Brief Information of the Compound and Protein
Compound Name
[3-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenoxy]-6-hydroxy-1-benzothiophen-2-yl]-(4-fluoro-2-methylphenyl)methanone
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PubChem ID
CID: 137503342
Canonical SMILES
Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CC(CF)C2)cc1
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Compound Formula C28H25F2NO4S
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000916 MCF7:WS8 Homo sapiens (Human)  2
1
IC50 = 2.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.631 nM
   TI
   LI
   LO
   TS