General Information of the Cell Line
Cell Line ID
CL000577
Cell Line Name
KB-3-1
Synonyms
KB 3-1
KB3-1
KB31
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2088
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Table of Molecular Bioactivities Related to the Cell Line
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0031182
 Compound Info 
Anilinoquinazoline deriv. 9
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 C16H13ClFN3O2  1
1
IC50 = 80 nM
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CP0394182
 Compound Info 
6-[2-(tert-butylamino)ethoxy]-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine
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 C21H24ClFN4O2  1
1
IC50 = 320 nM
   TI
   LI
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CP0403758
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[6-(2-dimethylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-amine
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 C19H20ClFN4O2  1
1
IC50 = 120 nM
   TI
   LI
   LO
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CP0405229
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[6-(3-diethylamino-propoxy)-7-methoxy-quinazolin-4-yl]-amine
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 C22H26ClFN4O2  1
1
IC50 = 160 nM
   TI
   LI
   LO
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CP0448908
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-amine
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 C22H24ClFN4O2  1
1
IC50 = 190 nM
   TI
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CP0500908
 Compound Info 
1-Amino-3-[4-(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-propan-2-ol
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 C18H18ClFN4O3  1
1
IC50 = 390 nM
   TI
   LI
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CP0500997
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-pyrrolidin-1-yl-ethoxy)-quinazolin-4-yl]-amine
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 C21H22ClFN4O2  1
1
IC50 = 730 nM
   TI
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CP0503274
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[6-(3-dimethylamino-propoxy)-7-methoxy-quinazolin-4-yl]-amine
   Show/Hide
 C20H22ClFN4O2  1
1
IC50 = 150 nM
   TI
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CP0507691
 Compound Info 
1-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-3-methylamino-propan-2-ol
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 C19H20ClFN4O3  1
1
IC50 = 220 nM
   TI
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CP0510290
 Compound Info 
1-[Bis-(2-hydroxy-ethyl)-amino]-3-[4-(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-propan-2-ol
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 C22H26ClFN4O5  1
1
IC50 = 850 nM
   TI
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CP0520312
 Compound Info 
(2R)-1-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxy-3-morpholin-4-ylpropan-2-ol
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 C22H24ClFN4O4  1
1
IC50 = 130 nM
   TI
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CP0530110
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[6-(2-isopropylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-amine
   Show/Hide
 C20H22ClFN4O2  1
1
IC50 = 220 nM
   TI
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CP0545066
 Compound Info 
(3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-methylamino-ethoxy)-quinazolin-4-yl]-amine
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 C18H18ClFN4O2  1
1
IC50 = 350 nM
   TI
   LI
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CP0645842
 Compound Info 
16,19,19-trimethyl-(1S,5S)-2,4,13-trioxatetracyclo[13.3.1.01,5.06,11]nonadeca-6(11),7,9,15-tetraen-3-one
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 C19H22O4  1
1
IC50 > 50000 nM
   TI
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CP0668776
 Compound Info 
7-methoxymethoxy-15,18,18-trimethyl-(1S,5S)-2,4,12-trioxatetracyclo[12.3.1.01,5.06,11]octadeca-6(11),7,9,14-tetraen-3-one
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 C20H24O6  1
1
IC50 > 50000 nM
   TI
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CP0716958
 Compound Info 
7-methoxymethoxy-13,15,15-trimethyl-14-methylene-(1S,5S)-2,4-dioxatetracyclo[11.2.2.01,5.06,11]heptadeca-6(11),7,9-triene-3,12-dione
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 C21H24O6  1
1
IC50 > 50000 nM
   TI
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CP0776521
 Compound Info 
15,18,18-trimethyl-(1S,5S)-2,4,12-trioxatetracyclo[12.3.1.01,5.06,11]octadeca-6(11),7,9,14-tetraen-3-one
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 C18H20O4  1
1
IC50 > 50000 nM
   TI
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CP0776552
 Compound Info 
8-methoxymethoxy-15,18,18-trimethyl-(1S,5S)-2,4,12-trioxatetracyclo[12.3.1.01,5.06,11]octadeca-6(11),7,9,14-tetraen-3-one
   Show/Hide
 C20H24O6  1
1
IC50 > 50000 nM
   TI
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CP0800498
 Compound Info 
15,18,18-trimethyl-(1S,5S)-2,4-dioxatetracyclo[12.3.1.01,5.06,11]octadeca-6(11),7,9,14-tetraene-3,12-dione
   Show/Hide
 C19H20O4  1
1
IC50 > 50000 nM
   TI
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CP0818422
 Compound Info 
8-methoxymethoxy-15,18,18-trimethyl-(1S,5S)-2,4-dioxatetracyclo[12.3.1.01,5.06,11]octadeca-6(11),7,9,14-tetraene-3,12-dione
   Show/Hide
 C21H24O6  1
1
IC50 > 50000 nM
   TI
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   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma