General Information of the Compound
Compound ID
CP0397810
Compound Name
4-[3-[4-(dibenzylamino)phenyl]-1-adamantyl]benzonitrile
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Structure
Formula
C37H36N2
Molecular Weight
508.709
Canonical SMILES
N#Cc1ccc(cc1)C12CC3CC(C1)CC(C3)(C2)c1ccc(cc1)N(Cc1ccccc1)Cc1ccccc1
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InChI
InChI=1S/C37H36N2/c38-24-28-11-13-33(14-12-28)36-20-31-19-32(21-36)23-37(22-31,27-36)34-15-17-35(18-16-34)39(25-29-7-3-1-4-8-29)26-30-9-5-2-6-10-30/h1-18,31-32H,19-23,25-27H2
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InChIKey
YXYZUSSQQRLDOP-UHFFFAOYSA-N
Physicochemical Property
logP
8.55468
Rotatable Bonds
7
Heavy Atom Count
39
Polar Areas
27.03
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118727013
ChEMBL ID
CHEMBL3397791
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01172, Progesterone receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 > 1000 nM
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