| Compound ID |
Compound Name |
Compound Formula |
|
CP0247831
|
4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C18H16Cl2N6
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0269827
|
4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3-yl)propyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C20H19Cl2N5
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0198842
|
4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)propyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H18Cl2N6
|
1
|
| 1 |
EC50 = 0.04 nM
|
|
|
|
CP0198843
|
4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3-yl)butyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C21H21Cl2N5
|
1
|
| 1 |
EC50 = 0.05 nM
|
|
|
|
CP0041416
|
(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione
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|
C24H34O4
|
6
|
| 1 |
EC50 = 0.1 nM
|
|
|
| 2 |
EC50 = 0.12 nM
|
|
|
| 3 |
EC50 = 0.33 nM
|
|
|
| 4 |
EC50 = 0.4 nM
|
|
|
| 5 |
EC50 = 0.5 nM
|
|
|
| 6 |
IC50 = 10.8 nM
|
|
|
|
CP0426987
|
5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C18H18N4S
|
2
|
| 1 |
EC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
|
CP0151286
|
(S)-methyl 3-((3-chloro-4-cyanophenyl)(2-chlorobenzyl)amino)pyrrolidine-1-carboxylate
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|
C20H19Cl2N3O2
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0038813
|
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
Show/Hide
|
C21H30O2
|
6
|
| 1 |
EC50 = 0.1 nM
|
|
|
| 2 |
EC50 = 0.9 nM
|
|
|
| 3 |
EC50 = 0.92 nM
|
|
|
| 4 |
EC50 = 1.8 nM
|
|
|
| 5 |
EC50 = 2.2 nM
|
|
|
| 6 |
IC50 = 3.5 nM
|
|
|
|
CP0281148
|
TANAPROGET
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|
C16H15N3OS
|
2
|
| 1 |
EC50 = 0.15 nM
|
|
|
| 2 |
IC50 = 0.5 nM
|
|
|
|
CP0502680
|
4-Methyl-5-(2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H18N2OS
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 8.1 nM
|
|
|
|
CP0377971
|
6-(3-chlorophenyl)-4-methyl-4-prop-2-enyl-1H-3,1-benzoxazine-2-thione
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|
C18H16ClNOS
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0461349
|
4-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)thiophene-2-carbonitrile
Show/Hide
|
C18H16N2S2
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0108673
|
(S)-2-chloro-4-((2-chloro-5-fluorobenzyl)(1-ethyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C20H18Cl2FN3O
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0275351
|
(S)-2-chloro-4-((2-chlorobenzyl)(1-methyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C19H17Cl2N3O
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0289717
|
(S)-2-chloro-4-((2-chlorobenzyl)(1-isopropyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
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|
C21H21Cl2N3O
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0376523
|
(1S,12S,15S,20R)-15-hydroxy-1,16,16,20-tetramethyl-3-azapentacyclo[10.8.0.02,10.04,9.015,20]icosa-2(10),4,6,8-tetraen-17-one
Show/Hide
|
C23H29NO2
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0460079
|
4-(2,4,4-Trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C16H16N2OS
|
2
|
| 1 |
EC50 = 0.35 nM
|
|
|
| 2 |
IC50 = 11.5 nM
|
|
|
|
CP0463687
|
3-Fluoro-5-(2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
|
C18H17FN2O
|
2
|
| 1 |
EC50 = 0.35 nM
|
|
|
| 2 |
IC50 = 7.3 nM
|
|
|
|
CP0378000
|
3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-5'-yl)benzonitrile
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|
C20H17FN2S
|
2
|
| 1 |
EC50 = 0.36 nM
|
|
|
| 2 |
IC50 = 15.9 nM
|
|
|
|
CP0036643
|
4-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C15H12N2OS2
|
2
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0538948
|
3-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)benzonitrile
Show/Hide
|
C17H14N2OS
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0122636
|
5-(5-(furan-2-yl)-5-methyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C20H17N3O3
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0180139
|
(S)-4-((2-bromobenzyl)(1-propionylpyrrolidin-3-yl)amino)-2-chlorobenzonitrile
Show/Hide
|
C21H21BrClN3O
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0497927
|
5-(3-chloro-5-fluorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H17ClFNS
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0555070
|
4-methyl-5-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)thiophene-2-carbonitrile
Show/Hide
|
C19H18N2S2
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0466776
|
5-((5R)-5-methyl-2-oxo-5-(thiophen-3-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H15N3O2S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0427365
|
5-(3-cyclobutyl-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C17H16N4S
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0201399
|
4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H17Cl2N5
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0476645
|
3-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)-5-fluorobenzonitrile
Show/Hide
|
C17H13FN2OS
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0102797
|
4-((2-chlorobenzyl)(1-(1-methyl-1H-imidazol-2-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C20H18Cl2N4
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0108764
|
4-((2-chlorobenzyl)(1-(1-ethyl-1H-tetrazol-5-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H18Cl2N6
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0514908
|
5-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)thiophene-2-carbonitrile
Show/Hide
|
C15H12N2OS2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0384482
|
5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H15N3O2S
|
2
|
| 1 |
EC50 = 0.7 nM
|
|
|
| 2 |
IC50 = 3.8 nM
|
|
|
|
CP0295352
|
2-((2-chlorobenzyl)(3-chloro-4-cyanophenyl)amino)-N,N-dimethylpropanamide
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|
C19H19Cl2N3O
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0483657
|
4-(4,4-Dimethyl-2-trifluoromethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C16H13F3N2OS
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
|
CP0539780
|
5-(3,5-difluorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
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|
C19H17F2NS
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0062469
|
1-methyl-5-(5-methyl-2-oxo-5-(thiophen-3-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C20H17N3O2S
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 3.4 nM
|
|
|
|
CP0384484
|
1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C20H17N3O2S
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 2.4 nM
|
|
|
|
CP0322353
|
(S)-2-chloro-4-((2,5-dichlorobenzyl)(1-ethyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C20H18Cl3N3O
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0367570
|
(S)-2-chloro-4-((1-ethyl-5-oxopyrrolidin-3-yl)(2-methylbenzyl)amino)benzonitrile
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0376416
|
2,2-Dimethyl-propionic acid 6-(5-cyano-thiophen-3-yl)-4,4-dimethyl-2-trifluoromethyl-4H-benzo[d][1,3]oxazin-1-ylmethyl ester
Show/Hide
|
C22H23F3N2O3S
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 7.9 nM
|
|
|
|
CP0517112
|
6-(3-chloro-5-fluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H13ClFNOS
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0468063
|
6-(3-fluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H14FNOS
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0530163
|
5-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)thiophene-2-carbonitrile
Show/Hide
|
C18H16N2S2
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0454953
|
5-[3-(1-ethylpropyl)-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl]-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C18H20N4S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0268771
|
(S)-2-chloro-4-((2-chlorobenzyl)(1-(methylsulfonyl)pyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C19H19Cl2N3O2S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0506560
|
5-(1-hydroxy-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0430157
|
5-(2,4,4-Trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C16H16N2OS
|
2
|
| 1 |
EC50 = 1.05 nM
|
|
|
| 2 |
IC50 = 27 nM
|
|
|
|
CP0375431
|
4,4-dimethyl-6-(3-nitrophenyl)-1H-3,1-benzoxazine-2-thione
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|
C16H14N2O3S
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0384481
|
5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C16H15N3O2
|
3
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
| 3 |
IC50 > 3000 nM
|
|
|
|
CP0484795
|
5-(5-methyl-2-oxo-5-(thiophen-3-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H15N3O2S
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0376524
|
(1S,12S,15S,17R,20R)-1,16,16,20-tetramethyl-3-azapentacyclo[10.8.0.02,10.04,9.015,20]icosa-2(10),4,6,8-tetraene-15,17-diol
Show/Hide
|
C23H31NO2
|
3
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 5.5 nM
|
|
|
| 3 |
IC50 = 57.3 nM
|
|
|
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CP0454763
|
4-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)furan-2-carbonitrile
Show/Hide
|
C15H12N2O2S
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0476702
|
5-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)furan-2-carbonitrile
Show/Hide
|
C15H12N2O2S
|
1
|
| 1 |
EC50 = 1.25 nM
|
|
|
|
CP0500698
|
5-(7-fluoro-2-oxospiro[1H-indole-3,1'-cyclohexane]-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C19H18FN3O
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 3.6 nM
|
|
|
|
CP0073413
|
4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C21H22Cl2N6
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0460531
|
4-fluoro-3-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)benzonitrile
Show/Hide
|
C20H17FN2S
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0540997
|
5-(5-chlorothiophen-2-yl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C17H16ClNS2
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0438866
|
6-(3,5-difluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H13F2NOS
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0453291
|
6-(2,3-difluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H13F2NOS
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0511377
|
5-(3-fluorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H18FNS
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0538914
|
5-(3-chlorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H18ClNS
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0454787
|
3-(4,4-Dimethyl-2-trifluoromethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
|
C18H14F4N2O
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 7.1 nM
|
|
|
|
CP0453293
|
6-(3-bromo-5-fluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H13BrFNOS
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0479801
|
6-(3-chlorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H14ClNOS
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0466306
|
5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1-ethyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C17H17N3O2
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
IC50 ~ 3000 nM
|
|
|
|
CP0527154
|
5-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)furan-2-carbonitrile
Show/Hide
|
C18H16N2OS
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0535267
|
4-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)furan-2-carbonitrile
Show/Hide
|
C18H16N2OS
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0404869
|
3-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)benzonitrile
Show/Hide
|
C20H18N2S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0152601
|
(S)-2-chloro-4-((1-isopropyl-5-oxopyrrolidin-3-yl)(2-methylbenzyl)amino)benzonitrile
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0397196
|
5-(1-ethyl-1-hydroxy-3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0430214
|
5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C15H13N3O2
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
IC50 > 3000 nM
|
|
|
|
CP0181678
|
(S)-2-chloro-4-((2-methylbenzyl)(1-propionylpyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0433191
|
1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-dihydro-1'H-indole)]-5-yl]-1H-2-pyrrolecarbonitrile
Show/Hide
|
C19H19N3O
|
4
|
| 1 |
EC50 = 2.3 nM
|
|
|
| 2 |
EC50 = 2.8 nM
|
|
|
| 3 |
IC50 = 3.3 nM
|
|
|
| 4 |
IC50 > 3000 nM
|
|
|
|
CP0400953
|
6-(3-Chloro-phenyl)-2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine
Show/Hide
|
C17H18ClNO
|
2
|
| 1 |
EC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0437095
|
4-methyl-5-(2-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,1'-cyclohexan]-6-yl)thiophene-2-carbonitrile
Show/Hide
|
C20H22N2OS
|
2
|
| 1 |
EC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 2.9 nM
|
|
|
|
CP0460727
|
3-(2-sulfanylidenespiro[1H-3,1-benzoxazine-4,1'-cyclohexane]-6-yl)benzonitrile
Show/Hide
|
C20H18N2OS
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0511451
|
6-(3-bromophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H14BrNOS
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0544879
|
6-[3-fluoro-5-(trifluoromethyl)phenyl]-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C17H13F4NOS
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0497032
|
5-(3-hydroxyphenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H19NOS
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0460881
|
6-(3-Fluoro-phenyl)-2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine
Show/Hide
|
C17H18FNO
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0377877
|
6-(3-fluoro-5-methoxyphenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C17H16FNO2S
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0497033
|
5-(3-fluoro-5-methoxyphenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C20H20FNOS
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0454950
|
3-(3-cyclobutyl-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl)-5-fluorobenzonitrile
Show/Hide
|
C18H14FN3S
|
1
|
| 1 |
EC50 = 2.7 nM
|
|
|
|
CP0298530
|
(-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]hept-2-yl)-2,2,4-trimethyl 2,5-dihydro-(1H)-6-oxa-1-aza-chrysen
Show/Hide
|
C26H27F2NO2
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0487626
|
6-(3-Chloro-phenyl)-4,4-dimethyl-2-trifluoromethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine
Show/Hide
|
C17H15ClF3NO
|
2
|
| 1 |
EC50 = 2.9 nM
|
|
|
| 2 |
IC50 = 41.3 nM
|
|
|
|
CP0295176
|
2-chloro-4-((cyclohexylmethyl)(1-(4-methyl-4H-1,2,4-triazol-3-yl)ethyl)amino)benzonitrile
Show/Hide
|
C19H24ClN5
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0180142
|
2-chloro-4-(((S)-1-((S)-2-hydroxypropanoyl)pyrrolidin-3-yl)(2-methylbenzyl)amino)benzonitrile
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0268770
|
(S)-4-((2-bromobenzyl)(1-(methylsulfonyl)pyrrolidin-3-yl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H19BrClN3O2S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0401543
|
5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0529595
|
5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C16H15N3O2
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
IC50 = 10.7 nM
|
|
|
|
CP0398928
|
4-(2-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,1'-cyclohexan]-6-yl)thiophene-2-carbonitrile
Show/Hide
|
C19H20N2OS
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 12 nM
|
|
|
|
CP0235436
|
4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)butyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C22H23Cl2N5
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0180138
|
(S)-methyl 3-((3-chloro-4-cyanophenyl)(2-methylbenzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
|
C21H22ClN3O2
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0466364
|
2-fluoro-5-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)benzonitrile
Show/Hide
|
C20H17FN2S
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0509647
|
5-(3-chloro-4-fluorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H17ClFNS
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0102804
|
4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C20H19Cl2N5
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
|
CP0469557
|
4-(2,4,4-Trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-furan-2-carbonitrile
Show/Hide
|
C16H16N2O2
|
2
|
| 1 |
EC50 = 4.55 nM
|
|
|
| 2 |
IC50 = 113.4 nM
|
|
|
|
CP0063871
|
9-Fluoro-2,2,4-trimethyl-5-[1-(3-methyl-pyridin-4-yl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C26H23FN2O
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0529765
|
4,4-diethyl-6-(3-nitrophenyl)-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C18H18N2O3S
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0226071
|
4-((2-chlorobenzyl)(2-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)propyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C21H21Cl2N5
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0361748
|
9-Fluoro-2,2,4-trimethyl-5-[1-pyridin-4-yl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C25H21FN2O
|
1
|
| 1 |
EC50 = 4.9 nM
|
|
|
|
CP0530700
|
5-(3-chlorophenyl)-3,3-dimethyl-1H-indole-2-thione
Show/Hide
|
C16H14ClNS
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0461443
|
5-(2-chlorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H18ClNS
|
1
|
| 1 |
EC50 = 5.3 nM
|
|
|
|
CP0540181
|
5-(3,4-difluorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H17F2NS
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0088155
|
9-Fluoro-2,2,4-trimethyl-5-[1-thiophen-3-yl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C24H20FNOS
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
|
CP0467640
|
6-(3-chlorophenyl)-4-methyl-4-phenyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C21H16ClNOS
|
1
|
| 1 |
EC50 = 5.7 nM
|
|
|
|
CP0498355
|
6-(5-bromopyridin-3-yl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C15H13BrN2OS
|
1
|
| 1 |
EC50 = 5.7 nM
|
|
|
|
CP0276435
|
4-((2-chlorobenzyl)(1-(1-methyl-1H-pyrazol-5-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C20H18Cl2N4
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0230196
|
(S)-2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)benzonitrile
Show/Hide
|
C19H25ClN6
|
1
|
| 1 |
EC50 = 6.8 nM
|
|
|
|
CP0503072
|
6-(3-methoxyphenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C17H17NO2S
|
1
|
| 1 |
EC50 = 7.2 nM
|
|
|
|
CP0528667
|
6-(3-chlorophenyl)-4,4-diethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C18H18ClNOS
|
1
|
| 1 |
EC50 = 7.2 nM
|
|
|
|
CP0478210
|
4-propyl-5-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)thiophene-2-carbonitrile
Show/Hide
|
C21H22N2S2
|
1
|
| 1 |
EC50 = 7.7 nM
|
|
|
|
CP0185600
|
9-Fluoro-5-[1-(2-methoxy-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C27H24FNO2
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0193172
|
7-Fluoro-5-[1-(4-fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C26H21F2NO
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0166214
|
(S)-methyl 3-((3-chloro-4-cyanophenyl)(2-(trifluoromethyl)benzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
|
C21H19ClF3N3O2
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0430329
|
3-(2,4-Dimethyl-4-phenyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
|
C23H19FN2O
|
2
|
| 1 |
EC50 = 8.2 nM
|
|
|
| 2 |
IC50 = 24.7 nM
|
|
|
|
CP0063848
|
7-Fluoro-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C27H24FNO
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0038907
|
(S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C20H19ClF3N3
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0448428
|
4-(2,2,4,4-Tetramethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H18N2OS
|
1
|
| 1 |
EC50 = 9.2 nM
|
|
|
|
CP0226070
|
2-chloro-4-(isobutyl(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)benzonitrile
Show/Hide
|
C18H25ClN6
|
1
|
| 1 |
EC50 = 9.5 nM
|
|
|
|
CP0406469
|
5-(3-chlorophenyl)spiro[1H-indole-3,1'-cyclopentane]-2-thione
Show/Hide
|
C18H16ClNS
|
1
|
| 1 |
EC50 = 9.8 nM
|
|
|
|
CP0175610
|
9-Chloro-2,2,4,5-tetramethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C20H20ClNO
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0151287
|
(S)-2-chloro-4-((1-(isobutylsulfonyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C23H25ClF3N3O2S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0430719
|
5-(3,3-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C17H16N2O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0107815
|
(4S,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
|
C25H22ClNO2
|
1
|
| 1 |
EC50 = 10.9 nM
|
|
|
|
CP0438550
|
3-Fluoro-5-(2,2,4,4-tetramethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
|
C19H19FN2O
|
2
|
| 1 |
EC50 = 10.9 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0162846
|
7-Fluoro-2,2,4-trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C26H22FNO
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0167501
|
2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)benzonitrile
Show/Hide
|
C19H25ClN6
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0135950
|
(S)-2-chloro-4-((1-(methylsulfonyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C20H19ClF3N3O2S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0470439
|
6-(3,4-difluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H13F2NOS
|
1
|
| 1 |
EC50 = 11.4 nM
|
|
|
|
CP0539025
|
6-(2-fluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H14FNOS
|
1
|
| 1 |
EC50 = 11.6 nM
|
|
|
|
CP0185145
|
9-Fluoro-2,2,4-trimethyl-5-[1-(3-methyl-pyridin-2-yl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C26H23FN2O
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0108762
|
4-((2-chlorobenzyl)(1-(5-methyl-1,3,4-oxadiazol-2-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H16Cl2N4O
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0106426
|
(4S,5S)-5-(3-Fluoro-phenyl)-2,2,4-trimethyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
|
C25H22FNO2
|
1
|
| 1 |
EC50 = 14.8 nM
|
|
|
|
CP0505861
|
2-fluoro-4-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)benzonitrile
Show/Hide
|
C20H17FN2S
|
1
|
| 1 |
EC50 = 14.8 nM
|
|
|
|
CP0101021
|
5-[1-(2-Ethyl-phenyl)-meth-(Z)-ylidene]-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C28H26FNO
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0286195
|
7-Fluoro-5-[1-(3-fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C26H21F2NO
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0148253
|
2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
|
C26H23NO2
|
1
|
| 1 |
EC50 = 18.3 nM
|
|
|
|
CP0182597
|
9-Fluoro-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C27H24FNO
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0491334
|
5-(1-hydroxy-3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0100985
|
9-Fluoro-5-[1-furan-2-yl-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C24H20FNO2
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0148252
|
(4R,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
|
C25H22ClNO2
|
1
|
| 1 |
EC50 = 22.6 nM
|
|
|
|
CP0463685
|
2-Fluoro-5-(2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
|
C18H17FN2O
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
IC50 = 166 nM
|
|
|
|
CP0114693
|
(4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
|
C25H23NO2
|
1
|
| 1 |
EC50 = 23.5 nM
|
|
|
|
CP0548453
|
4-butyl-5-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)thiophene-2-carbonitrile
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C22H24N2S2
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1
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| 1 |
EC50 = 23.5 nM
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CP0151326
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(S)-2-chloro-4-((1-propionylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
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C22H21ClF3N3O
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1
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| 1 |
EC50 = 24 nM
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CP0184486
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5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
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C26H22FNO2
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1
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| 1 |
EC50 = 25 nM
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CP0214889
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(S)-2-chloro-4-((2-methylbenzyl)(1-(methylsulfonyl)pyrrolidin-3-yl)amino)benzonitrile
Show/Hide
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C20H22ClN3O2S
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1
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| 1 |
EC50 = 25 nM
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CP0107672
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(4R,5S)-5-(3-Fluoro-phenyl)-2,2,4-trimethyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
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C25H22FNO2
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1
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| 1 |
EC50 = 26 nM
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CP0112566
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2-[(Z)-(9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinolin-5-ylidene)methyl]-N,N-dimethylaniline
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C28H27FN2O
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1
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| 1 |
EC50 = 26 nM
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CP0454731
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6-(3,5-dichlorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
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C16H13Cl2NOS
|
1
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| 1 |
EC50 = 26.5 nM
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CP0172383
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5-(3-Chloro-phenyl)-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C25H21ClFNO
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1
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| 1 |
EC50 = 27 nM
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CP0291645
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(5S)-5-[(1S)-cyclohex-2-en-1-yl]-7,9-difluoro-2,2,4-trimethyl-1,5-dihydrochromeno[3,4-f]quinoline
Show/Hide
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C25H25F2NO
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1
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| 1 |
EC50 = 27 nM
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CP0104425
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2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C27H25NO
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1
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| 1 |
EC50 = 28 nM
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CP0200504
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9-Fluoro-2,2,4-trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C26H22FNO
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1
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| 1 |
EC50 = 28 nM
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CP0530701
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5-(3-chlorophenyl)spiro[1H-indole-3,1'-cyclobutane]-2-thione
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C17H14ClNS
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1
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| 1 |
EC50 = 28.7 nM
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CP0257394
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9-Fluoro-5-[1-(2-fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C26H21F2NO
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1
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| 1 |
EC50 = 29 nM
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CP0358321
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(R)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
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C20H19ClF3N3
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1
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| 1 |
EC50 = 30 nM
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CP0442606
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5-(2-oxo-2,3-dihydro-1H-spiro[4,1-benzoxazepine-5,1'-cyclohexan]-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C19H19N3O2
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1
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| 1 |
EC50 = 30.5 nM
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CP0185464
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5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C25H22ClNO
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1
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| 1 |
EC50 = 32 nM
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CP0454503
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6-(3-Chloro-phenyl)-2,2,4,4-tetramethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine
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C18H20ClNO
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2
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| 1 |
EC50 = 32 nM
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| 2 |
IC50 = 10 nM
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CP0469556
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6-(3-Chloro-4-fluoro-phenyl)-2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine
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C17H17ClFNO
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2
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| 1 |
EC50 = 32 nM
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| 2 |
IC50 = 212.5 nM
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CP0506148
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(5S)-7,9-difluoro-2,2,4-trimethyl-5-[(1R)-3-methylcyclohex-2-en-1-yl]-1,5-dihydrochromeno[3,4-f]quinoline
Show/Hide
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C26H27F2NO
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1
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| 1 |
EC50 = 33 nM
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CP0164908
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(4R,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
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C25H23NO2
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1
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| 1 |
EC50 = 35 nM
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CP0108648
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4-((2-chlorobenzyl)(1-(1-isopropyl-1H-tetrazol-5-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
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C20H20Cl2N6
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1
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| 1 |
EC50 = 35 nM
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CP0192248
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(S)-4-((1-acetylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)-2-chlorobenzonitrile
Show/Hide
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C21H19ClF3N3O
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1
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| 1 |
EC50 = 35 nM
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CP0208355
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(S)-2-chloro-4-((2,3-difluorobenzyl)(1-methyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
Show/Hide
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C19H16ClF2N3O
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1
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| 1 |
EC50 = 35 nM
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CP0441465
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7-(3,5-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(3H)-thione
Show/Hide
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C17H15F2NOS
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1
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| 1 |
EC50 = 35.8 nM
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CP0096192
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(S)-2-chloro-4-((2-fluorobenzyl)(1-(methylsulfonyl)pyrrolidin-3-yl)amino)benzonitrile
Show/Hide
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C19H19ClFN3O2S
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1
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| 1 |
EC50 = 36 nM
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CP0147609
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(4S,5S)-2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
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C26H22F3NO2
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1
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| 1 |
EC50 = 37 nM
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CP0442607
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5-(1,5-dimethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C21H19N3O2S
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1
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| 1 |
EC50 = 37.5 nM
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CP0185170
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9-Fluoro-2,2,4-trimethyl-5-[1-(2-methylsulfanyl-phenyl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C27H24FNOS
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1
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| 1 |
EC50 = 41 nM
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CP0298735
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(S)-methyl 3-((3-chloro-4-cyanophenyl)(5-fluoro-2-methylbenzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
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C21H21ClFN3O2
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1
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| 1 |
EC50 = 41 nM
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CP0458821
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5-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)benzene-1,3-dicarbonitrile
Show/Hide
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C18H13N3OS
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1
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| 1 |
EC50 = 42 nM
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CP0361542
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9-Fluoro-2,2,4-trimethyl-5-[1-pyridin-2-yl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C25H21FN2O
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1
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| 1 |
EC50 = 44 nM
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CP0540936
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3-chloro-5-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)benzonitrile
Show/Hide
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C17H13ClN2OS
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1
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| 1 |
EC50 = 44.9 nM
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CP0201054
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2-[9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-(5Z)-ylidenemethyl]-benzaldehyde
Show/Hide
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C27H22FNO2
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1
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| 1 |
EC50 = 48 nM
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CP0471225
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6-(3-chloro-4-fluorophenyl)-1-cyclopentyl-1,3-dihydro-2H-benzimidazole-2-thione
Show/Hide
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C18H16ClFN2S
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1
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| 1 |
EC50 = 49.3 nM
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CP0438544
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6-(2-chlorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
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C16H14ClNOS
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1
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| 1 |
EC50 = 49.8 nM
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CP0301589
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5-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C26H21BrFNO
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1
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| 1 |
EC50 = 50 nM
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CP0301665
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5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C26H22FNO
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1
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| 1 |
EC50 = 51 nM
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CP0453719
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9-Fluoro-5-[1-(2-isopropyl-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C29H28FNO
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1
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| 1 |
EC50 = 54 nM
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CP0095680
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9-Fluoro-2,2,4-trimethyl-5-[1-(2-propyl-phenyl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
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C29H28FNO
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1
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| 1 |
EC50 = 59 nM
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CP0514236
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5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-dihydro-1'H-indole)]-5-yl]-1H-2-pyrrolecarbonitrile
Show/Hide
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C18H17N3O
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2
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| 1 |
EC50 = 60 nM
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| 2 |
IC50 > 3000 nM
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CP0503518
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4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
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C15H12N2O2S
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1
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| 1 |
EC50 = 61.1 nM
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CP0424334
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1-cyclopentyl-6-(3,4-difluorophenyl)-1,3-dihydro-2H-benzimidazole-2-thione
Show/Hide
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C18H16F2N2S
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1
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| 1 |
EC50 = 62.5 nM
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CP0097577
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(4R,5S)-2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one
Show/Hide
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C26H22F3NO2
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1
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| 1 |
EC50 = 63 nM
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CP0201477
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(S)-2-chloro-4-((1-methyl-5-oxopyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
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C20H17ClF3N3O
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1
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| 1 |
EC50 = 70 nM
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CP0478191
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5-(3-phenylphenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
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C25H23NS
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1
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| 1 |
EC50 = 71.4 nM
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CP0144191
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(S)-2-chloro-4-((5-fluoro-2-methylbenzyl)(1-propionylpyrrolidin-3-yl)amino)benzonitrile
Show/Hide
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C22H23ClFN3O
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1
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| 1 |
EC50 = 75 nM
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CP0527369
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6-(3-chloro-4-fluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
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C16H13ClFNOS
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1
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| 1 |
EC50 = 79.5 nM
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CP0477151
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3-(8-bromo-4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)-5-fluorobenzonitrile
Show/Hide
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C17H12BrFN2OS
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1
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| 1 |
EC50 = 80.1 nM
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CP0341518
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7-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene-9-carbonitrile
Show/Hide
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C20H17FN2O
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2
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| 1 |
EC50 = 86 nM
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| 2 |
IC50 = 149 nM
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CP0383397
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4-benzyl-6-(3-chlorophenyl)-4-methyl-1H-3,1-benzoxazine-2-thione
Show/Hide
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C22H18ClNOS
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1
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| 1 |
EC50 = 88.5 nM
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CP0496251
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3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
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C17H13FN2O2
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2
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| 1 |
EC50 = 90 nM
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| 2 |
IC50 = 90 nM
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CP0298531
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(5S)-5-[(1S)-2,3-dimethylcyclohex-2-en-1-yl]-7,9-difluoro-2,2,4-trimethyl-1,5-dihydrochromeno[3,4-f]quinoline
Show/Hide
|
C27H29F2NO
|
1
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| 1 |
EC50 = 96 nM
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CP0305346
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2-[9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-(5Z)-ylidenemethyl]-benzonitrile
Show/Hide
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C27H21FN2O
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1
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| 1 |
EC50 = 97 nM
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CP0529596
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5-((5S)-5-methyl-2-oxo-5-(thiophen-3-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H15N3O2S
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1
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| 1 |
EC50 = 110 nM
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CP0497714
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5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-imidazole-2-carbonitrile
Show/Hide
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C15H14N4O2
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2
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| 1 |
EC50 = 130 nM
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| 2 |
IC50 > 3000 nM
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CP0201476
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(S)-2-chloro-4-((2-fluorobenzyl)(1-methyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
Show/Hide
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C19H17ClFN3O
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1
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| 1 |
EC50 = 135 nM
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CP0180141
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(S)-methyl 3-((3-chloro-4-cyanophenyl)(2,3-difluorobenzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
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C20H18ClF2N3O2
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1
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| 1 |
EC50 = 137 nM
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CP0386408
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1-methyl-5-(5-methyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C16H15N3O2
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1
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| 1 |
EC50 = 137.7 nM
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CP0102801
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4-((2-(trifluoromethyl)benzyl)(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)-2-chlorobenzonitrile
Show/Hide
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C22H22ClF3N6
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1
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| 1 |
EC50 = 139 nM
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CP0247673
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4-((2-chlorobenzyl)(3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)butyl)amino)-2-chlorobenzonitrile
Show/Hide
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C22H23Cl2N5
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1
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| 1 |
EC50 = 157 nM
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CP0193258
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9-Fluoro-2,2,4-trimethyl-5-[1-(2-trifluoromethyl-phenyl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C27H21F4NO
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1
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| 1 |
EC50 = 161 nM
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CP0135955
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(S)-2-chloro-4-((2,5-dichlorobenzyl)(1-propionylpyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C21H20Cl3N3O
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1
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| 1 |
EC50 = 163 nM
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CP0038902
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(S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluorobenzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
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C20H19ClFN3O2
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1
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| 1 |
EC50 = 165 nM
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CP0082132
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9-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H18ClNO
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1
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| 1 |
EC50 = 171 nM
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CP0096194
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2-chloro-4-((5-fluoro-2-methylbenzyl)((S)-1-((S)-2-hydroxypropanoyl)pyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C22H23ClFN3O2
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1
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| 1 |
EC50 = 183 nM
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CP0137848
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9-Fluoro-2,2,4-trimethyl-5-[1-(2-trifluoromethoxy-phenyl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C27H21F4NO2
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1
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| 1 |
EC50 = 190 nM
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CP0226069
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4-((2-chlorobenzyl)((1-methyl-1H-tetrazol-5-yl)methyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C17H14Cl2N6
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1
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| 1 |
EC50 = 197 nM
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CP0555217
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3-(4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)-5-methylbenzonitrile
Show/Hide
|
C18H16N2OS
|
1
|
| 1 |
EC50 = 200 nM
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CP0538915
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5-(3-chlorophenyl)-3,3-diethyl-1H-indole-2-thione
Show/Hide
|
C18H18ClNS
|
1
|
| 1 |
EC50 = 200 nM
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CP0144196
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2-chloro-4-(((S)-1-((S)-2-hydroxypropanoyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C22H21ClF3N3O2
|
1
|
| 1 |
EC50 = 208 nM
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CP0192247
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(S)-isopropyl 3-((3-chloro-4-cyanophenyl)(5-fluoro-2-methylbenzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
|
C23H25ClFN3O2
|
1
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| 1 |
EC50 = 233 nM
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CP0349897
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7,9-Difluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H17F2NO
|
2
|
| 1 |
EC50 = 244 nM
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| 2 |
IC50 = 86 nM
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CP0301622
|
4-(2,2,4-Trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H16N2S
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2
|
| 1 |
EC50 = 245 nM
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| 2 |
IC50 = 106 nM
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CP0484794
|
5-(5-methyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C15H13N3O2
|
1
|
| 1 |
EC50 = 245.8 nM
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CP0295910
|
2,2,4-Trimethyl-9-nitro-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H18N2O3
|
2
|
| 1 |
EC50 = 257 nM
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| 2 |
IC50 = 152 nM
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|
|
CP0454952
|
3-[3-(1-ethylpropyl)-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl]-5-fluorobenzonitrile
Show/Hide
|
C19H18FN3S
|
2
|
| 1 |
EC50 = 269.8 nM
|
|
|
| 2 |
IC50 = 3.6 nM
|
|
|
|
CP0073410
|
4-((2-chlorobenzyl)(1-(3-methylisoxazol-5-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C20H17Cl2N3O
|
1
|
| 1 |
EC50 = 272 nM
|
|
|
|
CP0144205
|
(S)-2-chloro-4-((1-isobutyrylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C23H23ClF3N3O
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0402926
|
6-(3-fluorophenyl)-4-methyl-1,4-dihydro-3,1-benzoxazine-2-thione
Show/Hide
|
C15H12FNOS
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0477953
|
1-methyl-5-(2-oxospiro[1H-indole-3,1'-cyclopentane]-5-yl)pyrrole-2-carbonitrile
Show/Hide
|
C18H17N3O
|
3
|
| 1 |
EC50 = 300 nM
|
|
|
| 2 |
IC50 = 8.1 nM
|
|
|
| 3 |
IC50 = 30 nM
|
|
|
|
CP0180140
|
2-chloro-4-((2,5-dichlorobenzyl)((S)-1-((S)-2-hydroxypropanoyl)pyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C21H20Cl3N3O2
|
1
|
| 1 |
EC50 = 341 nM
|
|
|
|
CP0099192
|
9-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H18FNO
|
2
|
| 1 |
EC50 = 351 nM
|
|
|
| 2 |
IC50 = 335 nM
|
|
|
|
CP0268769
|
(S)-ethyl 3-((3-chloro-4-cyanophenyl)(5-fluoro-2-methylbenzyl)amino)pyrrolidine-1-carboxylate
Show/Hide
|
C22H23ClFN3O2
|
1
|
| 1 |
EC50 = 364 nM
|
|
|
|
CP0073408
|
4-((2-chlorobenzyl)(1-(2-methylthiazol-4-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C20H17Cl2N3S
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0135953
|
(S)-2-chloro-4-((1-pivaloylpyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C24H25ClF3N3O
|
1
|
| 1 |
EC50 = 400 nM
|
|
|
|
CP0196605
|
4-Methyl-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C18H18N2S
|
2
|
| 1 |
EC50 = 500 nM
|
|
|
| 2 |
IC50 = 123 nM
|
|
|
|
CP0493508
|
6-(3-Chloro-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Show/Hide
|
C16H13ClFNO2
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0134207
|
9-Bromo-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H18BrNO
|
2
|
| 1 |
EC50 = 552 nM
|
|
|
| 2 |
IC50 = 485 nM
|
|
|
|
CP0082136
|
3,5-Dimethyl-4-(2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C19H20N2S
|
2
|
| 1 |
EC50 = 580 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0259640
|
4-((2-chlorobenzyl)(1-(1-methyl-1H-1,2,3-triazol-4-yl)ethyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H17Cl2N5
|
1
|
| 1 |
EC50 = 606 nM
|
|
|
|
CP0336153
|
(S)-2-chloro-4-((2,4-difluorobenzyl)(1-methyl-5-oxopyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C19H16ClF2N3O
|
1
|
| 1 |
EC50 = 625 nM
|
|
|
|
CP0082134
|
4-Bromo-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H15BrN2S
|
2
|
| 1 |
EC50 = 700 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0152611
|
4-(((3S)-1-sec-butyl-5-oxopyrrolidin-3-yl)(2-methylbenzyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C23H26ClN3O
|
1
|
| 1 |
EC50 = 750 nM
|
|
|
|
CP0038906
|
(S)-4-(benzyl(1-(methylsulfonyl)pyrrolidin-3-yl)amino)-2-chlorobenzonitrile
Show/Hide
|
C19H20ClN3O2S
|
1
|
| 1 |
EC50 = 843 nM
|
|
|
|
CP0448890
|
8-bromo-6-(4-chloro-3-fluorophenyl)-4,4-dimethyl-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C16H12BrClFNOS
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0509942
|
4,4-dibenzyl-6-(3-chlorophenyl)-1H-3,1-benzoxazine-2-thione
Show/Hide
|
C28H22ClNOS
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0531396
|
3-fluoro-5-(8-fluoro-4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)benzonitrile
Show/Hide
|
C17H12F2N2OS
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0194317
|
2,2,4-Trimethyl-6-(5-nitro-thiophen-2-yl)-1,2-dihydro-quinoline
Show/Hide
|
C16H16N2O2S
|
2
|
| 1 |
EC50 = 1024 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0144199
|
(S)-2-chloro-4-((2-cyanobenzyl)(1-(methylsulfonyl)pyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C20H19ClN4O2S
|
1
|
| 1 |
EC50 = 1130 nM
|
|
|
|
CP0539010
|
3-benzyl-5-(3-chlorophenyl)-3-methyl-1H-indole-2-thione
Show/Hide
|
C22H18ClNS
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0322350
|
2-Chloro-4-[[(3S)-1-methyl-5-oxo-3-pyrrolidinyl](phenylmethyl)amino]benzonitrile
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
EC50 = 1265 nM
|
|
|
|
CP0040461
|
5-Methyl-4-(2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C18H18N2S
|
2
|
| 1 |
EC50 = 1400 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0322347
|
(S)-2-chloro-4-((2-methylbenzyl)(5-oxo-1-propylpyrrolidin-3-yl)amino)benzonitrile
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
EC50 = 1415 nM
|
|
|
|
CP0167504
|
4-((2-chlorobenzyl)(1-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)-2-methylpropyl)amino)-2-chlorobenzonitrile
Show/Hide
|
C22H23Cl2N5
|
1
|
| 1 |
EC50 = 1665 nM
|
|
|
|
CP0311285
|
5-(2,2,4-Trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H16N2S
|
2
|
| 1 |
EC50 = 1800 nM
|
|
|
| 2 |
IC50 = 80 nM
|
|
|
|
CP0540273
|
5-(4-chlorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-thione
Show/Hide
|
C19H18ClNS
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0038093
|
3-Fluoro-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-benzonitrile
Show/Hide
|
C19H17FN2
|
2
|
| 1 |
EC50 = 2200 nM
|
|
|
| 2 |
IC50 = 37 nM
|
|
|
|
CP0281562
|
(S)-2-chloro-4-((1-(propylsulfonyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C22H23ClF3N3O2S
|
1
|
| 1 |
EC50 = 2630 nM
|
|
|
|
CP0254309
|
6-(5-Chloro-thiophen-2-yl)-2,2,4-trimethyl-1,2-dihydro-quinoline
Show/Hide
|
C16H16ClNS
|
2
|
| 1 |
EC50 = 2650 nM
|
|
|
| 2 |
IC50 = 151 nM
|
|
|
|
CP0525665
|
5-(7-fluoro-2-oxospiro[1H-indole-3,1'-cyclopentane]-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C18H16FN3O
|
3
|
| 1 |
EC50 = 3000 nM
|
|
|
| 2 |
IC50 = 3.2 nM
|
|
|
| 3 |
IC50 = 14.7 nM
|
|
|
|
CP0144318
|
(S)-2-chloro-4-((1-(ethylsulfonyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C21H21ClF3N3O2S
|
1
|
| 1 |
EC50 = 3160 nM
|
|
|
|
CP0110334
|
6-(4-Bromo-thiophen-2-yl)-2,2,4-trimethyl-1,2-dihydro-quinoline
Show/Hide
|
C16H16BrNS
|
2
|
| 1 |
EC50 = 3500 nM
|
|
|
| 2 |
IC50 = 190 nM
|
|
|
|
CP0391474
|
3-(2-tert-Butyl-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
|
C21H23FN2O
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 126.6 nM
|
|
|
| 3 |
IC50 = 3042 nM
|
|
|
|
CP0395437
|
3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
|
C20H21FN2O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0422205
|
4-(1-Acetyl-4,4-dimethyl-2-trifluoromethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C18H15F3N2O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 2087 nM
|
|
|
|
CP0422206
|
2-(4-Amino-3'-chloro-biphenyl-3-yl)-propan-2-ol
Show/Hide
|
C15H16ClNO
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 103 nM
|
|
|
| 3 |
IC50 = 301 nM
|
|
|
|
CP0422212
|
6-(3-Cyano-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine-2-carboxylic acid ethyl ester
Show/Hide
|
C20H19FN2O3
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 158.8 nM
|
|
|
| 3 |
IC50 = 1793 nM
|
|
|
|
CP0436574
|
3-(4,4-Dimethyl-2-thiophen-2-yl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
|
C21H17FN2OS
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 51.2 nM
|
|
|
| 3 |
IC50 = 1682 nM
|
|
|
|
CP0466861
|
3-(4,4-Dimethyl-2-phenyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
|
C23H19FN2O
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 92.6 nM
|
|
|
| 3 |
IC50 = 2060 nM
|
|
|
|
CP0475583
|
6-(5-Cyano-thiophen-3-yl)-4,4-dimethyl-2-trifluoromethyl-4H-benzo[d][1,3]oxazine-1-carboxylic acid methyl ester
Show/Hide
|
C18H15F3N2O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0383515
|
3-Bromo-5-(4,4-dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
|
C17H13BrN2OS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0395192
|
3-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-methoxy-benzonitrile
Show/Hide
|
C18H16N2O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0402851
|
6-(3-Bromo-phenyl)-1,4,4-trimethyl-1,4-dihydro-benzo[d][1,3]oxazine-2-thione
Show/Hide
|
C17H16BrNOS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 114 nM
|
|
|
|
CP0460170
|
3-(1-Ethyl-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
Show/Hide
|
C19H17FN2OS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0460726
|
6-(3-Bromo-5-methyl-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazine-2-thione
Show/Hide
|
C17H16BrNOS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0460845
|
6-(3-Bromo-5-fluoro-phenyl)-1,4,4-trimethyl-1,4-dihydro-benzo[d][1,3]oxazine-2-thione
Show/Hide
|
C17H15BrFNOS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0463722
|
6-(3-Bromo-5-trifluoromethoxy-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazine-2-thione
Show/Hide
|
C17H13BrF3NO2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0466440
|
3-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-trifluoromethoxy-benzonitrile
Show/Hide
|
C18H13F3N2O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0544769
|
4-(8-bromo-4,4-dimethyl-2-sulfanylidene-1H-3,1-benzoxazin-6-yl)-2-fluorobenzonitrile
Show/Hide
|
C17H12BrFN2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0229691
|
(S)-2-chloro-4-((1-(isopropylsulfonyl)pyrrolidin-3-yl)(2-(trifluoromethyl)benzyl)amino)benzonitrile
Show/Hide
|
C22H23ClF3N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0050852
|
2-[(1S)-5-{3-[2-propyl-4-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Show/Hide
|
C30H35NO4S
|
1
|
| 1 |
EC50 > 10 nM
|
|
|
|
CP0145989
|
2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Show/Hide
|
C27H29NO4S
|
1
|
| 1 |
EC50 > 10 nM
|
|
|
|
CP0717529
|
[(1S)-5-{3-[4-(6,7-dihydro-5H-pyrano[2,3-d]1,3thiazol-2-yl)-2-propylphenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Show/Hide
|
C29H35NO5S
|
1
|
| 1 |
EC50 > 10 nM
|
|
|
|
CP0082128
|
2,2,4,9-Tetramethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C20H21NO
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0082129
|
7-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H18FNO
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 368 nM
|
|
|
|
CP0082133
|
2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H19NO
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 138 nM
|
|
|
|
CP0106007
|
9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C20H21NO2
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 187 nM
|
|
|
|
CP0288560
|
8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C20H21NO2
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 514 nM
|
|
|
|
CP0382372
|
5'-(5-nitro-1H-2-pyrrolyl)spiro[cyclohexane-1,3'-(2',3'-dihydro-1'H-indole)]-2'-one
Show/Hide
|
C17H17N3O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 36 nM
|
|
|
|
CP0404868
|
3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-5'-yl)benzonitrile
Show/Hide
|
C20H18N2O
|
5
|
| 1 |
EC50 ~ 1000 nM
|
|
|
| 2 |
IC50 = 6.6 nM
|
|
|
| 3 |
IC50 = 14.7 nM
|
|
|
| 4 |
IC50 = 15 nM
|
|
|
| 5 |
IC50 = 25 nM
|
|
|
|
CP0408419
|
3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
|
C17H14N2O2
|
3
|
| 1 |
EC50 ~ 1000 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
| 3 |
IC50 = 17 nM
|
|
|
|
CP0422143
|
5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C15H12N2O2S
|
2
|
| 1 |
EC50 ~ 1000 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
|
CP0448615
|
4,4-Dimethyl-6-[5-(2,2,2-trifluoro-acetyl)-1H-pyrrol-2-yl]-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Show/Hide
|
C16H13F3N2O3
|
2
|
| 1 |
EC50 ~ 1000 nM
|
|
|
| 2 |
IC50 > 3000 nM
|
|
|
|
CP0448621
|
4,4-Dimethyl-6-(5-nitro-1H-pyrrol-2-yl)-1,4-dihydro-benzo[d][1,3]oxazin-2-one
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C14H13N3O4
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2
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| 1 |
EC50 ~ 1000 nM
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| 2 |
IC50 = 180 nM
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CP0463025
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4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C16H15N3O2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 41 nM
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CP0483567
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2-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1H-pyrrole-3-carbonitrile
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C15H13N3O2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 3000 nM
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CP0496993
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5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1H-pyrrole-2-carbaldehyde
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C15H14N2O3
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2
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| 1 |
EC50 ~ 1000 nM
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| 2 |
IC50 > 3000 nM
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CP0497277
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4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1H-pyrrole-2-carbonitrile
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C15H13N3O2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 ~ 2000 nM
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CP0499484
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2-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-1-methyl-1H-pyrrole-3-carbonitrile
Show/Hide
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C16H15N3O2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 ~ 3000 nM
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CP0509602
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5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-oxazole-2-carbonitrile
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C14H11N3O3
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 ~ 3000 nM
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CP0406467
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5'-(3-chlorophenyl)-1'-methylspiro[cyclohexane-1,3'-indole]-2'-thione
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C20H20ClNS
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1
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| 1 |
EC50 > 3000 nM
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CP0529885
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5-(3-chlorophenyl)-3-methyl-1H-indole-2-thiol
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C15H12ClNS
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1
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| 1 |
EC50 > 3000 nM
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CP0373890
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5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-furan-2-carbonitrile
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C15H12N2O3
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2
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| 1 |
EC50 ~ 3000 nM
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| 2 |
IC50 = 65 nM
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CP0404784
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4,4-Dimethyl-6-(1H-pyrrol-2-yl)-1,4-dihydro-benzo[d][1,3]oxazin-2-one
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C14H14N2O2
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 ~ 3000 nM
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CP0421199
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5-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C18H18N4O
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3
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 5.6 nM
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| 3 |
IC50 = 26.2 nM
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CP0428499
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5-[3-(1-ethylpropyl)-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]-1-methyl-1H-pyrrole-2-carbonitrile
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C18H20N4O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 11.7 nM
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CP0440101
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5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C17H16N4O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 10.9 nM
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CP0388448
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5-(1-hydroxy-3-methyl-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C16H16N2O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 18 nM
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CP0401275
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1-methyl-5-(1-oxo-2,3-dihydro-1H-inden-5-yl)-1H-pyrrole-2-carbonitrile
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C15H12N2O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 34 nM
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CP0494739
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5-(1-hydroxy-3,3-dimethyl-1-(prop-2-ynyl)-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C20H20N2O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 3 nM
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CP0506559
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5-(1-hydroxy-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C15H14N2O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 10 nM
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CP0914162
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5-(1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C15H13N3O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 132 nM
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CP0914163
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5-(1-(hydroxyimino)-3-methyl-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C16H15N3O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 65 nM
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CP0915583
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5-(1-(hydroxyimino)-3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C17H17N3O
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
IC50 = 14 nM
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CP0035186
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(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
Show/Hide
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C29H35NO2
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9
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| 1 |
IC50 = 0.045 nM
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| 2 |
IC50 = 0.054 nM
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| 3 |
IC50 = 0.073 nM
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| 4 |
IC50 = 0.1 nM
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| 5 |
IC50 = 0.13 nM
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| 6 |
IC50 = 0.2 nM
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| 7 |
IC50 = 0.6 nM
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| 8 |
IC50 = 1.4 nM
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| 9 |
IC50 = 3.3 nM
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CP0422761
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17beta-Hydroxy-11beta-[4-(6-hydroxy-N-methylhexylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C34H45NO3
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1
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| 1 |
IC50 = 0.06 nM
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CP0194207
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(8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phenyl)-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one
Show/Hide
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C28H32O3
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1
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| 1 |
IC50 = 0.095 nM
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CP0422906
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17beta-Hydroxy-11beta-[4-(3-hydroxy-N-methypropylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C31H39NO3
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1
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| 1 |
IC50 = 0.12 nM
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CP0386186
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17beta-Hydroxy-11beta-[4-(5-formyl-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C34H43NO3
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1
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| 1 |
IC50 = 0.15 nM
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CP0382009
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17beta-Hydroxy-11beta-[4-(2-methoxycarbonyl-N-methylethylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C32H39NO4
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1
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| 1 |
IC50 = 0.16 nM
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CP0386187
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17beta-Hydroxy-11beta-{4-[methyl-3-(4-chlorphenyl)-thioureido]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C35H37ClN2O2S
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1
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| 1 |
IC50 = 0.16 nM
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CP0377452
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17beta-Hydroxy-11beta-[4-(1-methyl-9,12-dioxo-1-aza-8,13-dioxa-tetradecyl)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C39H51NO6
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1
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| 1 |
IC50 = 0.17 nM
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CP0381160
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17beta-Hydroxy-11beta-[4-(methylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C28H33NO2
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1
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| 1 |
IC50 = 0.17 nM
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CP0462313
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17beta-Hydroxy-11beta-{4-[5-(1,3-dioxol-2-yl)-N-methylpentylamino]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C36H47NO4
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1
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| 1 |
IC50 = 0.17 nM
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CP0463815
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17beta-Hydroxy-11beta-[4-(12-hydroxy-1-methyl-9,12-dioxo-1-aza-8-oxa-dodecyl)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C38H49NO6
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1
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| 1 |
IC50 = 0.25 nM
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CP0382012
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17beta-Hydroxy-11beta-[4-(N-methylpropylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C31H39NO2
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1
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| 1 |
IC50 = 0.27 nM
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CP0463845
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17beta-Hydroxy-11beta-{4-[methyl-3-(4-chlorphenyl)-ureido]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C35H37ClN2O3
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1
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| 1 |
IC50 = 0.27 nM
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CP0481366
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17beta-Hydroxy-11beta-[4-(7-carboxy-N-methylheptylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C36H47NO4
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1
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| 1 |
IC50 = 0.27 nM
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CP0436544
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(8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4-fluoro-phenylethynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H34FNO3
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1
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| 1 |
IC50 = 0.27 nM
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CP0404923
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(1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-hydroxy-1-isopropenyl-12a-methyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
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C29H37NO3
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1
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| 1 |
IC50 = 0.3 nM
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CP0845015
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Asoprinsil
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C28H35NO4
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1
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| 1 |
IC50 = 0.3 nM
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CP0393072
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(3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-ethyl-15'-methyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C31H35NO3
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1
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| 1 |
IC50 = 0.34 nM
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CP0463814
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17beta-Hydroxy-11beta-[4-(5-ethoxycarbonyl-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C35H45NO4
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1
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| 1 |
IC50 = 0.4 nM
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CP0422762
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17beta-Hydroxy-11beta-[4-(5-carboxy-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C34H43NO4
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1
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| 1 |
IC50 = 0.44 nM
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CP0434939
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17beta-Hydroxy-11beta-{4-[1-methyl-4-oxo-5-(4-carbamoyl-3-hydroxyphenyl)-1,5-diazapentyl]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C38H43N3O5
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1
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| 1 |
IC50 = 0.44 nM
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CP0462314
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17beta-Hydroxy-11beta-{4-[1-methyl-6-(4-carbamoyl-3-hydroxyphenyl)-1-aza-5-oxa-hexyl]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C39H46N2O5
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1
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| 1 |
IC50 = 0.46 nM
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CP0463817
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17beta-Hydroxy-11beta-[4-(10-carboxy-N-methyldecylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C39H53NO4
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1
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| 1 |
IC50 = 0.46 nM
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CP0502996
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17beta-Hydroxy-11beta-[4-(7-methoxycarbonyl-N-methylheptylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C37H49NO4
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1
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| 1 |
IC50 = 0.47 nM
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CP0459684
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17beta-Hydroxy-11beta-[4-(5-carbamoyl-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C34H44N2O3
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1
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| 1 |
IC50 = 0.55 nM
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CP0551874
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(3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15'-dimethyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C30H33NO3
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1
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| 1 |
IC50 = 0.59 nM
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CP0458933
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(8S,11R,13S,14R,17S)-17-(4-chloro-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H34ClNO3
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1
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| 1 |
IC50 = 0.61 nM
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CP0504936
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(3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phenyl]-5,15'-dimethyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C30H36N2O2
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1
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| 1 |
IC50 = 0.63 nM
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CP0434964
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17beta-Hydroxy-11beta-[4-(10-methoxycarbonyl-N-methyldecylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C40H55NO4
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1
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| 1 |
IC50 = 0.63 nM
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CP0422903
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17beta-Hydroxy-11beta-[4-(N-methylhexylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C34H45NO2
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1
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| 1 |
IC50 = 0.66 nM
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CP0529423
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17beta-Hydroxy-11beta-[4-(1-oxo-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C34H43NO3
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1
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| 1 |
IC50 = 0.69 nM
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CP0467670
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17beta-Hydroxy-11beta-[4-(1-methyl-3-butylthioureido)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C33H42N2O2S
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1
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| 1 |
IC50 = 0.73 nM
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CP0465249
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-(4-trifluoromethyl-phenylethynyl)-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C34H34F3NO3
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1
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| 1 |
IC50 = 0.75 nM
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CP0493457
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17beta-Hydroxy-11beta-[4-(1-methyl-3-butylureido)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C33H42N2O3
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1
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| 1 |
IC50 = 0.79 nM
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CP0422904
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17beta-Hydroxy-11beta-[4-(1-methyl-7-oxo-1,8-diaza-dodecyl)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C38H52N2O3
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1
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| 1 |
IC50 = 0.9 nM
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CP0449766
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(8S,11R,13S,14R,17S)-17-(3,5-difluoro-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H33F2NO3
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1
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| 1 |
IC50 = 0.91 nM
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CP0467204
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(8S,11R,13S,14R,17S)-17-(4-bromo-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H34BrNO3
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1
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| 1 |
IC50 = 0.94 nM
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CP0490381
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(3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phenyl]-5-ethyl-15'-methyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C31H38N2O2
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1
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| 1 |
IC50 = 0.98 nM
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CP0490394
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(3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-methoxyphenyl)-15'-methyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C30H34FNO3
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1
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| 1 |
IC50 = 1 nM
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CP0382006
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17beta-Hydroxy-11beta-[4-(9-bromnonoxy)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C36H47BrO3
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1
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| 1 |
IC50 = 1 nM
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CP0467221
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-(3-fluoro-phenylethynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H34FNO3
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1
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| 1 |
IC50 = 1 nM
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CP0428831
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(1'S,2R,2'S,6'R,9'R)-9'-[4-(dimethylamino)phenyl]-6'-methyl-3-methylidene-8'-oxaspiro[oxolane-2,5'-tetracyclo[8.8.0.0^{2,6}.0^{11,16}]octadecane]-10',15'-dien-14'-one
Show/Hide
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C30H37NO3
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1
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| 1 |
IC50 = 1 nM
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CP0528558
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(8S,11R,13S,14R,17S)-17-(2-chloro-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C33H34ClNO3
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1
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| 1 |
IC50 = 1.1 nM
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CP0519243
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17beta-Hydroxy-11beta-[4-(1-methyl-6,9-dioxo-1-aza-5,10-dioxa-undecyl)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C36H45NO6
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1
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| 1 |
IC50 = 1.2 nM
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CP0522863
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17beta-Hydroxy-11beta-[4-hydroxyphenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C27H30O3
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1
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| 1 |
IC50 = 1.3 nM
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CP0422760
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17beta-Hydroxy-11beta-[4-(N-methynonylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C37H51NO2
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1
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| 1 |
IC50 = 1.4 nM
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CP0399452
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(8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-17-hydroxy-13-methyl-17-phenylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C33H35NO3
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1
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| 1 |
IC50 = 1.4 nM
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CP0464693
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-(2-fluoro-phenylethynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C33H34FNO3
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1
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| 1 |
IC50 = 1.4 nM
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CP0410432
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]propane-2-sulfonamide
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C15H17N3O2S
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1
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| 1 |
IC50 = 1.5 nM
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CP0522866
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17beta-Hydroxy-11beta-[4-(1-oxo-4-methoxycarbonyl-N-methylbutylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C34H41NO5
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1
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| 1 |
IC50 = 1.55 nM
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CP0449765
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-thiophen-3-ylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C31H33NO3S
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1
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| 1 |
IC50 = 1.6 nM
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CP0458934
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-p-tolylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C34H37NO3
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1
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| 1 |
IC50 = 1.6 nM
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CP0481371
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17beta-Hydroxy-11beta-{4-[1,14,14-trimethyl-11-(2-methylpropyl)-2,9,12-trioxo-1,3,10-triaza-13-oxa-pentadecyl]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C45H63N3O6
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1
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| 1 |
IC50 = 1.7 nM
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CP0382007
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17beta-Hydroxy-11beta-[4-(1-oxo-5-methoxycarbonyl-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C35H43NO5
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1
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| 1 |
IC50 = 1.8 nM
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CP0528298
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17beta-Hydroxy-11beta-[4-(9-hydroxy-1-methyl-6,9-dioxo-1-aza-5-oxa-nonyl)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C35H43NO6
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1
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| 1 |
IC50 = 2.1 nM
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CP0515568
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17beta-Hydroxy-11beta-{4-[1-methyl-3-(5-methoxycarbonylpentyl)-ureido]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
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C36H46N2O5
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1
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| 1 |
IC50 = 2.2 nM
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CP0284048
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4-chloro-13-(2-chlorophenyl)-6-methyl-11-oxo-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene-5-carbonitrile
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C18H11Cl2N3OS
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1
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| 1 |
IC50 = 2.512 nM
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CP0421973
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-(3-trifluoromethyl-phenylethynyl)-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C34H34F3NO3
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1
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| 1 |
IC50 = 2.7 nM
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CP0436546
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-m-tolylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C34H37NO3
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1
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| 1 |
IC50 = 2.9 nM
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CP0095949
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1-methyl-5-(4-pivaloylphenyl)-1H-pyrrole-2-carbonitrile
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C17H18N2O
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1
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| 1 |
IC50 = 3 nM
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CP0677788
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5-(4-(1-(hydroxyimino)-2,2-dimethylpropyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
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C17H19N3O
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1
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| 1 |
IC50 = 3 nM
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CP0480356
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-(2-trifluoromethyl-phenylethynyl)-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C34H34F3NO3
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1
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| 1 |
IC50 = 3.2 nM
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CP0528553
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-17-(4-methoxy-phenylethynyl)-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C34H37NO4
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1
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| 1 |
IC50 = 3.2 nM
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CP0055012
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ONAPRISTONE
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C29H39NO3
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1
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| 1 |
IC50 = 3.3 nM
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CP0440066
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3-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-5-fluoro-benzonitrile
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C18H14FN3O
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1
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| 1 |
IC50 = 3.3 nM
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CP0477870
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5-(3,3-diethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
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C18H19N3O
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2
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| 1 |
IC50 = 3.3 nM
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| 2 |
IC50 = 36 nM
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CP0507964
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(1R,3S,3aR,3bS,10R)-1-Hydroxy-1-isopropenyl-12a-methyl-10-(4-methylsulfanyl-phenyl)-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
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C28H34O3S
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1
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| 1 |
IC50 = 3.3 nM
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CP0437234
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4-[(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-3-oxo-1,2,3,6,8,11,12,13,14,15,16,17-dodecahydro-7-oxa-cyclopenta[a]phenanthren-17-ylethynyl]-benzonitrile
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C34H34N2O3
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1
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| 1 |
IC50 = 3.7 nM
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CP0404871
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5-(7-fluoro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
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C16H14FN3O
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2
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| 1 |
IC50 = 4.1 nM
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| 2 |
IC50 = 5 nM
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CP0500700
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5-(7-fluoro-3,3-dimethyl-2-oxo-1-prop-2-enylindol-5-yl)-1-methylpyrrole-2-carbonitrile
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C19H18FN3O
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1
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| 1 |
IC50 = 4.5 nM
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CP0496631
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(3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyphenyl)-5,15'-dimethyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
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C29H32FNO3
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1
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| 1 |
IC50 = 4.6 nM
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CP0499969
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5-(3-Isopropyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C16H16N4O
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1
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| 1 |
IC50 = 4.7 nM
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CP0404872
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5-(3,3-diethyl-7-fluoro-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C18H18FN3O
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1
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| 1 |
IC50 = 4.9 nM
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CP0371994
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6-(2,3-dichlorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
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C19H20Cl2N2O2
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1
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| 1 |
IC50 = 5 nM
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CP0500699
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5-(4-fluoro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C16H14FN3O
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2
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| 1 |
IC50 = 5.5 nM
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| 2 |
IC50 = 5.9 nM
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CP0486963
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3-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-5-fluoro-benzonitrile
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C19H16FN3O
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1
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| 1 |
IC50 = 5.7 nM
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CP0528556
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-o-tolylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C34H37NO3
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1
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| 1 |
IC50 = 5.8 nM
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CP0487096
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5-(5-hydroxy-5-methyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1-methyl-1H-pyrrole-2-carbonitrile
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C17H18N2O
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1
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| 1 |
IC50 = 6 nM
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CP0523281
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-3-fluorophenyl]ethanesulfonamide
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C14H14FN3O2S
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1
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| 1 |
IC50 = 6 nM
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CP0122638
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5-(5,5-di(furan-2-yl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C23H17N3O4
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2
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| 1 |
IC50 = 6.6 nM
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| 2 |
IC50 = 28.4 nM
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CP0397051
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(1'S,2R,2'S,6'R,9'R)-9'-(4-methoxyphenyl)-6'-methyl-3-methylidene-8'-oxaspiro[oxolane-2,5'-tetracyclo[8.8.0.0^{2,6}.0^{11,16}]octadecane]-10',15'-dien-14'-one
Show/Hide
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C29H34O4
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1
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| 1 |
IC50 = 7 nM
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CP0504345
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5-(5-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C16H16N2O
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1
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| 1 |
IC50 = 7 nM
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CP0421974
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(8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C28H33NO3
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1
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| 1 |
IC50 = 7.5 nM
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CP0273183
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4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-furan-2-carbonitrile
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C15H12N2O3
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1
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| 1 |
IC50 = 8 nM
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CP0410430
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-3-fluorophenyl]methanesulfonamide
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C13H12FN3O2S
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1
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| 1 |
IC50 = 8 nM
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CP0441675
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]methanesulfonamide
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C13H13N3O2S
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1
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| 1 |
IC50 = 8 nM
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CP0553050
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6-(3,5-dichlorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C19H20Cl2N2O2
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1
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| 1 |
IC50 = 8.1 nM
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CP0453570
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6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
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C16H14FNO2
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1
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| 1 |
IC50 = 8.2 nM
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CP0553051
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4,4-diethyl-6-(3-fluoro-5-nitrophenylamino)-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
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C19H20FN3O4
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1
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| 1 |
IC50 = 8.4 nM
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CP0528557
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(8S,11R,13S,14R,17S)-17-(2-bromo-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H34BrNO3
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1
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| 1 |
IC50 = 8.6 nM
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CP0458657
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6-(3-chloro-4-fluorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C19H20ClFN2O2
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1
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| 1 |
IC50 = 9 nM
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CP0489651
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]ethanesulfonamide
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C14H15N3O2S
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1
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| 1 |
IC50 = 9 nM
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CP0501725
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5-(4,4-diethyl-1-methyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-ylamino)-2-fluorobenzonitrile
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C20H20FN3O2
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1
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| 1 |
IC50 = 9.2 nM
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CP0435579
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-trifluoroprop-1-ynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C28H30F3NO3
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1
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| 1 |
IC50 = 9.3 nM
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CP0435576
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(8S,11R,13S,14R,17S)-17-cyclopropylethynyl-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C30H35NO3
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1
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| 1 |
IC50 = 9.6 nM
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CP0915046
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1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimidazole-2-thione
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C20H15N3O2S
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1
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| 1 |
IC50 = 10 nM
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CP0384483
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5-((5R)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C20H17N3O2S
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1
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| 1 |
IC50 = 10 nM
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CP0404867
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5-(3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C16H15N3O
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2
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| 1 |
IC50 = 10 nM
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| 2 |
IC50 = 22 nM
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CP0518744
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5-(5-hydroxy-5-(prop-1-ynyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C19H18N2O
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1
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| 1 |
IC50 = 10 nM
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CP0413128
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]propane-1-sulfonamide
Show/Hide
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C15H17N3O2S
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1
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| 1 |
IC50 = 10 nM
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CP0067982
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1-methyl-5-(2-oxo-5,5-di(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C23H17N3O2S2
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2
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| 1 |
IC50 = 11.3 nM
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| 2 |
IC50 = 60 nM
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CP0390530
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1-Methyl-5-(2-oxo-3-pentyl-2,3-dihydro-1H-benzoimidazol-5-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C18H20N4O
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1
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| 1 |
IC50 = 11.7 nM
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CP0373077
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3-[5-Ethyl-5-(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]-5-fluorobenzonitrile
Show/Hide
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C22H17FN2O3
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1
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| 1 |
IC50 = 11.8 nM
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CP0522104
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-3,5-difluorophenyl]ethanesulfonamide
Show/Hide
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C14H13F2N3O2S
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1
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| 1 |
IC50 = 12 nM
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CP0522106
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-3-(trifluoromethyl)phenyl]ethanesulfonamide
Show/Hide
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C15H14F3N3O2S
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1
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| 1 |
IC50 = 12 nM
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CP0461951
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(8S,11R,13S,14R,17S)-17-(3-chloro-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C33H34ClNO3
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1
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| 1 |
IC50 = 12.5 nM
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CP0468496
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3-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-5-fluoro-benzonitrile
Show/Hide
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C17H13FN2O
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1
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| 1 |
IC50 = 13 nM
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CP0477954
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5-(7-fluoro-3,3-dimethyl-2-oxo-1-propan-2-ylindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C19H20FN3O
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1
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| 1 |
IC50 = 13 nM
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CP0378349
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6-(3-chlorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C19H21ClN2O2
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1
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| 1 |
IC50 = 13.1 nM
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CP0445223
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3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]-5-fluorobenzonitrile
Show/Hide
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C24H15FN2O4
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1
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| 1 |
IC50 = 13.3 nM
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CP0421084
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5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indol]-5'-yl)benzonitrile
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C19H15FN2O
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2
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| 1 |
IC50 = 13.6 nM
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| 2 |
IC50 = 230 nM
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CP0373213
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1-methyl-5-(2-oxo-5,5-diphenyl-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C27H21N3O2
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2
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| 1 |
IC50 = 14.3 nM
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| 2 |
IC50 = 36 nM
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CP0511426
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3-(4,4-diethyl-1-methyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-ylamino)-5-fluorobenzonitrile
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C20H20FN3O2
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1
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| 1 |
IC50 = 14.5 nM
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CP0529597
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5-(5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C21H19N3O2S
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2
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| 1 |
IC50 = 14.6 nM
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| 2 |
IC50 = 75 nM
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CP0432425
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7-(3-Fluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
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C17H16FNO2
|
1
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| 1 |
IC50 = 14.9 nM
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CP0477875
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5-(7-fluoro-1,3,3-trimethyl-2-oxoindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C17H16FN3O
|
1
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| 1 |
IC50 = 15 nM
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CP0468494
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7-(3-Chloro-5-fluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C17H15ClFNO2
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1
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| 1 |
IC50 = 15 nM
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CP0304316
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5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-2-fluoro-benzonitrile
Show/Hide
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C17H13FN2O2
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1
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| 1 |
IC50 = 15.1 nM
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CP0424407
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7-(2,3-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C17H15F2NO2
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1
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| 1 |
IC50 = 15.7 nM
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CP0292709
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1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimidazole-2-thione
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C20H15ClN2S
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1
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| 1 |
IC50 = 17 nM
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CP0920309
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5-(4-(1-(hydroxyimino)propyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
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C15H15N3O
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1
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| 1 |
IC50 = 17 nM
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CP0525965
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5-((5S)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C20H17N3O2S
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1
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| 1 |
IC50 = 17.1 nM
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CP0378277
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(3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phenyl]-15'-methyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C29H34N2O2
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1
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| 1 |
IC50 = 18 nM
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CP0461741
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(8S,11R,13S,14R,17R)-11-(4-dimethylamino-phenyl)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C27H31NO3
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1
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| 1 |
IC50 = 19 nM
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CP0392791
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6-(3-Methoxy-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
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C17H17NO3
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1
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| 1 |
IC50 = 19.5 nM
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CP0462023
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(8S,11R,13S,14R,17S)-17-(4-tert-butyl-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C37H43NO3
|
1
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| 1 |
IC50 = 19.5 nM
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CP0393169
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5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-5'-yl)benzonitrile
Show/Hide
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C20H17FN2O
|
2
|
| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 51 nM
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CP0428055
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1-methyl-5-(2-oxo-1,3-dihydroindol-5-yl)pyrrole-2-carbonitrile
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C14H11N3O
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2
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 80 nM
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CP0433192
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5-(6-fluoro-3,3-dimethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C16H14FN3O
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1
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| 1 |
IC50 = 20.3 nM
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CP0453277
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3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indol]-5'-yl)benzonitrile
Show/Hide
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C19H16N2O
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1
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| 1 |
IC50 = 20.6 nM
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CP0465209
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-pyridin-3-ylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
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C32H34N2O3
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1
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| 1 |
IC50 = 21 nM
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CP0401393
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7-(3-Chloro-4-fluorophenyl)-5,5-di(2-furyl)-1,5-dihydro-4,1-benzoxazepin-2(H)-one
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C23H15ClFNO4
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1
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| 1 |
IC50 = 22.5 nM
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CP0392781
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6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Show/Hide
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C16H13ClFNO2
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1
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| 1 |
IC50 = 23 nM
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CP0501943
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5-(4-(1-hydroxy-2,2-dimethylpropyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C17H20N2O
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1
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| 1 |
IC50 = 24 nM
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CP0267277
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5-(7-methoxy-4-methyl-2-oxochromen-6-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C17H14N2O3
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1
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| 1 |
IC50 = 24 nM
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CP0392041
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5-(3-Isopropyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-4-methyl-thiophene-2-carbonitrile
Show/Hide
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C16H15N3OS
|
1
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| 1 |
IC50 = 24.8 nM
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CP0500701
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5-(1-cyclopentyl-7-fluoro-3,3-dimethyl-2-oxoindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C21H22FN3O
|
1
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| 1 |
IC50 = 25 nM
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CP0401079
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3-(5,5-Dimethyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)-5-fluorobenzonitrile
Show/Hide
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C18H15FN2O2
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1
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| 1 |
IC50 = 25 nM
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CP0272004
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methyl N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]carbamate
Show/Hide
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C25H26N2O2
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1
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| 1 |
IC50 = 25 nM
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CP0131803
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N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]-N-methylacetamide
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C26H28N2O
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1
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| 1 |
IC50 = 25.8 nM
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CP0379086
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3-Fluoro-5-(8-fluoro-4,4-dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
Show/Hide
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C17H12F2N2O2
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1
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| 1 |
IC50 = 26.2 nM
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CP0468497
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3-Fluoro-5-(2-oxo-5,5-dithien-2-yl-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)benzonitrile
Show/Hide
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C24H15FN2O2S2
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1
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| 1 |
IC50 = 26.6 nM
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CP0372731
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3-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-benzonitrile
Show/Hide
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C17H14N2O
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1
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| 1 |
IC50 = 27 nM
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CP0409445
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5-(3-Fluoro-5-nitro-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one
Show/Hide
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C16H13FN2O3
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1
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| 1 |
IC50 = 27 nM
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CP0552050
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5-(7-fluoro-3,3-dimethyl-2-oxo-1-propylindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C19H20FN3O
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1
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| 1 |
IC50 = 27 nM
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CP0415222
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5-(4-(1-hydroxypropyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C15H16N2O
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1
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| 1 |
IC50 = 27 nM
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CP0482005
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8-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dimethylphenanthridin-6-one
Show/Hide
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C18H12F7NO2
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1
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| 1 |
IC50 = 27 nM
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CP0501277
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6-(3,4-difluorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C19H20F2N2O2
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1
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| 1 |
IC50 = 27.4 nM
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CP0508892
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5-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-thiophene-2-carbonitrile
Show/Hide
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C15H12N2OS
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1
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| 1 |
IC50 = 28 nM
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CP0415220
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1-methyl-5-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C16H14N2O
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1
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| 1 |
IC50 = 28 nM
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CP0383107
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5-(3-Chloro-5-fluoro-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one
Show/Hide
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C16H13ClFNO
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1
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| 1 |
IC50 = 29 nM
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CP0439347
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3,3-Dimethyl-5-(5-nitro-thiophen-2-yl)-1,3-dihydro-indol-2-one
Show/Hide
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C14H12N2O3S
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1
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| 1 |
IC50 = 29 nM
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CP0516125
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5-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-4-methyl-thiophene-2-carbonitrile
Show/Hide
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C16H14N2OS
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1
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| 1 |
IC50 = 29 nM
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CP0515548
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3-Fluoro-5-(2-oxo-3-pentyl-2,3-dihydro-1H-benzoimidazol-5-yl)-benzonitrile
Show/Hide
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C19H18FN3O
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1
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| 1 |
IC50 = 29 nM
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CP0500702
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5-(1-ethyl-7-fluoro-3,3-dimethyl-2-oxoindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C18H18FN3O
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1
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| 1 |
IC50 = 29 nM
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CP0486735
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7-(3,5-Dichlorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C17H15Cl2NO2
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1
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| 1 |
IC50 = 29.1 nM
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CP0095790
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6-(3-Chloro-phenyl)-1-ethyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
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C15H13ClN2O
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1
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| 1 |
IC50 = 29.2 nM
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CP0468495
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7-(3,4-Difluorophenyl)-5-ethyl-5-(2-furyl)-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C17H15F2NO2
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1
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| 1 |
IC50 = 29.3 nM
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CP0440119
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3-Fluoro-5-(3-isopropyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-benzonitrile
Show/Hide
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C17H14FN3O
|
1
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| 1 |
IC50 = 29.6 nM
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CP0458659
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6-(3,4-dichlorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C19H20Cl2N2O2
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1
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| 1 |
IC50 = 29.8 nM
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CP0461397
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4-[5-ethyl-5-(furan-2-yl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]furan-2-carbonitrile
Show/Hide
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C20H16N2O4
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1
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| 1 |
IC50 = 29.9 nM
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CP0102421
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6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Show/Hide
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C16H14ClNO2
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1
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| 1 |
IC50 = 30 nM
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CP0448642
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6-(4-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Show/Hide
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C16H14ClNO2
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1
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| 1 |
IC50 = 30 nM
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CP0458624
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6-(4-bromophenylamino)-1,4,4-trimethyl-1H-benzo[d][1,3]oxazine-2(4H)-thione
Show/Hide
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C17H17BrN2OS
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1
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| 1 |
IC50 = 30 nM
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CP0428059
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5-(7-fluoro-3,3-dimethyl-2-oxo-1-prop-2-ynylindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
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C19H16FN3O
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1
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| 1 |
IC50 = 30 nM
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CP0428060
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5-[7-fluoro-3,3-dimethyl-1-(2-methylpropyl)-2-oxoindol-5-yl]-1-methylpyrrole-2-carbonitrile
Show/Hide
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C20H22FN3O
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1
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| 1 |
IC50 = 30 nM
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CP0419029
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7-(3,5-Difluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one
Show/Hide
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C17H15F2NO2
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1
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| 1 |
IC50 = 30 nM
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CP0492164
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-2-fluorophenyl]ethanesulfonamide
Show/Hide
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C14H14FN3O2S
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1
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| 1 |
IC50 = 30 nM
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CP0401392
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7-(3-Chloro-4-fluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C17H15ClFNO2
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1
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| 1 |
IC50 = 30.1 nM
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CP0455452
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3,3-Dimethyl-5-(3-nitro-phenyl)-1,3-dihydro-indol-2-one
Show/Hide
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C16H14N2O3
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2
|
| 1 |
IC50 = 30.6 nM
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| 2 |
IC50 = 509 nM
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CP0558066
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1-(cyclohexylmethyl)-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
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C21H20N2O2
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1
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| 1 |
IC50 = 31 nM
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CP0534990
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5'-(3-chlorophenyl)spiro[cyclopentane-1,3'-indol]-2'(1'H)-one
Show/Hide
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C18H16ClNO
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1
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| 1 |
IC50 = 32 nM
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CP0434108
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6-(3-chlorophenylamino)-4-ethyl-1-methyl-4-(thiophen-2-yl)-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C21H19ClN2O2S
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1
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| 1 |
IC50 = 32.2 nM
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CP0402611
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(1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-ethynyl-1-hydroxy-12a-methyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
|
C28H33NO3
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1
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| 1 |
IC50 = 33 nM
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CP0866903
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5-(5-(hydroxyimino)-5,6,7,8-tetrahydronaphthalen-2-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C16H15N3O
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1
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| 1 |
IC50 = 33 nM
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CP0385142
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N-(4-phenoxyphenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C19H14F3NO3S
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2
|
| 1 |
IC50 = 33 nM
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| 2 |
IC50 = 107 nM
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CP0454951
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6-(3-chloro-4-fluorophenyl)-1-(1-ethylpropyl)-1,3-dihydro-2H-benzimidazole-2-thione
Show/Hide
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C18H18ClFN2S
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1
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| 1 |
IC50 = 33.7 nM
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CP0459125
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17beta-Hydroxy-11beta-[4-(2-carboxy-N-methylethylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
|
C31H37NO4
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1
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| 1 |
IC50 = 34 nM
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CP0437235
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-pyridin-2-ylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
|
C32H34N2O3
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1
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| 1 |
IC50 = 34 nM
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CP0401202
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(1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-hydroxy-12a-methyl-1-prop-1-ynyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
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C29H35NO3
|
1
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| 1 |
IC50 = 34 nM
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CP0566979
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1-hexyl-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C20H20N2O2
|
1
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| 1 |
IC50 = 34 nM
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CP0434744
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7-(3-Chloro-4-fluorophenyl)-5-(2-furyl)-5-(pentafluoroethyl)-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
|
C22H12F6N2O3
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1
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| 1 |
IC50 = 34.1 nM
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CP0439158
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3-Chloro-5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)benzonitrile
Show/Hide
|
C18H15ClN2O2
|
1
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| 1 |
IC50 = 34.6 nM
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CP0504346
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5-(5-hydroxy-5-phenyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C22H20N2O
|
1
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| 1 |
IC50 = 35 nM
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CP0431297
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(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-11-(2-methyl-1,3-benzoxazol-5-yl)-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Show/Hide
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C29H31NO3
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1
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| 1 |
IC50 = 35 nM
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CP0376046
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5'-(3-nitrophenyl)spiro[cyclohexane-1,3'-indol]-2'(1'H)-one
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C19H18N2O3
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2
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| 1 |
IC50 = 36 nM
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| 2 |
IC50 = 96 nM
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CP0404924
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(1S,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-hydroxy-12a-methyl-1-pentafluoroethyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
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C28H32F5NO3
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1
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| 1 |
IC50 = 36 nM
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CP0473625
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5-(4-(1-hydroxyethyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
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C14H14N2O
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1
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| 1 |
IC50 = 36 nM
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CP0410431
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-2-(trifluoromethoxy)phenyl]ethanesulfonamide
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C15H14F3N3O3S
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1
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| 1 |
IC50 = 36 nM
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CP0386959
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methyl N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]-N-methylcarbamate
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C26H28N2O2
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1
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| 1 |
IC50 = 36.2 nM
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CP0442608
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5-(5-isopropyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C22H21N3O2S
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1
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| 1 |
IC50 = 36.5 nM
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CP0452719
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4-(4,4-diethyl-1-methyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-ylamino)-2-fluorobenzonitrile
Show/Hide
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C20H20FN3O2
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1
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| 1 |
IC50 = 37.1 nM
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CP0516099
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5'-(3-nitrophenyl)spiro[cyclopentane-1,3'-indol]-2'(1'H)-one
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C18H16N2O3
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2
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| 1 |
IC50 = 38 nM
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| 2 |
IC50 = 193 nM
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CP0382650
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1-ethyl-5-(7-methoxy-4-methyl-2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
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C18H16N2O3
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1
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| 1 |
IC50 = 38 nM
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CP0435776
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(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-17-pyridin-4-ylethynyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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C32H34N2O3
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1
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| 1 |
IC50 = 39 nM
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CP0390008
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N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]-N-ethylacetamide
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C27H30N2O
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1
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| 1 |
IC50 = 39.5 nM
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CP0299302
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(13S)-4-amino-13-(2-chlorophenyl)-6-methyl-11-oxo-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene-5-carbonitrile
Show/Hide
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C18H13ClN4OS
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1
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| 1 |
IC50 = 39.81 nM
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CP0049604
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2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-quinoline
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C18H18N2O2
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1
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| 1 |
IC50 = 41 nM
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CP0513479
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N-[(8S,11R,13S,14S,17S)-11-(1,3-benzoxazol-5-yl)-13-methyl-3-oxo-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]formamide
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C29H30N2O3
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1
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| 1 |
IC50 = 41 nM
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CP0485194
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6-(3,4-difluorophenylamino)-4,4-diethyl-1-methyl-1H-benzo[d][1,3]oxazine-2(4H)-thione
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C19H20F2N2OS
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1
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| 1 |
IC50 = 42.2 nM
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CP0500463
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N-[(8S,11R,13S,14S,17S)-13-methyl-3-oxo-17-prop-1-ynyl-11-[2-(trifluoromethyl)-1,3-benzoxazol-5-yl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]formamide
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C30H29F3N2O3
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1
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| 1 |
IC50 = 46 nM
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CP0394584
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8-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methyl-5H-phenanthridin-6-one
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C17H10F7NO2
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1
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| 1 |
IC50 = 46 nM
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CP0504347
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5-(4-(hydroxy(thiophen-2-yl)methyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
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C17H14N2OS
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1
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| 1 |
IC50 = 47 nM
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CP0433193
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[5-(5-cyano-1-methylpyrrol-2-yl)-7-fluoro-3,3-dimethyl-2-oxoindol-1-yl]methyl acetate
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C19H18FN3O3
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1
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| 1 |
IC50 = 48 nM
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CP0415221
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4-[3-(4-nitrophenyl)-1-adamantyl]benzonitrile
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C23H22N2O2
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1
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| 1 |
IC50 = 53 nM
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CP0434110
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6-(4-bromophenylamino)-1,4,4-trimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
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C17H17BrN2O2
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1
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| 1 |
IC50 = 54.4 nM
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CP0509427
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5'-(3-chlorophenyl)spiro[cyclohexane-1,3'-indol]-2'(1'H)-one
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C19H18ClNO
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2
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| 1 |
IC50 = 56 nM
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| 2 |
IC50 = 477 nM
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CP0378350
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6-(2,3-dichlorophenylamino)-1,4,4-trimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
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C17H16Cl2N2O2
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1
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| 1 |
IC50 = 56 nM
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CP0401201
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(1S,3S,3aR,3bS,10R)-1-Hydroxy-12a-methyl-10-(4-methylsulfanyl-phenyl)-1-pentafluoroethyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
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C27H29F5O3S
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1
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| 1 |
IC50 = 56 nM
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CP0376773
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1-benzyl-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
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C21H14N2O2
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1
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| 1 |
IC50 = 56 nM
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CP0401548
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1-methyl-5-(2-oxo-5-propyl-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
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C22H21N3O2S
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1
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| 1 |
IC50 = 56.6 nM
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CP0459134
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N-[4-(5-cyano-1-methylpyrrol-2-yl)-2,5-difluorophenyl]ethanesulfonamide
Show/Hide
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C14H13F2N3O2S
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1
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| 1 |
IC50 = 57 nM
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CP0523282
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]-2,2,2-trifluoroethanesulfonamide
Show/Hide
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C14H12F3N3O2S
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1
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| 1 |
IC50 = 58 nM
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CP0456008
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N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]acetamide
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C25H26N2O
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1
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| 1 |
IC50 = 58.4 nM
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CP0522768
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3-(5-Ethyl-2-oxo-5-thien-3-yl-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)-5-fluorobenzonitrile
Show/Hide
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C22H17FN2O2S
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1
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| 1 |
IC50 = 59.2 nM
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CP0402610
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(1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-hydroxy-12a-methyl-1-phenylethynyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
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C34H37NO3
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1
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| 1 |
IC50 = 60 nM
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CP0485215
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2-Fluoro-5-(3-isopropyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-benzonitrile
Show/Hide
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C17H14FN3O
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1
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| 1 |
IC50 = 60.3 nM
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CP0785211
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1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one
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C20H15N3O3
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1
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| 1 |
IC50 = 62 nM
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CP0461396
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7-(2-Fluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
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C17H16FNO2
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1
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| 1 |
IC50 = 62.1 nM
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CP0401394
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7-(3-Chloro-4-fluorophenyl)-5-ethyl-5-(2-furyl)-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C21H17ClFNO3
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1
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| 1 |
IC50 = 62.5 nM
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CP0287555
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1-methyl-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
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C15H10N2O2
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2
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| 1 |
IC50 = 65 nM
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| 2 |
IC50 = 123 nM
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CP0513478
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(8S,11R,13S,14S,17S)-11-(2-ethyl-1,3-benzoxazol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Show/Hide
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C30H33NO3
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1
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| 1 |
IC50 = 65 nM
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CP0486737
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7-(3-Chloro-4-fluorophenyl)-5,5-dithien-2-yl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C23H15ClFNO2S2
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1
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| 1 |
IC50 = 65.2 nM
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CP0480542
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7-(3-Chloro-4-fluorophenyl)-5-methyl-5-thien-2-yl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
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C20H15ClFNO2S
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1
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| 1 |
IC50 = 65.5 nM
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CP0498924
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5-(3-chlorophenyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-one
Show/Hide
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C17H15ClO
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1
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| 1 |
IC50 = 66 nM
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CP0523127
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6-(3-chlorophenylamino)-4-ethyl-1-methyl-4-phenyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C23H21ClN2O2
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1
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| 1 |
IC50 = 66.1 nM
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CP0080905
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5-(3-Chloro-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one
Show/Hide
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C16H14ClNO
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1
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| 1 |
IC50 = 66.4 nM
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CP0474579
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5'-(3-chlorophenyl)spiro[cyclobutane-1,3'-indol]-2'(1'H)-one
Show/Hide
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C17H14ClNO
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1
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| 1 |
IC50 = 70.7 nM
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CP0110333
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6-(5-Bromo-thiophen-2-yl)-2,2,4-trimethyl-1,2-dihydro-quinoline
Show/Hide
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C16H16BrNS
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1
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| 1 |
IC50 = 71 nM
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CP0553052
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4-(4-chlorophenyl)-6-(3-chlorophenylamino)-4-ethyl-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
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C23H20Cl2N2O2
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1
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| 1 |
IC50 = 71.8 nM
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CP0377451
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17beta-Hydroxy-11beta-{4-[11-carboxy-1,13-dimethyl-2,9-dioxo-1,3,10-triaza-tetradecyl]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C41H55N3O6
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1
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| 1 |
IC50 = 72 nM
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CP0422905
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17beta-Hydroxy-11beta-{4-[1-methyl-3-(5-carboxypentyl)-ureido]-phenyl}-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C35H44N2O5
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1
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| 1 |
IC50 = 72 nM
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CP0811076
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1-Isopropyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
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C16H15N3O3
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1
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| 1 |
IC50 = 73.1 nM
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CP0465954
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4-(4,4-Diethyl-3,4-dihydro-1,3-dioxoisoquinolin-2(1H)-yl) benzonitrile
Show/Hide
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C20H18N2O2
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1
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| 1 |
IC50 = 74 nM
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CP0456006
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N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]-N-methylmethanesulfonamide
Show/Hide
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C25H28N2O2S
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1
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| 1 |
IC50 = 74 nM
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CP0441676
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]acetamide
Show/Hide
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C14H13N3O
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1
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| 1 |
IC50 = 75 nM
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CP0459136
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]propanamide
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C15H15N3O
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1
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| 1 |
IC50 = 76 nM
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CP0485214
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6-(3-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
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C16H15FN2O
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1
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| 1 |
IC50 = 77.9 nM
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CP0377845
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5-(2,2,4-Trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbaldehyde
Show/Hide
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C17H17NOS
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1
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| 1 |
IC50 = 78 nM
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CP0377449
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17beta-Hydroxy-11beta-[4-(1-oxo-5-carboxy-N-methylpentylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
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C34H41NO5
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1
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| 1 |
IC50 = 78 nM
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CP0441674
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N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]butanamide
Show/Hide
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C16H17N3O
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1
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| 1 |
IC50 = 78 nM
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CP0383421
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3-Fluoro-5-(5-isopropyl-5-thien-2-yl-2-thioxo-1,2,3,5-tetrahydo-4,1-benzoxazepin-7-yl)benzonitrile
Show/Hide
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C23H19FN2OS2
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1
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| 1 |
IC50 = 78.2 nM
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CP0538097
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5-(3,4-dichlorophenyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-one
Show/Hide
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C17H14Cl2O
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1
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| 1 |
IC50 = 79 nM
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CP0166403
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4-amino-13-(2-chlorophenyl)-6-methyl-11-oxo-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene-5-carbonitrile
Show/Hide
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C18H13ClN4OS
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1
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| 1 |
IC50 = 79.43 nM
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CP0516153
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(3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-methyl-2-methylidene-2H-spiro[1,4-oxazole-3,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-5'-one
Show/Hide
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C29H31NO3
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1
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| 1 |
IC50 = 82 nM
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CP0422914
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(1R,3S,3aR,3bS,10R)-1-Hydroxy-10-(4-methoxy-phenyl)-12a-methyl-1-(4-trifluoromethyl-phenylethynyl)-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
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C34H33F3O4
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1
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| 1 |
IC50 = 82 nM
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CP0434745
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7-(3-Chloro-4-fluorophenyl)-5-(2-furyl)-5-(pentafluoroethyl)-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
|
C21H12ClF6NO3
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1
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| 1 |
IC50 = 82.4 nM
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CP0515549
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3-(3-Cyclohexyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-5-fluoro-benzonitrile
Show/Hide
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C20H18FN3O
|
1
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| 1 |
IC50 = 83.6 nM
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CP0367543
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6-(3-Nitro-phenyl)-3H-benzothiazol-2-one
Show/Hide
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C13H8N2O3S
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1
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| 1 |
IC50 = 83.8 nM
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CP0480530
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5'-(3-chlorophenyl)spiro[cyclopropane-1,3'-indol]-2'(1'H)-one
Show/Hide
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C16H12ClNO
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1
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| 1 |
IC50 = 85 nM
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CP0513480
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(8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-17-prop-1-ynyl-11-[2-(trifluoromethyl)-1,3-benzoxazol-5-yl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Show/Hide
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C29H28F3NO3
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1
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| 1 |
IC50 = 85 nM
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CP0486736
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7-(3-Chloro-4-fluorophenyl)-5,5-diphenyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
|
C27H19ClFNO2
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1
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| 1 |
IC50 = 88 nM
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CP0421198
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1-Cyclopentyl-6-(3,4-difluoro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C18H16F2N2O
|
1
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| 1 |
IC50 = 96.8 nM
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CP0434109
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6-(3,4-dichlorophenylamino)-1,4,4-trimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C17H16Cl2N2O2
|
1
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| 1 |
IC50 = 100 nM
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CP0519242
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17beta-Hydroxy-11beta-[4-(1-oxo-4-carboxy-N-methylbutylamino)-phenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one
Show/Hide
|
C33H39NO5
|
1
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| 1 |
IC50 = 100 nM
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CP0514306
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6-(3,5-Dichloro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
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C16H14Cl2N2O
|
1
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| 1 |
IC50 = 100 nM
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CP0401397
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3-(5-Ethyl-2-oxo-5-thiophen-2-yl-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-5-fluoro-benzonitrile
Show/Hide
|
C22H17FN2O2S
|
1
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| 1 |
IC50 = 100 nM
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CP0445219
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7-(4-Fluorophenyl)-5,5-dimethyl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
|
C17H16FNO2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0430985
|
5-(3,5-Dichloro-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one
Show/Hide
|
C16H13Cl2NO
|
1
|
| 1 |
IC50 = 100.1 nM
|
|
|
|
CP0431296
|
(8S,11R,13S,14S,17S)-11-(1,3-benzoxazol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Show/Hide
|
C28H29NO3
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0082137
|
4-(2,2,4-Trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbaldehyde
Show/Hide
|
C17H17NOS
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0457132
|
3-Methyl-5-(3-nitro-phenyl)-1,3-dihydro-indol-2-one
Show/Hide
|
C15H12N2O3
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0266550
|
2,2,4-Trimethyl-9-nitro-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H20N2O3
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0424408
|
7-(3-Chloro-4-fluorophenyl)-4,5,5-trimethyl-1,3,4,5-tetrahydro-H-1,4-benzodiazepin-2-one
Show/Hide
|
C18H18ClFN2O
|
1
|
| 1 |
IC50 = 104.7 nM
|
|
|
|
CP0194318
|
2,2,4-Trimethyl-6-(3-methyl-thiophen-2-yl)-1,2-dihydro-quinoline
Show/Hide
|
C17H19NS
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0486962
|
6-(3-Chloro-4-fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H14ClFN2O
|
1
|
| 1 |
IC50 = 105.6 nM
|
|
|
|
CP0502415
|
6-(3-Chloro-4-fluoro-phenyl)-1-cyclobutyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C17H14ClFN2O
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0466499
|
4-(5-Ethyl-2-oxo-5-thien-2-yl-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)thiophene-2-carbonitrile
Show/Hide
|
C20H16N2O2S2
|
1
|
| 1 |
IC50 = 107.6 nM
|
|
|
|
CP0906688
|
5-(4-(1-(hydroxyimino)ethyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0441201
|
4-(4,4-Diallyl-3,4-dihydro-1,3-dioxoisoquinolin-2(1H)-yl)benzonitrile
Show/Hide
|
C22H18N2O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0540315
|
3-bromo-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H14BrNO3S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0049605
|
6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H15ClN2O
|
1
|
| 1 |
IC50 = 112.8 nM
|
|
|
|
CP0306091
|
1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C20H15ClN2O
|
1
|
| 1 |
IC50 = 112.8 nM
|
|
|
|
CP0523916
|
1-methyl-5-(4-propionylphenyl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C15H14N2O
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0401395
|
7-(3-Chloro-4-fluorophenyl)-5-ethyl-5-thien-3-yl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one
Show/Hide
|
C21H17ClFNO2S
|
1
|
| 1 |
IC50 = 116.7 nM
|
|
|
|
CP0372028
|
5-(4-(hydroxy(phenyl)methyl)phenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H16N2O
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0426134
|
N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]methanesulfonamide
Show/Hide
|
C24H26N2O2S
|
1
|
| 1 |
IC50 = 118.9 nM
|
|
|
|
CP0525964
|
5-(5-ethyl-1-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C22H21N3O2S
|
1
|
| 1 |
IC50 = 119.8 nM
|
|
|
|
CP0439304
|
4-(3,4-Dihydro-1,3-dioxo-4,4-dipropylisoquinolin-2(1H)-yl)benzonitrile
Show/Hide
|
C22H22N2O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0233743
|
6-(5-chlorothiophen-2-yl)chromen-2-one
Show/Hide
|
C13H7ClO2S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0558068
|
5-[7-(diethylamino)-2-oxochromen-6-yl]-1H-pyrrole-2-carbonitrile
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0456011
|
N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]-N-methylhexanamide
Show/Hide
|
C30H36N2O
|
1
|
| 1 |
IC50 = 124.6 nM
|
|
|
|
CP0522105
|
N-[3-cyano-4-(5-cyano-1-methylpyrrol-2-yl)phenyl]ethanesulfonamide
Show/Hide
|
C15H14N4O2S
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0499481
|
5-(3-Chloro-phenyl)-3-ethyl-1,3-dihydro-indol-2-one
Show/Hide
|
C16H14ClNO
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0548282
|
4-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
Show/Hide
|
C16H8F7NO2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0514301
|
6-(3-Chloro-4-fluoro-phenyl)-1-cyclopentyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C18H16ClFN2O
|
1
|
| 1 |
IC50 = 134.7 nM
|
|
|
|
CP0495034
|
3-Fluoro-5-(2-oxo-3-phenyl-2,3-dihydro-1H-benzoimidazol-5-yl)-benzonitrile
Show/Hide
|
C20H12FN3O
|
1
|
| 1 |
IC50 = 137.3 nM
|
|
|
|
CP0401396
|
3-Fluoro-5-(5-isopropyl-2-oxo-5-thien-2-yl-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)benzonitrile
Show/Hide
|
C23H19FN2O2S
|
1
|
| 1 |
IC50 = 138.3 nM
|
|
|
|
CP0485706
|
5-(2-oxochromen-6-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C14H8N2O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0514524
|
5-(2-oxochromen-6-yl)thiophene-2-carbonitrile
Show/Hide
|
C14H7NO2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0385123
|
3-nitro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H14N2O5S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0514523
|
6-(3-methylthiophen-2-yl)chromen-2-one
Show/Hide
|
C14H10O2S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0394583
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methyl-5H-phenanthridin-6-one
Show/Hide
|
C17H11F6NO2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0408342
|
1-[(3,5-difluorophenyl)methyl]-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C21H12F2N2O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0471222
|
5-(1-benzyl-7-fluoro-3,3-dimethyl-2-oxoindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C23H20FN3O
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0488874
|
N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]-2-methylpropanamide
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0385148
|
3-chloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H14ClNO3S
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0456007
|
N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]hexanamide
Show/Hide
|
C29H34N2O
|
1
|
| 1 |
IC50 = 174.2 nM
|
|
|
|
CP0373212
|
5-(5,5-bis(3-chlorophenyl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C27H19Cl2N3O2
|
1
|
| 1 |
IC50 = 175.1 nM
|
|
|
|
CP0497719
|
1-Cyclobutyl-6-(3,4-difluoro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C17H14F2N2O
|
1
|
| 1 |
IC50 = 175.4 nM
|
|
|
|
CP0456009
|
4-[3-(4-aminophenyl)-1-adamantyl]benzonitrile
Show/Hide
|
C23H24N2
|
1
|
| 1 |
IC50 = 177.7 nM
|
|
|
|
CP0376776
|
1-hexyl-5-(7-methoxy-4-methyl-2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C22H24N2O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0558214
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dimethylphenanthridin-6-one
Show/Hide
|
C18H13F6NO2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0462941
|
5-(3-Chloro-phenyl)-3-methyl-1,3-dihydro-indol-2-one
Show/Hide
|
C15H12ClNO
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0437427
|
(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-(3,3-dimethyl-but-1-ynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
|
C31H39NO3
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0476361
|
6-[3-(trifluoromethyl)phenyl]chromen-2-one
Show/Hide
|
C16H9F3O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0376774
|
5-(2-oxochromen-6-yl)-1-[(2,3,4,5,6-pentafluorophenyl)methyl]pyrrole-2-carbonitrile
Show/Hide
|
C21H9F5N2O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0493530
|
N-(4-phenoxyphenyl)naphthalene-1-sulfonamide
Show/Hide
|
C22H17NO3S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0560062
|
5-(1-cyclohexyl-7-fluoro-3,3-dimethyl-2-oxoindol-5-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C22H24FN3O
|
1
|
| 1 |
IC50 = 194 nM
|
|
|
|
CP0500601
|
3-(3,3-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)benzonitrile
Show/Hide
|
C18H15NO
|
1
|
| 1 |
IC50 = 195 nM
|
|
|
|
CP0525963
|
5-(5,5-bis(5-chlorothiophen-2-yl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C23H15Cl2N3O2S2
|
1
|
| 1 |
IC50 = 197.4 nM
|
|
|
|
CP0521793
|
6-(2,3-dichlorophenylamino)-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C16H14Cl2N2O2
|
1
|
| 1 |
IC50 = 205.8 nM
|
|
|
|
CP0467477
|
5-(3-Acetyl-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 206 nM
|
|
|
|
CP0466899
|
6-(3,4-Difluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H14F2N2O
|
1
|
| 1 |
IC50 = 206.6 nM
|
|
|
|
CP0419030
|
7-(3-Chloro-4-fluoro-phenyl)-5-ethyl-5-thiophen-2-yl-1,5-dihydro-benzo[e][1,4]oxazepin-2-one
Show/Hide
|
C21H17ClFNO2S
|
1
|
| 1 |
IC50 = 207.7 nM
|
|
|
|
CP0526583
|
6-(4-fluorophenyl)chromen-2-one
Show/Hide
|
C15H9FO2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0558067
|
1-[(4-fluorophenyl)methyl]-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C21H13FN2O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0481998
|
4-ethyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
Show/Hide
|
C18H13F6NO2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0107714
|
7,9-Difluoro-2,2,4-trimethyl-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H19F2NO
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0238158
|
7-(diethylamino)-6-thiophen-2-ylchromen-2-one
Show/Hide
|
C17H17NO2S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0514521
|
1-ethyl-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C16H12N2O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0472739
|
3-fluoro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H14FNO3S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0401279
|
3,3-dimethyl-5-m-tolyl-2,3-dihydro-1H-inden-1-one
Show/Hide
|
C18H18O
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0490150
|
5-(3-Chloro-phenyl)-3,3-diethyl-1,3-dihydro-indol-2-one
Show/Hide
|
C18H18ClNO
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0428112
|
6-(3-chlorothiophen-2-yl)chromen-2-one
Show/Hide
|
C13H7ClO2S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0565928
|
1-benzyl-5-(7-methoxy-4-methyl-2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C23H18N2O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0228541
|
5-[7-(diethylamino)-2-oxochromen-6-yl]-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C19H19N3O2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0041367
|
3-Bromo-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H15BrN2S
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0526164
|
2-(4-Chlorophenyl)-4,4-diethylisoquinoline-1,3(2H,4H)-DIONE
Show/Hide
|
C19H18ClNO2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0511575
|
4-[7-(dimethylamino)-2-oxochromen-6-yl]benzonitrile
Show/Hide
|
C18H14N2O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0565927
|
5-[7-(diethylamino)-2-oxochromen-6-yl]-1-ethylpyrrole-2-carbonitrile
Show/Hide
|
C20H21N3O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0514471
|
3-methoxy-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H17NO4S
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0476359
|
3-[7-(dimethylamino)-2-oxochromen-6-yl]benzonitrile
Show/Hide
|
C18H14N2O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0556731
|
5-(7-methoxy-4-methyl-2-oxochromen-6-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C16H12N2O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0479056
|
1-methyl-5-(4-(thiophene-2-carbonyl)phenyl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C17H12N2OS
|
1
|
| 1 |
IC50 = 266 nM
|
|
|
|
CP0437682
|
3-Benzyl-5-(3-chloro-phenyl)-3-methyl-1,3-dihydro-indol-2-one
Show/Hide
|
C22H18ClNO
|
1
|
| 1 |
IC50 = 267 nM
|
|
|
|
CP0455964
|
3-chloro-N-[4-(3-methoxyphenoxy)phenyl]benzenesulfonamide
Show/Hide
|
C19H16ClNO4S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0481997
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methoxy-5H-phenanthridin-6-one
Show/Hide
|
C17H11F6NO3
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0164926
|
3-(2,2,4-Trimethyl-1,2-dihydro-quinolin-6-yl)-thiophene-2-carbonitrile
Show/Hide
|
C17H16N2S
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
|
CP0397052
|
(1R,3S,3aR,3bS,10R)-1-Hydroxy-10-(4-methoxy-phenyl)-12a-methyl-1-phenylethynyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
|
C33H34O4
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0387663
|
4-(2-oxochromen-6-yl)benzonitrile
Show/Hide
|
C16H9NO2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0377058
|
1-(naphthalen-2-ylmethyl)-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C25H16N2O2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0386215
|
1-[(4-cyanophenyl)methyl]-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C22H13N3O2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0421197
|
6-(4-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H15FN2O
|
1
|
| 1 |
IC50 = 295.4 nM
|
|
|
|
CP0410032
|
5-(3-Chloro-phenyl)-1,3-dihydro-indol-2-one
Show/Hide
|
C14H10ClNO
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0430638
|
5-(3-Nitro-phenyl)-1,3-dihydro-indol-2-one
Show/Hide
|
C14H10N2O3
|
1
|
| 1 |
IC50 = 299 nM
|
|
|
|
CP0392908
|
5-(3-Methoxy-phenyl)-3,3-dimethyl-1,3-dihydro-indol-2-one
Show/Hide
|
C17H17NO2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0436398
|
6-(2-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Show/Hide
|
C16H14ClNO2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0428057
|
5-(2-oxo-1,3-dihydroindol-5-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C13H9N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0541417
|
5-(4-benzoylphenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C19H14N2O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0428110
|
5-(7-hydroxy-4-methyl-2-oxochromen-6-yl)-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C16H12N2O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0446581
|
3-cyano-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H14N2O3S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0505511
|
6-[4-(dimethylamino)phenyl]chromen-2-one
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0478006
|
8-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
Show/Hide
|
C16H8F7NO2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0283150
|
N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]-N-methylbenzamide
Show/Hide
|
C31H30N2O
|
1
|
| 1 |
IC50 = 311.4 nM
|
|
|
|
CP0917202
|
3,3-dimethyl-5-m-tolyl-2,3-dihydro-1H-inden-1-one oxime
Show/Hide
|
C18H19NO
|
1
|
| 1 |
IC50 = 316 nM
|
|
|
|
CP0946434
|
3-(1-(hydroxyimino)-3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)benzonitrile
Show/Hide
|
C18H16N2O
|
1
|
| 1 |
IC50 = 317 nM
|
|
|
|
CP0395681
|
3,5-dichloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H13Cl2NO3S
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0477629
|
3-chloro-N-(4-phenylphenyl)benzenesulfonamide
Show/Hide
|
C18H14ClNO2S
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0376775
|
6-(5-acetylthiophen-2-yl)chromen-2-one
Show/Hide
|
C15H10O3S
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0397540
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-methylphenanthridin-6-one
Show/Hide
|
C17H11F6NO2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0373078
|
7-(3-Chloro-4-fluorophenyl)-5-propyl-5-thien-2-yl-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
|
C22H19ClFNO2S
|
1
|
| 1 |
IC50 = 349.4 nM
|
|
|
|
CP0372736
|
5-[7-fluoro-3,3-dimethyl-2-oxo-1-(2-phenylethyl)indol-5-yl]-1-methylpyrrole-2-carbonitrile
Show/Hide
|
C24H22FN3O
|
1
|
| 1 |
IC50 = 351 nM
|
|
|
|
CP0511574
|
7-(dimethylamino)-6-phenylchromen-2-one
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0554701
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-propyl-5H-phenanthridin-6-one
Show/Hide
|
C19H15F6NO2
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0468498
|
7-(3-Chloro-4-fluorophenyl)-5-isopropyl-5-thien-2-yl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one
Show/Hide
|
C22H19ClFNO2S
|
1
|
| 1 |
IC50 = 365.7 nM
|
|
|
|
CP0477615
|
3-methoxy-N-[4-(3-methoxyphenoxy)phenyl]benzenesulfonamide
Show/Hide
|
C20H19NO5S
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0110332
|
9-Chloro-2,2,4,7-tetramethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C20H20ClNO
|
1
|
| 1 |
IC50 = 374 nM
|
|
|
|
CP0468478
|
3-[7-(diethylamino)-2-oxochromen-6-yl]benzonitrile
Show/Hide
|
C20H18N2O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0499357
|
7-(diethylamino)-6-[4-(dimethylamino)phenyl]chromen-2-one
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0525408
|
2-chloro-N-methyl-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H16ClNO3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0267637
|
4-amino-13-(2-fluorophenyl)-6-methyl-11-oxo-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene-5-carbonitrile
Show/Hide
|
C18H13FN4OS
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0430825
|
4,4-Diallyl-2-(4-chlorophenyl)isoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C21H18ClNO2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0511573
|
6-(4-acetylphenyl)-7-(diethylamino)chromen-2-one
Show/Hide
|
C21H21NO3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0410427
|
N-[4-[3-(4-cyanophenyl)-1-adamantyl]phenyl]benzamide
Show/Hide
|
C30H28N2O
|
1
|
| 1 |
IC50 = 403.9 nM
|
|
|
|
CP0395682
|
3,4-dichloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H13Cl2NO3S
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0395912
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0490774
|
6-(2-Fluoro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H15FN2O
|
1
|
| 1 |
IC50 = 412.3 nM
|
|
|
|
CP0466900
|
6-(3-Chloro-4-fluoro-phenyl)-1-pentyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C18H18ClFN2O
|
1
|
| 1 |
IC50 = 425.6 nM
|
|
|
|
CP0428108
|
6-(5-methylthiophen-2-yl)chromen-2-one
Show/Hide
|
C14H10O2S
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0514522
|
1-[(4-nitrophenyl)methyl]-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C21H13N3O4
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0395696
|
N-(4-benzylphenyl)-3-chlorobenzenesulfonamide
Show/Hide
|
C19H16ClNO2S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0859350
|
5-(3,4-dichlorophenyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-one oxime
Show/Hide
|
C17H15Cl2NO
|
1
|
| 1 |
IC50 = 456 nM
|
|
|
|
CP0333203
|
6-(3-Chloro-phenyl)-3H-benzothiazol-2-one
Show/Hide
|
C13H8ClNOS
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0035629
|
9-Bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H17BrFNO
|
1
|
| 1 |
IC50 = 461 nM
|
|
|
|
CP0468479
|
7-(dimethylamino)-6-(4-fluorophenyl)chromen-2-one
Show/Hide
|
C17H14FNO2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0499356
|
N-[4-[7-(diethylamino)-2-oxochromen-6-yl]phenyl]acetamide
Show/Hide
|
C21H22N2O3
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0385124
|
3-methoxy-N-methyl-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C20H19NO4S
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0428113
|
1-[(4-cyanophenyl)methyl]-5-(7-methoxy-4-methyl-2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C24H17N3O3
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0299601
|
9-Fluoro-2,2,4-trimethyl-7-nitro-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H19FN2O3
|
1
|
| 1 |
IC50 = 483 nM
|
|
|
|
CP0857692
|
5-(3-chlorophenyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-one oxime
Show/Hide
|
C17H16ClNO
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0510179
|
N-[4-(3-methoxyphenoxy)phenyl]benzenesulfonamide
Show/Hide
|
C19H17NO4S
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0216130
|
9-Fluoro-2,2,4,7-tetramethyl-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C20H22FNO
|
1
|
| 1 |
IC50 = 499 nM
|
|
|
|
CP0463235
|
1-methyl-5-(1-methyl-2-oxo-5,5-diphenyl-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
Show/Hide
|
C28H23N3O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0070018
|
7-(diethylamino)-6-phenylchromen-2-one
Show/Hide
|
C19H19NO2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0511570
|
4-[7-(diethylamino)-2-oxochromen-6-yl]benzonitrile
Show/Hide
|
C20H18N2O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0399356
|
4-methoxy-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H17NO4S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0476360
|
6-phenylchromen-2-one
Show/Hide
|
C15H10O2
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0511572
|
6-(4-amino-3-nitrophenyl)-7-(diethylamino)chromen-2-one
Show/Hide
|
C19H19N3O4
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0385147
|
3-chloro-N-(4-propan-2-ylphenyl)benzenesulfonamide
Show/Hide
|
C15H16ClNO2S
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0385131
|
N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H15NO3S
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0070015
|
6-thiophen-2-ylchromen-2-one
Show/Hide
|
C13H8O2S
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0424304
|
1-(cyclohexylmethyl)-5-(7-methoxy-4-methyl-2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0387664
|
6-(3,5-difluorophenyl)chromen-2-one
Show/Hide
|
C15H8F2O2
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0467810
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0386474
|
1-[(4-fluorophenyl)methyl]-5-(7-methoxy-4-methyl-2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C23H17FN2O3
|
1
|
| 1 |
IC50 = 570 nM
|
|
|
|
CP0442867
|
1-benzyl-5-[7-(diethylamino)-2-oxochromen-6-yl]pyrrole-2-carbonitrile
Show/Hide
|
C25H23N3O2
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0536358
|
(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-17-(3-methoxy-prop-1-ynyl)-11,13-dimethyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
|
C30H37NO4
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0476358
|
7-(diethylamino)-6-(4-fluorophenyl)chromen-2-one
Show/Hide
|
C19H18FNO2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0525411
|
2,3-dichloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H13Cl2NO3S
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0455960
|
3-chloro-N-methyl-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H16ClNO3S
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0385145
|
4-chloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H14ClNO3S
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0401398
|
7-(3-Chloro-4-fluorophenyl)-5-methyl-1,3-dihydro-H-1,4-benzodiazepin-2-one
Show/Hide
|
C16H12ClFN2O
|
1
|
| 1 |
IC50 = 676.7 nM
|
|
|
|
CP0110335
|
2,2,4-Trimethyl-6-thiophen-2-yl-1,2-dihydro-quinoline
Show/Hide
|
C16H17NS
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0427542
|
7-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
Show/Hide
|
C16H8F7NO2
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0395686
|
2-chloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H14ClNO3S
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0435915
|
6-(4-chlorophenyl)-7-(diethylamino)chromen-2-one
Show/Hide
|
C19H18ClNO2
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0478004
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
Show/Hide
|
C16H9F6NO2
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0554982
|
(1'S,5R)-1-(4-fluorophenyl)-1'-phenylspiro[4H-indazole-5,2'-cyclohexane]-1'-ol
Show/Hide
|
C24H23FN2O
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0099191
|
7-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C19H18ClNO
|
1
|
| 1 |
IC50 = 782 nM
|
|
|
|
CP0089139
|
4-amino-13-(2-chloro-6-fluorophenyl)-6-methyl-11-oxo-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene-5-carbonitrile
Show/Hide
|
C18H12ClFN4OS
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0453790
|
5-(4-acetylphenyl)-1-methyl-1H-pyrrole-2-carbonitrile
Show/Hide
|
C14H12N2O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0424387
|
3-chloro-N-(4-phenylmethoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H16ClNO3S
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0309710
|
2,2,4-Trimethyl-9-phenyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
Show/Hide
|
C25H23NO
|
1
|
| 1 |
IC50 = 811 nM
|
|
|
|
CP0395684
|
3-chloro-N-(4-methoxyphenyl)benzenesulfonamide
Show/Hide
|
C13H12ClNO3S
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0386216
|
1-(cyanomethyl)-5-[7-(diethylamino)-2-oxochromen-6-yl]pyrrole-2-carbonitrile
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0511571
|
7-(diethylamino)-6-(4-nitrophenyl)chromen-2-one
Show/Hide
|
C19H18N2O4
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0441200
|
4-(4,4-Spirohexyl-3,4-dihydro-1,3-dioxoisoquinolin-2(1H)-yl)benzonitrile
Show/Hide
|
C21H18N2O2
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0387662
|
7-methoxy-6-phenylchromen-2-one
Show/Hide
|
C16H12O3
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0402612
|
(1S,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-hydroxy-12a-methyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
|
C26H33NO3
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
|
CP0401019
|
4-chloro-N-methyl-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C19H16ClNO3S
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0510178
|
4-methoxy-N-methyl-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C20H19NO4S
|
1
|
| 1 |
IC50 = 990 nM
|
|
|
|
CP0100988
|
6-(3-Chloro-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C14H11ClN2O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0785688
|
1-Methyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C14H11N3O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0458658
|
4,4-bis(4-chlorophenyl)-6-(3-chlorophenylamino)-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C27H19Cl3N2O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0504993
|
6-(4-bromophenylamino)-1-isopropyl-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C19H21BrN2O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0523777
|
6-(4-bromophenylamino)-1-ethyl-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C18H19BrN2O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0434746
|
7-(3-Chloro-4-fluorophenyl)-5,5-bis(4-chlorophenyl)-1,5-dihydro-4,1-benzoxazepin-2(H)-one
Show/Hide
|
C23H13Cl3FNO2S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0531182
|
3-[5,5-bis(5-chlorothiophen-2-yl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]-5-fluorobenzonitrile
Show/Hide
|
C24H13Cl2FN2O2S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0557503
|
9-fluoro-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5H-phenanthridin-6-one
Show/Hide
|
C16H8F7NO2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0441199
|
2-(4-Chlorophenyl)-4,4-dipropylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C21H22ClNO2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0506290
|
4,4-Spirohexyl-2-(4-chlorophenyl)isoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C20H18ClNO2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0573455
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-8-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0468480
|
3-(2-oxochromen-6-yl)benzonitrile
Show/Hide
|
C16H9NO2
|
1
|
| 1 |
IC50 = 1110 nM
|
|
|
|
CP0495660
|
4-(4,4-Spiropentyl-3,4-dihydro-1,3-dioxoisoquinolin-2(1H)-yl)benzonitrile
Show/Hide
|
C20H16N2O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0380839
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
Show/Hide
|
C20H17F6NO2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0468481
|
6-(furan-2-yl)chromen-2-one
Show/Hide
|
C13H8O3
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0511576
|
7-hydroxy-6-phenylchromen-2-one
Show/Hide
|
C15H10O3
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0441202
|
4,4-Spiropentyl-2-(4-chlorophenyl)isoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C19H16ClNO2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0465949
|
2-(4-Chlorophenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H14ClNO2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0455974
|
3-chloro-N-(4-methylphenyl)benzenesulfonamide
Show/Hide
|
C13H12ClNO2S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0477614
|
N-(4-bromophenyl)-3-chlorobenzenesulfonamide
Show/Hide
|
C12H9BrClNO2S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0395919
|
5-ethyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenanthridin-6-one
Show/Hide
|
C18H13F6NO2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0566854
|
3-chloro-N-phenylbenzenesulfonamide
Show/Hide
|
C12H10ClNO2S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0441198
|
4-(3,4-Dihydro-4,4-dimethyl-1,3-dioxoisoquinolin-2(1H)-yl)benzonitrile
Show/Hide
|
C18H14N2O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0455965
|
2,4,5-trichloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C18H12Cl3NO3S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0477616
|
N-(4-phenoxyphenyl)-1-phenylmethanesulfonamide
Show/Hide
|
C19H17NO3S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0385146
|
N-(4-phenoxyphenyl)naphthalene-2-sulfonamide
Show/Hide
|
C22H17NO3S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0395690
|
N-[4-(4-hydroxyphenoxy)-3-methylphenyl]-3-methoxybenzenesulfonamide
Show/Hide
|
C20H19NO5S
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0455959
|
N-benzyl-2-chloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C25H20ClNO3S
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0489354
|
N-(4-phenoxyphenyl)methanesulfonamide
Show/Hide
|
C13H13NO3S
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0525407
|
N-benzyl-3-chloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C25H20ClNO3S
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0481996
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-hexylphenanthridin-6-one
Show/Hide
|
C22H21F6NO2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0501553
|
6-[4-(dimethylamino)phenyl]-7-hydroxychromen-2-one
Show/Hide
|
C17H15NO3
|
1
|
| 1 |
IC50 = 2590 nM
|
|
|
|
CP0472740
|
N-benzyl-3-methoxy-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C26H23NO4S
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0473976
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-10-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0424503
|
N-(4-phenoxyphenyl)benzamide
Show/Hide
|
C19H15NO2
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0409471
|
6-(4-bromophenylamino)-4,4-dimethyl-1-phenyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C22H19BrN2O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0504992
|
1-benzyl-6-(4-bromophenylamino)-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Show/Hide
|
C23H21BrN2O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0436689
|
3-[3-(3-Chloro-phenyl)-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl]-5-fluoro-benzonitrile
Show/Hide
|
C20H11ClFN3O
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0417710
|
N-benzyl-4-chloro-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C25H20ClNO3S
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0526582
|
6-[4-(dimethylamino)phenyl]-7-methoxychromen-2-one
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
IC50 = 3340 nM
|
|
|
|
CP0480247
|
2-(3-Chlorophenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H14ClNO2
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0424388
|
N-benzyl-4-methoxy-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C26H23NO4S
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0446577
|
N-[4-(3-methoxyphenoxy)phenyl]benzamide
Show/Hide
|
C20H17NO3
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0395440
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-propylphenanthridin-6-one
Show/Hide
|
C19H15F6NO2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0478005
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0468477
|
ethyl 7-(diethylamino)-2-oxo-6-phenylchromene-3-carboxylate
Show/Hide
|
C22H23NO4
|
1
|
| 1 |
IC50 = 4070 nM
|
|
|
|
CP0350961
|
2-(2-Chlorophenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H14ClNO2
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0408556
|
N-[4-(4-hydroxyphenoxy)-3-methylphenyl]-3-methoxybenzamide
Show/Hide
|
C21H19NO4
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0063115
|
US10196374, Example 1
Show/Hide
|
C27H28F2N4O3
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0488049
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0424502
|
N-(4-benzoylphenyl)-3-chlorobenzenesulfonamide
Show/Hide
|
C19H14ClNO3S
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0490652
|
2-(4-Fluorophenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H14FNO2
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0417384
|
5-butylphenanthridin-6-one
Show/Hide
|
C17H17NO
|
1
|
| 1 |
IC50 = 7100 nM
|
|
|
|
CP0380838
|
5-butyl-2-ethylphenanthridin-6-one
Show/Hide
|
C19H21NO
|
1
|
| 1 |
IC50 = 7800 nM
|
|
|
|
CP0459433
|
5-butyl-2-methylphenanthridin-6-one
Show/Hide
|
C18H19NO
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0390091
|
N-benzyl-4-cyano-N-(4-phenoxyphenyl)benzenesulfonamide
Show/Hide
|
C26H20N2O3S
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0323264
|
4,4-Dimethyl-2-p-tolylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 = 8100 nM
|
|
|
|
CP0487874
|
5-butyl-2-tert-butylphenanthridin-6-one
Show/Hide
|
C21H25NO
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0459434
|
5-butyl-2-(hydroxymethyl)phenanthridin-6-one
Show/Hide
|
C18H19NO2
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0134159
|
1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimidazole-2-thione
Show/Hide
|
C20H15ClN2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0286432
|
1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C20H15ClN2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0779089
|
1-Benzyl-5-(3-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C20H15N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0480349
|
2-(3-Fluorophenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H14FNO2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0395918
|
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-nonylphenanthridin-6-one
Show/Hide
|
C25H27F6NO2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0399790
|
1-Benzyl-3-phenylquinazoline-2,4(1H,3H)-dione
Show/Hide
|
C21H16N2O2
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0460684
|
2-(4-Methoxyphenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0417385
|
5-butyl-2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-methoxyphenanthridin-6-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0384687
|
2-(2-Fluorophenyl)-4,4-dimethylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H14FNO2
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0386214
|
1-(cyanomethyl)-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile
Show/Hide
|
C16H9N3O2
|
1
|
| 1 |
IC50 = 15800 nM
|
|
|
|
CP0386151
|
4,4-Dimethyl-2-phenylisoquinoline-1,3(2H,4H)-dione
Show/Hide
|
C17H15NO2
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0511713
|
3-Phenyl-1-propylquinazoline-2,4(1H,3H)-dione
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0047174
|
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
Show/Hide
|
C21H28O5
|
2
|
| 1 |
IC50 = 27000 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0473612
|
6-(3-pyridin-3-ylphenyl)chromen-2-one
Show/Hide
|
C20H13NO2
|
1
|
| 1 |
IC50 = 27900 nM
|
|
|
|
CP0465947
|
1-Ethyl-3-phenylquinazoline-2,4(1H,3H)-dione
Show/Hide
|
C16H14N2O2
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0465969
|
1-Methyl-3-phenylquinazoline-2,4(1H,3H)-dione
Show/Hide
|
C15H12N2O2
|
1
|
| 1 |
IC50 = 84000 nM
|
|
|
|
CP0439514
|
(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-(3-dimethylamino-prop-1-ynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
|
C30H38N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0524349
|
(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-17-(3-hydroxy-3-methyl-but-1-ynyl)-11,13-dimethyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
Show/Hide
|
C30H37NO4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402608
|
(1R,3S,3aR,3bS,10R)-1-Ethynyl-1-hydroxy-10-(4-methoxy-phenyl)-12a-methyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
|
C27H30O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0404922
|
(1R,3S,3aR,3bS,10R)-1-Hydroxy-1-isopropenyl-10-(4-methanesulfonyl-phenyl)-12a-methyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
|
C28H34O5S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0428833
|
(1R,3S,3aR,3bS,10R)-1-Hydroxy-10-(4-methoxy-phenyl)-12a-methyl-1-prop-1-ynyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one
Show/Hide
|
C28H32O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0397810
|
4-[3-[4-(dibenzylamino)phenyl]-1-adamantyl]benzonitrile
Show/Hide
|
C37H36N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0421856
|
(5S)-1-(4-fluorophenyl)-1'-phenylspiro[4H-indazole-5,6'-cyclohexene]
Show/Hide
|
C24H21FN2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0551910
|
(1'S,5R)-1-(4-fluorophenyl)-1'-phenylspiro[4H-indazole-5,2'-cycloheptane]-1'-ol
Show/Hide
|
C25H25FN2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0459135
|
N-[2-cyano-4-(5-cyano-1-methylpyrrol-2-yl)phenyl]methanesulfonamide
Show/Hide
|
C14H12N4O2S
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
