Brief Information of the Compound and Protein
Compound Name
2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-quinoline
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PubChem ID
CID: 10494026
SID: 15518752
Canonical SMILES
CC1=CC(C)(C)Nc2ccc(cc12)-c1cccc(c1)[N+]([O-])=O
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Compound Formula C18H18N2O2
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 41 nM
2 Ki = 19.95 nM
3 Ki = 20 nM