Brief Information of the Compound and Protein
Compound Name
3-Fluoro-5-(8-fluoro-4,4-dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile
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PubChem ID
CID: 9879853
SID: 14845924
Canonical SMILES
CC1(C)OC(=O)Nc2c(F)cc(cc12)-c1cc(F)cc(c1)C#N
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Compound Formula C17H12F2N2O2
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 98.8 nM
   TI
   LI
   LO
   TS
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 = 26.2 nM
   TI
   LI
   LO
   TS