General Information of the Compound
| Compound ID |
CP0498599
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| Compound Name |
(+/-)2-(4-Methoxy-phenyl)-1-methyl-ethylamine
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| Synonyms |
Para-Methoxyamphetamine
(+-)-p-Methoxy-alpha-methylphenethylamine
(+-)-p-Methoxyamphetamine
1-(4-Methoxybenzyl)ethylamine
1-(4-methoxyphenyl)propan-2-amine
1-p-Methoxyphenyl-2-aminopropane
1-p-Methoxyphenyl-2-propylamine
2-Amino-1-(4'-methoxyphenyl)propane
23239-32-9
4-Methoxyamphetamine
50505-80-1
64-13-1
Beta-methoxyamphetamine
DEA No 7411
DL-p-Methoxy-alpha-methylphenethylamine
NSC 32757
beta-methoxyamphetamine
p-Methoxy-alpha-methylphenethylamine
p-Methoxyamphetamine
para-methoxyamphetamine
paramethoxyamphetamine
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| Structure |
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| Formula |
C10H15NO
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| Molecular Weight |
165.236
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| Canonical SMILES |
COc1ccc(CC(C)N)cc1
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| InChI |
InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3
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| InChIKey |
NEGYEDYHPHMHGK-UHFFFAOYSA-N
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| CAS |
23239-32-9
64-13-1
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00871, Sodium-dependent serotonin transporter
Protein ID: PT00891, Sodium-dependent serotonin transporter
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000004 | SH-SY5Y | Homo sapiens (Human) | 1 |
| 1 |
EC50 > 10000000 nM
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TI
LI
LO
TS
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| CL000006 | HEK293 | Homo sapiens (Human) | 1 |
| 1 |
EC50 = 457088.19 nM
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TI
LI
LO
TS
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Clinical Information about the Compound
Drug 1 ( Beta-methoxyamphetamine )
| Drug Name | Beta-methoxyamphetamine | ||
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| Target(s) |
Monoamine oxidase type A (MAO-A)
Inhibitor
Serotonin transporter (SERT)
Inhibitor
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