General Information of the Cell Line
Cell Line ID
CL000517
Cell Line Name
P4 MAGI CCR5+
Synonyms
P4.R5 MAGI
P4-R5 MAGI
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1H21
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00903, C-C chemokine receptor type 5
 Protein Info 
Compound ID Compound Name Compound Formula
CP0256763
 Compound Info 
2,6-dichloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
   Show/Hide
C23H31Cl2N5O3S
  1
1
IC50 = 0.08 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0211683
 Compound Info 
2-chloro-6-cyano-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
   Show/Hide
C24H31ClN6O3S
  1
1
IC50 = 0.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0330500
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[[2-(2-oxo-1,3-oxazolidin-3-yl)acetyl]-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C27H36ClN5O4S
  1
1
IC50 = 0.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0270340
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[pyridin-3-ylcarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C28H35ClN6O2S
  1
1
IC50 = 0.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0073217
 Compound Info 
6-chloro-N-[(3R)-3-[4-[2-methoxyethoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C26H38ClN5O4S
  1
1
IC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0121272
 Compound Info 
6-chloro-N-[(3R)-3-[4-[hydroxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C23H32ClN5O3S
  1
1
IC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0239466
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[methylcarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C24H34ClN5O2S
  1
1
IC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0278310
 Compound Info 
6-chloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C24H34ClN5O3S
  1
1
IC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0139044
 Compound Info 
5-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4,6-dimethyl-2-N-propan-2-ylpyridine-2,5-dicarboxamide
   Show/Hide
C28H42N6O4S
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0248779
 Compound Info 
2,6-dichloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methyl-1-oxidopyridin-1-ium-3-carboxamide
   Show/Hide
C23H31Cl2N5O4S
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0256764
 Compound Info 
6-chloro-N-[(3R)-3-[4-[(2-cyanoacetyl)-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C25H32ClN5O2S
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0285118
 Compound Info 
6-chloro-N-[(3R)-3-[4-[(2-methoxyacetyl)-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C25H35ClN4O3S
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0283663
 Compound Info 
4-[[[[1-[(2R)-4-[(6-chloro-2,4-dimethylpyridine-3-carbonyl)amino]butan-2-yl]piperidin-4-yl]-(thiophen-3-ylmethyl)carbamoyl]amino]methyl]benzoic acid
   Show/Hide
C31H38ClN5O4S
  1
1
IC50 = 0.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0073219
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[[2-(oxan-4-yl)acetyl]-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C29H41ClN4O3S
  1
1
IC50 = 0.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0239467
 Compound Info 
6-cyano-2,4-dimethyl-N-[(3R)-3-[4-[[2-(oxan-4-yl)acetyl]-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C30H41N5O3S
  1
1
IC50 = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0270180
 Compound Info 
N-[(3R)-3-[4-[acetyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-6-chloro-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C24H33ClN4O2S
  1
1
IC50 = 0.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0084996
 Compound Info 
N-[(3R)-3-[4-[4-methoxy-N-(thiophen-3-ylmethyl)anilino]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
   Show/Hide
C28H37N5O2S
  1
1
IC50 = 1.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0285119
 Compound Info 
N-[(3R)-3-[4-[4-methoxy-N-[(4-methylpyridin-3-yl)methyl]anilino]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
   Show/Hide
C30H40N6O2
  1
1
IC50 = 10.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521251
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[(4-methylpyridin-3-yl)methyl-(pyridin-3-ylcarbamoyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C30H38ClN7O2
  1
1
IC50 = 14.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486975
 Compound Info 
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[(4-methylpyridin-3-yl)methyl-[2-(oxan-4-yl)acetyl]amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
   Show/Hide
C31H44ClN5O3
  1
1
IC50 = 31.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0446179
 Compound Info 
6-chloro-N-[(3R)-3-[4-[dimethylcarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
   Show/Hide
C25H36ClN5O2S
  1
1
IC50 = 48.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma