound and Protein
Compound Name
3-(4-chlorophenyl)-N-[4-(2-morpholin-4-ylethyl)phenyl]-4-oxophthalazine-1-carboxamide
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PubChem ID
CID: 163322235
Canonical SMILES
Clc1ccc(cc1)-n1nc(C(=O)Nc2ccc(CCN3CCOCC3)cc2)c2ccccc2c1=O
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Compound Formula C27H25ClN4O3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000137 K562/A02 Homo sapiens (Human)  8
1
EC50 = 65.31 nM
   TI
   LI
   LO
   TS
2
IC50 = 2410 nM
   TI
   LI
   LO
   TS
3
IC50 = 2460 nM
   TI
   LI
   LO
   TS
4
IC50 = 3150 nM
   TI
   LI
   LO
   TS
5
IC50 = 4310 nM
   TI
   LI
   LO
   TS
6
IC50 = 6620 nM
   TI
   LI
   LO
   TS
7
IC50 = 14270 nM
   TI
   LI
   LO
   TS
8
IC50 = 83680 nM
   TI
   LI
   LO
   TS