Protein Information

General Information of the Protein

Protein ID	PT06104
Protein Name	Solute carrier family 40 member 1
Secondarily Protein Name	Ferroportin-1 Iron-regulated transporter 1
Gene Name	SLC40A1
Secondarily Gene Name	FPN FPN1 IREG1 SLC11A3 MSTP079
Sequence	MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKLFACGPDAKEVRKENQANTSVV Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Transporter > Electrochemical transporter > SLC superfamily of solute carriers > SLC40 iron transporter
Function	Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (PubMed:15692071, PubMed:24304836, PubMed:22178646, PubMed:29599243, PubMed:30247984, PubMed:22682227, PubMed:29237594). Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity). When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (PubMed:22682227, PubMed:29237594, PubMed:32814342). Show/Hide
Uniprot ID	Primary ID: Q9NP59 Secondarily ID: Q6FI62 Q7Z4F8 Q8IVB2 Q9NRL0 Show/Hide
Ensembl ID	ENSG00000138449
HGNC ID	HGNC:10909
Subcellular Location	Cell membrane Basolateral cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000006 , HEK293

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0444988 Compound Info	N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-2-[[(2R)-3-[(Z)-1,2-bis(diethoxyphosphoryl)ethenyl]sulfanyl-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide Show/Hide	C95H151N21O21P2S	1
1	EC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0480668 Compound Info	N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-sulfanylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide Show/Hide	C85H131N21O15S	1
1	EC50 = 4.2 nM Bioactivity Info	TI LI LO TS
CP0563562 Compound Info	2-[[2-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[2-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-4-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-4-oxo-1-phenylbutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]acetic acid Show/Hide	C86H133N21O15S	1
1	EC50 = 4.2 nM Bioactivity Info	TI LI LO TS
CP0887768 Compound Info	2-(2-{bis[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide tetrahydrochloride Show/Hide	C30H33Cl4FN8O2	2
1	EC50 = 6 nM Bioactivity Info	TI LI LO TS
2	EC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0429395 Compound Info	ditert-butyl (Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enedioate Show/Hide	C97H149N21O19S	1
1	EC50 = 6.3 nM Bioactivity Info	TI LI LO TS
CP0504907 Compound Info	(Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enediamide Show/Hide	C89H135N23O17S	1
1	EC50 = 8.4 nM Bioactivity Info	TI LI LO TS
CP0480666 Compound Info	N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-2-[[(2R)-3-[(E)-1,2-bis(tert-butylsulfonyl)ethenyl]sulfanyl-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide Show/Hide	C95H149N21O19S3	1
1	EC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0448320 Compound Info	diethyl (Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enedioate Show/Hide	C93H141N21O19S	1
1	EC50 = 10.4 nM Bioactivity Info	TI LI LO TS
CP0397750 Compound Info	dimethyl (Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enedioate Show/Hide	C91H137N21O19S	1
1	EC50 = 12.6 nM Bioactivity Info	TI LI LO TS
CP0399572 Compound Info	N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2R)-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-[(Z)-1-phenyl-2-sulfamoylethenyl]sulfanylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide Show/Hide	C93H138N22O17S2	1
1	EC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0874584 Compound Info	1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-chloropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide Show/Hide	C21H22ClN7O	2
1	EC50 = 43 nM Bioactivity Info	TI LI LO TS
2	EC50 = 470 nM Bioactivity Info	TI LI LO TS
CP0456167 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-N-[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C86H128N18O12S3	1
1	EC50 = 44.2 nM Bioactivity Info	TI LI LO TS
CP0460308 Compound Info	(5R,8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-20-(3,3-diphenylpropanoylamino)-N-[2-[2-[2-(hexadecanoylamino)ethoxy]ethoxy]ethyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide Show/Hide	C75H112N14O10S3	1
1	EC50 = 52.3 nM Bioactivity Info	TI LI LO TS
CP0415576 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C60H79N15O9S3	1
1	EC50 = 54.3 nM Bioactivity Info	TI LI LO TS
CP0880270 Compound Info	1-(2-((2-(1H-benzo[d]imidazol-2-yl)ethyl)amino)ethyl)-N-((3-fluoropyridin-2-yl)methyl)-1H-1,2,3-triazole-4-carboxamide Show/Hide	C20H21FN8O	2
1	EC50 = 69 nM Bioactivity Info	TI LI LO TS
2	EC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0874581 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-chloropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H21ClN6O2	2
1	EC50 = 71 nM Bioactivity Info	TI LI LO TS
2	EC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0874591 Compound Info	2-(2-{bis[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C30H29FN8OS	2
1	EC50 = 71 nM Bioactivity Info	TI LI LO TS
2	EC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0903130 Compound Info	1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide tetrahydrochloride Show/Hide	C21H26Cl4FN7O	2
1	EC50 = 75 nM Bioactivity Info	TI LI LO TS
2	EC50 = 620 nM Bioactivity Info	TI LI LO TS
CP0456168 Compound Info	2-[[2-[[(2S,3R)-1-[[(5R,8S,14S,17S,20R,23S,26S,29R)-8-benzhydryl-26-benzyl-29-carbamoyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-trien-5-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]acetic acid Show/Hide	C66H89N17O13S3	1
1	EC50 = 75.1 nM Bioactivity Info	TI LI LO TS
CP0903120 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide trihydrochloride Show/Hide	C21H24Cl3FN6O2	2
1	EC50 = 81 nM Bioactivity Info	TI LI LO TS
2	EC50 = 420 nM Bioactivity Info	TI LI LO TS
CP0445523 Compound Info	(8S,14S,17S,20R,23S,26S,29R)-N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C64H89N15O10S3	1
1	EC50 = 92.3 nM Bioactivity Info	TI LI LO TS
CP0415575 Compound Info	(5R,8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-20-(3,3-diphenylpropanoylamino)-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide Show/Hide	C53H69N13O7S3	1
1	EC50 = 103.8 nM Bioactivity Info	TI LI LO TS
CP0450586 Compound Info	(5R,8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-20-(3,3,3-triphenylpropanoylamino)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide Show/Hide	C59H73N13O7S3	1
1	EC50 = 112.7 nM Bioactivity Info	TI LI LO TS
CP0942114 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H23Cl4FN6OS	2
1	EC50 = 130 nM Bioactivity Info	TI LI LO TS
2	EC50 = 740 nM Bioactivity Info	TI LI LO TS
CP0901637 Compound Info	2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C22H21FN6O2	2
1	EC50 = 150 nM Bioactivity Info	TI LI LO TS
2	EC50 = 500 nM Bioactivity Info	TI LI LO TS
CP0415621 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C66H92N16O11S3	1
1	EC50 = 164.5 nM Bioactivity Info	TI LI LO TS
CP0887764 Compound Info	1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1H-pyrazole-4-carboxamide trihydrochloride Show/Hide	C23H28Cl3N7O	2
1	EC50 = 194 nM Bioactivity Info	TI LI LO TS
2	EC50 = 750 nM Bioactivity Info	TI LI LO TS
CP0480667 Compound Info	(Z)-3-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylprop-2-enoic acid Show/Hide	C88H133N21O17S	1
1	EC50 = 218.1 nM Bioactivity Info	TI LI LO TS
CP0901639 Compound Info	2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H21FN6OS	2
1	EC50 = 220 nM Bioactivity Info	TI LI LO TS
2	EC50 = 530 nM Bioactivity Info	TI LI LO TS
CP0903140 Compound Info	2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide Show/Hide	C21H21FN6O2	2
1	EC50 = 220 nM Bioactivity Info	TI LI LO TS
2	EC50 = 930 nM Bioactivity Info	TI LI LO TS
CP0513226 Compound Info	N-[(8S,11S,14R,17S,20S)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-trien-20-yl]-3,3-diphenylpropanamide Show/Hide	C52H68N12O6S3	1
1	EC50 = 268.8 nM Bioactivity Info	TI LI LO TS
CP0460312 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C54H75N15O9S3	1
1	EC50 = 272.2 nM Bioactivity Info	TI LI LO TS
CP0951377 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C20H19ClN6O2	2
1	EC50 = 290 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1110 nM Bioactivity Info	TI LI LO TS
CP0409698 Compound Info	2-[(3S,6S,9S,12S,15R,20R,23S,26S)-15-amino-20-[[(2S,3S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]-3-benzyl-23-[(2S)-butan-2-yl]-9-[(1R)-1-hydroxyethyl]-6-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,22,25-heptaoxo-17,18-dithia-1,4,7,10,13,21,24-heptazabicyclo[24.3.0]nonacosan-12-yl]acetic acid Show/Hide	C55H77N13O13S2	1
1	EC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0903142 Compound Info	2-{1-[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C22H20F2N6O2	2
1	EC50 = 320 nM Bioactivity Info	TI LI LO TS
2	EC50 = 880 nM Bioactivity Info	TI LI LO TS
CP0958111 Compound Info	2-(2-(2-(1H-benzo[d]imidazol-2-yl)ethylamino)ethyl)-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl)thiazole-4-carboxamide Show/Hide	C23H24N6OS	2
1	EC50 = 325 nM Bioactivity Info	TI LI LO TS
2	EC50 = 620 nM Bioactivity Info	TI LI LO TS
CP0456166 Compound Info	(5R,8S,11S,14R,17S,20S)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-20-(3,3-diphenylpropanoylamino)-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide Show/Hide	C53H69N13O7S3	1
1	EC50 = 335.3 nM Bioactivity Info	TI LI LO TS
CP0534497 Compound Info	N-[(5R,8S,14S,17S,20R,23S,26S)-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(36),33(37),34-trien-5-yl]hexadecanamide Show/Hide	C73H106N14O8S3	1
1	EC50 = 369 nM Bioactivity Info	TI LI LO TS
CP0874586 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C21H22N6OS	2
1	EC50 = 387 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1720 nM Bioactivity Info	TI LI LO TS
CP0401063 Compound Info	N-[(2R)-1-[[(8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-trien-20-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]hexadecanamide Show/Hide	C68H99N13O7S3	1
1	EC50 = 458.3 nM Bioactivity Info	TI LI LO TS
CP0880273 Compound Info	2-(2-{[2-(5-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H20F2N6O2	2
1	EC50 = 460 nM Bioactivity Info	TI LI LO TS
2	EC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0874588 Compound Info	2-(2-{[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H20F2N6O2	2
1	EC50 = 460 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2120 nM Bioactivity Info	TI LI LO TS
CP0509271 Compound Info	(10R,13S,19S,22S,25R,28S,31S,34R)-10-acetamido-13,31-dibenzyl-22,28-bis[3-(diaminomethylideneamino)propyl]-11,14,20,23,26,29,32-heptaoxo-25-(sulfanylmethyl)-2-oxa-8,36-dithia-12,15,21,24,27,30,33-heptazatetracyclo[36.2.2.23,6.015,19]tetratetraconta-1(40),3(44),4,6(43),38,41-hexaene-34-carboxamide Show/Hide	C60H79N15O10S3	1
1	EC50 = 477.4 nM Bioactivity Info	TI LI LO TS
CP0903127 Compound Info	2-(2-{[2-(4-Chloro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H20ClFN6O2	2
1	EC50 = 490 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2340 nM Bioactivity Info	TI LI LO TS
CP0903122 Compound Info	2-(2-{[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H20F2N6OS	2
1	EC50 = 510 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0445524 Compound Info	(11R,14S,20S,23S,26R,29S,32S,35R)-11-acetamido-14,32-dibenzyl-23,29-bis[3-(diaminomethylideneamino)propyl]-12,15,21,24,27,30,33-heptaoxo-26-(sulfanylmethyl)-9,37-dithia-13,16,22,25,28,31,34-heptazatetracyclo[37.3.1.13,7.016,20]tetratetraconta-1(43),3(44),4,6,39,41-hexaene-35-carboxamide Show/Hide	C61H81N15O9S3	1
1	EC50 = 516.9 nM Bioactivity Info	TI LI LO TS
CP0874587 Compound Info	2-(2-{[2-(4,5-Difluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H19F3N6O2	2
1	EC50 = 518 nM Bioactivity Info	TI LI LO TS
2	EC50 = 636 nM Bioactivity Info	TI LI LO TS
CP0942115 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H18ClFN6OS	2
1	EC50 = 523 nM Bioactivity Info	TI LI LO TS
2	EC50 = 720 nM Bioactivity Info	TI LI LO TS
CP0904081 Compound Info	2-(2-{[2-(5-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H23Cl3F2N6OS	2
1	EC50 = 530 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0538411 Compound Info	2-[[2-[[(2S,3R)-1-[[(5R,8S,14S,17S,20R,23S,26S,29R)-8,26-dibenzyl-29-carbamoyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-trien-5-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]acetic acid Show/Hide	C60H85N17O13S3	1
1	EC50 = 531.7 nM Bioactivity Info	TI LI LO TS
CP0871743 Compound Info	2-{1-[2-(5-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide Show/Hide	C22H20F2N6O2	2
1	EC50 = 549 nM Bioactivity Info	TI LI LO TS
2	EC50 = 734 nM Bioactivity Info	TI LI LO TS
CP0903146 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide trihydrochloride Show/Hide	C21H25Cl3N6O2	2
1	EC50 = 571 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1230 nM Bioactivity Info	TI LI LO TS
CP0957855 Compound Info	2-(2-{[(4-fluoro-1H-1,3-benzodiazol-2-yl)methyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H18F2N6OS	2
1	EC50 = 582 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1122 nM Bioactivity Info	TI LI LO TS
CP0460314 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.2.2.010,14]heptatriaconta-1(36),33(37),34-triene-29-carboxamide Show/Hide	C54H75N15O9S3	1
1	EC50 = 585.6 nM Bioactivity Info	TI LI LO TS
CP0944108 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-5-methyl-1,3-thiazole-4-carboxamide Show/Hide	C22H23FN6OS	2
1	EC50 = 587 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2590 nM Bioactivity Info	TI LI LO TS
CP0905656 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H23Cl3F2N6OS	2
1	EC50 = 590 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2790 nM Bioactivity Info	TI LI LO TS
CP0456169 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.4.0.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C54H75N15O9S3	1
1	EC50 = 598.9 nM Bioactivity Info	TI LI LO TS
CP0903121 Compound Info	N-[(3-fluoropyridin-2-yl)methyl]-2-[2-({2-[4-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]ethyl}amino)ethyl]-1,3-oxazole-4-carboxamide Show/Hide	C22H20F4N6O2	2
1	EC50 = 628 nM Bioactivity Info	TI LI LO TS
2	EC50 = 736 nM Bioactivity Info	TI LI LO TS
CP0887766 Compound Info	2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide Show/Hide	C22H21FN6O2	2
1	EC50 = 630 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1030 nM Bioactivity Info	TI LI LO TS
CP0951417 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide Show/Hide	C20H20ClN7O	2
1	EC50 = 678 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1720 nM Bioactivity Info	TI LI LO TS
CP0909892 Compound Info	5-chloro-N-(pyridin-2-ylmethyl)-2-(2-{1,8,12-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8-tetraen-12-yl}ethyl)-1,3-thiazole-4-carboxamide Show/Hide	C22H21ClN6OS	2
1	EC50 = 679 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3100 nM Bioactivity Info	TI LI LO TS
CP0947240 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H19ClN6OS	2
1	EC50 = 689 nM Bioactivity Info	TI LI LO TS
2	EC50 = 760 nM Bioactivity Info	TI LI LO TS
CP0905660 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-[(3-chloropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H18Cl2N6OS	2
1	EC50 = 757 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1160 nM Bioactivity Info	TI LI LO TS
CP0946518 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide trihydrochloride Show/Hide	C20H22Cl3FN6O2	2
1	EC50 = 757 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1260 nM Bioactivity Info	TI LI LO TS
CP0874577 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H22Cl3FN6OS	2
1	EC50 = 810 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1450 nM Bioactivity Info	TI LI LO TS
CP0880284 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoro-6-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H21FN6OS	1
1	EC50 = 840 nM Bioactivity Info	TI LI LO TS
CP0880280 Compound Info	1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1H-pyrazole-4-carboxamide Show/Hide	C21H23N7O	2
1	EC50 = 885 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2620 nM Bioactivity Info	TI LI LO TS
CP0903755 Compound Info	1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1H-1,2,4-triazole-3-carboxamide Show/Hide	C20H21FN8O	2
1	EC50 = 930 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3720 nM Bioactivity Info	TI LI LO TS
CP0903753 Compound Info	2-(2-{[2-(4,6-Difluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H19F3N6O2	2
1	EC50 = 950 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1550 nM Bioactivity Info	TI LI LO TS
CP0909890 Compound Info	2-(2-(2-(1H-benzo[d]imidazol-2-yl)ethylamino)ethyl)-N-((3-fluoropyridin-2-yl)methyl)-5-methyloxazole-4-carboxamide Show/Hide	C22H23FN6O2	2
1	EC50 = 950 nM Bioactivity Info	TI LI LO TS
2	EC50 = 6380 nM Bioactivity Info	TI LI LO TS
CP0880267 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H25Cl3N6OS	2
1	EC50 = 1029 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1230 nM Bioactivity Info	TI LI LO TS
CP0960687 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl](cyclopropylmethyl)amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C25H27FN6OS	1
1	EC50 = 1050 nM Bioactivity Info	TI LI LO TS
CP0903762 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide Show/Hide	C21H21FN6OS	2
1	EC50 = 1130 nM Bioactivity Info	TI LI LO TS
2	EC50 = 10100 nM Bioactivity Info	TI LI LO TS
CP0947239 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C21H21ClN6OS	2
1	EC50 = 1188 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1600 nM Bioactivity Info	TI LI LO TS
CP0874579 Compound Info	2-(2-{[2-(5-cyano-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C22H20FN7O2	2
1	EC50 = 1196 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1998 nM Bioactivity Info	TI LI LO TS
CP0900251 Compound Info	2-{2-[(1H-1,3-benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide Show/Hide	C20H19FN6O2	2
1	EC50 = 1198 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1259 nM Bioactivity Info	TI LI LO TS
CP0903124 Compound Info	Benzyl N-(3-{[2-(1H-1,3-benzodiazol-2-yl)ethyl][2-(4-{[(3-fluoropyridin-2-yl)methyl]carbamoyl}-1,3-thiazol-2-yl)ethyl]amino}propyl)carbamate Show/Hide	C32H34FN7O3S	2
1	EC50 = 1207 nM Bioactivity Info	TI LI LO TS
2	EC50 = 25940 nM Bioactivity Info	TI LI LO TS
CP0880272 Compound Info	2-{1-[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide Show/Hide	C22H21FN6O2	2
1	EC50 = 1231 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2525 nM Bioactivity Info	TI LI LO TS
CP0909887 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide Show/Hide	C20H20FN7O	2
1	EC50 = 1245 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4700 nM Bioactivity Info	TI LI LO TS
CP0903109 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C20H19ClN6OS	2
1	EC50 = 1287 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1910 nM Bioactivity Info	TI LI LO TS
CP0954546 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-methoxypyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H22N6O2S	1
1	EC50 = 1380 nM Bioactivity Info	TI LI LO TS
CP0874583 Compound Info	1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Show/Hide	C22H21F4N7O	2
1	EC50 = 1412 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4370 nM Bioactivity Info	TI LI LO TS
CP0957856 Compound Info	2-(2-{[2-(4,7-Difluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H19F3N6O2	2
1	EC50 = 1420 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2270 nM Bioactivity Info	TI LI LO TS
CP0946468 Compound Info	2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-chloropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H21ClN6OS	2
1	EC50 = 1459 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3550 nM Bioactivity Info	TI LI LO TS
CP0874590 Compound Info	1-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide Show/Hide	C22H22FN7O	2
1	EC50 = 1462 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2840 nM Bioactivity Info	TI LI LO TS
CP0951409 Compound Info	N-[(3-fluoropyridin-2-yl)methyl]-2-(2-{[2-(4-methoxy-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-1,3-oxazole-4-carboxamide Show/Hide	C22H23FN6O3	2
1	EC50 = 1580 nM Bioactivity Info	TI LI LO TS
2	EC50 = 24900 nM Bioactivity Info	TI LI LO TS
CP0905659 Compound Info	2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide Show/Hide	C22H22N6O2	2
1	EC50 = 1608 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2760 nM Bioactivity Info	TI LI LO TS
CP0944213 Compound Info	2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-(pyridazin-3-ylmethyl)-1,3-oxazole-4-carboxamide Show/Hide	C21H21N7O2	2
1	EC50 = 1690 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3860 nM Bioactivity Info	TI LI LO TS
CP0880271 Compound Info	N-[(3-Fluoropyridin-2-yl)methyl]-2-(1-{2-[7-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]ethyl}azetidin-3-yl)-1,3-oxazole-4-carboxamide Show/Hide	C23H20F4N6O2	2
1	EC50 = 1721 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3604 nM Bioactivity Info	TI LI LO TS
CP0941149 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(2-cyanophenyl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H20N6OS	1
1	EC50 = 1790 nM Bioactivity Info	TI LI LO TS
CP0941164 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(5-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H22N6OS	1
1	EC50 = 1810 nM Bioactivity Info	TI LI LO TS
CP0901638 Compound Info	2-(2-{[(4-fluoro-1H-1,3-benzodiazol-2-yl)methyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C20H18F2N6O2	2
1	EC50 = 1828 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3176 nM Bioactivity Info	TI LI LO TS
CP0900252 Compound Info	2-{1-[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide Show/Hide	C22H20F2N6O2	2
1	EC50 = 1840 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3170 nM Bioactivity Info	TI LI LO TS
CP0955513 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloro-5-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H18ClFN6OS	1
1	EC50 = 1850 nM Bioactivity Info	TI LI LO TS
CP0903128 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C20H20ClN7OS	2
1	EC50 = 1850 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3580 nM Bioactivity Info	TI LI LO TS
CP0903751 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-4-methyl-1,3-thiazole-5-carboxamide Show/Hide	C22H23FN6OS	2
1	EC50 = 1890 nM Bioactivity Info	TI LI LO TS
2	EC50 = 12900 nM Bioactivity Info	TI LI LO TS
CP0874589 Compound Info	2-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C20H19FN6O2	2
1	EC50 = 2072 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3260 nM Bioactivity Info	TI LI LO TS
CP0850093 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3,5-dimethylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H24N6OS	1
1	EC50 = 2110 nM Bioactivity Info	TI LI LO TS
CP0903125 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-5-methyl-1,3-thiazole-4-carboxamide Show/Hide	C21H21FN6OS	2
1	EC50 = 2110 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3207 nM Bioactivity Info	TI LI LO TS
CP0944214 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1H-pyrazole-4-carboxamide Show/Hide	C22H23N7O	2
1	EC50 = 2148 nM Bioactivity Info	TI LI LO TS
2	EC50 = 13940 nM Bioactivity Info	TI LI LO TS
CP0874580 Compound Info	2-(2-{[2-(4-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide Show/Hide	C21H21FN6O2	2
1	EC50 = 2160 nM Bioactivity Info	TI LI LO TS
2	EC50 = 12720 nM Bioactivity Info	TI LI LO TS
CP0951408 Compound Info	2-(2-{[2-(7-Chloro-4-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide Show/Hide	C21H19ClF2N6O2	2
1	EC50 = 2180 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3150 nM Bioactivity Info	TI LI LO TS
CP0944105 Compound Info	2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H20ClFN6OS	2
1	EC50 = 2440 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3380 nM Bioactivity Info	TI LI LO TS
CP0903144 Compound Info	1-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1H-pyrazole-4-carboxamide Show/Hide	C24H25N7O	2
1	EC50 = 2512 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8380 nM Bioactivity Info	TI LI LO TS
CP0944109 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(4,6-dimethylpyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H24N6OS	1
1	EC50 = 2630 nM Bioactivity Info	TI LI LO TS
CP0874594 Compound Info	2-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H22Cl3FN6OS	2
1	EC50 = 2690 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4908 nM Bioactivity Info	TI LI LO TS
CP0903748 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C22H25Cl3N6OS	1
1	EC50 = 2900 nM Bioactivity Info	TI LI LO TS
CP0903132 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1,3-thiazole-4-carboxamide Show/Hide	C21H18ClF3N6OS	1
1	EC50 = 2920 nM Bioactivity Info	TI LI LO TS
CP0905657 Compound Info	2-(2-{[(6-Fluoro-1H-1,3-benzodiazol-2-yl)methyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H21Cl3F2N6OS	2
1	EC50 = 2956 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4450 nM Bioactivity Info	TI LI LO TS
CP0903123 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)-2-methylpropyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C23H25FN6OS	2
1	EC50 = 2966 nM Bioactivity Info	TI LI LO TS
2	EC50 = 5700 nM Bioactivity Info	TI LI LO TS
CP0854890 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(5,6,7,8-tetrahydroquinolin-8-yl)-1,3-thiazole-4-carboxamide Show/Hide	C23H24N6OS	1
1	EC50 = 2980 nM Bioactivity Info	TI LI LO TS
CP0904080 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H24Cl3N7OS	2
1	EC50 = 3015 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4330 nM Bioactivity Info	TI LI LO TS
CP0909889 Compound Info	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(2-{[2-(5-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H22Cl3F3N6OS	2
1	EC50 = 3040 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4507 nM Bioactivity Info	TI LI LO TS
CP0909891 Compound Info	2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1,3-thiazole-4-carboxamide Show/Hide	C24H24N6OS	2
1	EC50 = 3220 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8050 nM Bioactivity Info	TI LI LO TS
CP0880276 Compound Info	2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H21FN6OS	2
1	EC50 = 3640 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3946 nM Bioactivity Info	TI LI LO TS
CP0903110 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl](methyl)amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C22H26Cl3FN6OS	2
1	EC50 = 3775 nM Bioactivity Info	TI LI LO TS
2	EC50 = 13470 nM Bioactivity Info	TI LI LO TS
CP0905658 Compound Info	3-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1-methyl-1H-pyrazole-5-carboxamide Show/Hide	C21H22FN7O	2
1	EC50 = 3820 nM Bioactivity Info	TI LI LO TS
2	EC50 = 17000 nM Bioactivity Info	TI LI LO TS
CP0887767 Compound Info	4-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-2-carboxamide Show/Hide	C20H19FN6OS	2
1	EC50 = 3830 nM Bioactivity Info	TI LI LO TS
2	EC50 = 11115 nM Bioactivity Info	TI LI LO TS
CP0909893 Compound Info	2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(5-methylpyrimidin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H26Cl3N7OS	2
1	EC50 = 3954 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8170 nM Bioactivity Info	TI LI LO TS
CP0957783 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1H-1,2,4-triazole-3-carboxamide Show/Hide	C19H19ClN8O	1
1	EC50 = 3960 nM Bioactivity Info	TI LI LO TS
CP0909886 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(6-methylpyridazin-3-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H26Cl3N7OS	2
1	EC50 = 3960 nM Bioactivity Info	TI LI LO TS
2	EC50 = 7730 nM Bioactivity Info	TI LI LO TS
CP0946477 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-methylpyridin-4-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H25Cl3N6OS	1
1	EC50 = 4030 nM Bioactivity Info	TI LI LO TS
CP0874592 Compound Info	2-{3-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]propyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C21H24Cl3FN6OS	2
1	EC50 = 4090 nM Bioactivity Info	TI LI LO TS
2	EC50 = 5194 nM Bioactivity Info	TI LI LO TS
CP0957785 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H18F2N6OS	1
1	EC50 = 4120 nM Bioactivity Info	TI LI LO TS
CP0903129 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1H-1,2,4-triazole-3-carboxamide Show/Hide	C19H19FN8O	2
1	EC50 = 4121 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8230 nM Bioactivity Info	TI LI LO TS
CP0874578 Compound Info	2-[(1R,5S,6S)-3-(1H-1,3-Benzodiazol-2-ylmethyl)-3-azabicyclo[3.1.0]hexan-6-yl]-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C23H24Cl3FN6OS	1
1	EC50 = 4140 nM Bioactivity Info	TI LI LO TS
CP0909885 Compound Info	2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-3-hydroxyazetidin-3-yl}-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H20ClFN6O2S	2
1	EC50 = 4430 nM Bioactivity Info	TI LI LO TS
2	EC50 = 6100 nM Bioactivity Info	TI LI LO TS
CP0874593 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H24Cl3N7OS	2
1	EC50 = 4464 nM Bioactivity Info	TI LI LO TS
2	EC50 = 10560 nM Bioactivity Info	TI LI LO TS
CP0951422 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-imidazol-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C19H21N7OS	1
1	EC50 = 4530 nM Bioactivity Info	TI LI LO TS
CP0942112 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-5-(trifluoromethyl)-1,3-thiazole-4-carboxamide Show/Hide	C22H20F4N6OS	2
1	EC50 = 4940 nM Bioactivity Info	TI LI LO TS
2	EC50 = 5059 nM Bioactivity Info	TI LI LO TS
CP0941165 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-4-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H19FN6OS	1
1	EC50 = 5050 nM Bioactivity Info	TI LI LO TS
CP0960686 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C19H18ClN7OS	2
1	EC50 = 5300 nM Bioactivity Info	TI LI LO TS
2	EC50 = 17180 nM Bioactivity Info	TI LI LO TS
CP0887763 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridine-2-ylmethyl)-1,3-oxazole-4-carboxamid Show/Hide	C20H20N6O2	2
1	EC50 = 5750 nM Bioactivity Info	TI LI LO TS
2	EC50 = 11073 nM Bioactivity Info	TI LI LO TS
CP0871769 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[2-(morpholine-4-sulfonyl)phenyl]methyl}-1,3-thiazole-4-carboxamide Show/Hide	C25H28N6O4S2	1
1	EC50 = 6000 nM Bioactivity Info	TI LI LO TS
CP0903147 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H23N7OS	1
1	EC50 = 6560 nM Bioactivity Info	TI LI LO TS
CP0942113 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-[(5-methylpyrimidin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H22ClN7OS	2
1	EC50 = 6840 nM Bioactivity Info	TI LI LO TS
2	EC50 = 23692 nM Bioactivity Info	TI LI LO TS
CP0954513 Compound Info	2-{2-[(3-Aminopropyl)[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C24H28FN7OS	1
1	EC50 = 7411 nM Bioactivity Info	TI LI LO TS
CP0938647 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl](butyl)amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C25H29FN6OS	1
1	EC50 = 7862 nM Bioactivity Info	TI LI LO TS
CP0854891 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[3-(trifluoromethyl)pyridin-2-yl]methyl}-1,3-thiazole-4-carboxamide Show/Hide	C21H19F3N6OS	1
1	EC50 = 7920 nM Bioactivity Info	TI LI LO TS
CP0903750 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H23Cl3N6OS	1
1	EC50 = 8270 nM Bioactivity Info	TI LI LO TS
CP0957776 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]-2-methylpropyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C22H23FN6OS	1
1	EC50 = 8330 nM Bioactivity Info	TI LI LO TS
CP0877275 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(6-cyanopyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H19N7OS	1
1	EC50 = 10380 nM Bioactivity Info	TI LI LO TS
CP0953916 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[2-(4-methylpiperazin-1-yl)phenyl]methyl}-1,3-thiazole-4-carboxamide Show/Hide	C26H31N7OS	1
1	EC50 = 10400 nM Bioactivity Info	TI LI LO TS
CP0880279 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide Show/Hide	C21H19F4N7O	2
1	EC50 = 12110 nM Bioactivity Info	TI LI LO TS
2	EC50 = 16130 nM Bioactivity Info	TI LI LO TS
CP0903756 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C19H18ClN7OS	1
1	EC50 = 12452 nM Bioactivity Info	TI LI LO TS
CP0903108 Compound Info	4-(2-{[2-(1H-1,3-Benzodiazol-2-yl)-2,2-difluoroethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-2-carboxamide Show/Hide	C21H19F3N6OS	2
1	EC50 = 12720 nM Bioactivity Info	TI LI LO TS
2	EC50 = 24845 nM Bioactivity Info	TI LI LO TS
CP0880283 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-pyrazol-5-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C19H21N7OS	1
1	EC50 = 13080 nM Bioactivity Info	TI LI LO TS
CP0887769 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-imidazol-5-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C19H21N7OS	1
1	EC50 = 13150 nM Bioactivity Info	TI LI LO TS
CP0944236 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C19H19N7OS	1
1	EC50 = 16560 nM Bioactivity Info	TI LI LO TS
CP0903145 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-5-(trifluoromethyl)-1,3-thiazole-4-carboxamide Show/Hide	C21H18F4N6OS	1
1	EC50 = 16985 nM Bioactivity Info	TI LI LO TS
CP0903134 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridin-2-ylmethyl)-1H-pyrazole-4-carboxamide Show/Hide	C20H21N7O	1
1	EC50 = 17780 nM Bioactivity Info	TI LI LO TS
CP0942116 Compound Info	1-[1-(1H-1,3-Benzodiazol-2-ylmethyl)azetidin-3-yl]-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide Show/Hide	C21H20FN7O	2
1	EC50 = 17860 nM Bioactivity Info	TI LI LO TS
2	EC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0874540 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyrimidin-4-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C19H19N7OS	1
1	EC50 = 18310 nM Bioactivity Info	TI LI LO TS
CP0948408 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(1,3-oxazol-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C18H18N6O2S	1
1	EC50 = 18690 nM Bioactivity Info	TI LI LO TS
CP0941162 Compound Info	2-{3-[(1H-1,3-Benzodiazol-2-yl)amino]propyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H19FN6OS	2
1	EC50 = 20000 nM Bioactivity Info	TI LI LO TS
2	EC50 = 21210 nM Bioactivity Info	TI LI LO TS
CP0874585 Compound Info	2-{2-[(1H-1,3-Benzodiazol-5-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H19FN6OS	1
1	EC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0909888 Compound Info	2-{2-[(1H-1,3-Benzodiazol-5-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide 2-{2-[(1H-1,3-Benzodiazol-4-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H19FN6OS	1
1	EC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0903133 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(6-methylpyridazin-3-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H21N7OS	1
1	EC50 = 20550 nM Bioactivity Info	TI LI LO TS
CP0874582 Compound Info	2-{2-[bis(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C28H25FN8OS	1
1	EC50 = 22000 nM Bioactivity Info	TI LI LO TS
CP0874595 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-pyrazol-3-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C19H21N7OS	1
1	EC50 = 22340 nM Bioactivity Info	TI LI LO TS
CP0880281 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(2-methylpyridin-4-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H22N6OS	1
1	EC50 = 22800 nM Bioactivity Info	TI LI LO TS
CP0887765 Compound Info	1-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]carbamoyl}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide dihydrochloride Show/Hide	C21H22Cl2FN7O2	1
1	EC50 = 25000 nM Bioactivity Info	TI LI LO TS
CP0959235 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(5-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C20H19FN6OS	1
1	EC50 = 30950 nM Bioactivity Info	TI LI LO TS
CP0903681 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(2-fluorophenyl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H20FN5OS	1
1	EC50 = 32330 nM Bioactivity Info	TI LI LO TS
CP0880277 Compound Info	2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-methyl-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C21H23N7OS	2
1	EC50 = 35985 nM Bioactivity Info	TI LI LO TS
2	EC50 = 39070 nM Bioactivity Info	TI LI LO TS
CP0903141 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(6-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide Show/Hide	C21H22N6OS	1
1	EC50 = 36260 nM Bioactivity Info	TI LI LO TS
CP0904108 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C19H19N7OS	1
1	EC50 = 37460 nM Bioactivity Info	TI LI LO TS
CP0912267 Compound Info	2-{2-[(1,3-Benzoxazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride Show/Hide	C20H21Cl3FN5O2S	1
1	EC50 = 38250 nM Bioactivity Info	TI LI LO TS
CP0874576 Compound Info	2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyrazin-2-ylmethyl)-1,3-thiazole-4-carboxamide Show/Hide	C19H19N7OS	1
1	EC50 = 38670 nM Bioactivity Info	TI LI LO TS
CP0903126 Compound Info	1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-3,5-dimethyl-1H-pyrazole-4-carboxamide Show/Hide	C22H24FN7O	1
1	EC50 = 39745 nM Bioactivity Info	TI LI LO TS
CP0954514 Compound Info	2-{2-[2-(1H-1,3-Benzodiazol-2-yl)acetamido]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide dihydrochloride Show/Hide	C21H21Cl2FN6O2S	1
1	EC50 = 41330 nM Bioactivity Info	TI LI LO TS
CP0401015 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28,37-octazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C53H74N16O9S3	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0401062 Compound Info	N-[(2S)-1-[[(8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-trien-20-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]hexadecanamide Show/Hide	C68H99N13O7S3	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0413867 Compound Info	(3S,6R,19R,22S,25S,28R,31S,34S)-6-acetamido-3,22-dibenzyl-25,31-bis[3-(diaminomethylideneamino)propyl]-2,5,10,15,21,24,27,30,33-nonaoxo-28-(sulfanylmethyl)-8,17-dithia-1,4,11,14,20,23,26,29,32-nonazabicyclo[32.3.0]heptatriacontane-19-carboxamide Show/Hide	C52H77N17O11S3	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0456830 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-5-(hexadecanoylamino)-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide Show/Hide	C74H107N15O9S3	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0460309 Compound Info	(7R,10S,16S,19S,22R,25S,31R,34S,40S,43S,46R,49S,52S,55R)-7-acetamido-10,28,34,52-tetrabenzyl-19,25,43,49-tetrakis(3-carbamimidamidopropyl)-8,11,17,20,23,26,29,32,35,41,44,47,50,53-tetradecaoxo-22,46-bis(sulfanylmethyl)-5,57,62-trithia-9,12,18,21,24,27,30,33,36,42,45,48,51,54-tetradecazapentacyclo[29.29.3.13,59.012,16.036,40]tetrahexaconta-1,3(64),59-triene-55-carboxamide Show/Hide	C96H134N28O16S5	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0477256 Compound Info	(3S,6R,11R,14S,17S,20R,23S,26S)-6-acetamido-3,14-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-2,5,13,16,19,22,25-heptaoxo-20-(sulfanylmethyl)-8,9-dithia-1,4,12,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-11-carboxamide Show/Hide	C46H67N15O9S3	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0482720 Compound Info	(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatetracyclo[31.7.1.010,14.037,41]hentetraconta-1(40),33,35,37(41),38-pentaene-29-carboxamide Show/Hide	C58H77N15O9S3	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0482721 Compound Info	(3S,6R,16R,19S,22S,25R,28S,31S)-6-acetamido-3,19-dibenzyl-22,28-bis[3-(diaminomethylideneamino)propyl]-2,5,11,11,18,21,24,27,30-nonaoxo-25-(sulfanylmethyl)-8,11lambda6,14-trithia-1,4,17,20,23,26,29-heptazabicyclo[29.3.0]tetratriacontane-16-carboxamide Show/Hide	C50H75N15O11S4	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS
CP0961591 Compound Info	(8R,11S,17S,20S,23R,26S,29S,32R,35S,41S,44S,47R,50S,53S,56R,59S,65S,68R,71R,74S,77S,80R)-8-acetamido-11,29,35,53,59,77-hexabenzyl-20,26,44,50,68,74-hexakis(3-carbamimidamidopropyl)-4,9,12,18,21,24,27,30,33,36,42,45,48,51,54,57,60,66,69,72,75,78,84,89,96-pentacosaoxo-23,47,71-tris(sulfanylmethyl)-3,85,88,97-tetraoxa-6,82,91,94-tetrathia-10,13,19,22,25,28,34,37,43,46,49,52,55,58,61,67,70,73,76,79-icosazahexacyclo[54.30.6.61,32.013,17.037,41.061,65]octanonacontane-80-carboxamide Show/Hide	C142H200N40O31S7	1
1	EC50 > 600 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000031 , MDCK

Cell Line Info

Cell Line ID: CL000078 , T-47D

Cell Line Info

Clinical Information about the Protein

Target 1 ( Solute carrier family 40 member 1 (SLC40A1) )

Target Type	Clinical trial Target

Similar Protein(s) and Bioactivity Statistics

50% Identity

Protein ID	Protein Name	Protein Organism
PT06354	Solute carrier family 40 member 1	Mus musculus, Mouse	Protein Info

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han