Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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 PubChem ID
CID: 23433683
Canonical SMILES
CC1=CC(C)(C)Nc2ccc-3c(COc4ccccc-34)c12
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Compound Formula C19H19NO
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 111 nM
   TI
   LI
   LO
   TS
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 138 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 83.18 nM
2 Ki = 84 nM