Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
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 PubChem ID
CID: 5994
SID: 14850243
Canonical SMILES
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
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Compound Formula C21H30O2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CL000162 HeLa S3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
2
Ki = 150 nM
   TI
   LI
   LO
   TS
CL000778 SF-12
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 30.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 1000 nM
2 Ki = 30.5 nM