General Information of the Cell Line
Cell Line ID
CL000162
Cell Line Name
HeLa S3
Synonyms
HeLa s3
HeLa-S3
HELA-S3
HeLa/S3
HeLa.S3
HeLa S 3
HeLa S-3
HeLaS3
HeLa, S3 clone
S3-HeLa
S3 HeLa
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0058
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01546, ATP-dependent translocase ABCB1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0422909
 Compound Info 
[2-[(2-chlorobenzoyl)amino]-6-(4-methoxyphenyl)-3-thiophen-2-yl-1-benzofuran-4-yl] acetate
   Show/Hide
C28H20ClNO5S
  6
1
IC50 = 2.24 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 3.91 nM
 Bioactivity Info 
   TI
   LI
   LO
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3
IC50 = 8.81 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
4
IC50 = 9.58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
5
IC50 = 85.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
6
IC50 = 111 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0422908
 Compound Info 
[6-(4-methoxyphenyl)-2-[(2-methylbenzoyl)amino]-3-thiophen-2-yl-1-benzofuran-4-yl] acetate
   Show/Hide
C29H23NO5S
  6
1
IC50 = 3.71 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 5.11 nM
 Bioactivity Info 
   TI
   LI
   LO
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3
IC50 = 8.9 nM
 Bioactivity Info 
   TI
   LI
   LO
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4
IC50 = 10.5 nM
 Bioactivity Info 
   TI
   LI
   LO
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5
IC50 = 103 nM
 Bioactivity Info 
   TI
   LI
   LO
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6
IC50 = 116 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0036382
 Compound Info 
CAS_52-53-9
   Show/Hide
C27H38N2O4
  3
1
IC50 = 3.87 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 8.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 85.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418685
 Compound Info 
[2-[(3-fluorobenzoyl)amino]-6-(4-methoxyphenyl)-3-thiophen-2-yl-1-benzofuran-4-yl] acetate
   Show/Hide
C28H20FNO5S
  6
1
IC50 = 4.72 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 5.37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 10.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
4
IC50 = 11.5 nM
 Bioactivity Info 
   TI
   LI
   LO
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5
IC50 = 86.6 nM
 Bioactivity Info 
   TI
   LI
   LO
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6
IC50 = 93.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422913
 Compound Info 
[2-(diacetylamino)-6-(4-methoxyphenyl)-3-thiophen-2-yl-1-benzofuran-4-yl] acetate
   Show/Hide
C25H21NO6S
  6
1
IC50 = 5.16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 5.68 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 13.6 nM
 Bioactivity Info 
   TI
   LI
   LO
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4
IC50 = 14.3 nM
 Bioactivity Info 
   TI
   LI
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5
IC50 = 102 nM
 Bioactivity Info 
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6
IC50 = 105 nM
 Bioactivity Info 
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Protein ID: PT02364, dUTP pyrophosphatase
 Protein Info 
Protein ID: PT00967, Glucocorticoid receptor
 Protein Info 
Protein ID: PT00991, Histone deacetylase 1
 Protein Info 
Protein ID: PT00835, Histone deacetylase 2
 Protein Info 
Protein ID: PT00995, Histone deacetylase 3
 Protein Info 
Protein ID: PT01213, Histone deacetylase 6
 Protein Info 
Protein ID: PT00865, Serine/threonine-protein kinase Chk1
 Protein Info 
Protein ID: PT01252, Serine/threonine-protein kinase PLK1
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0116250
 Compound Info 
7-[4-(4-methylpiperazin-1-yl)anilino]quinoline-5,8-dione
   Show/Hide
 C20H20N4O2  2
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
2
IC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0116251
 Compound Info 
6-[4-(4-methylpiperazin-1-yl)anilino]quinoline-5,8-dione
   Show/Hide
 C20H20N4O2  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma