General Information of the Cell Line
Cell Line ID
CL000838
Cell Line Name
MDR-KB-VCR
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0372
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01546, ATP-dependent translocase ABCB1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0419049
 Compound Info 
[(1S,2R,5S,6S,7S,8R,9R,12R)-5,8,12-triacetyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
   Show/Hide
C28H36O9
  2
1
IC50 < 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533807
 Compound Info 
[(1S,2R,4S,5S,6S,7R,8S,9R,12R)-4,5,8-triacetyloxy-7-benzoyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl] pyridine-3-carboxylate
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C34H39NO11
  2
1
IC50 < 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 64 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558975
 Compound Info 
[(1S,2R,4R,5R,6S,7R,8S,9R,12R)-4,5,8-triacetyloxy-2,6,10,10-tetramethyl-12-[(E)-3-phenylprop-2-enoyl]oxy-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
   Show/Hide
C37H42O11
  2
1
IC50 < 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557816
 Compound Info 
[(1S,2R,5S,6S,7S,9R,12R)-5,12-diacetyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
   Show/Hide
C26H34O7
  2
1
IC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 210 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0317641
 Compound Info 
Encequidar
   Show/Hide
C38H36N6O7
  1
1
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532019
 Compound Info 
[(1S,2R,4R,5R,6S,7R,8R,9R,12R)-4,5,12-triacetyloxy-8-hexanoyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C34H46O11
  2
1
IC50 = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572045
 Compound Info 
[(1S,2R,4R,5R,6S,7S,8R,9R,12R)-4,5,8,12-tetraacetyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C30H38O11
  2
1
IC50 = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558976
 Compound Info 
[(1S,2R,4S,5R,6S,7S,8R,9R,12R)-5,8,12-triacetyloxy-2,6,10,10-tetramethyl-4-[(E)-3-phenylprop-2-enoyl]oxy-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C37H42O11
  2
1
IC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548831
 Compound Info 
[(1S,2R,5S,6S,7R,8R,9R,12R)-5,8,12-triacetyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C28H36O9
  2
1
IC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558977
 Compound Info 
[(1S,2R,4S,5R,6S,7R,8S,9R,12R)-5,8-diacetyloxy-4-hydroxy-2,6,10,10-tetramethyl-12-[(E)-3-phenylprop-2-enoyl]oxy-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C35H40O10
  1
1
IC50 = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533806
 Compound Info 
[(1S,2R,4R,5R,6S,7R,8R,9R,12R)-4,5-diacetyloxy-8-hydroxy-2,6,10,10-tetramethyl-12-[(E)-3-phenylprop-2-enoyl]oxy-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C35H40O10
  1
1
IC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0419050
 Compound Info 
[(1S,2R,4R,5R,6S,7R,8S,9R,12R)-4,5,8,12-tetraacetyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C30H38O11
  2
1
IC50 = 56 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557947
 Compound Info 
[(1S,2R,4R,5R,6R,7S,9R,12R)-4,5-diacetyloxy-2,6,10,10-tetramethyl-12-[(E)-3-phenylprop-2-enoyl]oxy-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C35H40O9
  1
1
IC50 = 58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532012
 Compound Info 
[(1S,2R,4S,5S,6S,7S,9R,12R)-4,5-diacetyloxy-12-benzoyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
   Show/Hide
C33H38O9
  1
1
IC50 = 71 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550809
 Compound Info 
CHEBI:66831
   Show/Hide
C33H38O7
  1
1
IC50 = 77 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572529
 Compound Info 
[(1S,2R,5S,6S,7S,9R,12R)-5-acetyloxy-12-benzoyloxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
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C31H36O7
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558994
 Compound Info 
[(1S,2R,3R,4S,5R,6S,7S,9R,12R)-3,4,5,7-tetraacetyloxy-12-hydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.01,6]dodecan-6-yl]methyl acetate
   Show/Hide
C25H34O13
  2
1
IC50 = 260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 470 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558979
 Compound Info 
[(1S,2R,4R,5R,6S,7R,8S,9R,12R)-5,12-diacetyloxy-4,8-dihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
   Show/Hide
C26H34O9
  2
1
IC50 = 310 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 430 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418510
 Compound Info 
[(1S,2R,4S,5R,6S,7S,9R,12R)-5,7,12-triacetyloxy-4-hydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.01,6]dodecan-6-yl]methyl acetate
   Show/Hide
C23H32O11
  2
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 480 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532013
 Compound Info 
[(1S,2R,3R,4S,5R,6S,7S,9R,12R)-4,5,7,12-tetraacetyloxy-3-hydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.01,6]dodecan-6-yl]methyl acetate
   Show/Hide
C25H34O13
  2
1
IC50 = 390 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418512
 Compound Info 
[(1S,2R,3R,4S,5R,6S,7S,9R,12R)-4,5,7-triacetyloxy-3,12-dihydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.01,6]dodecan-6-yl]methyl acetate
   Show/Hide
C23H32O12
  2
1
IC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 530 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma