Brief Information of the Compound and Protein
Compound Name
2,6-dichloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methyl-1-oxidopyridin-1-ium-3-carboxamide
    Show/Hide
PubChem ID
CID: 59458061
SID: 148137776
Canonical SMILES
CONC(=O)N(Cc1ccsc1)C1CCN(CC1)[C@H](C)CCNC(=O)c1c(C)cc(Cl)[n+]([O-])c1Cl
    Show/Hide
Compound Formula C23H31Cl2N5O4S
Compound Structure
Protein Name
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000517 P4 MAGI CCR5+ Homo sapiens (Human)  1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS