General Information of the Cell Line
Cell Line ID
CL000465
Cell Line Name
KB-ChR-8-5
Synonyms
KB-CH[R]-8-5
KBCh(R)-8-5
KB-8-5
KB 8-5
KB8-5
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_5994
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01171, Prostaglandin D2 receptor 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0389705
 Compound Info 
2-[1-[4-(1H-indole-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H19N3O4
  1
1
IC50 = 4.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0387882
 Compound Info 
2-[1-[4-[(3,4-dichlorophenyl)methoxycarbonylamino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H18Cl2N2O5
  1
1
IC50 = 5.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0420654
 Compound Info 
2-[1-[4-(1-benzofuran-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H18N2O5
  1
1
IC50 = 7.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386063
 Compound Info 
2-[1-[4-[[4-(trifluoromethoxy)benzoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H17F3N2O5
  1
1
IC50 = 8.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0387883
 Compound Info 
2-[1-[4-[(4-chlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17ClN2O4
  1
1
IC50 = 9.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0524697
 Compound Info 
2-[1-[4-[(3-chlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17ClN2O4
  1
1
IC50 = 9.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386064
 Compound Info 
2-[1-[4-(naphthalene-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C29H20N2O4
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380031
 Compound Info 
2-[1-[4-[2-(4-chlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H21ClN2O4
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0056577
 Compound Info 
2-[1-[4-[(3,4-dichlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H16Cl2N2O4
  1
1
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386062
 Compound Info 
2-[1-[4-[[4-(dimethylamino)benzoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H23N3O4
  1
1
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0409058
 Compound Info 
2-[1-[4-[(3,4-dichlorophenyl)carbamoyl]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H16Cl2N2O4
  1
1
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392651
 Compound Info 
2-[1-[4-[(4-phenylbenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C31H22N2O4
  1
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0519814
 Compound Info 
2-[1-[4-[[4-(trifluoromethyl)benzoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H17F3N2O4
  1
1
IC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0476029
 Compound Info 
2-[1-[4-[[(E)-3-(3,4-dichlorophenyl)prop-2-enoyl]amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H18Cl2N2O4
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549646
 Compound Info 
2-[1-[4-[(4-methoxybenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H20N2O5
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0387887
 Compound Info 
2-[1-[4-[3-(3,4-dichlorophenyl)propanoylamino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H20Cl2N2O4
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0420653
 Compound Info 
2-[1-[4-[(4-methylbenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H20N2O4
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0551799
 Compound Info 
2-[1-[4-[2-(3,4-dichlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H20Cl2N2O4
  1
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0484520
 Compound Info 
2-[1-[4-[(4-nitrobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17N3O6
  1
1
IC50 = 28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0432735
 Compound Info 
2-[1-[4-[[2-(3,4-dichlorophenyl)acetyl]amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H18Cl2N2O4
  1
1
IC50 = 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549647
 Compound Info 
2-[1-[4-[(3,4-dichlorophenyl)carbamoylamino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17Cl2N3O4
  1
1
IC50 = 36 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0551800
 Compound Info 
2-[1-[4-[(4-chlorophenyl)carbamoyl]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17ClN2O4
  1
1
IC50 = 38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0387884
 Compound Info 
2-[1-(4-benzamidobenzoyl)isoquinolin-4-yl]acetic acid
   Show/Hide
C25H18N2O4
  1
1
IC50 = 42 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0387881
 Compound Info 
2-[1-[4-[(3,4-dichlorophenyl)methylamino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H18Cl2N2O3
  1
1
IC50 = 43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555896
 Compound Info 
2-[1-[4-[3-(4-chlorophenyl)propoxy]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C27H22ClNO4
  1
1
IC50 = 85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0489856
 Compound Info 
2-[1-[4-[[2-(1-adamantyl)acetyl]amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C30H30N2O4
  1
1
IC50 = 97 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0399653
 Compound Info 
2-[1-[4-[2-(4-chlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]oxyacetic acid
   Show/Hide
C27H21ClN2O5
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392650
 Compound Info 
2-[1-[4-[(4-phenoxybenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C31H22N2O5
  1
1
IC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0531041
 Compound Info 
2-[1-[4-[2-(4-chlorophenyl)ethoxy]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H20ClNO4
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380963
 Compound Info 
2-[1-[4-[(3,4-dichlorophenyl)methoxy]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17Cl2NO4
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386065
 Compound Info 
2-[1-[4-[(2-cyclohexylacetyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H26N2O4
  1
1
IC50 = 220 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0409056
 Compound Info 
2-[1-[4-(cyclohexanecarbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H24N2O4
  1
1
IC50 = 270 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0484522
 Compound Info 
2-[1-[4-(naphthalene-1-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C29H20N2O4
  1
1
IC50 = 350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0476027
 Compound Info 
2-[1-[4-(pyrimidine-2-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C23H16N4O4
  1
1
IC50 = 550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380032
 Compound Info 
2-[1-[4-(oxane-4-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C24H22N2O5
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380962
 Compound Info 
2-[1-[4-[2-(4-chlorophenyl)ethylcarbamoyl]benzoyl]isoquinolin-4-yl]-2-methylpropanoic acid
   Show/Hide
C29H25ClN2O4
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0409057
 Compound Info 
2-[1-[4-[(2-chlorobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C25H17ClN2O4
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0420652
 Compound Info 
2-[1-[4-[(4-cyanobenzoyl)amino]benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C26H17N3O4
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0489810
 Compound Info 
2-[1-[4-(1,3-thiazole-4-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C22H15N3O4S
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0530736
 Compound Info 
2-[1-[4-(pyridine-4-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C24H17N3O4
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555897
 Compound Info 
2-[1-[4-(pyridazine-3-carbonylamino)benzoyl]isoquinolin-4-yl]acetic acid
   Show/Hide
C23H16N4O4
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma