Brief Information of the Compound and Protein
Compound Name
4-fluoro-3-(2-sulfanylidenespiro[1H-indole-3,1'-cyclohexane]-5-yl)benzonitrile
    Show/Hide
PubChem ID
CID: 10404759
SID: 15421950
Canonical SMILES
Fc1ccc(cc1-c1ccc2NC(=S)C3(CCCCC3)c2c1)C#N
    Show/Hide
Compound Formula C20H17FN2S
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  1
1
EC50 = 1.4 nM
   TI
   LI
   LO
   TS