Brief Information of the Cell Line and Protein
Cell Line ID: CL000078 , T-47D
Synonyms
T-47-D
T47-D
T47D:A
T47D
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0553
Protein ID: PT00889 , Estrogen receptor beta
Gene Name ESR2
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q92731
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000078  Protein ID: PT00889
 
Compound ID Compound Name Compound Formula
CP0006292
(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol
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C18H24O2
 1
1
EC50 = 0.8 nM
   TI
   LI
   LO
   TS
CP0113654
4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[4-(2-methyl-thiazol-4-ylmethyl)-piperazin-1-yl]-[1,3,5]triazin-2-ylamino}-ethyl)-phenol
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C30H37ClN8OS
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0220522
4-[2-(4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol
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C25H32ClN7O
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0217788
4-(2-{4-[3-(4-Chloro-phenyl)-propylsulfanyl]-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino}-ethyl)-phenol
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C24H29ClN6OS
 1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CP0041761
2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol
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C28H27NO4S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0237075
4-(2-{4-{[3-(4-Chloro-phenyl)-propyl]-methyl-amino}-6-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-[1,3,5]triazin-2-ylamino}-ethyl)-phenol
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C27H36ClN7O2
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0292305
4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino}-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino)-ethyl]-phenol
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C25H32FN7O
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0087464
4-[2-[[4-[methyl-[[(1R,2S)-2-phenylcyclopropyl]methyl]amino]-6-piperazin-1-yl-1,3,5-triazin-2-yl]amino]ethyl]phenol
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C26H33N7O
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS