Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[1-(2-Ethyl-phenyl)-meth-(Z)-ylidene]-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
    Show/Hide
 PubChem ID
CID: 10873317
SID: 15918344
Canonical SMILES
CCc1ccccc1\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
    Show/Hide
Compound Formula C28H26FNO
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.3 nM