General Information of the Cell Line
Cell Line ID
CL000241
Cell Line Name
DG-75
Synonyms
D.G.-75
DG 75
DG75
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0244
Tissue Information
Pleural effusion
Disease
Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00871, Sodium-dependent serotonin transporter
Compound ID Compound Name Compound Formula
CP0400303
1-(4-Methylsulfanyl-phenyl)-propylamine
   Show/Hide
C10H15NS
 1
1
EC50 = 4786.3 nM
   TI
   LI
   LO
   TS
CP0876359
2-(4-tert-Butylsulfanyl-phenyl)-1-methyl-ethylamine
   Show/Hide
C13H21NS
 1
1
EC50 = 7762.47 nM
   TI
   LI
   LO
   TS
CP0494726
2-(N-Methyl-N-hydroxy)amino-1-(4-ethylthiophenyl)propane
   Show/Hide
C12H19NOS
 1
1
EC50 = 18620.87 nM
   TI
   LI
   LO
   TS
CP0010255
(RS)-3,4-(methylenedioxy)methamphetamine
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C11H15NO2
 1
1
EC50 = 32359.37 nM
   TI
   LI
   LO
   TS
CP0498599
(+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine
   Show/Hide
C10H15NO
 1
1
EC50 = 32359.37 nM
   TI
   LI
   LO
   TS
CP0384030
2-N-(2-Methoxyethyl)amino-1-(4-methylthiophenyl)propane
   Show/Hide
C13H21NOS
 1
1
EC50 = 33113.11 nM
   TI
   LI
   LO
   TS
CP0384029
2-N-Propargylamino-1-(4-methylthiophenyl)propane
   Show/Hide
C13H17NS
 1
1
EC50 = 38018.94 nM
   TI
   LI
   LO
   TS
CP0453029
2-N-Methylamino-1-(4-methylthiophenyl)butane
   Show/Hide
C12H19NS
 1
1
EC50 = 46773.51 nM
   TI
   LI
   LO
   TS
CP0452313
2-N-Cyclopropylamino-1-(4-methylthiophenyl)butane
   Show/Hide
C14H21NS
 1
1
EC50 = 60255.96 nM
   TI
   LI
   LO
   TS
CP0377023
2-Amino-1-(4-ethylthiophenyl)butane
   Show/Hide
C12H19NS
 1
1
EC50 = 69183.1 nM
   TI
   LI
   LO
   TS
CP0452317
2-N-Hydroxyamino-1-(4-ethylthiophenyl)butane
   Show/Hide
C12H19NOS
 1
1
EC50 = 77624.71 nM
   TI
   LI
   LO
   TS
CP0453023
2-N-Hydroxyamino-1-(4-methylthiophenyl)butane
   Show/Hide
C11H17NOS
 1
1
EC50 = 77624.71 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0395888
1,3-bis(4-(methylthio)phenyl)propan-2-amine
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C17H21NS2  1
1
EC50 = 25118.86 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Pleural effusion)
Cell Line Name Organism Disease
U-937 Homo sapiens (Human) Adult acute monocytic leukemia
SU-DHL-1 Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
SR Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
MC116 Homo sapiens (Human) B-cell non-Hodgkin lymphoma
K-562 Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/A02 Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/Adr Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/R7 Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
K562/DOX Homo sapiens (Human) Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
MDA-MB-231 Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-415 Homo sapiens (Human) Breast adenocarcinoma
MDA-MB-468 Homo sapiens (Human) Breast adenocarcinoma
SK-BR-3 Homo sapiens (Human) Breast adenocarcinoma
AU565 Homo sapiens (Human) Breast adenocarcinoma
CAL-51 Homo sapiens (Human) Breast carcinoma
CAL-120 Homo sapiens (Human) Breast carcinoma
SUP-T1 Homo sapiens (Human) Childhood T lymphoblastic lymphoma
Pfeiffer Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
WSU-DLCL2 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
Karpas-422 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
DoHH2 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
KATO III Homo sapiens (Human) Down syndrome
GIST-T1 Homo sapiens (Human) Gastrointestinal stromal tumor
GIST-5R Homo sapiens (Human) Gastrointestinal stromal tumor
MZ-CRC-1 Homo sapiens (Human) Hereditary thyroid gland medullary carcinoma
L-428 Homo sapiens (Human) Hodgkin lymphoma
KM-H2 Homo sapiens (Human) Hodgkin lymphoma
T-47D Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/2a Homo sapiens (Human) Invasive breast carcinoma of no special type
T-47 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 MX100 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/VP Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-2a Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D:A18 Homo sapiens (Human) Invasive breast carcinoma of no special type
MVLN Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF/MX Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/Topo Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD2 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7aro Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M6 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-10 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/MRP1-M24 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/NOD1 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7piGST Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-Y1 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7/ADM Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7:WS8 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7-FLV1000 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-neo/Her2 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7 cl.24 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF-7/DX1 Homo sapiens (Human) Invasive breast carcinoma of no special type
MCF7-LC3 Homo sapiens (Human) Invasive breast carcinoma of no special type
T47D-KBluc Homo sapiens (Human) Invasive breast carcinoma of no special type
Calu-6 Homo sapiens (Human) Lung adenocarcinoma
Calu-3 Homo sapiens (Human) Lung adenocarcinoma
HCC78 Homo sapiens (Human) Lung adenocarcinoma
NCI-H3122 Homo sapiens (Human) Lung adenocarcinoma
NCI-H3255 Homo sapiens (Human) Lung adenocarcinoma
NCI-H2122 Homo sapiens (Human) Lung adenocarcinoma
COR-L105 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1437 Homo sapiens (Human) Lung adenocarcinoma
HCC4006 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1792 Homo sapiens (Human) Lung adenocarcinoma
DFCI032 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1355 Homo sapiens (Human) Lung adenocarcinoma
NCI-H460 Homo sapiens (Human) Lung large cell carcinoma
U-1810 Homo sapiens (Human) Lung large cell carcinoma
COR-L23/R Homo sapiens (Human) Lung large cell carcinoma
H460/MX20 Homo sapiens (Human) Lung large cell carcinoma
H460R Homo sapiens (Human) Lung large cell carcinoma
H69AR Homo sapiens (Human) Lung small cell carcinoma
NCI-H69 Homo sapiens (Human) Lung small cell carcinoma
GLC-4/ADR Homo sapiens (Human) Lung small cell carcinoma
STC 1 Homo sapiens (Human) Lung small cell carcinoma
RERF-LC-A1 Homo sapiens (Human) Lung squamous cell carcinoma
Calu-1 Homo sapiens (Human) Lung squamous cell carcinoma
HCC95 Homo sapiens (Human) Lung squamous cell carcinoma
RERF-LC-AI Tet-off Homo sapiens (Human) Lung squamous cell carcinoma
NCI-H1650 Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H1666 Homo sapiens (Human) Minimally invasive lung adenocarcinoma
NCI-H929 Homo sapiens (Human) Plasma cell myeloma
KMS-11 Homo sapiens (Human) Plasma cell myeloma
UTMC-2 Homo sapiens (Human) Plasma cell myeloma
KMS-12-PE Homo sapiens (Human) Plasma cell myeloma
NCI-H226 Homo sapiens (Human) Pleural epithelioid mesothelioma
Karpas-1106P Homo sapiens (Human) Primary mediastinal (thymic) large B-cell lymphoma