General Information of the Cell Line
Cell Line ID
CL000801
Cell Line Name
Chang Liver
Synonyms
Chang liver
Chang Liver (HeLa derivative)
Chang Cells
Chang
CHL
Category
Cancer cell line
Organism
Homo sapiens (Human)
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02536, Diacylglycerol O-acyltransferase 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0223870
 Compound Info 
CHEMBL3741505
   Show/Hide
C22H22N4O4S
  1
1
IC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0223869
 Compound Info 
CHEMBL3739742
   Show/Hide
C21H26N4O4S
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400124
 Compound Info 
2-[4-[4-[[5-(2-cyclopentylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H31N3O3S
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0070794
 Compound Info 
CHEMBL3741095
   Show/Hide
C23H21F2N3O4S
  1
1
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0448175
 Compound Info 
CHEMBL3741333
   Show/Hide
C22H27N3O5S
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0149070
 Compound Info 
4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenoxy]cyclohexane-1-carboxylic acid
   Show/Hide
C23H23N3O4S
  1
1
IC50 = 28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0235312
 Compound Info 
2-[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H25N3O3S
  1
1
IC50 = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0530183
 Compound Info 
2-[4-[4-[[5-(cyclopentylmethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C23H29N3O3S
  1
1
IC50 = 33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0525068
 Compound Info 
2-[4-[4-[[5-[(2-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H24FN3O3S
  1
1
IC50 = 35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430761
 Compound Info 
2-[4-[4-[[5-[(3-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H24FN3O3S
  1
1
IC50 = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0525067
 Compound Info 
CHEMBL2012631
   Show/Hide
C24H24ClN3O3S
  1
1
IC50 = 57 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0313000
 Compound Info 
CHEMBL3740753
   Show/Hide
C23H29N3O4S
  1
1
IC50 = 66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0573784
 Compound Info 
CHEMBL3741896
   Show/Hide
C23H21F2N3O4S
  1
1
IC50 = 76 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0531336
 Compound Info 
4-[5-[[5-[(3-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]pyridin-2-yl]oxycyclohexane-1-carboxylic acid
   Show/Hide
C22H21ClN4O4S
  1
1
IC50 = 85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430753
 Compound Info 
2-[4-[4-[[5-[(4-fluorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H24FN3O4S
  1
1
IC50 = 91 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430763
 Compound Info 
2-[4-[4-[[5-(2-cyclobutylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C23H29N3O3S
  1
1
IC50 = 91 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400125
 Compound Info 
2-[4-[4-[[5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H25N3O4S
  1
1
IC50 = 107 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0313002
 Compound Info 
2-[4-[4-[[5-[(4-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C24H24FN3O3S
  2
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 131 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0083969
 Compound Info 
4-[5-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]pyridin-2-yl]oxycyclohexane-1-carboxylic acid
   Show/Hide
C22H22N4O4S
  1
1
IC50 = 135 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0522514
 Compound Info 
2-[4-[4-[[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C25H27N3O4S
  1
1
IC50 = 142 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400126
 Compound Info 
2-[4-[4-[[5-[2-(4-fluorophenyl)ethyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C25H26FN3O3S
  1
1
IC50 = 173 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430762
 Compound Info 
2-[4-[4-[[5-[3-(4-fluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C26H28FN3O3S
  1
1
IC50 = 181 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400128
 Compound Info 
(2S)-2-[[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)amino]phenyl]benzoyl]amino]-3-methylbutanoic acid
   Show/Hide
C27H26N4O3S
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0531337
 Compound Info 
CHEMBL3741016
   Show/Hide
C23H21F2N3O5
  1
1
IC50 = 310 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430755
 Compound Info 
2-[4-[4-[(5-phenyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C23H23N3O3S
  1
1
IC50 = 588 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0400131
 Compound Info 
2-[4-[4-[[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
   Show/Hide
C25H27N3O3S
  1
1
IC50 = 590 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0385917
 Compound Info 
2-(3-amino-4-methylanilino)-4-(methylamino)-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrimidine-5-carboxamide
   Show/Hide
 C28H26F3N7O2  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
TZM-bl
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma