General Information of the Compound
| Compound ID |
CP0038813
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| Compound Name |
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
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| Synonyms |
LPCN-1107
4-Pregnene-3,20-dione
57-83-0
Agolutin
Corlutin
Corlutina
Corluvite
Corporin
Corpus luteum hormone
Crinone
Cyclogest
Fologenon
Gesterol
Gestone
Gestormone
Glanducorpin
Gynlutin
Hormoflaveine
Lucorteum
Luteodyn
Luteohormone
Luteol
Lutocyclin
Lutoform
Membrettes
Methylpregnone
Nalutron
Piaponon
Pregn-4-ene-3,20-dione
Pregnenedione
Progekan
Progestasert
Progesterol
Progesterone
Progesterone (oral, preterm labor)
Progesterone (oral, preterm labor), Lipocine
Progesteronum
Progestin
Progestone
Progestron
Progestronol
Prolidon
Proluton
Prometrium
Syngesterone
Syngestrets
Syntolutan
Utrogestan
progesterone
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| Structure |
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| Formula |
C21H30O2
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| Molecular Weight |
314.469
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| Canonical SMILES |
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
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| InChI |
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
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| InChIKey |
RJKFOVLPORLFTN-LEKSSAKUSA-N
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| CAS |
257630-50-5
753497-20-0
57-83-0
8023-13-0
8012-32-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Protein ID: PT01546, ATP-dependent translocase ABCB1
Cell-based Assay
Protein ID: PT04542, Bile salt export pump
Protein ID: PT02509, G-protein coupled bile acid receptor 1
Protein ID: PT00967, Glucocorticoid receptor
Cell-based Assay
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01154, Mineralocorticoid receptor
Protein ID: PT03393, P2X purinoceptor 3
Protein ID: PT01172, Progesterone receptor
Cell-based Assay
Protein ID: PT03795, Solute carrier family 22 member 1
Protein ID: PT04591, Solute carrier family 22 member 2
Protein ID: PT06607, Solute carrier family 22 member 3
Clinical Information about the Compound
Drug 1 ( Progesterone )
| Drug Name | Progesterone | ||
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| Company | Lipocine Inc | ||
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