General Information of the Cell Line
Cell Line ID
CL000599
Cell Line Name
TZM-bl
Synonyms
TZM
JC53-bl
JC53BL-13
JC.53bl-13
JC53-bl clone 13
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_B478
Tissue Information
Uterus
Disease
Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00903, C-C chemokine receptor type 5
 Protein Info 
Compound ID Compound Name Compound Formula
CP0536130
 Compound Info 
US10167299, Maraviroc
   Show/Hide
C29H41F2N5O
  1
1
EC50 = 1 nM
 Bioactivity Info 
   TI
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CP0861271
 Compound Info 
N-(4-(5-(3,4-diacetylphenyl)-3-oxopentyl)phenyl)benzamide
   Show/Hide
C28H27NO6
  1
1
EC50 = 4850 nM
 Bioactivity Info 
   TI
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   LO
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CP0908195
 Compound Info 
(E)-N-(4-(5-(3,4-diacetylphenyl)-3-oxopent-4-en-1-yl)phenyl)-4-methylbenzamide
   Show/Hide
C29H27NO6
  1
1
EC50 = 11220 nM
 Bioactivity Info 
   TI
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CP0854900
 Compound Info 
N-(4-(5-(3,4-diacetylphenyl)-3-oxopentyl)phenyl)-2-(thiophen-2-yl)acetamide
   Show/Hide
C27H27NO6S
  1
1
EC50 = 15990 nM
 Bioactivity Info 
   TI
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CP0945558
 Compound Info 
(E)-N-(4-(5-(3,4-diacetylphenyl)-3-oxopent-4-en-1-yl)phenyl)-4-nitrobenzamide
   Show/Hide
C28H24N2O8
  1
1
EC50 = 16250 nM
 Bioactivity Info 
   TI
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CP0922186
 Compound Info 
(E)-N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopent-4-en-1-yl)phenyl)-4-methoxybenzamide
   Show/Hide
C25H23NO5
  1
1
EC50 = 16560 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0885053
 Compound Info 
N-(4-(5-(3,4-diacetylphenyl)-3-oxopentyl)phenyl)-4-nitrobenzamide
   Show/Hide
C28H26N2O8
  1
1
EC50 = 16830 nM
 Bioactivity Info 
   TI
   LI
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CP0962499
 Compound Info 
N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopentyl)phenyl)cyclohexanecarboxamide
   Show/Hide
C24H29NO4
  1
1
EC50 = 18340 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0905258
 Compound Info 
N-(4-(5-(3,4-diacetylphenyl)-3-oxopentyl)phenyl)cyclohexanecarboxamide
   Show/Hide
C28H33NO6
  1
1
EC50 = 18770 nM
 Bioactivity Info 
   TI
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CP0953231
 Compound Info 
(E)-N-(4-(5-(3,4-diacetylphenyl)-3-oxopent-4-en-1-yl)phenyl)-4-methoxybenzamide
   Show/Hide
C29H27NO7
  1
1
EC50 = 18850 nM
 Bioactivity Info 
   TI
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CP0858658
 Compound Info 
N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopentyl)phenyl)benzamide
   Show/Hide
C24H23NO4
  1
1
EC50 = 22840 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0945437
 Compound Info 
N-(4-(5-(3,4-diacetylphenyl)-3-oxopentyl)phenyl)-4-methylbenzamide
   Show/Hide
C29H29NO6
  1
1
EC50 = 23140 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0962498
 Compound Info 
(E)-N-(4-(5-(3,4-diacetylphenyl)-3-oxopent-4-en-1-yl)phenyl)cyclohexanecarboxamide
   Show/Hide
C28H31NO6
  1
1
EC50 = 29670 nM
 Bioactivity Info 
   TI
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CP0905259
 Compound Info 
N-(4-(5-(3,4-diacetylphenyl)-3-oxopentyl)phenyl)-4-methoxybenzamide
   Show/Hide
C29H29NO7
  1
1
EC50 = 30630 nM
 Bioactivity Info 
   TI
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CP0878481
 Compound Info 
N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopentyl)phenyl)-4-methylbenzamide
   Show/Hide
C25H25NO4
  1
1
EC50 = 36300 nM
 Bioactivity Info 
   TI
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CP0922187
 Compound Info 
N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopentyl)phenyl)-4-nitrobenzamide
   Show/Hide
C24H22N2O6
  1
1
EC50 = 42460 nM
 Bioactivity Info 
   TI
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CP0858657
 Compound Info 
(E)-N-(4-(5-(3,4-diacetylphenyl)-3-oxopent-4-en-1-yl)phenyl)-2-(thiophen-2-yl)acetamide
   Show/Hide
C27H25NO6S
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
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CP0878480
 Compound Info 
(E)-N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopent-4-en-1-yl)phenyl)-4-nitrobenzamide
   Show/Hide
C24H20N2O6
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
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CP0945556
 Compound Info 
(E)-N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopent-4-en-1-yl)phenyl)benzamide
   Show/Hide
C24H21NO4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0945557
 Compound Info 
(E)-N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopent-4-en-1-yl)phenyl)-2-(thiophen-2-yl)acetamide
   Show/Hide
C23H21NO4S
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
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CP0946961
 Compound Info 
(E)-N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopent-4-en-1-yl)phenyl)cyclohexanecarboxamide
   Show/Hide
C24H27NO4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
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CP0953799
 Compound Info 
(E)-N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopent-4-en-1-yl)phenyl)-4-methylbenzamide
   Show/Hide
C25H23NO4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
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CP0962497
 Compound Info 
(E)-N-(4-(5-(3,4-diacetylphenyl)-3-oxopent-4-en-1-yl)phenyl)benzamide
   Show/Hide
C28H25NO6
  1
1
EC50 > 50000 nM
 Bioactivity Info 
   TI
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CP0893441
 Compound Info 
N-(4-(5-(3,4-dihydroxyphenyl)-3-oxopentyl)phenyl)-2-(thiophen-2-yl)acetamide
   Show/Hide
C23H23NO4S
  1
1
EC50 = 55370 nM
 Bioactivity Info 
   TI
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Protein ID: PT00059, Envelope glycoprotein gp160
 Protein Info 
Protein ID: PT01515, Mu-type opioid receptor
 Protein Info 
Protein ID: PT00005, Reverse transcriptase/RNaseH
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0002124
 Compound Info 
4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1S,5S)-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-phenyl-propyl}-amide
   Show/Hide
 C29H41F2N5O  1
1
CC50 > 1000000 nM
   TI
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   TS
CP0097118
 Compound Info 
4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclohexane-1-carboxamide
   Show/Hide
 C27H39F2N5OS  1
1
CC50 > 200000 nM
   TI
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   LO
   TS
CP0154125
 Compound Info 
4,4-difluoro-N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-(5-methylthiophen-2-yl)propyl]cyclohexane-1-carboxamide
   Show/Hide
 C28H41F2N5OS  1
1
CC50 > 200000 nM
   TI
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CP0485421
 Compound Info 
4,4-difluoro-N-[(1S)-1-(5-fluorothiophen-2-yl)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide
   Show/Hide
 C27H38F3N5OS  1
1
CC50 > 200000 nM
   TI
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CP0531563
 Compound Info 
N-[(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-2-[(4-chlorophenyl)methylamino]acetamide;dihydrochloride
   Show/Hide
 C15H21Cl3N4O2S  1
1
CC50 > 70000 nM
   TI
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CP0549133
 Compound Info 
4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-pyridin-3-ylpropyl]cyclohexane-1-carboxamide
   Show/Hide
 C28H40F2N6O  1
1
CC50 > 100000 nM
   TI
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   TS
CP0553146
 Compound Info 
N'-[(1R)-2-amino-1-[5-(hydroxymethyl)-4-methyl-1,3-thiazol-2-yl]ethyl]-N-(4-chlorophenyl)oxamide
   Show/Hide
 C15H17ClN4O3S  1
1
CC50 > 54000 nM
   TI
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CP0559337
 Compound Info 
5-(4-chloro-3-fluorophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1H-pyrrole-2-carboxamide
   Show/Hide
 C20H25ClFN3O  1
1
CC50 = 12800 nM
   TI
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CP0559469
 Compound Info 
N-[(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-4-(cyclohexylmethoxy)benzamide
   Show/Hide
 C20H27N3O3S  1
1
CC50 = 26500 nM
   TI
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CP0561576
 Compound Info 
N'-[(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-N-[(4-chloro-3-fluorophenyl)methyl]oxamide
   Show/Hide
 C15H16ClFN4O3S  1
1
CC50 > 77600 nM
   TI
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CP0566088
 Compound Info 
5-amino-4-(4-cyanoanilino)-2-[4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy]-N-(3-hydroxypropyl)benzamide
   Show/Hide
 C28H27N5O3  1
1
CC50 > 208 nM
   TI
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CP0576429
 Compound Info 
N-[4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidin-4-yl]-5-[4-(trifluoromethyl)phenyl]-1H-pyrrole-2-carboxamide
   Show/Hide
 C21H21F3N4O2S  1
1
CC50 = 33700 nM
   TI
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CP0868740
 Compound Info 
(R)-N-(2-amino-1-(thiazol-2-yl)ethyl)-5-(4-chlorophenyl)-1H-pyrrole-2-carboxamide
   Show/Hide
 C16H15ClN4OS  1
1
CC50 = 38900 nM
   TI
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CP0958866
 Compound Info 
(S)-N-(2-amino-1-(thiazol-2-yl)ethyl)-5-(4-chlorophenyl)-1H-pyrrole-2-carboxamide
   Show/Hide
 C16H15ClN4OS  1
1
CC50 = 36500 nM
   TI
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   TS
CP0960729
 Compound Info 
(R)-N-(1-(4-(hydroxymethyl)thiazol-2-yl)-2-(piperidin-4-yl)ethyl)-5-(4-(trifluoromethyl)phenyl)-1H-pyrrole-2-carboxamide
   Show/Hide
 C23H25F3N4O2S  1
1
CC50 > 40000 nM
   TI
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   TS
CP0967631
 Compound Info 
(S)-N-(2-amino-1-(5-(hydroxymethyl)thiazol-2-yl)ethyl)-6-chloro-1H-indole-2-carboxamide
   Show/Hide
 C15H15ClN4O2S  1
1
CC50 = 83600 nM
   TI
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Uterus)
Cell Line Name Organism Disease
C-33 A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-independent cervical squamous cell carcinoma
HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
H1HeLa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
L-02
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa S3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SGC-7901
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa Kyoto
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HL2/3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-V1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BEL-7402/5-FU
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
BGC-823
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-MAGI-CCR5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
P4 MAGI CCR5+
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-3-1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
KB-ChR-8-5-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
NCTC 2544
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HEp-2
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
SMMC-7721
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HG5LN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Chang Liver
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
Girardi Heart
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VCR
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
MDR-KB-VIN
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa R1-11
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-T5
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa/STAT3-luc
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HLR-CREB
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A2A
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-A3
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
HeLa-P4
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical adenocarcinoma
C-4-I
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SiHa
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
SK-E2
 Cell Line Info 
Homo sapiens (Human) Uterine corpus leiomyosarcoma
MES-SA/Dx5
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma
MES-SA
 Cell Line Info 
Homo sapiens (Human) Uterine corpus sarcoma